Clinical trials: Breast Cancer Prevention
Breast Cancer, Docetaxel Chemotherapy
A Trial of Evonail® Solution for Prevention or Treatment of Onycholysis
This study is a prospective randomized controlled study of EVONAIL® solution for prevention or treatment of onycholysis in patients with breast cancer receiving docetaxel chemotherapy.
- Trial name
- NCT02670603
- Testing
- EVONAIL® solution
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Breast Cancer
Diet and Breast Cancer Prevention Trial
This randomized controlled trial tests the hypothesis that a reduction in intake of dietary fat will reduce the incidence of breast cancer.
- Trial name
- NCT00148057
- Testing
- Low-fat diet
- Where
- Canada
- Volunteers
- 4,695 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Breast Carcinoma, Cervical Carcinoma
CATCH-UP Intervention in Increasing Cancer Screening and Prevention Care in Uninsured Patients at Community Health Centers
This randomized research trial studies the Community-based Health Information Technology (HIT) Tools for Cancer Screening and Health Insurance Promotion (CATCH-UP) intervention in increasing cancer screening and prevention care…
- Conditions
- Breast Carcinoma, Cervical Carcinoma, Colorectal Carcinoma, Health Status Unknown
- Trial name
- NCT02355262
- Testing
- Informational Intervention
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Degradation of Top2b and Top2a in Human by Dexrazoxane, Time Course and Degradation of Top2b in Human by Dexrazoxane
Prevention of Heart Failure Induced by Doxorubicin With Early Administration of Dexrazoxane
The purpose of this research study is to determine whether early administration of Dexrazoxane prevents Doxorubicin induced cardiotoxicity.
- Conditions
- Degradation of Top2b and Top2a in Human by Dexrazoxane, Time Course and Degradation of Top2b in Human by Dexrazoxane, Effects of Dexrazoxane on Healthy Human
- Trial name
- PHOENIX1 (NCT03930680)
- Testing
- Dexrazoxane
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Breast Cancer, Prevention
"Effectiveness of Community Health Workers in Breast Cancer Prevention in Jumla: a Cluster Randomized Trials
Breast cancer is the second most prevalent cancer among Nepali females, accounting for 17.1% of cases and 7.7% of female cancer-related deaths.
- Trial name
- NCT06869759
- Testing
- Implementation strategy - Health Promotion and Education-based intervention
- Where
- Nepal
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Karnali Academy of Health Sciences
Breast Cancer
Breast Stem Cells in Women at Average Risk and Increased Risk for Breast Cancer
Background: Research suggests that breast cancers may arise from a population of stem cells in the normal mammary gland that produce clones of cancer cells.
- Trial name
- NCT00923377
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Breast Cancer
IH636 Grape Seed Extract in Preventing Breast Cancer in Postmenopausal Women at Risk of Developing Breast Cancer
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of IH636 grape seed extract may prevent breast cancer.
- Trial name
- NCT00100893
- Testing
- IH636 grape seed proanthocyanidin extract
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Breast Cancer
Implementing Polygenic Risk Scores for Breast Cancer Prevention: a Feasibility Study
This single-arm interventional feasibility study will evaluate whether integrating polygenic risk scores (PRS) into the CanRisk model can improve breast cancer risk prediction and personalized prevention in women at risk of…
- Trial name
- MIG (NCT06922708)
- Testing
- Clinical pathway for breast cancer prevention based on PRS-integrated CanRisk assessment
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Breast Cancer
DAMES: Daughters And MothErS Against Breast Cancer
Primary Aim: -To explore the feasibility and acceptability of two distinctly different tailored, home-based diet and exercise interventions (one that relies on a partner-assisted, team-based approach that emphasizes the…
- Trial name
- NCT00630591
- Testing
- Standardized Materials Group, Independent Tailored Intervention, Partner-Assisted Tailored Intervention
- Where
- 2 sites in United States
- Volunteers
- 482 people, healthy volunteers welcome
- Sponsor
- Duke University
Breast Cancer Screening, Breast Carcinoma in Situ
Women Informed to Screen Depending on Measures of Risk (Wisdom Study)
Most physicians still use a one-size-fits-all approach to breast screening in which all women, regardless of their personal history, family history or genetics (except BReast CAncer gene (BRCA) carriers) are recommended to have…
- Conditions
- Breast Cancer Screening, Breast Carcinoma in Situ, Breast Cancer
- Trial name
- WISDOM (NCT02620852)
- Testing
- Complete a health questionnaire, Provide a saliva sample for genetic testing, Screening advice based on a comprehensive risk assessment
- Where
- 11 sites in United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Breast Neoplasms
Breast Cancer and Exercise Trial in Alberta
The Breast Cancer and Exercise Trial (BETA Trial) is a randomized controlled trial aimed at understanding what dose (or volume) of exercise will best reduce the risk for breast cancer, particularly among women who are between the…
- Trial name
- BETA (NCT01435005)
- Testing
- Moderate Volume, High Volume
- Where
- 2 sites in Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- AHS Cancer Control Alberta
BRCA1 Mutation, Breast Cancer
Studying the Effect of Denosumab on Preventing Breast Cancer in Women With a BRCA1 Germline Mutation
This phase III trial compares denosumab to placebo for the prevention of breast cancer in women with a BRCA1 germline mutation. A germline mutation is an inherited gene change which, in the BRCA1 gene, is associated with an…
- Conditions
- BRCA1 Mutation, Breast Cancer, Breast Diseases, Breast Neoplasms
- Trial name
- BRCA-P (NCT04711109)
- Testing
- Denosumab, Quality-of-Life Assessment
- Where
- 47 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Alliance for Clinical Trials in Oncology
Obesity, Colorectal Cancer
Prevention of Obesity-related Cancers: Setting up of a Multi-Cancer Education and Prevention Program in Hong Kong
Obesity could increase the risk of many chronic diseases, including hypertension, cardiovascular diseases, high lipid level, diabetes, stroke, endometrial cancer and certain types of cancer which could benefit by secondary…
- Conditions
- Obesity, Colorectal Cancer, Prostate Cancer, Breast Cancer
- Trial name
- NCT04034953
- Testing
- Faecal Immunochemical Test, Prostate-Specific Antigen Test, Mammogram
- Where
- Hong Kong
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Arthralgia, Breast Neoplasms
Omega-3 Supplementation in Prevention of Aromatase Inhibitor-Induced Toxicity in Patients With Stage I-III Breast Cancer
This clinical trial studies the use of omega-3 fatty acid supplementation in preventing aromatase inhibitor-induced toxicity in patients with stage I-III breast cancer.
- Trial name
- NCT02831582
- Testing
- Omega-3 Fatty Acid
- Where
- 3 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Breast Cancer, Cervical Cancer
Salud en Mis Manos - Breast and Cervical Cancer Prevention and Early Detection - Expansion 2
The purpose of this study is to increase early detection and prevention of breast and cervical cancer through education and navigation and to increase breast and cervical cancer screening and Human Papillomavirus (HPV)…
- Trial name
- SEMM2 (NCT06082882)
- Testing
- Education, Navigation to clinic
- Where
- United States
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Breast Cancer
A Multi-Modality Surveillance Program for Women at High Risk for Breast Cancer
This study is aimed to establish a registry of women undergoing intensive surveillance for the early detection of breast cancer in high-risk women.
- Trial name
- CAPS (NCT03729115)
- Testing
- Magnetic Resonance Imaging (MRI)
- Where
- 3 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Electroacupuncture, Olanzapine-contained Four-drug Antiemetic
Electroacupuncture for the Prevention of Chemotherapy-induced Nausea and Vomiting in Patients With Breast Cancer
This randomized controlled phase III trial aims to evaluate the use of electroacupuncture in combination with olanzapine-containing standard quadruple antiemetic drugs for the treatment of nausea and vomiting induced by highly…
- Conditions
- Electroacupuncture, Olanzapine-contained Four-drug Antiemetic, Nausea and Vomiting
- Trial name
- NCT06200168
- Testing
- Electroacupuncture, Standard antiemetic treatment
- Where
- China
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Jiuda Zhao
Breast Cancer Female
The Effect of Breast Cancer Prevention Journey Program
The aim of this quasi-experimental study is to determine the effect of the "Breast Cancer Prevention Journey Program" on health beliefs about breast cancer in women over 40 years of age who have never had a mammogram before.
- Trial name
- NCT06395896
- Testing
- Breast Cancer Prevention Journey Program Group, Routine Cancer Screening Program Group
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nurbanu Odacı
Breast Neoplasm
Study of Web-based Decision Aids for Increasing Breast Cancer Chemoprevention in the Primary Care Setting
The purpose of this randomized controlled trial (RCT) is to evaluate a decision support website (RealRisks) designed to inform patients about breast cancer prevention options.
- Trial name
- NCT03069742
- Testing
- RealRisks, BNAV
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Columbia University
Cancer, Breast, Cancer, Colon
Enhancing Cancer Prevention and Control Pathways-Native Health Initiative
There are continued disparities in cancer incidence, mortality, and survival between American Indians (AIs) and Whites on cancers responsive to early screening (i.e., breast, colorectal, and cervical) in the US.
- Conditions
- Cancer, Breast, Cancer, Colon, Cancer, Cervix
- Trial name
- NCT04259762
- Testing
- Aim 8 (INT, Pilot Test): Breast, Colorectal, and Cervical Cancer Screening Cognitive-Behavioral Interventions
- Where
- United States
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- New Mexico Cancer Research Alliance