Clinical trials: Brain Plasticity
Stroke With Hemiparesis
Transfer of Grasp Control Across Hands After Stroke
The purpose of this study is to examine if the strong hand can assist in the recovery of muscle function in the weak hand after a stroke.
- Trial name
- NCT00589368
- Testing
- Transfer of grasp control across hands
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Healthy Young Adult, Neurophysiology
Motor Cortex Plasticity Response to Theta-Burst Stimulation After Ketone Monoester Supplementation
Transcranial magnetic stimulation is a medical device that can alter motor cortical (M1) excitability through the scalp via various protocols.
- Trial name
- KME-TBS (NCT06799260)
- Testing
- Ketone Monoester (KME), iTBS, cTBS
- Where
- Malaysia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Healthy
Brain Maturation and Sleep
In this study, the investigator evaluates whether there are age-specific diurnal changes in markers of cortical plasticity in children, adolescents and adults.
- Trial name
- BMS (NCT02685891)
- Testing
- Playing tones during deep sleep
- Where
- Switzerland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Other Conditions of Brain
Roflumilast and TMS Motor Plasticity
Repetitive transcranial magnetic stimulation (rTMS) uses a magnetic field to non-invasively induce electrical function within the brain.
- Trial name
- NCT06457191
- Testing
- Roflumilast, Intermittent theta-burst stimulation transcranial magnetic stimulation, Continuous theta-burst stimulation transcranial magnetic stimulation
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Parenting, Child Development
Evaluating a Strengths-based Community-grounded Intervention
Structural inequities and historical underinvestment in marginalized communities create developmental contexts that constrain access to high-quality education, healthcare, stable housing, and other critical resources.
- Conditions
- Parenting, Child Development, Brain Development, Household and Family
- Trial name
- NCT06701240
- Testing
- ParentChild+, FamilyNutrition+
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Stroke, Ischemic, Healthy
Stochastic Resonance Stimulation in Brain Plasticity and Post Stroke Motor Recovery
This study evaluates the effectiveness of stochastic resonance electric stimulation on neuromuscular control and proprioception in healthy and individuals with stroke.
- Trial name
- NCT03839810
- Testing
- stochastic resonance electrical stimulation
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Spinal Cord Diseases
Reorganization of Brain Functions in Patients With Cervical Myelopathy Using fMRI and MRS
Decompressive surgery to relieve symptoms of spinal cord compression due to dysfunction, such as arthritis, has proved variable in success.
- Trial name
- NCT00447343
- Testing
- Decompressive cervical spine surgery, fMRI and MRS scan
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Suicide, Attempted, Suicide, Ideation
Teen Brain Training (TBT)
A non invasive treatment study including participants at risk for suicide attempts and undergoing neurofeedback training. Neurofeedback is controlling your brain activity in real time inside the scanner.
- Conditions
- Suicide, Attempted, Suicide, Ideation, Depression
- Trial name
- NCT06183580
- Testing
- neurofeedback training involving dACC, neurofeedback training involving amygdala
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Autism Spectrum Disorder
Investigation of Brain Plasticity in Autism Spectrum Disorders
Individuals with autism spectrum disorders (ASD) commonly experience variances in tactile behaviors, such as hypersensitivity to light touch stimuli, altered texture discrimination, and hyporesponsivity to pain.
- Trial name
- NCT04706364
- Testing
- Neuropsychological Testing, (Optional) Saliva Collection, Sensory Testing
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Parkinson Disease
Exercise and Plasticity in Parkinson Disease
We will study the effects of intensive rehabilitation in PD on plasticity with a multimodal approach. We will define first, whether exercise in PD restores the potentiation of the motor cortex to normal levels with both 5 Hz-rTMS…
- Trial name
- NCT05786261
- Testing
- experimental group MIRT, EEG task rTMS, fMRI
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo