Clinical trials: Breast Cancer Risk Factors
Healthy, Premenopausal Period
Effects of Omega-3 Fatty Acids on Risk Factors for Breast Cancer in Pre-menopausal Women
Healthy premenopausal women were enrolled in a diet intervention study that examined the effect of a combination EPA/DHA supplement on risk factors associated with breast cancer.
- Trial name
- NCT02816125
- Testing
- omega-3 fatty acid
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Breast Cancer, Breast Neoplasms
A Study of Breast Cancer Risk Factors and Outcomes of People in Florida
The purpose of this study is to understand why different people have different risks and outcomes for breast cancer and non-breast cancer.
- Conditions
- Breast Cancer, Breast Neoplasms, Breast Diseases
- Trial name
- NCT06780176
- Testing
- Biospecimen Collection, Surgical Tissue Collection, Survey Collection
- Where
- 3 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Invasive Breast Cancer
Identification of Novel Genetic Factors That Contribute to Risk for Breast Cancer
The purpose of this study is to identify novel genetic factors which distinguish breast cancer in younger women compared to older women.
- Trial name
- NCT00276120
- Where
- United States
- Volunteers
- 4,385 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Breast Cancer
Whole Body Vibration Training and Breast Cancer Risk Factors
study aim is to determine the effect of whole body vibration training (WBVT) on body mass index, serum prolactin concentration as a risk factors for breast cancer and severity of hot flashes in obese postmenopausal women.
- Trial name
- NCT04708093
- Testing
- whole body vibration training
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Breast Cancer, Obesity
Effects of Mediterranean Diet and Naltrexone/Bupropion Treatment in Obese Breast Cancer Patients
Obesity among breast cancer survivors is known to be associated with recurrence and other co-morbidities. However, there have been no studies on weight reduction program combining diet and anti-obesity drug for obese breast…
- Conditions
- Breast Cancer, Obesity, Overweight
- Trial name
- NCT03581630
- Testing
- naltrexone/bupropion, Mediterranean Diet
- Where
- South Korea
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Cardiovascular Diseases
Reexamining Her Cardiovascular Risk - Ottawa WomeN's Longitudinal Cohort Study
The full HER CROWN will be a prospective cohort study to propose a novel, women-specific cardiovascular risk score/ algorithm in the prediction of hard cardiovascular outcomes (myocardial infarction, unstable angina, coronary…
- Trial name
- HER-CROWN (NCT05632601)
- Testing
- PET scan
- Where
- Canada
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Breast Cancer Females
Short-term Impacts of Endocrine Therapy on Cardiovascular and Brain Health Outcomes in Breast Cancer
Aromatase inhibitors are the most used endocrine therapy for hormone-positive breast cancer. While there is a clear linear relationship between the duration of aromatase inhibitor use and the cumulative incidence of…
- Trial name
- STRIVE (Acute) (NCT06781762)
- Testing
- N/A (Usual Care)
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Breast Cancer Prevention
MELIORA Virtual Coach Intervention for Breast Cancer Prevention
Breast cancer (BC) is the most commonly diagnosed cancer in women worldwide, with early-onset cases increasing due to genetic and lifestyle factors.
- Trial name
- MELIORA (NCT07200427)
- Testing
- MELIORA Virtual Coach Intervention, Control (generic advice)
- Where
- 7 sites in Greece, Lithuania and 2 more
- Volunteers
- 2,080 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Weight Loss, Breast Cancer Risk Factors
Addressing Modifiable Breast Cancer Risk Factors With Project CONECT
The objective of this protocol is to adapt and pilot test an existing lifestyle modification intervention for weight loss for women with overweight or obesity who have had a recent false positive mammography screen.
- Trial name
- NCT02871388
- Testing
- CONECT
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Metabolic Syndrome as Breast Cancer Risk Factor
Metabolic Syndrome as Modifiable Risk Factor for Breast Cancer
Healthy women and women with breast cancer have been enrolled in our nested case-control study between 2008 and 2009 in order to evaluate the association between metabolic syndrome and breast cancer, analyzing anthropometric…
- Trial name
- NCT01172886
- Where
- Italy
- Volunteers
- 777 people, healthy volunteers welcome
- Sponsor
- Sbarro Health Research Organization
Health Knowledge, Attitudes, Practice, Alcohol Consumption
Increasing Knowledge of Alcohol as a Risk Factor for Breast Cancer Among Women Attending Breast Screening Services
Alcohol is a major modifiable risk factor for breast cancer in women, yet this is not widely understood by health practitioners or policy makers, let alone the general population.
- Trial name
- Health4Her (NCT04715516)
- Testing
- alcohol brief intervention, lifestyle health promotion
- Where
- Australia
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- Turning Point
Breast Neoplasm, Primary Prevention
Project Breast47: Effect of an Educational Intervention
Breast cancer is the most frequently diagnosed malignant tumor in women. In 2018, in Spain, the estimated incidence was 101/100,000 women.
- Conditions
- Breast Neoplasm, Primary Prevention, Risk Factors, Telemedicine
- Trial name
- Breast47 (NCT05267171)
- Testing
- Web access
- Where
- Spain
- Volunteers
- 451 people, healthy volunteers welcome
- Sponsor
- University of Oviedo
Obesity, Breast Cancer Risk
Effects of Tirzepatide on Blood, Imaging and Breast Tissue Biomarkers
Evaluation of biomarkers for risk of developing breast cancer in women with obesity who are using tirzepatide to achieve weight loss.
- Trial name
- NCT06485089
- Testing
- tirzepatide
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Breast Cancer
Nutrition-Related Biomarkers in Predicting Breast Cancer Risk in Women
RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about nutrition-related changes that identify biomarkers related to cancer.
- Trial name
- NCT00900367
- Testing
- high performance liquid chromatography, laboratory biomarker analysis, spectroscopy
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Obesity, Overweight
Choose to Lose for Women-Weight Loss to Reduce Breast Cancer Risk Factors
This study is investigating the changes in specific hormone levels in women age 30-45 after a 12 week weight loss intervention.
- Trial name
- CTL (NCT01096901)
- Testing
- Behavioral Weight loss
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Breast Cancer Females
Chronic Impacts of Endocrine Therapy on Cardiovascular and Brain Health Outcomes in Breast Cancer
Aromatase inhibitors are the most used endocrine therapy for hormone-positive breast cancer. Despite the evidence that aromatase inhibitor therapy is associated with increased risk of cardiovascular events, potentially related to…
- Trial name
- STRIVE-Chronic (NCT06776458)
- Testing
- N/A - Usual Care
- Where
- Canada
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Colorectal Cancer, Breast Cancer
Case Control Study to Identify Modifiable Risk Factors for Colorectal and Breast Cancer in Nigeria
This project is a case-control study which seeks to identify modifiable risk factors for breast and colorectal cancer in Nigeria.
- Trial name
- NCT05044689
- Testing
- Questionnaire, Bioimpedance/Body Composition Unit
- Where
- Nigeria
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Obafemi Awolowo University Teaching Hospital
Breast Cancer
Genes and Other Risk Factors for Second Primary Breast Cancer in Women With Breast Cancer and Their Female Family Members and Friends
RATIONALE: Studying samples of blood, urine, and tumor tissue in the laboratory from patients with cancer and their female relatives and friends may help doctors learn more about changes that occur in DNA and identify biomarkers…
- Trial name
- NCT00896818
- Testing
- DNA analysis, genetic linkage analysis, loss of heterozygosity analysis
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cancer Research UK
Observational Study
The Association of Hormonal Intake and Demographic Factors With Breast Cancer Risk. An Egyptian Case-controlled Study
The aim of the current study is to investigate the association between hormonal intake, occupational and demographic factors, and the risk of breast cancer (BC) among Egyptian females.
- Trial name
- NCT05135013
- Testing
- Dydrogesterone Tablets, Norethisterone acetate, Ethinyl estradiol, Drospirenone and ethinyl estradiol
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- NewGiza University
Breast Cancer
The Sister Study: Genetic and Environmental Risk Factors for Breast Cancer
The Sister Study is prospectively examining environmental and familial risk factors for breast cancer and other diseases in a cohort of 50,884 sisters of women who have had breast cancer.
- Trial name
- NCT00047970
- Where
- United States
- Volunteers
- 50,884 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)