Clinical trials: Brain Stroke
Ischemic Stroke, Carotid Artery Disease
Norwegian Carotid Plaque Study
BACKGROUND: In 30-40% the cause of ischemic stroke remains undetermined. Most likely, this category hides an additional number of strokes caused by artery-to-artery embolisms due to unidentified atherosclerotic disease, or caused…
- Conditions
- Ischemic Stroke, Carotid Artery Disease, Embolic Stroke
- Trial name
- NOR-PLAQ (NCT02759653)
- Where
- Norway
- Volunteers
- 16 people
- Sponsor
- Haukeland University Hospital
Stroke, Acute, Thrombolytic Therapy
Thrombolysis Outcome in Ischemic Stroke
Consecutive patients with diagnosis of acute ischemic stroke and candidate of thrombolytic therapy during Jan 2017-Mar 2019 in BuAli Sina Hospital ,Sari, Iran, enrolled to this cohort study.
- Conditions
- Stroke, Acute, Thrombolytic Therapy, Alteplase, Mortality
- Trial name
- TOSSI (NCT04309357)
- Testing
- Alteplase
- Where
- Iran
- Volunteers
- 214 people
- Sponsor
- Mazandaran University of Medical Sciences
Acute Ischemic Stroke
Efficacy and Safety of Mildronate for Acute Ischemic Stroke
This study seeks to evaluate the efficacy and safety of mildronate injection in treating acute ischemic stroke
- Trial name
- NCT01800357
- Testing
- infusion of mildronate, aspirin
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Xijing Hospital
Stroke
Nursing Home Care Intervention Post Stroke
Associated with the worsening of functional capacity of older adult and the lack of guidance on how to care of them after stroke, the family caregiver starts to fell burden related to the care, and the quality of life was…
- Trial name
- SHARE (NCT02807012)
- Testing
- Nursing educational intervention
- Where
- Brazil
- Volunteers
- 82 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Stroke, Adherence, Patient
iADAPT to Support Strategy Training After Stroke
Adherence to rehabilitation interventions is associated with functional outcomes (e.g. independence in daily activities, return of motor function) after stroke.
- Conditions
- Stroke, Adherence, Patient, Strategy Training
- Trial name
- NCT03253601
- Testing
- Strategy Training
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Pittsburgh
Intracranial Vascular Disorders
Mechanisms of Early Recurrence in Intracranial Atherosclerotic Disease
The objective of this study is to determine the mechanisms of stroke in patients with Intracranial Atherosclerotic Disease (IAD) by specifically evaluating limitations of antegrade flow through the stenotic artery, distal tissue…
- Trial name
- MyRIAD (NCT02121028)
- Where
- 10 sites in United States
- Volunteers
- 105 people
- Sponsor
- University of Miami
Unilateral Spatial Neglect, Stroke
Comparing Prism Adaptation Training With and Without TENS to Minimize Unilateral Spatial Neglect
This study aims to find out if doing two treatments together-Prism Adaptation Therapy (PAT) and Transcutaneous Electrical Nerve Stimulation (TENS)-will help people who have had a stroke pay better attention to one side of their…
- Trial name
- NCT07157865
- Testing
- Prism adaptation training combined with TENS, PAT only
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Kettering Health Network
Intracerebral Hemorrhage, Stroke
Tranexamic Acid for Acute ICH Growth prEdicted by Spot Sign
The purpose of this study is to determine if computed tomography angiography can predict which individuals with intracerebral hemorrhage will experience significant growth in the size of the hemorrhage.
- Trial name
- TRAIGE (NCT02625948)
- Testing
- Tranexamic Acid
- Where
- 11 sites in China
- Volunteers
- 240 people
- Sponsor
- Ministry of Science and Technology of the People´s Republic of China
Ischemic Stroke
Atherogenic Lipoproteins in Ischemic Stroke
Apolipoprotein B (apoB) levels (which encompass all atherogenic lipoproteins, including LDL), Lp(a) levels, and carotid IPH are associated with both first-ever and recurrent ischemic stroke.
- Trial name
- AGELESS (NCT05090878)
- Where
- 2 sites in Switzerland
- Volunteers
- 500 people
- Sponsor
- University Hospital, Basel, Switzerland
Stroke, Acute
Stent Retriever Versus Contact Aspiration in Irregular Occlusion Phenotype
Patients with a clinico-neuroradiological mismatch pattern shown on the magnetic resonance imaging/Computed Tomography in the acute phase of stroke are more likely to benefit from reperfusion, are suitable candidates for…
- Trial name
- STRIPE (NCT05595876)
- Testing
- stent retriever thrombectomy, contact aspiration thrombectomy
- Where
- 9 sites in France
- Volunteers
- 356 people
- Sponsor
- Hopital Foch
Periodontal Diseases, Saliva Altered
The Role of Periodontal Diseases and Stimulation of Saliva Secretion in the Acute Phase of Ischemic Stroke
Methods: 100 consecutive patients with their first ever ischemic stroke were enrolled in the study. 56 randomly selected patients were subjected to stimulation of salivation, the remaining patients were not stimulated.
- Conditions
- Periodontal Diseases, Saliva Altered, Stroke
- Trial name
- NCT05394090
- Testing
- saliva stimulation
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Stroke
Stimulating Language in Subacute StrokE
The investigators will study the effects of transcranial direct current (tDCS) stimulation during language therapy for naming in individuals with aphasia in the acute and subacute post stroke period.
- Trial name
- SLISSE (NCT02674490)
- Testing
- A-tDCS (1 mA), SALT
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Johns Hopkins University
Cryptogenic Symptomatic Transient Ischemic Attack, Cryptogenic Ischemic Stroke
Study of Continuous Cardiac Monitoring to Assess Atrial Fibrillation After Cryptogenic Stroke
The 2006 American Heart Association / American Stroke Association Council on Stroke Guidelines for Prevention of Stroke in Patients With Ischemic Stroke or Transient Ischemic recommended that patients with cryptogenic stroke take…
- Trial name
- CRYSTAL-AF (NCT00924638)
- Testing
- Reveal® XT Insertable Cardiac Monitor
- Where
- 55 sites in United States, Austria and 12 more
- Volunteers
- 447 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Stroke
Effectiveness of a Standardized Stroke Upper Limb Rehabilitation Program with Shortened Fugl-Meyer Assessment Stratification
The objective of the study was to investigate the effectiveness of a standardized stroke upper limb rehabilitation program with stratification using Shortened Fugl-Meyer Assessment (S-FM).
- Trial name
- NCT06902948
- Testing
- upper limb function training
- Where
- Hong Kong
- Volunteers
- 44 people
- Sponsor
- Sally Hiu Lam Wong
Stroke, Spatial Neglect
Validation of Web-Based Star Cancellation and Line Bisection Tests in Hemiplegic Stroke
The goal of this observational study is to evaluate the clinical usability and diagnostic performance of newly developed web-based Star Cancellation and Line Bisection tests in assessing visuospatial neglect in hemiplegic stroke…
- Conditions
- Stroke, Spatial Neglect, Spatial Neglect After Stroke
- Trial name
- NCT07538076
- Testing
- Web-Based Star Cancellation Test, Web-Based Line Bisection Test
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Stroke Rehabilitation
Vibratory Perturbation-based Pinch Task Training for Stroke Patients
The investigator assumed that perturbed-event-induced vibrotactile cueing enable more precision arm movement adjustment, sensory function and dexterity improvement in the spastic arm.
- Trial name
- NCT03798340
- Testing
- Vibratory perturbed task-specific movement training, Traditional task-oriented facilitation, Sensorimotor training
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Ischemic Stroke
"Hemodynamic Changes During Endovascular Revascularization for Acute Stroke. An Observational Study".
Neurocardiology is an emerging specialty that addresses the interaction between the brain and the heart, i.e. the effects of cardiac injury on the brain, and the effects of brain injury on the heart.
- Trial name
- NCT04771468
- Testing
- MOSTCAREup Monitoring, Ecocardiography
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Humanitas Clinical and Research Center
Stroke
Comparison of TTE and LTTBT on Trunk Control, Balance and ADL's in Stroke Patients
To compare the effects of trunk training exercises and lateral truncal tilt balance training on trunk control, balance and activities of daily living in stroke patients.The primary outcome measures used to evaluate the efficacy…
- Trial name
- NCT07248618
- Testing
- Trunk Training Exercises, Lateral Truncal Tilt Balance Training
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Ischemic Stroke
Clopidogrel Response and CYP2C19 Genotype in Ischemic Stroke Patients
Personalized therapy as prophylaxis in ischemic stroke patients is not yet an option. From patients with ischemic heart disease, we know that patients with in vitro high on treatment platelet reactivity (HTPR) have an increased…
- Trial name
- CLOGIS (NCT03385538)
- Testing
- Clopidogrel
- Where
- Denmark
- Volunteers
- 103 people
- Sponsor
- Zealand University Hospital
Stroke
Impact of Training on Gait and Strength in Stroke Survivors
Background: A discrepancy between strength gain and gait changes following various training programs aimed at improving gait function after stroke has been noted.
- Trial name
- NCT01818349
- Testing
- isokinetic lower-limb training, isokinetic upper-limb training
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Université de Montréal
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