Clinical trials: Breakthrough Bleeding, open to volunteers
Abnormal Uterine Bleeding, Endometriosis
Performance of SYMMCORA® vs. V-Loc® Suture Material in Patients Undergoing Laparoscopic Total Hysterectomy
The aim of this study is to show the superiority of the new unidirectional barbed suture (SYMMCORA® mid-term, unidirectional) to conventional suture material in terms of time to perform the vaginal cuff closure during gynecologic…
- Conditions
- Abnormal Uterine Bleeding, Endometriosis, Uterine Prolapse, Uterine Cancer
- Trial name
- BARHYSTER (NCT06024109)
- Testing
- Closure of the Vaginal Cuff after Total Hysterectomy
- Where
- 2 sites in Germany, Spain
- Volunteers
- 132 people
- Sponsor
- Aesculap AG
Abnormal Uterine Bleeding, Analgesia
Combined Ketorolac and Lidocaine Paracervical Block for Office Hysteroscopy
A randomized double-blind placebo controlled trial comparing the effect of a combined ketorolac and lidocaine paracervical block with a standard lidocaine paracervical block on procedure related pain with office hysteroscopies.
- Conditions
- Abnormal Uterine Bleeding, Analgesia, Paracervical Block
- Trial name
- NCT06653400
- Testing
- paracervical block, Lidocaine, ketorolac
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Menorrhagia, Abnormal Uterine Bleeding
Efficacy of Calcium Dobesilate Versus Tranexamic Acid for Treating Heavy Menstrual Bleeding
The goal of this clinical trial is to determine if calcium dobesilate is an effective alternative to tranexamic acid for treating menorrhagia in women aged 18 to 39 years.
- Trial name
- NCT06763094
- Testing
- Calcium dobesilate (Doxium), Tranexamic Acid
- Volunteers
- 100 people
- Sponsor
- University of Health Sciences Lahore
Uterine Fibroids (UF), Abnormal Uterine Bleeding Unrelated to Menstrual Cycle
POPQ Associated With Total Laparoscopic Hysterectomy
The goal of this observational study is to evaluate the impact of different hysterectomy (removal of the uterus) techniques on the risk of pelvic organ prolapse (situation when one or more of your pelvic organs like your bladder…
- Conditions
- Uterine Fibroids (UF), Abnormal Uterine Bleeding Unrelated to Menstrual Cycle, Endometrial Hyperplasia, Pelvic Organ Prolapse (POP)
- Trial name
- POP-LAP (NCT07137299)
- Testing
- Questionnaire and Physical Exam
- Where
- 4 sites in Poland
- Volunteers
- 2,000 people
- Sponsor
- Medical University of Silesia
Adenomyosis of Uterus
Association of Ultrasound Features of the Myometrium Suggestive of Adenomyosis and Clinical Symptoms
The goal of this study/research is to assess the relationship between ultrasound features of the myometrium suggestive of adenomyosis and clinical symptoms of adenomyosis and to establish a reporting system for adenomyosis…
- Trial name
- MUSA3 (NCT07397715)
- Where
- 5 sites in Belgium, Poland and 2 more
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Swiss GO Trial Group
Cesarean Section Complications, Uterine Bleeding
Platelet Rich Plasma for Uterine Scar
When vessel wall injury occurs, platelets become activated, releasing more than 30 bioactive proteins, many of which have a fundamental role in hemostasis, inflammation and ultimate wound healing.
- Conditions
- Cesarean Section Complications, Uterine Bleeding, Pelvic Pain, Menstrual Irregularity
- Trial name
- AA-PRP (NCT05224726)
- Testing
- Platelet Rich Plasma
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Endometrial Cancer
Detection of Endometrial Cancer Through Risk Modelling
The study goal is to investigate a non-invasive approach to predict endometrial cancer (EC) risk, better understand disease progression and identify opportunities for intervention.
- Trial name
- DETECTR (NCT06268626)
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Hysteroscopy, Assessment Methods in Medical Training
Assessment of Hysteroscopy Skills With a New Assessment Tool
Objective To investigate validity of the hysteroscopy assessment tool (HYSAT) for assessment of competence in a clinical environment.
- Conditions
- Hysteroscopy, Assessment Methods in Medical Training, Medical Education, Diagnostic Hysteroscopy
- Trial name
- NCT07672288
- Testing
- Evaluation score based on assessment tool
- Where
- 2 sites in Canada, Denmark
- Volunteers
- 24 people
- Sponsor
- Odense University Hospital
Uterine Hemorrhage, Cardiovascular Diseases
A Study on Abnormal Menstrual Bleeding in Chinese Women of Childbearing Age Taking Antithrombotic Drugs After Cardiovascular Surgery
This study aims to investigate uterine bleeding during menstruation in women taking antithrombotic medications after cardiac surgery.
- Conditions
- Uterine Hemorrhage, Cardiovascular Diseases, Antithrombotic Drugs
- Trial name
- NCT07870941
- Testing
- antithrombotic drugs
- Where
- China
- Volunteers
- 1,308 people
- Sponsor
- Shanghai Zhongshan Hospital
IUD, Abnormal Uterine Bleeding
Assessing Pain and Effectiveness of Carevix Device for IUD Insertions
The goal of this clinical trial is to evaluate patient-reported pain, bleeding, and device efficiency along with provider satisfaction and ease of use between IUD insertions using a suction cervical stabilizer (new device, FDA…
- Conditions
- IUD, Abnormal Uterine Bleeding, Pain, Cervical
- Trial name
- CARE (NCT07290517)
- Testing
- Carevix, Tenaculum
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Indiana University
Yiwu Cold Knife Technique for Multiple Endometrial Polyps
Yiwu Cold Knife Technique Versus Electrocision for Multiple Endometrial Polyps
# Clinical Trial Summary Template (Based on your endometrial polyp study) The goal of this clinical trial is to learn if cold knife hysteroscopic polypectomy (Yiwu procedure) works to treat multiple endometrial polyps in women.
- Trial name
- NCT07737301
- Testing
- Cold knife hysteroscopic polypectomy (Yiwu procedure), Electroresection hysteroscopic polypectomy
- Volunteers
- 850 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Menstrual Cycle, Menstrual Distress (Dysmenorrhea)
Menstrual Cycle Symptoms and Female Health
The complexity inherent to the hormonal fluctuations associated with the female menstrual cycle (MC) has contributed, from a methodological perspective in research, to the neglect of women's physiological characteristics and to…
- Conditions
- Menstrual Cycle, Menstrual Distress (Dysmenorrhea), Premenstrual Syndrome, Abnormal Uterine Bleeding (AUB)
- Trial name
- CICLOS (NCT07699224)
- Testing
- Prevalence
- Where
- Spain
- Volunteers
- 400 people
- Sponsor
- Universidad Rey Juan Carlos
Abnormal Uterine Bleeding (AUB), Ovulation Dysfunction
Clinical Efficacy And Safety of Dydrogesterone In The Treatment Of Abnormal Uterine Bleeding During Puberty
This multicenter prospective cohort study evaluates the clinical efficacy and safety of dydrogesterone versus drospirenone and ethinylestradiol in adolescents aged 10-19 years with abnormal uterine bleeding-ovulatory dysfunction…
- Trial name
- NCT07703488
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Guangdong Women and Children Hospital
Minimally Invasive Surgical Procedures, Abnormal Uterine Bleeding, Unspecified
Cyclobenzaprine for Postoperative Pain in Minimally Invasive Hysterectomy
Typical postoperative pain control after minimally invasive hysterectomy includes ibuprofen, acetaminophen, and a short course of narcotics.
- Conditions
- Minimally Invasive Surgical Procedures, Abnormal Uterine Bleeding, Unspecified, Adenomyosis of Uterus, Fibroid Uterus
- Trial name
- NCT07664956
- Testing
- Cyclobenzaprine
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Christiana Care Health Services
Endometriosis, Fibroids
Impact of Educational Videos on Pre-operative Anxiety
The goal of this clinical trial is to learn if educational videos can reduce pre-operative anxiety in patients undergoing minimally invasive gynecologic surgery.
- Conditions
- Endometriosis, Fibroids, Adenomyosis, Pelvic Pain
- Trial name
- NCT07740759
- Testing
- educational video
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- UConn Health
Iron Deficiency Anemia Treatment, Iron Deficiency
How Does Perimenopausal Menorrhagia Affect Women's Quality of Life and Cognitive Function?
The goal of this clinical trial is to investigate how iron status and heavy bleeding during the menopausal transition affect women's cognitive function and quality of life.
- Conditions
- Iron Deficiency Anemia Treatment, Iron Deficiency, Iron Deficiency (Without Anemia)
- Trial name
- MENO (NCT06798584)
- Testing
- FeoSol Original Iron Supplement Tablets, 21st Century Gelatin Capsules
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Purdue University
Cesarean Section Complications, Abnormal Uterine Bleeding
Combined Hystroscopic and Laparoscopic Repair of CS Scar Disorder
Combined hystroscopic and laparoscopic repair of symptomatic uterine Niche as new technique to maximize resolution of symptoms after niche repair with concomitant increase in RMT
- Trial name
- NCT07183501
- Testing
- Combined hystroscopic and laparoscopic repair
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Female Sexual Dysfunction, Endometrial Sampling
Assessment of Female Sexual Function Index (FSFI) Scores at 1 Month After Endometrial Sampling Performed Under Sedo-Analgesia or Local Anesthesia
Endometrial sampling is a commonly performed gynecological procedure used for the diagnosis of abnormal uterine bleeding and endometrial abnormalities.
- Conditions
- Female Sexual Dysfunction, Endometrial Sampling, Female Sexual Function Index (FSFI), Abnormal Uterine Bleeding, Unspecified
- Trial name
- FSFI-ENDO (NCT07628660)
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Abnormal Uterine Bleeding (AUB)
Pipelle Versus Manual Vacuum Aspiration Cannula for Endometrial Biopsy in Women With Abnormal Uterine Bleeding
women globally, often requiring endometrial tissue sampling for accurate evaluation and diagnosis. Traditional office-based sampling techniques like Pipelle are widely used, but the disposable instruments can be relatively…
- Trial name
- NCT07731581
- Testing
- Manual Vacuum Aspiration (MVA) Cannula, Pipelle Endometrial Suction Curette
- Volunteers
- 80 people
- Sponsor
- University of Health Sciences Lahore
Leiomyoma, Uterine, Benign Gynecological Disease
Deep Neuromuscular Blockade and a Low-Residue Diet for the Surgical Field in vNOTES Hysterectomy
vNOTES (vaginal natural orifice transluminal endoscopic surgery) hysterectomy is performed entirely through the vagina, with no abdominal incision.
- Conditions
- Leiomyoma, Uterine, Benign Gynecological Disease, Abnormal Uterine Bleeding (AUB), Uterine Prolapse
- Trial name
- vNOTES_NMBDIET (NCT07730970)
- Testing
- Deep Neuromuscular Blockade (NMB), Standard (moderate) neuromuscular blockade, Preoperative low-residue diet
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital