Clinical trials: Brain-Computer Interface
Rehabilitation, Stroke
the Effectiveness of Brain-computer Interface-pedaling Training System on the Rehabilitation of Stroke
Stroke has become the first cause of death and disability among Chinese adults. 70%-80% of patients cannot live independently due to disability, which has brought a heavy burden to families, medical institutions and society.
- Conditions
- Rehabilitation, Stroke, Brain-computer Interface
- Trial name
- BCI-PT (NCT04612426)
- Testing
- Brain-computer Interface-Pedaling Training System, Traditional Pedaling Training System
- Where
- China
- Volunteers
- 30 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Glaucoma, Macular Degeneration
BCI and Evaluation of Visual and Task Performance in Subjects With Eye Diseases
The purpose of this research study is to better understand the impact of visual impairment caused by different eye diseases on the ability to perform daily activities and compare it to that in patients without eye diseases.
- Conditions
- Glaucoma, Macular Degeneration, Glaucoma Suspect, Optic Neuropathy
- Trial name
- NCT03318549
- Testing
- Visual Performance tests, Brain-computer interface
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Miami
Stroke
Assistive Soft Robotic Glove Intervention Using Brain-Computer Interface for Elderly Stroke Patients
This research aims to integrate and develop a novel Brain-Computer Interface (BCI) controlled soft robotic glove, evaluate the ability of the glove in achieving common hand grasping postures and to assess the efficacy of the…
- Trial name
- NCT03277508
- Testing
- BCI Robot Assisted Hand Therapy, CPM Robot Assisted Hand Therapy
- Where
- Singapore
- Volunteers
- 11 people
- Sponsor
- National University Hospital, Singapore
Hemiparesis
Post-stroke Motor Rehabilitation Using Functional Near-infrared Spectroscopy-based Brain-computer-interface
Chronic stroke survivors suffering from weaknesses or movement difficulties in their hand/arm are provided a system to aid in at-home rehabilitation for 6 weeks.
- Trial name
- fNIRS-PROMOTE (NCT05258591)
- Testing
- Axem Home
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Axem Neurotechnology Inc.
Depression, Major Depressive Disorder
Non-invasive BCI and Application Verification for Depressed People
Major Depressive Disorder (MDD) is a serious mental illness and public health problem that poses threat to both physical and mental health.
- Conditions
- Depression, Major Depressive Disorder, Bipolar Depression
- Trial name
- NCT06417437
- Testing
- SSRI, rTMS, Neuro-Feedback
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Depressive Sympotoms
Real-Time EEG Neurofeedback Using a Subject-Independent Classifier in Women With Depressive Symptoms
This completed feasibility study examined whether right-handed women aged 18-35 years with mild-to-moderate depressive symptoms could use real-time electroencephalography (EEG) neurofeedback based on a subject-independent…
- Trial name
- SIC-EEG-NF (NCT07815457)
- Testing
- Contingent Subject-Independent Classifier-Based EEG Neurofeedback
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Stroke Sequelae, Brain Ischemia
EEG Based BCI for Upper Limb Rehabilitation in Stroke
Biomedical and Engineering approaches form a key element to neurological rehabilitation of upper limbs. Brain Computer Interface (BCI) using Motor execution and Motor Imagery are known to aid motor recovery in stroke.
- Trial name
- NCT04188132
- Testing
- EEG -BCI based Feedback for rehabilitation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Houston
Stroke, Upper Extremity Paresis
BCI-FES for Upper Limb Rehabilitation in Chronic Stroke
The objective of this research is to evaluate the efficacy of an experimental therapy for motor recovery of the arm after a stroke, which includes the application of a functional electrical stimulation therapy coupled to P-300…
- Conditions
- Stroke, Upper Extremity Paresis, Neuronal Plasticity
- Trial name
- BCI-FES (NCT06409754)
- Testing
- Functional Electrical Stimulation Therapy coupled to a P-300 based Brain-Computer Interface, Conventional Physical Therapy
- Where
- Mexico
- Volunteers
- 26 people
- Sponsor
- Instituto Nacional de Rehabilitacion
Stroke, Hemiplegia
Brain-controlled Spinal Cord Stimulation in Participants With Chronic Stroke for Lower and Upper Limb Rehabilitation
The purpose of this clinical study is to evaluate the preliminary safety and effectiveness of using a cortical recording device (ECoG) combined with cervical and lumbar targeted epidural electrical stimulation (EES) of the spinal…
- Trial name
- Stroke-BSI (NCT07610850)
- Testing
- ARC-BSI Stroke system
- Where
- Switzerland
- Volunteers
- 3 people
- Sponsor
- Ecole Polytechnique Fédérale de Lausanne
Children With Motor Impairments
Utilizing an EEG-Based BCI Game to Evaluate Cognitive Skills in Children With Motor Impairments
This project aims to validate an EEG-based brain-computer interface (BCI) game as a cognitive assessment tool for children with motor impairments.
- Trial name
- NCT07109830
- Testing
- Cognitive assessment, NEPSY-II
- Where
- 2 sites in Canada
- Volunteers
- 73 people
- Sponsor
- University of Alberta
Stroke
Combined Transcranial Direct Current Stimulation and Motor Imagery-based Robotic Arm Training for Stroke Rehabilitation
Stroke is the most common cause of adult disability. Current treatments for functional loss of the upper extremity post-stroke remain limited in efficacy, particularly for those with moderate to severe impairment.
- Trial name
- NCT01897025
- Testing
- real-tDCS with MI-BCI
- Where
- Singapore
- Volunteers
- 42 people
- Sponsor
- National University Hospital, Singapore
Amyotrophic Lateral Sclerosis, Neurodegenerative Disease
EEG-Based Brain-Computer Interface Project for Individuals With Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic lateral sclerosis (ALS) is a progressive neuromuscular condition characterized by weakness, muscle wasting, fasciculations and increased reflexes.
- Conditions
- Amyotrophic Lateral Sclerosis, Neurodegenerative Disease, Motor Neuron Disease
- Trial name
- BCI (NCT00718458)
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Drexel University College of Medicine
Spinal Cord Injury, ALS (Amyotrophic Lateral Sclerosis)
Clinical Outcome Assessment for AT & BCI
Many individuals with severe motor impairments rely on Assistive Technologies (ATs) or Brain-Computer Interfaces (BCIs) to interact with digital devices such as their computers.
- Trial name
- NCT07407725
- Testing
- Eye Tracker, Mouth Operated Joystick, Non-invasive electroencephalogram (EEG) Headset
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
ALS, Amyotrophic Lateral Sclerosis
Cortex Changes in Real/Imagined Movements in Amyotrophic Lateral Sclerosis (ALS)
The purpose of this study is to track areas of the brain, via functional magnetic resonance imaging (fMRI), that retain structural and functional integrity throughout the lifespan of people with amyotrophic lateral sclerosis…
- Trial name
- NCT00809224
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Peripheral Facial Palsy, Pulsed Radiofrequency
Non-Invasive Brain-Computer Interface Combined With Transcranial Electrical Stimulation for Peripheral Facial PalsyStimulation in the Treatment of Peripheral Facial Palsy
To evaluate the efficacy and safety of treating peripheral facial palsy using a non-invasive brain-computer interface combined with transcranial direct current stimulation (tDCS).
- Conditions
- Peripheral Facial Palsy, Pulsed Radiofrequency, Brain-Computer Interface, Transcranial Direct Current Stimulation
- Trial name
- NCT07327710
- Testing
- Brain-Computer Interface （BCI）, Pulsed Radiofrequency （PRF）, Standard Therapy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nanjing Medical University
Traumatic Brain Injury
Testing Devices That Involve the Sense of Touch in Subjects With Traumatic Brain Injury
Background: Previous studies have shown that computer-based devices that simulate everyday tasks can be helpful for evaluation and rehabilitation in people who have had strokes.
- Trial name
- NCT01404494
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Stroke
Treatment of Chronic Stroke With IpsiHand
The ultimate goal of this project is to develop a functioning and clinically feasible method for restoring function to motor-impaired stroke survivors. This ultimate goal will be approached through two different means.
- Trial name
- NCT02552368
- Testing
- IpsiHand Device
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Stroke
Lifescapes System in Post-stroke Hand Recovery
Stroke is a leading cause of long-term disability, with 30-60% of survivors remaining unable to use their affected arms after discharge.
- Trial name
- NCT07784920
- Testing
- Lifescapes
- Where
- 2 sites in Singapore
- Volunteers
- 32 people
- Sponsor
- National University Hospital, Singapore
Stroke
Stroke Rehabilitation Program Based on a Powered Lower Extremity Exoskeleton in Chile
This research will study the effects of a rehabilitation program assisted by a powered lower extremity exoskeleton in patients after stroke.
- Trial name
- NCT04228224
- Testing
- Robot-assisted training with a lower extremity powered exoskeleton (H3 Exoskeleton, Spain), Conventional gait rehabilitation
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Corporación de Rehabilitación Club de Leones Cruz del Sur
Autism Spectrum Disorder (ASD)
BCI Training for Social Cognition and Error Monitoring in ASD
Social cognition seems to develop atypically in autism, particularly in processes such as faces perception, joint attention and social information processing.
- Trial name
- LEARNAUT (NCT06829303)
- Testing
- Emotional Facial Expression Paradigm (EFP), Speller task
- Where
- Portugal
- Volunteers
- 28 people
- Sponsor
- University of Coimbra