Clinical trials: Brain Stroke
Stroke, Cardiovascular, Stroke, Acute
Stroke in Egyptian Clinical REgisTry
This is a multi-institutional registry database for the patients with stroke and cerebrovascular diseases. Stroke is the second leading cause of death in the Egypt.
- Conditions
- Stroke, Cardiovascular, Stroke, Acute, Stroke Hemorrhagic, Stroke Spinal Cord
- Trial name
- SECRET (NCT03723382)
- Testing
- SECRET structured 5 bundles of standard healthcare services
- Where
- Egypt
- Volunteers
- 50,000 people
- Sponsor
- Society of Minimally Invasive Neurological Therapeutic Procedures
Stroke
Enhanced Treadmill Gait Training With Lower Limb Support After Stroke
This series of single case studies aims to test the feasibility and acceptability of an enhanced treadmill system for the recovery of gait function in stroke survivors.
- Trial name
- ENTRES (NCT03348215)
- Testing
- Enhanced Treadmill Training
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- University of Strathclyde
Ischemic Stroke
Efficacy of Transcranial Direct Current Stimulation in Acute Ischemic Stroke
Non-invasive brain stimulation (tDCS) such as transcranial direct current stimulation (TDCS) has been reported to be effective in improving motor performance and safe in participants with cerebral infarction.
- Trial name
- DAS (NCT04938076)
- Testing
- Transcranial direct current stimulation
- Where
- South Korea
- Volunteers
- 172 people
- Sponsor
- Incheon St.Mary's Hospital
Stroke
Transcranial Direct Current Stimulation and Cognitive Behavioural Programme on Post-stroke Fatigue
This study aims to evaluate the effect of transcranial direct current stimulation and cognitive behavioural programme on fatigue and its related outcomes among people with stroke.
- Trial name
- NCT06810817
- Testing
- tDCS & cognitive behavioral programme with home-based physical training, physical training
- Where
- Hong Kong
- Volunteers
- 75 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke
The Changes of Masticatory / Swallowing Functions and Oropharyngeal Muscle Mass on Sonography After Comprehensive Swallowing Training and Tongue - Pressure Resistance Training in Stroke Patients With Dysphagia
The aims of this study are: 1. Comparing the ultrasound imaging performance of swallowing and chewing function, tongue pressure and oropharyngeal muscle thickness in stroke patients with different levels of swallowing function 2.
- Trial name
- NCT06269718
- Testing
- swallowing therapy, IOPI therapy
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Stroke
Muscle Tone Changes in Acute Stroke According to Brain Injury
The purpose of the study is to examine connections between muscle tones, strength and function after stroke.
- Trial name
- NCT01041560
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Jyväskylä Central Hospital
Cardiovascular Diseases, Coronary Disease
Honolulu Heart Program
To investigate coronary heart disease and stroke among American men of Japanese ancestry who were living on the island of Oahu in 1965. Morbidity and mortality surveillance of the original cohort is continuing.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Cerebrovascular Accident, Heart Diseases
- Trial name
- NCT00005123
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Attention Deficit Disorder With Hyperactivity, Asthma
Study of an Intervention to Improve Problem List Accuracy and Use
The aim of this study is to identify patients with problem list gaps and intervene to correct these gaps by creating clinical decision support interventions that alert providers to likely problem list gaps and offer clinicians…
- Conditions
- Attention Deficit Disorder With Hyperactivity, Asthma, COPD, Breast Cancer
- Trial name
- MAPLE (NCT01105923)
- Testing
- MAPLE
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Brigham and Women's Hospital
Stroke
Analysis of Brain Diffusion Tensor Image in Stroke Patients
This clinical study aims to confirm the characteristics of the functional ansiotropy value according to the individual characteristics of stroke patients by taking brain diffusion tensor images for stroke patients and using the…
- Trial name
- NCT06047223
- Testing
- Magnetic resonanace imaging
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Bundang CHA Hospital
Critical Illness, Brain Injury
Adverse Events During Physical Therapy in Neurocritical ICU Patients
The goal of this observational study is to identify the clinical, neurological, hemodynamic, and respiratory variables associated with the occurrence of adverse events during physical therapy interventions in adult neurocritical…
- Conditions
- Critical Illness, Brain Injury, Stroke, Subarachnoid Hemorrhage
- Trial name
- NCT07901140
- Testing
- Physical Therapy Intervention
- Where
- 2 sites in Mexico
- Volunteers
- 47 people
- Sponsor
- Hospital H+ Queretaro
Ischemic Stroke, Acute
Brain-Oscillation-Synchronized Stimulation to Enhance Motor Recovery in Early Subacute Stroke
We will investigate the therapeutic efficacy of EEG-synchronized noninvasive repetitive transcranial magnetic stimulation (rTMS) in the early subacute phase after ischemic stroke to improve upper limb motor rehabilitation.
- Trial name
- Boss-Stroke (NCT05600374)
- Testing
- Bossdevice
- Where
- 4 sites in Germany
- Volunteers
- 144 people
- Sponsor
- University Hospital Tuebingen
Spasticity as Sequela of Stroke
Observational Longitudinal Study on the Outbreak and Management of Stroke Related Spasticity
Stroke is one of the leading cause of death and disability worldwide. Post-stroke spasticity (PSS) is outbreak after a stroke and is featured by disabling muscle stiffness.
- Trial name
- COLOSSEO (NCT05379413)
- Testing
- Botulinum toxin type A
- Where
- 4 sites in Italy
- Volunteers
- 960 people
- Sponsor
- Campus Bio-Medico University
Symptomatic Chronic Middle Cerebral Artery Occlusion, Infarction, Middle Cerebral Artery
Extracranial-intracranial Bypass Surgery for Symptomatic Chronic Middle Cerebral Artery Occlusion: the CMOSS-2 Trial
The CMOSS-2 trial is a government-funded, prospective, multicenter, randomized controlled trial. It will recruit symptomatic chronic occlusion of the middle cerebral artery in patients with severe hemodynamic insufficiency.
- Trial name
- NCT05899582
- Testing
- Extracranial-Intracranial Bypass Surgery, Medical treatment alone
- Where
- China
- Volunteers
- 420 people
- Sponsor
- Xuanwu Hospital, Beijing
Intracerebral Hemorrhage
Safety of NXY-059 for the Treatment of Patients Who Have Suffered From a Stroke
This study will determine if NXY-059 is safe in patients with an acute stroke caused by bleeding in the central nervous system. The primary objective was to assess the safety and tolerability of NXY-059 compared to placebo.
- Trial name
- NCT00075959
- Testing
- NXY-059
- Where
- 64 sites in United States
- Volunteers
- 600 people
- Sponsor
- AstraZeneca
Ischemic Stroke, Hemorrhagic Stroke
A Randomized Trial Comparing 2 Methods for Rapid Induction of Cooling in Stroke Patients, Cold Infusions vs. RhinoChill (iCOOL 1)
Mild hypothermia improves outcome in patients with global cerebral ischemia after cardiac arrest. Hypothermia seems promising also in other acute hypoxic-ischemic or in brain swelling associated cerebrovascular disease.
- Trial name
- iCOOL 1 (NCT01573117)
- Testing
- RhinoChill, Cold crystalloid infusions, 0.9%NaCl or Ringer's solution
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Heidelberg
Cerebral Vascular Accident (CVA)
Predictive Value of Copeptin in the Diagnosis of Acute Ischemic Stroke
In the USA, every year 795,000 patients suffer a cerebral vascular accident (CVA), which represents a yearly cost of $73.7 billion.
- Trial name
- NCT01960478
- Testing
- (for each intervention), Blood test
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Strasbourg, France
Stroke, TIA
Diabetes in Minor Stroke/TIA, Glucose Tolerance and Haemostasis, a Long-term-follow-up Study and Intervention With Yoga
In acute stroke patients about 20 % have known diabetes. There is a doubled risk of recurrent stroke in diabetic patients. It has been shown that antiplatelet drugs are not as effective in diabetic patients as in non-diabetic…
- Trial name
- NCT01648985
- Testing
- Diabetes in stroke/TIA
- Where
- Sweden
- Volunteers
- 144 people
- Sponsor
- Karolinska Institutet
Healthy Volunteers
An Investigational Study to Assess the Effect of BMS-986177 on Aspirin in Healthy Participants
The purpose of this study is to investigate the effect of taking multiple doses of BMS-986177 when aspirin is taken once-daily. Eligible participants will receive twice-daily doses of BMS-986177 or placebo, with a once-daily dose…
- Trial name
- NCT03341390
- Testing
- Aspirin, BMS-986177
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Ischemic Stroke, Stroke Rehabilitaion
Neurological Rehabilitation and Neuroplasticity After Ischemic Stroke
This observational study evaluates the effects of neurological rehabilitation on biological markers associated with neuroplasticity and neurotransmitter profiles in patients after ischemic stroke.
- Trial name
- NCT07899710
- Volunteers
- 60 people
- Sponsor
- Medical University of Lodz
Stroke Ischemic, Stroke Acute
Posterior Circulation ASTRAL Prognostic Score
The goal of this study is to develop a prognostic score for ischemic posterior circulation strokes, based on our previous work on with the ASTRAL scores (Acute STroke Registry and Analysis of Lausanne) on overall stroke…
- Conditions
- Stroke Ischemic, Stroke Acute, Posterior Circulation Brain Infarction, Risk Score
- Trial name
- NCT05906420
- Testing
- ASTRAL prognostic score
- Where
- 2 sites in Greece, Switzerland
- Volunteers
- 2,000 people
- Sponsor
- University of Thessaly
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