Clinical trials: Brain-damaged Patients
Intestinal Microbiota Between Different Groups
Study of the Intestinal Microbiota
The intestinal microbiota is the set of numerous microorganisms (between 1012 and 1014 bacteria, viruses, parasites, and non-pathogenic fungi) that live in our digestive tract, mainly in the small intestine and colon.
- Trial name
- NEUROBIOTE (NCT07058961)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Rouen
Brain Damage, Health Behavior
A Neuropsychological Test Battery for the Assessment of Time Deficits
Time processing involves different abilities - i.e. estimating the duration of an event and moving in past and future time - and it is a fundamental ability in everyday life.
- Trial name
- NCT04419818
- Testing
- Virtual Reality
- Where
- Italy
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Cerebrovascular Disorders, Brain Lesions
Neuropsychological and Brain Medical Imaging Study in Patients With Brain Damage
Two groups of subjects will be constitute: (i) patients with circumscribed brain injury (including stroke, vascular malformations, tumor or circumscribed infectious lesions) or degenerative disorders and selective cognitive…
- Conditions
- Cerebrovascular Disorders, Brain Lesions, Degenerative Diseases, Developmental Pathology
- Trial name
- CORAC (NCT01849549)
- Testing
- Neuropsychological testing, MRI
- Where
- France
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Brain Damage
Rehabilitation Treatment of Time Deficits in Brain-damaged Patients
The efficacy of an innovative rehabilitation treatment for deficit in time processing is tested in right brain damaged patients.
- Trial name
- NCT04373837
- Testing
- Prismatic googles inducing prismatic adaptation (PA) associated to Virtual Reality (VR), Neutral googles inducing no-adaptation (NA) associated to Virtual Reality (VR)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Brain Disease
Temporal Disorders in Left and Right Brain-Damaged Patients
Time is an important function that permeates our everyday activities but it has been so far significantly under-investigated in neurological patients.
- Trial name
- NCT04424199
- Testing
- Rightward Attentional Shift (R-PA), Leftward Attentional Shift (L-PA)
- Where
- Italy
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Brain Damage
Cognitive Abilities in Brain Damaged Patients
The presence of damage to the central and / or peripheral nervous system resulting from pathologies of a different nature (such as multiple sclerosis, Parkinson's disease, dementia, cranial trauma, stroke, epilepsy or other…
- Trial name
- Cog (NCT03344731)
- Testing
- Cognitive evaluation, Non-invasive brain stimulation
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Stroke, Infarction; Posterior Cerebral Artery
Restoration of Vision After Stroke
Occipital stroke is associated with homonymous visual field defects (occurring on one side of the visual field). Despite spontaneous recovery, some degree of defect is often permanent.
- Conditions
- Stroke, Infarction; Posterior Cerebral Artery, Hemianopsia
- Trial name
- REVIS (NCT02405143)
- Testing
- Active tACS using DC-Stimulator MC
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- Helsinki University Central Hospital
Stroke
Assessment of Robotic Assistance on Gait Parameters Among Healthy Subjects and Brain Damaged Patients
The main objective of this study is to quantitatively assess the robotic assistance given by an exoskeleton on patients gait parameters. Patients will be asked to walk with- and without the exoskeleton on a treadmill.
- Trial name
- MARAT (NCT05264103)
- Testing
- Exoskeleton for gait rehabilitation (Atalante)
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Cerebral Palsy, Perceptual Disorders
Motor and Cognitive Functions in Acquired and Developmental Brain Damaged Patients
Neurological pathologies cause important and permanent disabilities in every day life. These pathologies can follow stoke, affecting two people per one thousand each year or cerebral palsy, affecting two births per one thousand…
- Conditions
- Cerebral Palsy, Perceptual Disorders, Hemiparesis
- Trial name
- NCT02543424
- Testing
- Motor, cognitive and neuropsychological assessment
- Where
- 2 sites in Belgium
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Brain Damage
Transcranial Doppler and Quantitative Pupillometry as Neurological Prognostic Factors in Brain Damaged Patients Admitted to Intensive Care Unit
Transcranial Doppler is performed daily in Intensive Care Unit in brain damaged patients. For a few years now, the measurement of the photomotor reflex by quantitative Pupillometry has been routinely performed in Intensive Care…
- Trial name
- NCT04846738
- Testing
- Transcranial Doppler, Pupillometry.
- Where
- France
- Volunteers
- 73 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Movement, Involuntary
Assessment of the Effects of Mental Practice on Tongue Strength in Brain-damaged Patients
The main objective is to evaluate the effects of action-observation training on tongue strength in brain-damaged patients.
- Trial name
- NCT04615598
- Testing
- Action observation
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Autonoma de Madrid
Brain-damaged Patients
Performance Evaluation of Pupillary Reactivity in Monitoring of Brain-damaged Patients in Intensive Care
The pupillary examination is a major component of the clinical examination and monitoring of brain-damaged patients in intensive care.
- Trial name
- NCT01796886
- Testing
- pupillometry data
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Stroke, Anosognosia
Improving Awareness for Spatial Neglect With tDCS
Brain-damaged patients can show severe neurological and cognitive deficits, and yet often remain strikingly unaware of these symptoms: this condition is called anosognosia.
- Conditions
- Stroke, Anosognosia, Neglect, Hemispatial
- Trial name
- ANOSO (NCT04845529)
- Testing
- transcranial direct current stimulation (tDCS)
- Volunteers
- 12 people
- Sponsor
- University of Geneva, Switzerland
Brain Injury
Macro- and Microcirculation Crosstalk in Brain-damaged Patients Under Anesthesia or in Intensive Care
In patients with severe brain injury, maintenance and control of blood pressure is at the very first point in the management strategy, whether in anesthesia or in intensive care.
- Trial name
- MICRONOR (NCT05285514)
- Testing
- Comparison of macro- and microcirculatory parameters
- Where
- France
- Volunteers
- 85 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Consciousness Disorder
Detection of Arousal With Facial Micro-expression in Severe Brain-damaged Patient
Severe brain injuries lead to disorders of consciousness after coma. During this awakening period, detection of arousal is critical to the adaptation of medical strategy, but global paralysis, including facial expression, make…
- Trial name
- DAME (NCT03023657)
- Testing
- Detection of arousal
- Where
- 2 sites in France
- Volunteers
- 3 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Traumatic Brain Injury With Prolonged Loss of Consciousness, Stroke
Evaluation of Consciousness by Brain-computer Interface in Severely Brain Damaged Patients
The objective of this study is to show that the measurement of auditory and vibro-tactile evoked potentials, or the recording of the EEG signal during a motor imaging task, can be used in routine clinical situations to explore…
- Conditions
- Traumatic Brain Injury With Prolonged Loss of Consciousness, Stroke, Brain Hypoxia
- Trial name
- AWAKE (NCT03998930)
- Testing
- Clinical evaluation of consciousness by the Coma Recovery Scale Revised (CRS-R)
- Where
- 4 sites in France
- Volunteers
- 9 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Brain-damaged Patients
IRM Cognition in Patients With Head Trauma
Longitudinal descriptive study of a cohort of twenty brain-damaged patients for a two years period.
- Trial name
- NCT03181373
- Testing
- Cognitive rehabilitation program
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Clermont-Ferrand