Clinical trials: Breast Cancer Prevention
Breast Cancer
Breast Cancer - Anti-Progestin Prevention Study 1
The primary objective of this study is to determine the effects of the antiprogestin ulipristal acetate (UA) on the epithelial and stromal compartments of the normal breast in women at increased risk of breast cancer (BC) and to…
- Trial name
- BC-APPS1 (NCT02408770)
- Testing
- ulipristal acetate
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Breast Cancer Prevention, Colorectal Cancer Prevention
PR-CEAL: Community Outreach Engagement Group
The United States Preventive Services Task Force (USPSTF) recommends regular screenings for breast, cervical, and colorectal cancer.
- Conditions
- Breast Cancer Prevention, Colorectal Cancer Prevention, Cervical Cancer Prevention
- Trial name
- PR-CEAL:COEG (NCT07214051)
- Testing
- Cancer Screening Information
- Where
- Puerto Rico
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico Comprehensive Cancer Center
Breast Cancer, Cervical Cancer
Kin KeeperSM: Reducing Disparities Through Cancer Literacy and Screening
1) To determine if the Kin KeeperSM Cancer Prevention Intervention increases first time and appropriately timed breast cancer screening rates among Black, Latina and Arab women; 2) To determine if the Kin KeeperSM Cancer…
- Trial name
- KinKeeper (NCT01910350)
- Testing
- Kin KeeperSM Cancer Prevention Intervention, Standard of care
- Where
- United States
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Breast Cancer, Mammographic Density
The Malaysian Soy and Mammographic Density Study
Globally, breast cancer is the most common cancer and the main cause of deaths due to cancer. This is attributed to changes in reproductive habits as well as an increasingly sedentary lifestyle, with low physical activity and…
- Trial name
- MiSo (NCT03686098)
- Testing
- Dietary soy, Soy Supplement
- Where
- Malaysia
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Cancer Research Malaysia
Breast Cancer
Nutritional Supplements and Hormonal Manipulations for Breast Cancer Prevention
The overall hypothesis is that the combination of a low dose of the antiestrogen Raloxifene with omega-3 fatty acids will exert a synergistic breast cancer chemopreventive effect due to the crosstalk of their downstream cellular…
- Trial name
- NCT00723398
- Testing
- Lovaza 4gm oral, Raloxifene 60 Mg Oral Tablet, Raloxifene 30 Mg Oral Tablet
- Where
- United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Breast Cancer Prevention
Active Mammography and Counseling
The Puerto Rico Community Engagement Alliance (PR-CEAL) is an NIH-funded initiative which aims to improve health literacy and healthcare access across Puerto Rico.
- Trial name
- MAMO (NCT07238088)
- Testing
- Individual Education, Community Navigation, Healthcare Providers Educational Intervention
- Where
- Puerto Rico
- Volunteers
- 1,020 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico Comprehensive Cancer Center
Breast Neoplasms Diagnosis
Breast Cancer Risk Assessment in Night Shift Workers - Implementation of a Personalized Consultation
This study evaluates adherence to a personalized prevention plan in female night shift workers at increased risk of breast cancer.
- Trial name
- NIGHT-SCAN (NCT07630935)
- Testing
- Personalized Prevention Plan
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breast Cancer
Automated Tele Counseling for Screening Mammography
The purpose and aim of this study is to test the use of a computer-based, automated telecommunications system and its effectiveness in increasing the rates of regular screening mammography among women ages 50-74.
- Trial name
- NCT00247013
- Testing
- Breast Cancer Screening Compliance
- Where
- United States
- Volunteers
- 2,120 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Chemotherapy Induced Peripheral Neuropathy (CIPN)
Continuous Controlled Cooling for Prevention of Chemotherapy-Induced Peripheral Neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of certain types of chemotherapy and can cause numbness, tingling, pain, and other symptoms in the hands and feet.
- Trial name
- COOL-tax (NCT07917026)
- Testing
- Continuous Controlled Cooling of the Hands and Feet
- Where
- Sweden
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Cervical Cancer, Breast Cancer
Sexual Health Empowerment for Women's Health
The purpose of this study is to expand the reach of an existing cervical cancer literacy and prevention intervention- the Sexual Health Empowerment (SHE) Project .
- Conditions
- Cervical Cancer, Breast Cancer, Contraceptive Usage, Sexually Transmitted Diseases
- Trial name
- SHE-WOMEN (NCT03984695)
- Testing
- SHE-WOMEN
- Where
- United States
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Breast Carcinoma
Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer
This phase II trial tests whether low-dose aspirin can affect markers of inflammation in postpartum (after childbirth) women planning to have a breast biopsy.
- Trial name
- NCT05557877
- Testing
- Biospecimen Collection, Low-Dose Aspirin, Questionnaire Administration
- Where
- 5 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Body Image Disorder
Prevention of Body Image Disorder by Nurse Intervention on the Patient and Family Prior to Breast and Colon Surgery
This is a non-blinded, randomized, controlled clinical trial consisting of 64 participants, which aims to assess the effectiveness of a nursing intervention for family members and patients prior to surgery to prevent body image…
- Trial name
- NCT03726801
- Testing
- HEALTH EDUCATION
- Where
- Spain
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Cancer
Clinical Validation of the Role of microRNA Binding Site Mutations in Cancer Risk, Prevention and Treatment
The investigators will recruit and enroll individuals that may have the KRAS-variant or other microRNA binding site mutations to join registry studies.
- Trial name
- NCT02253251
- Testing
- KRAS-variant and microRNA binding site mutation testing
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- MiraKind
Cancer Risk, Cancer Predisposition Syndrome
InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer
This research study is creating a way to collect and store specimens and information from participants who may be at an increased risk of developing cancer, or has been diagnosed with an early phase of a cancer or a family member…
- Conditions
- Cancer Risk, Cancer Predisposition Syndrome, Hereditary Cancer Prediction, Childhood Cancer Survivors
- Trial name
- NCT05463796
- Testing
- Samples
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer
Using Technology to Improve Physical Activity Levels Among Postmenopausal Women (The Active & Aware Study)
Women who are overweight or do not exercise are at higher risk for breast cancer after menopause. This study will test a new electronic device that measures the body's movement and works alongside a website to help women increase…
- Trial name
- NCT01837147
- Testing
- Technology-Based Physical Activity Promotion, Pedometer Intervention
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Breast Cancer
Topical Doxepin for Radiation-induced Dermatitis
Radiation dermatitis is one of the most common side effects of radiotherapy approximately occurring in about 95% of patients receiving radiotherapy .
- Trial name
- NCT02447211
- Testing
- Doxepin cream 5%
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Healthy
Flaxseed Intervention Study to Assess Sex Hormone Levels Among Post-Menopausal Women
The purpose of this study is to understand whether consuming flaxseed for approximately 50 days may beneficially affect the level of certain hormones in the blood thought to be involved in the development of breast cancer.
- Trial name
- NCT02501031
- Testing
- Ground flaxseed
- Where
- Canada
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Cancer Care Ontario
Breast Neoplasms
Know Your Risk: Assessment at Screening for Breast Cancer - Pilot Study
The purpose of this pilot study is to evaluate a decision support website (RealRisks) designed to inform patients about breast cancer chemoprevention.
- Trial name
- KYRAS (NCT02954900)
- Testing
- RealRisks, BNAV
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Columbia University
Metastatic HR+/HER2- Breast Cancer
Rash & Diarrhea Prophylaxis With Capivasertib
This is a randomized, multicenter, phase II clinical trial evaluating prophylactic strategies to mitigate common toxicities associated with capivasertib in combination with fulvestrant in participants with hormone…
- Trial name
- SAFE-CAP (NCT07426822)
- Testing
- Capivasertib, Loperamide, Fulvestrant
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Maryam Lustberg
Osteoporosis
Danish Osteoporosis Prevention Study
Hypothesis: Use of hormone replacement therapy (HRT) decreases the incidence of fractures in early postmenopausal women. The project was initiated in 1990, and the inclusion ended in 1993.
- Trial name
- NCT00252408
- Testing
- Hormone replacement therapy
- Where
- Denmark
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus