Clinical trials: Brain Network Connectivity
Changes in Brain Network Connectivity
Anesthesia and Functional Connectivity: An Analysis of fMRI Changes
Functional connectivity is defined as a correlation in neural activity between distinct regions of the brain. Several recent studies have demonstrated areas of low-frequency functional connectivity inherent to brain tissue at…
- Trial name
- NCT02196259
- Testing
- Anesthetics, Dissociative
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Parkinsons Disease (PD)
Neuroimaging of Parkinson's
Parkinson's Disease (PD) is a neurodegenerative disorder caused by dysfunction in both subcortical structures and the cortex. The investigators recently discovered a new brain system called the Somato-Cognitive Action Network…
- Trial name
- NCT07024875
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Inattention, Cognitive Training
RECOGNeyes Gaze-Control Training
RECOGNeyes is a computer game developed by members of the research team to improve attention in people who find it hard to "keep their eyes on the task".
- Conditions
- Inattention, Cognitive Training, Cognitive Control, Oculomotor Dysfunction
- Trial name
- NCT06691646
- Testing
- Gaze-control training game
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Substance Use Disorder
Functional Connectivity Changes During Early Recovery as a Marker for Relapse
The study purpose is to examine whether there are structural or functional differences in the brains of individuals who use cocaine or amphetamines as opposed to control participants who have never used cocaine or amphetamines.
- Trial name
- NCT02861820
- Testing
- MRI: Brain Imaging Data Collection
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Alzheimer Disease, Early Onset, Parkinson Disease
Network-based biOmarker Discovery of Neurodegenerative Diseases Using Multimodal Connectivity
The aim of the NODAL clinical trial is to demonstrate the feasibility of new, low-cost, non-invasive biomarkers of neurodegenerative pathologies as early Alzheimer and Parkinson, based on the estimation of the multimodal…
- Trial name
- NODAL (NCT06080659)
- Testing
- fMRI, CONFMEM
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Myopia
Effects of Autostereoscopic 3D Visual Training on Binocular Vision Function of Myopes
This study intends to conduct a relatively comprehensive binocular visual function examination and follow-up on two groups of myopic subjects, one receiving autostereoscopic 3D vision training and the other receiving 2D vision…
- Trial name
- NCT06266910
- Testing
- Visual training video
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Healthy
Trait Anxiety and Defensive Networks
to examine the association between trait and defensive network connectivity and the modulatory effect of oxytocin on it
- Trial name
- NCT02682888
- Testing
- trait anxiety scale, Oxytocin
- Where
- China
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Alcohol Use Disorder
Brain Connectivity Between Networks Implied in Inhibition and Cue-reactivity in Alcohol Use Disorder
Research about patients with alcohol use disorder has shown that task-related brain activation patterns as well as resting-state connectivity (measured with functional magnetic resonance imaging) change with clinical parameters…
- Trial name
- NIQA (NCT05843435)
- Testing
- Go-Nogo-task during functional magnetic resonance imaging, Resting-state functional magnetic resonance imaging
- Where
- Switzerland
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Bern
Stroke
Recovery Prediction of Motor Function Using Neuroimaging Techniques in Subacute Stroke Patients
Prediction of recovery from stroke can assist in the planning of impairment-focused rehabilitation. To achieve better prediction for clinical purposes, this study investigated a new prediction model with low inter-individual…
- Trial name
- NCT03365596
- Testing
- Conventional therapy
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Alcohol Use Disorder
Brain Functional Connectivity in Alcohol Use Disorder
Due to the relapsing nature of alcoholism, excessive alcohol consumption represents a significant cost to US society ($249 billion in 20101). About 64% of those entering treatment will relapse within one year.
- Trial name
- NCT02877849
- Testing
- MRI: Brain Imaging data collection
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Schizophrenia
The Effects of Auditory Stimulation During Sleep on Brain Networks in Schizophrenia
In this research study the investigators will use sleep headbands to measure brain rhythms and to improve their coordination across brain regions. The headbands will be worn at home for multiple nights.
- Trial name
- NCT06386588
- Testing
- Closed loop auditory stimulation during sleep
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Alzheimer Disease
Targeting Default Mode Network Dysfunction in Persons At Risk of Alzheimer's Disease with Non-invasive Techniques
Default mode network (DMN) dysfunction is a well-established feature of Alzheimer's Disease (AD) and is already present in preclinical stages and in subjects at risk for AD, thus offering a potential target for early…
- Trial name
- NEST4AD (NCT05984446)
- Testing
- real-rTMS
- Where
- Italy
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Consciousness Disorder
Consciousness-specific Brain Network Connection of Propofol Sedation and Prolonged Disorders of Consciousness
Consciousness-specific Brain Network Connection of Propofol Sedation and Prolonged Disorders of Consciousness based on Electroencephalography and Auditory Event-related Potentials
- Trial name
- NCT05823454
- Testing
- Different drug dosage
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Premature Ejaculation, Sexual Dysfunction
Brain Networks Implicated in Lifelong Premature Ejaculation Patients
Using Brain Mapping and Cognitive ERPs, the investigatos have searched for a Brain Networks involved during Inhibitory Control in Lifelong Premature Ejaculation (LPE) participants.
- Trial name
- LPE (NCT04850703)
- Testing
- Transcranial Radom Noise Stimulation, Take Dapoxetine, Compare LPE EEG endophenotype between participants and healthy controls
- Where
- Spain
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Moises Domingo
Cerebrovascular Circulation
Blood Brain Flow and Exercise
Cerebral vasodilator responses to CO2 will be measured in young healthy adults, healthy sedentary older adults, and healthy exercise trained older adults.
- Trial name
- NCT02653638
- Testing
- Control, Indomethacin
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Metabolic Disease
Brain Network Connectivity of Patients With Metabolic Diseases
The global prevalence of metabolic diseases, including hypertension, type 2 T2DM mellitus (T2DM), gout and obesity, has risen over the past two decades. Brain controls human behavior and metabolism in organisms.
- Trial name
- NCT06725589
- Testing
- metabolic disease
- Where
- China
- Volunteers
- 690 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Adhd
Psychostimulants Effects on Brain Functional Connectivity in Youth With Attention Deficit Hyperactivity Disorder
In the current study, we will administer three widely administered cognitive tasks while simultaneously measuring electroencephalography (EEG) in ADHD patients before and after methylphenidate immediate release (IR) treatment…
- Trial name
- NCT02318017
- Testing
- Methylphenidate
- Where
- Israel
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Healthy Participants
Combined Regulatory Effects of 40 Hz eTNS and Multisensory Stimulation on Brain Networks
The purpose of this study is to investigate the independent and interactive effects of 40Hz auditory, visual, and external trigeminal nerve stimulation (eTNS) on brain state dynamics and functional connectivity.
- Trial name
- NCT07668167
- Testing
- 40 Hz External Trigeminal Nerve Stimulation, 40 Hz Auditory Stimulation, 40 Hz Visual Stimulation
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Xidian University
Movement Disorder, Focal Dystonia
Movement-Related Brain Networks Involved in Hand Dystonia
This study will use various methods to measure the activity of the motor cortex (the part of the brain that controls movements) in order to learn more about focal hand dystonia.
- Trial name
- NCT00137384
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Pediatric Obesity, Behavior and Behavior Mechanisms
Neuro-cognitive Impact of Juvenile Obesity
Recent studies indicate that obese teenagers exhibit memory disturbances. Adolescence represents a crucial period in the development of the hippocampus and the amygdala, necessary for the implementation of memory and emotional…
- Conditions
- Pediatric Obesity, Behavior and Behavior Mechanisms, Emotions
- Trial name
- OBETEEN (NCT03776513)
- Testing
- an MRI examination
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux