Clinical trials: Brain Stroke
Cerebral Vascular Disorder
Evaluation of Physical Activity Practice (AP) After Cerebral Vascular Stroke (Stroke)
Physical activity is defined by any movement produced by the skeletal muscles responsible for an increase in energy expenditure.
- Trial name
- QAP-AVC (NCT03689387)
- Testing
- the Medical Program Information Systems (PMSI)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Stroke
Tolerability of Enecadin (INN) in Acute Ischemic Stroke Trial - TEST
The main objective of this study is to investigate the tolerability of enecadin in patients with acute ischemic stroke. Furthermore, the pharmacokinetics of enecadin in both male and female patients with acute ischemic stroke…
- Trial name
- NCT00331721
- Testing
- Enecadin
- Where
- 26 sites in Austria, Belgium and 1 more
- Volunteers
- 24 people
- Sponsor
- PAION Deutschland GmbH
Stroke
REINVENT: A Brain and Muscle Computer Interface for Stroke
Stroke is a leading cause of adult disability in the United States. High doses of repeated task-specific practice have shown promising results in restoring upper limb function in chronic stroke (>6 months after onset).
- Trial name
- REINVENT (NCT06285175)
- Testing
- Tele-REINVENT
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Southern California
Subacute Stroke, Upper Limb
Additional Effects of Kinesio-Taping Along with Conservative Physical Therapy on Upper Limb Function, Range of Motion and Spasticity in the Patients with Subacute Stroke
A randomized control trial will be done on diagnosed stroke patients of subacute stage in Fauji Foundation Hospital Rawalpindi and leading edge physical therapy and rehabilitation clinic.The purpose of the study is to determine…
- Conditions
- Subacute Stroke, Upper Limb, Range of Motion, Spasticity
- Trial name
- NCT06674057
- Testing
- KinesioTaping, Control
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Foundation University Islamabad
Acute Ischemic Stroke
Long-term Outcome of RIPC After IV Thrombolysis in AIS Patients
The goal of this observational study is to learn about the long-term efficacy of our previous study in acute ischemic stroke(AIS) patients who underwent either remote ischemic postconditioning(RIPC) or sham treatment after…
- Trial name
- RESPONTH (NCT05614401)
- Testing
- functional and medical information
- Where
- China
- Volunteers
- 62 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Ischemic Stroke, Intracranial Hematoma
Investigation of Clot in Ischemic Stroke and Hematoma Evacuation
The aim of the study is to collect and analyze specimen from ischemic stroke patients undergoing thrombectomy procedures and from patients undergoing minimally invasive surgery for intracranial hematoma evacuation.
- Trial name
- INSIGHT (NCT04693767)
- Testing
- Mechanical thrombectomy, Minimally invasive surgery
- Where
- 27 sites in United States
- Volunteers
- 400 people
- Sponsor
- Penumbra Inc.
Stroke
Families In Recovery From Stroke Trial (F.I.R.S.T.)
The purpose of this trial is to assess the effects of a psychosocial intervention on functional recovery after stroke.
- Trial name
- NCT00037492
- Testing
- home-based sessions/family meetings with trained clinician
- Where
- 6 sites in United States
- Volunteers
- 291 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke, Dysphagia
Effect of Theta Burst Transcranial Magnetic Stimulation on Patients with Dysphagia After Stroke
The purpose of this study was to observe the effect of Theta burst transcranial magnetic stimulation (TBS) on swallowing function in patients with dysphagia after stroke (PSD).
- Conditions
- Stroke, Dysphagia, Functional Near- Infrared Spectroscopy, Transcranial Magnetic Stimulation
- Trial name
- NCT06471309
- Testing
- Theta burst transcranial magnetic stimulation
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Zhang Xiaohui
Cerebral Vascular Accident
New Protocols in the Treatment of Upper Limb Dysfunctions of Patients With Stroke.
The fundamental goals of early rehabilitation for patients with stroke are: optimizing motor function within each patient's prognostic potential, preventing the development of secondary conditions that impact life-long health…
- Trial name
- NCT01947413
- Testing
- intermittent theta burst stimulation, continuous theta burst stimulation
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Stroke, Inflammation
Combinating Fingolimod With Alteplase Bridging With Thrombectomy in Acute Ischemic Stroke
Proof-of concept clinical trials have indicated that the sphingosine-1-phosphate receptor modulator fingolimod may be efficacious in attenuating brain inflammation and improving clinical outcomes in patients with AIS as a single…
- Trial name
- NCT04675762
- Testing
- Fingolimod
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acute Ischemic Stroke
Phase III Clinical Trial of rhTNK-tPA in Treating Acute Ischemic Stroke With Extended Time Window.
This is a multicenter, randomized, double-blind, placebo-controlled Phase III clinical study designed to evaluate the efficacy of recombinant human tissue-type plasminogen activator variant (rhTNK-tPA) (0.25 mg/kg, maximum dose…
- Trial name
- TRACE-LATE (NCT07201688)
- Testing
- rhTNK-tPA
- Where
- China
- Volunteers
- 890 people
- Sponsor
- CSPC Mingfule Pharmaceutical (Guangzhou) Co., Ltd.
Ischemic Stroke, Hemorrhagic Stroke
Transcranial Direct Current Stimulation, Functional Activity, Stroke, RCT
Stroke patients often experience impaired balance and weight-bearing due to muscle weakness and neurological deficits. Motor rehabilitation is a crucial goal in their recovery, and transcranial direct current stimulation (tDCS)…
- Conditions
- Ischemic Stroke, Hemorrhagic Stroke, Stroke, Cardiovascular
- Trial name
- NCT07200661
- Testing
- Experimental A tDCS: Transcranial direct current stimulation., Experimental B tDCS: Transcranial direct current stimulation., Experimental C tDCS: Transcranial direct current stimulation.
- Where
- 3 sites in Thailand
- Volunteers
- 30 people
- Sponsor
- University of Phayao
Ischemic Stroke
Prevalence of Cerebral Large Vessel Occlusion Among Acute Ischemic Stroke Patients in Assiut University Hospitals
Prevalence of Large Vessel Occlusion among acute ischemic stroke patients in Assiut University hospitals 1. Study Objectives Primary Objective: To determine the prevalence of LVO among acute ischemic stroke (AIS) patients…
- Trial name
- NCT07326410
- Volunteers
- 300 people
- Sponsor
- Assiut University
Recovery Methods, Rehabilitation Program
A Randomized, Single-blind Trial of LI-TMS and AVS for Stoke Recovery in Healthy Participants (Phase 1).
This randomized, controlled, single-blind clinical pilot study investigates the therapeutic potential of low-intensity repetitive transcranial magnetic stimulation (LI-TMS) and audio-visual stimulation (AVS) and newly offered…
- Conditions
- Recovery Methods, Rehabilitation Program, Stroke, Ischemic, Stroke
- Trial name
- NCT06613282
- Testing
- Low Intensity Transcranial Magnetic Stimulation, Auditory and visual stimulation
- Where
- Russia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Siberian Scientific Research and Test Center for Biomedical Engineering
Cardioembolic Stroke
Dabigatran Study in the Early Phase of Stroke. New Neuroimaging Markers and Biomarkers Study (SEDMAN STUDY)
SEDMAN study is a prospective multicenter investigator initiated study (IIS). The main idea is to look by Genome Wide Association (arrays that determine more than 1 million polymorphisms) genetic risk factors associated with…
- Trial name
- SEDMAN (NCT02742480)
- Testing
- Dabigatran, Acenocoumarol
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Hospital Mutua de Terrassa
Stroke, Cerebral Vascular Accident (CVA)/Stroke
Error-enhanced Learning & Recovery in 2 & 3 Dimensions
This study is being done to see how errors lead to improvement. Specifically, we are evaluating the errors stroke participants make during an upper extremity exercise program when reaching for a target using their affected arm.
- Trial name
- NCT05180786
- Testing
- Error Fields, No Error Fields
- Where
- 3 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Stroke, Cardiovascular Death
A Prospective Multicenter Study to Evaluate Usefulness of Cardio-Ankle Vascular Index in Japan
The objective of this five-year prospective observational follow-up study is to examine the additional benefits of using cardio-ankle vascular index (CAVI) as a predictive indicator of cardiovascular events in high-risk patients.
- Conditions
- Stroke, Cardiovascular Death, Nonfatal Myocardial Infarction
- Trial name
- CAVI-J (NCT01859897)
- Where
- Japan
- Volunteers
- 3,026 people
- Sponsor
- CAVI-J Study Group
Stroke, Cardiovascular
Brain and Behavior Correlates of Arm Rehabilitation
This project is designed to use three-dimensional movement analysis and magnetic resonance (fMRI) neuroimaging techniques to examine the brain activity and motor behavior changes associated with constraint-induced (CI) therapy…
- Trial name
- BCAR (NCT04989920)
- Testing
- Experimental group: CIMT group (Constraint-Induced Movement Therapy)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Southern California
Stroke, Rehabilitation
Virtual Reality-Based Upper Limb Rehabilitation in Chronic Stroke
This randomized controlled study aims to evaluate the effectiveness of non-immersive virtual reality-based rehabilitation using the MindMotion™ GO system compared with conventional occupational therapy for improving upper limb…
- Conditions
- Stroke, Rehabilitation, Upper Limb Paresis, Chronic Stroke Patient
- Trial name
- NCT07534124
- Testing
- Non-Immersive Virtual Reality Rehabilitation, Occupational Therapy
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- Universidad Complutense de Madrid
Ischemic Stroke
A Study Of Vagus Nerve Stimulation (VNS) With Mobility Training For Gait Recovery After Chronic Ischemic Stroke
The purpose of this study is to evaluate the safety, feasibility, and efficacy of vagus nerve stimulation (VNS) paired with mobility training to improve lower extremity function and gait in individuals with chronic ischemic…
- Trial name
- NCT07291024
- Testing
- Vagus nerve stimulation (VNS) paired with mobility training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
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