Clinical trials: Brain-Computer Interface
Spinal Cord Injuries, Motor Disorders
DiSCIoser: Improving Arm Sensorimotor Functions After Spinal Cord Injury Via Brain-Computer Interface Training
The goal of this clinical trial is to validate the efficacy of a Brain-Computer Interface (BCI)-based intervention for hand motor recovery in subacute cervical spinal cord injured (SCI) patients during rehabilitation.
- Trial name
- DiSCIoser (NCT05637775)
- Testing
- EEG-based BCI system for (hands) Motor Imagery training, Control - MI intervention
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Attention Deficit Hyperactivity Disorder
Effectiveness of a Electroencephalogram (EEG) Biofeedback for the Treatment of ADHD
The aim of this study is to investigate if electroencephalogram (EEG) biofeedback incorporating the use of video games is effective in improving inattentive symptoms in children with ADHD.
- Trial name
- EEG (NCT00802490)
- Testing
- Brain-Computer Interface System
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- National Healthcare Group, Singapore
Quadraplegia
Robust Intelligent Keyboard for Quadraplegic Patients
This is multi-center prospective randomized trial evaluating the effectiveness of a new brain-computer interface for communication of quadriplegic patients in a clinical context.
- Trial name
- PVCRoBIK (NCT01707498)
- Testing
- Scanning device, RoBIK Brain-Computer Interface
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Stroke, Rehabilitation
Using Upper Limb Rehabilitation Robot in Stroke Patient Rehabilitation
A robot arm for upper limb rehabilitation is intended to achieve rehabilitation effects through the study of robot control theory and the integration of sensors such as sEMG.
- Trial name
- NCT06113380
- Testing
- NTUH-ii, am upper limb rehabilitation robot arm, Traditional upper limb physical therapy
- Where
- Taiwan
- Volunteers
- 68 people
- Sponsor
- National Taiwan University Hospital
Cerebral Palsy, Pediatric Stroke
BCI@Home: Brain Computer Interface Solutions to Enable Youth Living With Severe Disabilities
The goal of this trial is to evaluate use of brain computer interfaces (BCI) at home for children with severe severe physical disabilities. The main questions it aims to answer are: 1.
- Conditions
- Cerebral Palsy, Pediatric Stroke, Genetic Condition, Acquired Brain Injury (Including Stroke)
- Trial name
- BCI@home (NCT07073378)
- Testing
- Brain computer interface
- Where
- 2 sites in Canada
- Volunteers
- 18 people
- Sponsor
- University of Calgary
Deep Brain Stimulation, Parkinson's Disease (PD)
Testing of an Interface for Synchronizing tACS-DBS With a Phase-locked-loop
The investigators aim to test an interface to phase-lock transcranial alternating current stimulation (tACS) and deep brain stimulation (DBS) for future studies investigating the effects of different time-lags between DBS and…
- Trial name
- NCT07139093
- Testing
- DBS-coupled tACS
- Where
- Germany
- Volunteers
- 2 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Stroke
Longitudinal Multimodal Profiling of Balance and Gait In Stroke
Balance and gait recovery is a critical aspect of post-stroke motor rehabilitation. Researchers have effectively utilized EEG to investigate different aspects of lower limb motor control, however there are several technical…
- Trial name
- NCT06187467
- Testing
- Clinical and technological-aided assessments and questionnaires
- Where
- Singapore
- Volunteers
- 16 people
- Sponsor
- Tan Tock Seng Hospital
Acute Ischemic Stroke, Stroke Rehabilitation
Safety and Efficacy of Early Non-invasive Brain-Computer Interface-Based Rehabilitation in Acute Ischemic Stroke
This is a single-center, prospective, randomized, sham-controlled pilot clinical study designed to evaluate the efficacy, safety, and feasibility of early non-invasive electroencephalography-based brain-computer interface…
- Trial name
- SeeBCI (NCT07585058)
- Testing
- Real EEG-BCI Training, Standard Early Rehabilitation
- Volunteers
- 60 people
- Sponsor
- Shandong Provincial Hospital
Healthy Participants
Dopamine and Brain Computer Interface
The use of Brain-Computer Interface system (BCI system) allows for the detection of neurophysiological signals on the surface of the head and provides feedback to subjects or patients.
- Trial name
- BCI_LDOPA (NCT06729658)
- Testing
- Madopar
- Where
- Germany
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Max Planck Institute for Human Cognitive and Brain Sciences
Anterior Cruciate Ligament Reconstruction, Total Hip Arthroplasty (THA)
Brain-Computer Interface Visualization Training to Optimize Muscle Activation Following Orthopaedic Surgery
After orthopedic surgeries like knee or hip replacement, some patients struggle to fully activate their muscles due to a condition called Arthrogenic Muscle Inhibition (AMI).
- Conditions
- Anterior Cruciate Ligament Reconstruction, Total Hip Arthroplasty (THA), Total Knee Arthroplasty, Hip Arthroscopy
- Trial name
- iBrainTechRCT (NCT07020312)
- Testing
- Visualization training with neurofeedback, Standard post-surgical rehabilitation therapy
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Rush University Medical Center
Stroke, Complication, Stroke
Neuromotor Prosthetic to Treat Stroke-Related Paresis
The purpose of the research is to develop a new medical device prototype to restore functional movement of an arm made weak due to a chronic stroke
- Conditions
- Stroke, Complication, Stroke, Stroke Sequelae, Hemiparesis
- Trial name
- Cortimo (NCT03913286)
- Testing
- Cortimo
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Thomas Jefferson University
Stroke
Hybrid Brain Computer Interface for Control of Sensory - Motor Coupling in Post - Stroke Rehabilitation
HYBIS project aims to develop an innovative and unique hybrid Brain-Computer Interface (BCI) system. This BCI system is envisioned as a novel tool for targeted reinforcement of sensory motor coupling, specifically dedicated for…
- Trial name
- HYBIS (NCT05152108)
- Testing
- BCI feasibility test
- Where
- Serbia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Incomplete Spinal Cord Injury
The Use of Electromagnetic Field (EMF) Treatment in Chronic Spinal Cord Injury (SCI) Patients
The purpose of this study is to further establish safety and efficacy of the BQ EMF treatment of chronic SCI subjects who demonstrate stability in The Graded and Redefined Assessment of Strength, Sensibility and Prehension…
- Trial name
- NCT04050696
- Testing
- BQ 1.2
- Where
- 3 sites in United States, Israel
- Volunteers
- 8 people
- Sponsor
- BrainQ Technologies Ltd.
Spinal Cord Injury
A Clinical Study of a Fully Implanted, Wireless and Functional BCI for Upper-Limb Functional Replacement in Tetraplegia Due to Spinal Cord Injury: Efficacy and Safety
This prospective, multicenter, single-arm clinical trial will enroll subjects with tetraplegia secondary to spinal cord injury. An implantable brain-computer interface system for compensatory hand motor function will be used to…
- Trial name
- "Triple-F" BCI (NCT07720882)
- Testing
- "Triple-F" BCI
- Where
- China
- Volunteers
- 32 people
- Sponsor
- NeuroXess Technology (shanghai) Co.,Ltd.
Alzheimer's Disease, Mild Cognitive Impairment
Brain-Computer Interface System for Training Memory and Attention in Elderly
The primary objective is to examine the efficacy of 8-weeks of a locally developed brain-computer interface based system intervention for improving attention and memory in healthy elderly and those with age related cognitive…
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Age-Related Cognitive Decline, Dementia
- Trial name
- NCT02228187
- Testing
- Brain-Computer Interface
- Where
- Singapore
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Duke-NUS Graduate Medical School
Chronic Stroke
Magnetic Brain Stimulation and Computer-based Motor Training for Rehabilitation After Stroke
The goal of the present clinical trial is to explore whether an innovative technology-based approach can help individuals who have had a stroke and can no longer move their hands with ease.
- Trial name
- NCT06116942
- Testing
- Active rTMS
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Max Planck Institute for Human Cognitive and Brain Sciences
Stroke
Tele BCI-FES for Upper -Limb Stoke Rehabilitation
The study aims to identify whether stroke survivors can intentionally modulate their brain signals for controlling an FES device to produce arm movements for home based rehabilitation.
- Trial name
- NCT05215522
- Testing
- The BCI-FES Intervention
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- University of Sheffield
Stroke
Effect of Brain-Computer Interfaced-Assisted Motor Imagery for Gait Retraining in Stroke Patients
Currently the process for stroke recovery is slow with majority of its treatments focused around physical therapy. Among the many methods employed to facilitate recovery in stroke, the use of motor imagery (MI) training may be…
- Trial name
- NCT02507895
- Testing
- MI-BCI
- Where
- Singapore
- Volunteers
- 26 people
- Sponsor
- National University Hospital, Singapore
Stroke
Brain Computer Interface (BCI) Based Robotic Rehabilitation for Stroke
The trial aims to test a novel rehabilitation device for subacute stroke hemiplegic upper limbs based on state-of-the-art non invasive Brain-Computer Interface (BCI) robotic rehabilitation in a clinical setting.
- Trial name
- NCT00955838
- Testing
- Rehabilitation technique
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- National Neuroscience Institute
Healthy
Brain Computer Interface Control of a Robotic Device
Noninvasive Brain-Computer Interfaces (BCIs) have been used to control a number of virtual and physical objects through the voluntary modulation of brain rhythms.
- Trial name
- NCT02069938
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Minnesota