Clinical trials: Brain Stroke
Stroke, Parkinson Disease
Videofluoroscopic Swallowing Study (VFSS)
The study procedure of simultaneous VFSS and DDS measurement will be completed in one day and the subject will be followed within 2 business days after the study procedure to monitor for adverse events.
- Conditions
- Stroke, Parkinson Disease, Multiple Sclerosis, Oropharyngeal Dysphagia
- Trial name
- PORSCHE (NCT03387267)
- Testing
- Dysphagia Detection System
- Where
- 13 sites in United States, Finland
- Volunteers
- 452 people
- Sponsor
- Société des Produits Nestlé (SPN)
TIA, Ischemic Stroke
Sleep Disordered Breathing in Transient Ischemic Attack (TIA)/Ischemic Stroke and Continuous Positive Airway Pressure (CPAP) Treatment Efficacy
The study aims to observe the short term effect (3-month) of sleep disordered breathing (SDB) on cardiovascular parameters, heart rate variability, endothelial function and surrogate markers of atherosclerosis after acute…
- Trial name
- SAS-CARE (NCT01097967)
- Testing
- CPAP
- Where
- 5 sites in Germany, Italy and 1 more
- Volunteers
- 246 people
- Sponsor
- Prof. Claudio Bassetti
Stroke
EvolvRehab for Telerehabilitation
This study includes two stages to develop the use of EvolvRehab telerehabilitation in the use of Stroke patients, early after stroke. All tasks will be conducted by multiple research sites.
- Trial name
- NCT05875792
- Testing
- EvolvRehab - MoveWell
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Exeter
Stroke
Repetitive Transcranial Magnetic Stimulation (rTMS) to Promote Hand Recovery in Stroke
Paralysis following stroke stems not only from the loss of neurons killed by the stroke but also from the loss of neurons lying dormant in the stroke hemisphere.
- Trial name
- rTMS (NCT00913211)
- Testing
- rTMS, Motor learning training, rTMS and Tracking
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Minnesota
Stroke, Acute, Angiography
Comparison Between TOF and SWAN Sequences in the Detection of Arterial Occlusion in Acute Ischemic Stroke Using MRI
Optimizing the MRI protocol in acute ischemic stroke remains a challenging issue. In this field, susceptibility-weighted sequences have proved their superiority over T2.
- Conditions
- Stroke, Acute, Angiography, Magnetic Resonance Imaging, Diagnosis
- Trial name
- TOF-SWAN (NCT03645902)
- Testing
- Magnetic resonance imaging
- Volunteers
- 34 people
- Sponsor
- Lille Catholic University
Stroke
Comparative Effects of Dual Task and PNF on Balance ,Cognition and Motor Function in Chronic Stroke Patients .
The aim of this study is to compare the effect of dual tasking and proprioceptive neuromuscular facilitation on balance, cognition and motor function in chronic stroke patients. It will be randomized clinical trial.
- Trial name
- NCT05931172
- Testing
- Dual tasking, PNF(proprioceptive neuromuscular facilitation exercises)
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Coronary Heart Disease and Stroke
A Comparison of the Estimates of Fuwai and Reynolds Risk Model
There are many risk prediction models. And their estimates are different. This study aimed to investigate the differences between the estimates of Fuwai and Reynolds risk model in Chinese, and investigate the reason for the…
- Trial name
- NCT02241239
- Where
- 2 sites in China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Wuhan Asia Heart Hospital
Stroke
Immediate Effects of Open and Closed Kinetic Chain Exercises on Upper Extremity in Stroke Patients.
Stroke is a sudden disruption of blood flow to the brain, resulting in physical and mental disabilities. It's a global health issue affecting millions each year, often leading to paralysis, altered muscle tone, and loss of motor…
- Trial name
- NCT06272175
- Testing
- Open Kinetic Chain Activity, Closed Kinetic Chain Activity
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istinye University
Intracerebral Hemorrhage
Recovery and Outcomes From Stroke
The investigators will perform follow-up on 500 cases of deep and lobar intracerebral hemorrhage to perform advanced neuroimaging before 45 days post stroke, and evaluations of motor and cognitive function at baseline, 3 months…
- Trial name
- ROSE (NCT04007757)
- Where
- 8 sites in United States
- Volunteers
- 500 people
- Sponsor
- State University of New York at Buffalo
Stroke
Motor and Neurophysiological Changes After Ischemic Conditioning in Individuals With Stroke
The goal of this clinical trial is to test ischemic conditioning (blood flow restriction) as a neuromodulatory technique to improve gait function in stroke.
- Trial name
- NCT05906602
- Testing
- Real Ischemic Conditioning
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Illinois Chicago
Transient Ischemic Attack, Stroke
Pilot Study of Continuing Aspirin Versus Switching to Clopidogrel After Stroke or Transient Ischemic Attack
Pilot study of continuing aspirin versus switching to clopidogrel after stroke or transient ischemic attack.
- Conditions
- Transient Ischemic Attack, Stroke, Aspirin, Clopidogrel
- Trial name
- NCT00363753
- Testing
- aspirin versus clopidogrel
- Where
- 2 sites in United States
- Sponsor
- University of California, San Diego
Stroke
Cortical Activity and Gait Function for Robotic Gait Training in Hemiparetic Stroke
Effects of robot-assisted gait training on cortical activity and gait function in hemiparetic stroke
- Trial name
- NCT04054739
- Testing
- Robot-assisted gait training, Treadmill gait training
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- National Rehabilitation Center, Seoul, Korea
Stroke, Medication Adherence
Adherence to Medical Treatments for Telemedicine Patients
This study will test the feasibility of MedRem, a novel medication reminder and tracking system on wearable wrist devices, specifically with the Apple Watch 4.
- Trial name
- NCT04180475
- Testing
- MedRem application
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Stroke, Ischemic Stroke
Robotic rEhabilitation sCenario fOr patieNts With NeglECT
The goal of this pilot clinical trial is to develop an integrated motor and cognitive rehabilitation program and evaluate the usability and acceptability of a new virtual reality scenario designed for the MOTORE device.
- Conditions
- Stroke, Ischemic Stroke, Haemorrhagic Stroke, Neglect, Hemispatial
- Trial name
- RECONNECT (NCT06890481)
- Testing
- Upper-limb planar robotic intervention
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Post-Stroke Cognitive Impairment (PSCI)
Electroacupuncture Treatment for Post-stroke Cognitive Impairment
Stroke is a global public health issue, and it has become a leading cause of death and disability in China. With the rapid aging of the Chinese population, its incidence rate is continuously rising.
- Trial name
- NCT07208019
- Testing
- Acupuncture
- Where
- 5 sites in China
- Volunteers
- 340 people
- Sponsor
- Ruijie Ma
Carotid Artery Diseases, Coronary Artery Disease
Outcome of LA Versus GA for Staged CEA Prior To CABG
A retrospective analysis of all patients that underwent carotid endarterectomy (CEA) for stenotic disease - diagnosed at pre-operative investigation - prior to CABG as staged operation within 6- months.
- Conditions
- Carotid Artery Diseases, Coronary Artery Disease, Stroke
- Trial name
- NCT04901000
- Testing
- Carotid endarterectomy
- Volunteers
- 44 people
- Sponsor
- Thomas Aherne
Stroke
Acute Stroke Thrombectomy: Does CT Perfusion Accurately Predict Infarct on MRI After Recanalization
The newest generation of stent---retrievers results in higher recanalization rates and faster recanalization time compared to older generation endovascular therapies for acute stroke.
- Trial name
- NCT02988492
- Testing
- MRI perfusion imaging
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Ottawa Hospital Research Institute
Stroke, Hemispatial Neglect
Guanfacine for the Treatment of Spatial Neglect and Impaired Vigilance
To find out if spatial neglect following stroke and brain injury can be reduced using guanfacine, a drug that was shown to improve neglect in two stroke patients in a previous pilot study (Malhotra et al, 2006).
- Trial name
- GASNIV (NCT00955253)
- Testing
- Guanfacine
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- Imperial College London
Cardiac Arrest, Sepsis
Improving Outcomes After Time Sensitive Prehospital Interventions: Rescu Epistry
Rescu Epistry includes data points pertaining to prehospital and in-hospital clinical treatments and responses to therapy, survival to discharge and functional outcome data for all cases.
- Conditions
- Cardiac Arrest, Sepsis, Trauma, Stroke
- Trial name
- NCT04110912
- Testing
- This is a registry and no interventions are taking place.
- Where
- 3 sites in Canada
- Sponsor
- Unity Health Toronto
Stroke
Group Lifestyle Balance™ for Individuals With Stroke (GLB-CVA)
The purpose of this RCT is to examine the efficacy of the Group Lifestyle Balance (GLB) program adapted for people with stroke (CVA) on primary (weight) and secondary outcomes at 3, 6, 12 months from enrollment into the program.
- Trial name
- GLB-CVA (NCT03873467)
- Testing
- Group Lifestyle Balance, Usual Care
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Baylor Research Institute
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