Clinical trials: Brain Stroke
Ischemic Stroke, Anesthesia
The Effect of Sedoanalgesia and General Anaesthesia on Early Neurological Recovery in Acute Ischaemic Stroke Patients Undergoing Endovascular Thrombectomy
The hypothesis of this study is that sedoanalgesia will provide better early neurological recovery than general anaesthesia in acute ischaemic stroke patients undergoing endovascular thrombectomy and to investigate the…
- Conditions
- Ischemic Stroke, Anesthesia, Neurologic Symptoms
- Trial name
- NCT06183567
- Testing
- Sedoanalgesia, general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Umraniye Education and Research Hospital
Stroke
Pre-stroke Physical Activity in Patients With Stroke
The aim of this study is to explore the level of pre-stroke physical activity in patients with stroke and to investigate associations between physical activity and sociodemographic variables, e.g.
- Trial name
- NCT05051111
- Where
- Denmark
- Volunteers
- 123 people
- Sponsor
- Herlev Hospital
Intensive Care Unit (ICU) Acquired Weakness (ICU - AW), Acquired Brain Injury (Including Stroke)
Functional Electrical Stimulation to Treat Critical Neuromyopathy After Severe Stroke: a Pilot Study.
This study aims to evaluate the effectiveness of physiotherapy treatment combined with functional electrical stimulation (FES) in a small group of patients with severe acquired brain injury (SABI) of vascular origin and with a…
- Trial name
- RISE (NCT07130929)
- Testing
- Functional Electrical Stimulation, Conventional physiotherapy
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Ischemic Stroke, Acute
Shuxuening Injection in the Treatment With Intravenous Thrombolysis in Patients With Ischemic Stroke (SHINY)
Shuxuening injection is a multi-target neuroprotective agent, it is expected to play a neuroprotective role on the basis of intravenous thrombolysis therapy.
- Trial name
- NCT06157502
- Testing
- Shuxuening Injection
- Where
- 82 sites in China
- Volunteers
- 1,380 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Ischemic
Improving Neurological Outcome for Acute Basilar Artery Occlusion With Sufficient Recanalization After Thrombectomy by Intraarterial Tenecteplase (INSIST-IT)
The potential benefit of intraarterial tenecteplase in acute basilar artery occlusion (BAO) patients with successful reperfusion following endovascular treatment (EVT) has not been studied.
- Trial name
- NCT05657457
- Testing
- Tenecteplase
- Where
- China
- Volunteers
- 145 people
- Sponsor
- General Hospital of Shenyang Military Region
Stroke, Acute
F.A.S.T.-BE FAST Stroke Warning Signs Study
The goal of this randomized controlled trial is to learn whether the BE FAST (Balance, Eyes, Face, Arm, Speech, and Time) acronym works at least as well or better than the F.A.S.T.
- Trial name
- NCT06483165
- Testing
- BE FAST Educational video, F.A.S.T. Educational Video
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- American Heart Association
Healthy Volunteer
Spaced Versus Massed Skill Learning
This study will explore the optimum training schedule for stroke patients to learn motor skills. It will see if motor training is more effective when training sessions are distributed over time (spaced training) or when the…
- Trial name
- NCT00426465
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke
Multifunctional Nutrition Tube on Social Condition and Experience in Cerebralvascular Accident
The aim of this clinical trial is to compare the psychological condition and experience of ischemic stroke patients who receive enteral nutrition support through either Intermittent Oro-esophageal Tube or Nasogastric Tube.
- Trial name
- NCT06328907
- Testing
- comprehensive rehabilitation therapy, Intermittent Oro-esophageal Tube Feeding, Nasogastric Tube Feeding
- Volunteers
- 80 people
- Sponsor
- Copka Sonpashan
Stroke
Effect of Pelvic Stability Training on Lower Limb Motor Function in Subacute Stroke
A stroke occurs when blood stops flowing through a blood vessel to the brain, typically from a burst blood vessel or a blood clot.
- Trial name
- NCT07609407
- Testing
- baseline treatment neuromuscular electrical stimulation and stretching exercises for lower limb and Pelvic Stability Training, Neuromuscular electrical stimulation and lower limb passive stretching
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- University of Faisalabad
Stroke
Gait Speeds and Demands in Chronic Stroke Patients: A Multi-dimensional Investigation
This study investigated the effect of treadmill walking training with and without random speed changes in persons in the chronic stage of stroke.
- Trial name
- NCT04436536
- Testing
- Treadmill walking training with random speed changes, Treadmill walking training with blocked speed changes
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Cheng Kung University
Chronic Kidney Disease, Acute Bleeding
The Strategy to Prevent Hemorrhage Associated With Anticoagulation in Renal Disease Management (STOP HARM) Trial
Patients with severe chronic kidney disease (CKD) who develop atrial fibrillation are at high risk for stroke. The use of blood thinking medication in dialysis patients is controversial and warfarin carries a serious risk for…
- Conditions
- Chronic Kidney Disease, Acute Bleeding, Cerebrovascular Stroke
- Trial name
- STOP-HARM (NCT02885545)
- Testing
- Watchman, Continued therapy with the prescribed oral anticoagulant
- Where
- Canada
- Sponsor
- Population Health Research Institute
Stroke, Lacunar
Effect of Remote Ischemic Conditioning on Vascular Health in Stroke Patients
The main aim of the current study is to assess cardiovascular effects of remote ischemic conditioning in patients who have suffered from stroke.
- Trial name
- VISP (NCT03635177)
- Testing
- Remote ischemic conditioning
- Where
- 2 sites in Denmark
- Volunteers
- 30 people
- Sponsor
- University of Copenhagen
Stroke
REINVENT: A Brain and Muscle Computer Interface for Stroke
Stroke is a leading cause of adult disability in the United States. High doses of repeated task-specific practice have shown promising results in restoring upper limb function in chronic stroke (>6 months after onset).
- Trial name
- REINVENT (NCT06285175)
- Testing
- Tele-REINVENT
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Southern California
Stroke, Ischemic
Regional Strategy for Transfer for Mechanical Thrombectomy
A mono-centre observational study with the aim of compare clinical outcome at 3 month on patients admitted with recent cerebral infarct and intracranial large vessel occlusion in the anterior circulation who are eligible for…
- Conditions
- Stroke, Ischemic, Large Vessel Occlusion
- Trial name
- START (NCT04046757)
- Testing
- Mechanical thrombectomy
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- University Hospital, Montpellier
Stroke, Ischemia
A Safety and Tolerability Study of 42037788 (Referred to as CNTO 0007) Compared With Placebo in Patients Who Have Experienced Ischemic Cerebral Infarction (Also Known as Stroke)
The purpose of this study is to evaluate the safety and tolerability of 42037788 (CNTO 0007) in patients who have suffered a stroke.
- Conditions
- Stroke, Ischemia, Infarction
- Trial name
- NCT01273467
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Janssen Research & Development, LLC
Sickle Cell Anemia in Children
Stroke Prevention With Hydroxyurea Enabled Through Research and Education (SPHERE)
This study will 1) Evaluate the prevalence of elevated (conditional or abnormal) transcranial Doppler (TCD) velocities in a cross-sectional analysis of children with Sickle Cell Anemia (SCA) living in Tanzania; 2) Obtain…
- Trial name
- NCT03948867
- Testing
- Hydroxyurea, Elevated Arm TCD Examination, Normal Arm TCD Examination
- Where
- 2 sites in United States, Tanzania
- Volunteers
- 202 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Ischemic Stroke
The Efficacy of a Frequency-tuned Electromagnetic Field Treatment in Facilitating the Recovery of Subacute Ischemic Stroke Patients - a Pivotal Study (THE "EMAGINE" STUDY)
This is a multicenter study that will be conducted at approximately 20 centers. BQ 2.0 is a wearable medical device that produces and delivers non-invasive, extremely-low-intensity and low-frequency, frequency-tuned…
- Trial name
- BQ5 (NCT05044507)
- Testing
- BQ 2.0
- Where
- 15 sites in United States
- Volunteers
- 100 people
- Sponsor
- BrainQ Technologies Ltd.
Stroke
Sit-to-stand Training in Stroke Patient
Background: It is unknown whether the self-initiated sit-to-stand training with assistive device is effective to regain the independence of sit-to-stand in stroke patients.
- Trial name
- NCT03273101
- Testing
- Mechanical assisted sit-to-stand training group, Manual assisted sit-to-stand training group
- Volunteers
- 52 people
- Sponsor
- Tai Po Hospital
Acute Ischemic Stroke
SELECT2: A Randomized Controlled Trial to Optimize Patient's Selection for Endovascular Treatment in Acute Ischemic Stroke
SELECT 2 evaluates the efficacy and safety of endovascular thrombectomy compared to medical management alone in acute ischemic stroke patients due to a large vessel occlusion in the distal ICA and MCA M1 who have large core on…
- Trial name
- SELECT2 (NCT03876457)
- Testing
- Endovascular Thrombectomy, Medical Management
- Where
- 31 sites in United States, Australia and 4 more
- Volunteers
- 352 people
- Sponsor
- University Hospitals Cleveland Medical Center
Cognitive Impairment, Stroke
SMARTease Trial: Evaluating Stroke Help Distance Interventions to Improve Cognitive Performance Post-Stroke
The purpose of this study is to provide evidence for the feasibility and initial effectiveness of a manualized, telephone-based (telehealth) approach to the delivery of cognitive interventions (SMARTease) targeted to improve…
- Trial name
- SMARTease (NCT01407081)
- Testing
- Telerehabilitation Cognitive Strategy Training
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- Nova Scotia Health Authority
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