Clinical trials: Breast Cancer Surgery Pain
Breast Cancer Females
Auricular Acupressure for Perioperative Anxiety and Pain in Therapeutic Breast Surgery (ROSA)
This randomized, controlled, single-center trial investigates the effects of auricular acupressure, administered according to the National Acupuncture Detoxification Association (NADA) protocol, on perioperative anxiety and pain…
- Trial name
- ROSA (NCT07423039)
- Testing
- Auricular Acupressure NADA
- Where
- Germany
- Volunteers
- 66 people
- Sponsor
- Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF)
Bone Metastases
ExAblate Conformal Bone System Treatment of Metastatic Bone Tumors for the Palliation of Pain
A study to evaluate the safety and initial effectiveness of the ExAblate 2100 Conformal Bone System in the treatment of pain resulting from metastatic bone tumors.
- Trial name
- NCT00981578
- Testing
- ExAblate 2100
- Where
- 5 sites in United States
- Volunteers
- 37 people
- Sponsor
- InSightec
Post-mastectomy Pain Syndrome
The Efficacy of Tianeptine Versus Pregabalin on Acute and Chronic Post Mastectomy Pain After Breast Cancer Surgery.
Breast cancer is the most common malignancy among females. Nearly 40% of breast surgery patients experience moderate to severe acute postoperative pain, with severe pain persisting for more than 6 months in almost 20-50% of…
- Trial name
- NCT05935059
- Testing
- Pregabalin, Tianeptine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Breast Cancer, Surgery
Polyamine-free Diet to Prevent Post Surgery Hyperalgesia
After surgery, sensitization and hyperexcitability of central nervous system result in acute and long lasting postoperative pain.
- Trial name
- PoLyDOL (NCT00304850)
- Testing
- polyamine-free diet
- Where
- 5 sites in France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Bordeaux
Persistent Pain After Breast Cancer Surgery
Ultrasound Guided Pectoral Nerves Blockade for Persistent Pain After Breast Cancer Surgery
This is a pilot study of the pectoral nerves block (PECS) in patients with persistent pain after breast cancer surgery.
- Trial name
- PPBCS (NCT02349581)
- Testing
- PECS block, Bupivacaine
- Where
- Denmark
- Volunteers
- 6 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Malignant Neoplasm of Breast
MIRs03: Paravertebral Block With Ropivacaine Before Breast Cancer Surgery
Compare the effect of paravertebral block (PVB) with Ropivacaine or placebo on the incidence of chronic pain 3 months after breast cancer surgery.
- Trial name
- MIRs03 (NCT02408393)
- Testing
- Saline, Ropivacaine
- Where
- 6 sites in France
- Volunteers
- 380 people
- Sponsor
- Institut Curie
Postoperative Pain, Breast Cancer Surgery
Postoperative Pain, Central Sensitization, and Sleep Quality in Breast Cancer Surgery Patients
This prospective observational study aims to investigate whether preoperative central sensitization and sleep quality are associated with acute postoperative pain levels in patients undergoing breast cancer surgery.
- Conditions
- Postoperative Pain, Breast Cancer Surgery, Central Sensitization, Sleep Quality
- Trial name
- NCT07077421
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Istanbul University - Cerrahpasa
Post-mastectomy Pain Syndrome, Chronic Post-surgical Pain
Perioperative Pregabalin and Lidocaine to Reduce Chronic Breast Cancer Pain
Breast tissue and the areas surrounding the breast contain many small to medium-sized nerves. During surgery on the breast, these nerves can be inadvertently cut or damaged.
- Trial name
- PLAN (NCT02240199)
- Testing
- Intraoperative Intravenous Lidocaine Infusion, Perioperative Pregabalin
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- McMaster University
Breast Cancer
Liposomal Bupivacaine Vs Bupivacaine with Dexmedetomidine in Erector Spinae Plane Blocks for Mastectomies
Perform a comparison of effective pain relief duration between liposomal bupivacaine and dexmedetomidine when added to bupivacaine in a block for mastectomy for cancer surgery.
- Trial name
- NCT06252662
- Testing
- Dexmedetomidine, Liposomal bupivacaine
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, Portsmouth
Pain, Postoperative, Disability Physical
Effects of Interpectoral-Pectoserratus Plane Block After Breast Cancer Surgery
The aim of this study: It was aimed to observe the effects of intraoperative and preoperative PECS II block on postoperative pain, amount of analgesic use and shoulder joint range of motion in patients who underwent breast cancer…
- Conditions
- Pain, Postoperative, Disability Physical, Quality of Life
- Trial name
- NCT05568589
- Testing
- Preoperative Interpectoral - Pectoserratus Plane Block, Intraoperative Interpectoral - Pectoserratus Plane Block, Non Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Izmir Bakircay University
Cancer Breast, Hypovitaminosis D
Influence of Preoperative Vitamin D Level on Postoperative Pain in Breast Cancer Surgery Patients
Vitamin D deficiency is a general problem that vigorously affects human health . Breast cancer is the most frequently diagnosed life-threatening cancer in women and the leading cause of cancer death among women.Vitamin D…
- Trial name
- NCT06551688
- Testing
- Serum 25(OH)D level
- Where
- Egypt
- Volunteers
- 184 people
- Sponsor
- Fayoum University
Pain, Pain Management
Evaluating The Efficacy Of Pecs II Blockade Compared To Local Anesthetic Infiltration In Controlling Postoperative Pain In Patients Undergoing Oncologic Breast Surgery Under Opioid Free/Sparing Anesthesia.
Breast cancer is the malignant neoplasm with the highest incidence in women in Brazil, with the exception of non-melanoma skin tumors.
- Conditions
- Pain, Pain Management, Anesthesia
- Trial name
- pain (NCT06889870)
- Testing
- Pectoral Nerve Block, Local Anesthesia
- Where
- Brazil
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas de Minas Gerais
Astrocytoma, Brain Cancer
Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S
This is a multi-center, open-label, dose escalation study to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, and maximum tolerated dose (MTD) of QBS10072S in patients with advanced or metastatic cancers…
- Conditions
- Astrocytoma, Brain Cancer, Brain Metastases, Bladder Cancer
- Trial name
- NCT04430842
- Testing
- QBS10072S
- Where
- 2 sites in Australia
- Volunteers
- 15 people
- Sponsor
- Quadriga Biosciences, Inc.
Thyroid Nodule
Mini-flap BABA (Bilateral Axillo-breast Approach) Robotic Thyroidectomy is Safe
In this study, a randomized controlled study was conducted between two groups of 40 recipients of conventional flap during BABA robotic-thyroidectomy and 40 recipients of Mini-flap method during BABA robotic-thyroidectomy.
- Trial name
- NCT05216718
- Testing
- Mini-flap, Conventional flap
- Where
- South Korea
- Volunteers
- 82 people
- Sponsor
- Inje University
Breast Cancer
Regional Anesthesia for Breast Surgery
Patients scheduled for mastecotmy will be randomized to receive either an ultrasound-guided double space paravertebral block or a PECSII + parasternal block.
- Trial name
- NCT03941223
- Testing
- PECSII and paravertebral blocks
- Where
- Italy
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Breast Cancer, Survivorship
Dance Study for Post-surgical Pain in Breast Cancer Survivors
The purpose of this study is to examine how a 12-week, virtual dance program may improve pain and quality of life in participants with persistent post-surgical pain, or PPSP, following mastectomy or lumpectomy.
- Conditions
- Breast Cancer, Survivorship, Pain, Postoperative
- Trial name
- NCT06758102
- Testing
- Dance Program
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer, Chronic Pain
Evaluation And Risk Assessment For Persistent Postsurgical Pain After Breast Surgery
Pre-existing pain and severe postoperative pain are predictors of persistent pain after surgery, but a complete understanding on the development of persistent pain is still lacking.
- Conditions
- Breast Cancer, Chronic Pain, Acute Pain, Depression, Anxiety
- Trial name
- B-CAPP (NCT03408717)
- Testing
- Questionnaires, Mechanical Temporal Summation assessment, Pain threshold assessment
- Where
- 2 sites in United States, Singapore
- Volunteers
- 220 people
- Sponsor
- KK Women's and Children's Hospital
Breast Cancer, Anesthesia
Opioid-free Anaesthesia in Breast Cancer Surgery
Background: Various analgesic modalities are adopted for perioperative analgesia in breast cancer surgeries. Opioid-free and opioid-sparing techniques are gaining popularity due to the lack of opioid-dependent undesirable…
- Conditions
- Breast Cancer, Anesthesia, Pain, Postoperative, Pain, Chronic
- Trial name
- NCT06404983
- Testing
- Opioid Free Anaesthesia (OFA), Conventional General Anaesthesia (CGA)
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- University of Ioannina
Breast Cancer
Impact of Regional Anesthesia on Chronic Post-operative Pain
Approximately 55,000 cases of breast cancer are diagnosed in Italy every year and the first-line therapy for carcinoma in situ, stage I, II and IIIA is surgical removal of the tumour.
- Trial name
- IRACPoP (NCT05876390)
- Testing
- Breast surgery, analgesia
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- Niguarda Hospital
Breast Cancer Patient
Evaluation in the Treatment of Neuropathic Pain Post Breast Surgery
Breast cancer is the most common cancer in women in Europe. Therefore, breast cancer has become a chronic disease and patients need to learn to live with it as well as with the adverse effects related to the disease itself or to…
- Trial name
- CAPTRANE (NCT03794388)
- Testing
- Capsaicin, Pregabalin
- Where
- 11 sites in France
- Volunteers
- 140 people
- Sponsor
- Institut Cancerologie de l'Ouest