Clinical trials: Brain-Computer Interface
Stroke Sequelae, Motor Disorders
Clinical Validation of a Hybrid BCI-controlled FES for Upper Limb Rehabilitation After Stroke
The RECOMMENCER project aims at developing and testing a novel hybrid Brain Computer Interface device based on cortico-muscular connectivity, that will be employed to activate Functional Electrical Stimulation (FES) of upper limb…
- Trial name
- RECOMMENCER (NCT05511207)
- Testing
- RECOM - hBCI training, CTRL - upper limb training with FES
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Donatella Mattia
Pain, Chronic
Brain-Computer Interface (BCI)-Based Feedback for Chronic Pain Management
The feasibility study proposed here will primarily examine the sensitivity of an electroencephalogram (EEG)-based Brain Computer Interface (BCI) in detecting significant differences in brain signals in patients with chronic low…
- Trial name
- NCT03032497
- Testing
- EEG-based BCI analysis of fear avoidance
- Where
- Singapore
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Attitude to Computers
Evaluation of Evoked Potentials Recording Modalities in Healthy Volunteer Population
The purpose of this study is to compare three different techniques of EEG recording for extraction of P300 Evoked Related Potentials (ERPs).
- Trial name
- 3Electrods (NCT01518426)
- Testing
- EEG Recording (Emotiv)
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Ischemic Stroke, Intracranial Haemorrhage
Prospective, Randomized, Parallel-Controlled Study of Brain Computer Interface Integrated Robotic Mirror Therapy for Post-Stroke Upper Limb Motor Function Disorder
This study aims to utilize non-invasive brain-computer interface technology in conjunction with mirror therapy to design a new paradigm for rehabilitation robots to induce compensatory movements on the healthy side in stroke…
- Conditions
- Ischemic Stroke, Intracranial Haemorrhage, Brain-Computer Interfaces, Rehabilitation Exercise
- Trial name
- BCI-RMT (NCT07553416)
- Testing
- Brain computer interface-robotic mirror therapy
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Beijing Tiantan Hospital
Hemiparetic Cerebral Palsy
Using Neurotechology to Help Children With Physical Disability Due to Cerebral Palsy
Hemiparetic cerebral palsy is a condition in which one side of a child's body becomes weak due to brain injury occurring around birth, often caused by stroke.
- Trial name
- NCT07269353
- Testing
- Brain Computer Interface - Functional Electrical Stimulations
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University of Alberta
ALS (Amyotrophic Lateral Sclerosis), TBI Traumatic Brain Injury
Augmented Reality BCI Longitudinal Study for Persons With ALS, Stroke, TBI and SCI Utilizing Cognixion + Apple Vision Pro
The goal of this study is refine the usability of a BCI capable communication platform. The study will take place in the United States area and will enroll up to 10 participants with late stage ALS, traumatic brain injury (TBI)…
- Conditions
- ALS (Amyotrophic Lateral Sclerosis), TBI Traumatic Brain Injury, SCI - Spinal Cord Injury, Stroke
- Trial name
- NCT07209943
- Testing
- Cognixion + Apple Vision Pro
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cognixion
Tetraplegia, Locked-in Syndrome
Investigation on the Cortical Communication (CortiCom) System
The CortiCom system consists of 510(k)-cleared components: platinum PMT subdural cortical electrode grids, a Blackrock Microsystems patient pedestal, and an external NeuroPort Neural Signal Processor.
- Conditions
- Tetraplegia, Locked-in Syndrome, Brainstem Stroke, Amyotrophic Lateral Sclerosis
- Trial name
- CortiCom (NCT03567213)
- Testing
- Surgical implantation of CortiCom system
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Johns Hopkins University
Quadraplegia
Robust Intelligent Keyboard for Quadraplegic Patients
This is multi-center prospective randomized trial evaluating the effectiveness of a new brain-computer interface for communication of quadriplegic patients in a clinical context.
- Trial name
- PVCRoBIK (NCT01707498)
- Testing
- Scanning device, RoBIK Brain-Computer Interface
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Stroke
Smart Technologies in Early Post-Stroke Rehabilitation
The goal of this interventional study is to evaluate the impact of applying different smart technologies during early rehabilitation after stroke.
- Trial name
- SMART-Stroke (NCT07171073)
- Testing
- RecoveriX, Gloreha Aria, E-Link System
- Where
- 2 sites in Lithuania
- Volunteers
- 200 people
- Sponsor
- Erika Endzelyte
Spinal Cord Injury
BCI and FES for Hand Therapy in Spinal Cord Injury
This study will assess whether functional recovery of the hand muscles in patients with spinal cord injury is enhanced when electrical stimulation of the muscles is delivered actively by means of using the electroencephalography…
- Trial name
- NCT01852279
- Testing
- BCI-FES, Passive muscle stimulation
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- NHS Greater Glasgow and Clyde
Stroke
BCI-Based Control for Ankle Exoskeleton T-FLEX: Comparison of Visual and Haptic Feedback With Stroke Survivors
This protocol will developed an assessment of the T-FLEX device controlled by Brain-Computer Interface in patients with Stroke.
- Trial name
- NCT04995367
- Testing
- Implementation of a BCI system integrated to the T-FLEX lower-limb exoskeleton in post-stroke patients.
- Where
- Chile
- Volunteers
- 5 people
- Sponsor
- Corporación de Rehabilitación Club de Leones Cruz del Sur
Spinal Cord Injuries
Brainwave Control of a Wearable Robotic Arm for Rehabilitation and Neurophysiological Study in Cervical Spine Injury
CSI:Brainwave is a multidisciplinary neurophysiological project, developed by the Lab of Medical Physics, School of Medicine, Aristotle University of Thessaloniki and supported by two Neurosurgical Departments.
- Trial name
- CSI:Brainwave (NCT02443558)
- Testing
- Brain-Computer Interface control of robotic arms., MERCURY v2.0 robotic arms
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Internet Gaming Disorder
Mechanism of BCI-Based Dual-Target Neurofeedback Training in Improving Cognitive Control Deficits in Internet Gaming Disorder
Addressing the three core issues in research on cognitive control deficits in Internet Gaming Disorder (IGD)-unclear neural mechanisms, limited intervention targets, and poor patient compliance-this project innovatively…
- Trial name
- NCT07843615
- Testing
- "Activate Neural Circuits + Promote Social Rewards" Dual-target Neurofeedback Training, "Activate Only the Neural Circuits" Neurofeedback Training
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Affiliated Hospital of Bengbu Medical University
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorders
Brain-Computer Interface-based Programme for the Treatment of ASD/ADHD
This project involves creating a novel and personalised BCI training system that targets social and communication difficulties, and inattentive symptoms problems often found in ASD/ADHD children.
- Trial name
- ASDBCI (NCT02618135)
- Testing
- Intervention Group, Control Group
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Duke-NUS Graduate Medical School
Functional Neurological Disorder, Conversion Disorder
Brain-computer Interface Rehabilitation And Virtual Environments in Functional Neurological Disorder (BRAVE-FND)
The purpose of this study is to determine whether a course of rehabilitation using a device called a brain-computer interface can change the level of control people feel over bodily movements, in functional neurological disorder.
- Conditions
- Functional Neurological Disorder, Conversion Disorder, Functional Neurological Disorders, Conversion Disorder With Weakness/Paralysis
- Trial name
- BRAVE-FND (NCT07006415)
- Testing
- Brain-computer interface rehabilitation
- Volunteers
- 24 people
- Sponsor
- King's College London
Mild Cognitive Impairment (MCI), Early Stages of Cognitive Decline
Mild Cognitive Impairment Community Screening and Early Intervention Via Stem Cell Therapy and Wearable Brain Computer Interface Device.
This study aims to evaluate the efficacy of community-based early detection and targeted interventions, including stem cell therapy and wearable non-invasive brain-computer interface (BCI) devices, for Mild Cognitive Impairment…
- Conditions
- Mild Cognitive Impairment (MCI), Early Stages of Cognitive Decline, Alzheimer's Disease Dementia, Alzheimer's Disease Diagnosis
- Trial name
- MCITestCare (NCT07214974)
- Testing
- Structured wellness care, Wearable brain-computer interface devices, Stem Cell Therapy - Experimental
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Noah Tech, Corp.
Spinal Cord Injury, Tetraplegia C1-C4
Innovative Brain-Computer Interface for People With Spinal Cord Injury
The goal of this clinical trial is to demonstrate control of digital devices through a brain implant in people with spinal cord injury.
- Conditions
- Spinal Cord Injury, Tetraplegia C1-C4, Quadriplegia
- Trial name
- INTENSE-BCI (NCT07640711)
- Testing
- ECoG (electrocorticography) sensing
- Where
- Netherlands
- Volunteers
- 1 people
- Sponsor
- UMC Utrecht
Acquired Brain Injury Including Stroke, Epilepsy
Cognitive Rehabilitation Using Neurofeedback With Brain-computer Interface
The goal of this clinical trial is to determine whether a Brain-Computer Interface Neurofeedback Training (BCI-NFT) programme can improve cognitive outcomes, and whether electroencephalography (EEG)-based measures can serve as…
- Trial name
- NCT07828496
- Testing
- Brain-computer interface with neurofeedback with 3D game sessions
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Stroke, Motor Dysfunction
Closed-Loop SCS-BCI for Post-Stroke Hemiplegia
This study evaluates a new closed-loop rehabilitation system for stroke survivors with arm weakness. The system combines a brain-computer interface (BCI, a special cap that reads brain signals), spinal cord stimulation (a…
- Conditions
- Stroke, Motor Dysfunction, Brain-computer Interface, Spinal Cord Stimulation (SCS)
- Trial name
- CL-SCS-BCI (NCT07903116)
- Testing
- Spinal Cord Stimulation, Non-invasive Brain-Computer Interface, Hand Exoskeleton
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Tiantan Hospital
Healthy
Brain Computer Interface Control of a Robotic Device
Noninvasive Brain-Computer Interfaces (BCIs) have been used to control a number of virtual and physical objects through the voluntary modulation of brain rhythms.
- Trial name
- NCT02069938
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Minnesota