Clinical trials: Brain Stroke
Stroke
Clinical Effects of Peroneal Nerve Functional Electrical Stimulation (WalkAide[R]) for Chronic Stroke Patients
RATIONALE: The previous study resulted that the gait training using Functional Electrical Stimulation (FES) improved the ankle joint function and the walking ability for the chronic stroke patients with foot drop.
- Trial name
- PLEASURE (NCT02897752)
- Testing
- gait training with WA, usual gait training
- Where
- 24 sites in Japan
- Volunteers
- 120 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Acute Ischemic Stroke
TWIN2WIN (Double Stent (DS-EVT) Versus Primary Thrombectomy With One Stent (SS-EVT))
The use of a double stent retriever (Dual-SR) has been proposed as a safe and effective technique. The invesigators hypothesized that the use of Dual-SR primary could lead to higher first-pass effect rates and better outcomes…
- Trial name
- NCT05632458
- Testing
- Thrombectomy
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Ischemic Stroke
Study of Tenecteplase Versus Alteplase for Thrombolysis (Clot Dissolving) in Acute Ischemic Stroke
BACKGROUND: Alteplase dissolves blood vessel clots in acute ischemic stroke and is the only approved acute drug treatment <4½ hours of stroke onset.
- Trial name
- NOR-TEST (NCT01949948)
- Testing
- Tenecteplase, Alteplase
- Where
- 13 sites in Norway
- Volunteers
- 1,050 people
- Sponsor
- Lars Thomassen
Ischemic Stroke
Intravenous Thrombolysis Registry for Acute Ischemic Stroke in China
To analyze the real situation of intravenous thrombolysis in acute ischemic stroke in China
- Trial name
- NCT03997292
- Testing
- Alteplase, Urokinase
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- General Hospital of Shenyang Military Region
Stroke
Applicability of Techniques of Lung Expansion
The survival of patients with lesions in the central nervous system is usually accompanied by physical and mental sequelae. These impairments favor the prolonged restriction to the bed, which may contribute with changes in…
- Trial name
- NCT02613832
- Testing
- EPAP, Breath Stacking
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Transient Ischemic Attack, Minor Ischemic Stroke
Dabigatran Following Transient Ischemic Attack and Minor Stroke
Rationale: To date, anticoagulant therapy in acute stroke has also been limited by excess hemorrhagic events. The oral anticoagulant dabigatran is a novel agent, which has been shown to be associated with much lower intracranial…
- Trial name
- DATAS II (NCT02295826)
- Testing
- Dabigatran, Acetylsalicylic acid
- Where
- 6 sites in Canada
- Volunteers
- 300 people
- Sponsor
- University of Alberta
Stroke Hemorrhagic
DTI-guided Minimally Invasive Hematoma Evacuation for Intracerebral Hemorrhage
Intracerebral hemorrhage (ICH) is a devastating disease with high early mortality, unfavorable neurological outcomes, and high cost of care.
- Trial name
- GLAMOR (NCT05891509)
- Testing
- Minimally Invasive Hematoma Evacuation, Best Medical Therapy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhongming Qiu
Acute Ischemic Stroke
Intra-arterial Albumin in Acute Ischemic Stroke After Endovascular Treatment for
Stroke is an acute focal injury of the central nervous system caused by cerebral vessels. One in every four people is affected by stroke at different times in life.
- Trial name
- NCT06172387
- Testing
- intra-arterial infusion albumin, mechanical thrombectomy and a standard clinical therapy
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Tianjin Huanhu Hospital
Cerebral Infarction
Multi-modality MRI Study on Effect to Collateral Circulation and Blood Perfusion of Acute Cerebral Infarction by Human Urinary Kallidinogenase
Human urinary kallidinogenase can promote the establishment of collateral circulation in the ischemic penumbra due to the stenosis or occlusion of middle cerebral artery and then increase the perfusion.
- Trial name
- NCT02259738
- Testing
- Human Urinary Kallidinogenase, Shuxuening injection
- Where
- China
- Volunteers
- 120 people
- Sponsor
- XuanwuH 2
Stroke, Hemiplegia
Asymmetrical Gait Training After Pediatric Stroke
The purposes of this pilot research study are 1. To begin to test if two different types of physical therapy might have different results in children and adolescents who have had a prior stroke, and 2.
- Trial name
- NCT01827436
- Testing
- Conventional physical therapy, Asymmetrical gait training
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Children's Hospital of Philadelphia
Ischemic Stroke
Stroke Registration of Young Adults in China
This is a multi-center, prospective,continuous registry study. The investigators will include 3000 young adult (18-45 years old) patients with confirmed first-ever acute ischemic stroke in China.
- Trial name
- REACH (NCT03024164)
- Testing
- Treatment following current guidelines
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Yi Yang
Strokes Thrombotic
Patient Education Program and Trunk Control Exercises in Post-stroke
The trunk movement awareness and education of individuals with post-stroke hemiparesis is not emphasized adequately in clinical practice.
- Trial name
- NCT06679699
- Testing
- Trunk control exercises combined with patient education program, Trunk control exercises
- Where
- United Arab Emirates
- Volunteers
- 40 people
- Sponsor
- Gulf Medical University
Stroke, Stroke, Acute
Visio-conference for Pre-hospital Triage of Stroke Suspicions
Interventionnal Study to investigate the accuracy of our clinical based algorithm performed by using a visioconference device to assess the eligibility of acute recanalisation treatment (intraveinous thrombolysis (IVT) and/or…
- Conditions
- Stroke, Stroke, Acute, Stroke, Ischemic, Cerebrovascular Disorders
- Trial name
- OPTIC-AVC (NCT04042584)
- Testing
- Visio conference device evaluation (DVCM)
- Where
- France
- Volunteers
- 215 people
- Sponsor
- University Hospital, Bordeaux
Cranial Diseases (e.g., Brain Tumors, Stroke, Neurodegenerative Disorders)
Construction of AI Model for Precision Imaging Diagnosis of Cranial Diseases
The goal of this observational study is to develop and validate a high-precision AI diagnostic model for cranial diseases by integrating clinical knowledge systems (pathophysiological classification, age stratification, and…
- Trial name
- NCT07446842
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Sub-acute Stroke
Using Immersive Virtual Reality for the Upper Limb Rehabilitation of Post-stroke Subjects
Stroke produces brain damages that results in sensory, motor, and cognitive impairments which reduce the patient's quality of life and social participation.
- Trial name
- NCT06892886
- Testing
- Virtual Reality
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- University Hospital of Ferrara
Parkinson's Disease, Stroke
Training With Exergame and Treadmill on Executive Function and Dual-task Performance
This study aimed to investigate the effects of dual-task training with exergame and treadmill on executive function and dual-task performance in individuals with PD and stroke and discuss the correlation between the change values…
- Trial name
- NCT03623841
- Testing
- Dual-task training, Treadmill training
- Where
- Taiwan
- Volunteers
- 28 people
- Sponsor
- National Yang Ming Chiao Tung University
Postoperative Delirium, Postoperative Stroke
Impact of Personalised Cardiac Anaesthesia and Cerebral Autoregulation on Neurological Outcomes in Patients Undergoing Cardiac Surgery
This international, multicentre prospective cohort study will assess whether perioperative duration and magnitude of mean arterial pressure (MAP) outside of an individual's cerebral autoregulation (CA) limits using near-infrared…
- Conditions
- Postoperative Delirium, Postoperative Stroke, Postoperative Cognitive Dysfunction
- Trial name
- PRECISION (NCT05595954)
- Testing
- Preoperative data collection, Intraoperative NIRS, Intraoperative TCD
- Where
- 4 sites in Switzerland, United Kingdom
- Volunteers
- 500 people
- Sponsor
- University Hospital, Basel, Switzerland
Acute Ischemic Stroke, Cerebral Infarction
Safely Quenching Complement in Stroke Survivors
This study will include adults (ages 18-80) who have had a stroke caused by a large blood clot blocking blood flow in the brain.
- Trial name
- SUCCESS (NCT07495722)
- Testing
- Pegcetacoplan Injection [Empaveli]
- Volunteers
- 20 people
- Sponsor
- Columbia University
Stroke, Peripheral Neuropathy
Arm Motor Control on Bi and Uni ADLs
This study is being performed to assess how certain chronic disabilities - stroke, upper extremity (UE) amputation, spinal cord injuries (SCI), cerebral palsy (CP) - differ from healthy subjects in their ability to perform ADLs.
- Conditions
- Stroke, Peripheral Neuropathy, Spinal Cord Injuries, Cerebral Palsy
- Trial name
- BiAs (NCT02778529)
- Testing
- Bilateral assessment robots (BiAS)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Dysphagia, Aspiration
Effect of Afferent Oropharyngeal Pharmacological and Electrical Stimulation on Swallow Response and on Activation of Human Cortex in Stroke Patients With Oropharyngeal Dysphagia
Oropharyngeal dysphagia (OD) is a major complaint among many patients with stroke and causes severe complications. There is no specific treatment for these patients.
- Conditions
- Dysphagia, Aspiration, Stroke
- Trial name
- NCT01777672
- Testing
- Dietary and oral hygiene recommendations, oral TRPV1 agonist, pharyngeal electrical stimulation
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital de Mataró
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