Clinical trials: Breast Cancer Surgery Pain
Chronic Post-Procedural Pain, Breast Cancer
Evaluation of Persistent Postsurgical Pain After Breast Surgery With a Pectoral Nerves Block (Pecs) Type II
Background and objectives The Pectoral Nerves Block (Pecs) Type II is a regional anesthesia technique that provides post-surgical pain relief for patients undergoing breast surgery.
- Trial name
- NCT03116048
- Testing
- Chronic pain evaluation
- Where
- Belgium
- Volunteers
- 121 people
- Sponsor
- GZA Ziekenhuizen Campus Sint-Augustinus
Breast Cancer, Postoperative Pain, Acute
Rhomboid Intercostal Plane Block on Chronic Pain Incidence and Acute Pain Scores After Mastectomy
Rhomboid intercostal block is used to block lateral cutaneous branches of intercostal nerves between T3 and T9 dermatomes. RIB has been reported to be successful in attenuating acute pain following breast surgeries.
- Conditions
- Breast Cancer, Postoperative Pain, Acute, Postoperative Pain, Chronic, Neuropathic Pain
- Trial name
- NCT06019325
- Testing
- RIB
- Where
- Turkey (Türkiye)
- Volunteers
- 254 people
- Sponsor
- Muğla Sıtkı Koçman University
Breast Cancer, Chronic Pain
Reducing Pain and Disability After Breast Cancer Surgery
The purpose of this study is to determine if the combination of thoracic paravertebral block and multimodal analgesia will decrease chronic pain and arm morbidity in patients undergoing breast cancer surgery with lymph node…
- Trial name
- RELIeF (NCT01089933)
- Testing
- Thoracic Paravertebral Block (TPVB), Local Anesthetic
- Where
- Canada
- Volunteers
- 129 people
- Sponsor
- Ottawa Hospital Research Institute
Breast Cancer, Anxiety
Self Hypnotic Relaxation As An Adjunct To Local Anesthesia During Large Core Breast Biopsy
Percutaneous large core image-guided breast biopsy is a well established tool in diagnosing breast cancer, but the associated anxiety and pain can tax the coping mechanism of even well functioning individuals.
- Conditions
- Breast Cancer, Anxiety, Pain
- Trial name
- NCT00122369
- Testing
- Self-hypnotic Relaxation, Empathic Attention
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Beth Israel Deaconess Medical Center
Breast Cancer, Postoperative Pain
Single vs Multiple Injection Intertransverse Process Block in Breast Cancer Surgery
This randomized clinical trial aims to evaluate and compare the analgesic efficacy of single Intertransverse Process Block (ITP) and multiple Intertransverse Process Block (ITP) in patients undergoing Breast Cancer Surgery.
- Conditions
- Breast Cancer, Postoperative Pain, Mastectomy, Regional Anaesthesia
- Trial name
- NCT07763756
- Testing
- Multiple Level Intertransverse Process Block, Single Level Intertransverse Process Block
- Volunteers
- 60 people
- Sponsor
- Antalya City Hospital
Pain, Neuropathic Pain
Nerveblocks for Persistent Pain After Breast Cancer Surgery
Persistent pain after breast cancer surgery (PPBCS) affects 25-60% of breast cancer survivors and nerve damage has been implicated as the cause of this neuropathic pain condition.
- Conditions
- Pain, Neuropathic Pain, Breast Cancer
- Trial name
- NCT02336529
- Testing
- Bupivacaine, NaCl
- Volunteers
- 48 people
- Sponsor
- Kenneth Geving Andersen
Breast Cancer, Breast Cancer Female
Long-term Outcomes of Lidocaine Infusions for Post-Operative Pain (LOLIPOP) Trial
The LOLIPOP Trial is a large (n=4,300 patients) pragmatic, international, multicentre, prospective, randomised, double blind, placebo-controlled, parallel assessment, safety and effectiveness superiority study.
- Conditions
- Breast Cancer, Breast Cancer Female, Breast Conserving Surgery, Mastectomy
- Trial name
- LOLIPOP (NCT05072314)
- Testing
- lidocaine 2% and 10%
- Where
- 49 sites in Australia, Hong Kong and 2 more
- Volunteers
- 4,300 people
- Sponsor
- Monash University
Postoperative Pain
Ultrasound Guided Costotransverse Block for Breast Cancer Surgery
Costotransverse block is a novel regional anesthesia technique described a few months ago. It's use for breast surgery has been reported by only one case report in the literature.
- Trial name
- NCT04197206
- Testing
- costotransverse block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Cigli Regional Training Hospital
Chronic Pain, Opioid Use
Predicting Chronic Pain Following Breast Surgery
Breast surgery, which includes mastectomy, breast reconstructive surgery, or lumpectomies with sentinel node biopsies, may lead to the development of chronic pain and long-term opioid use.
- Conditions
- Chronic Pain, Opioid Use, Breast Pain, Breast Cancer
- Trial name
- NCT04967352
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of California, San Diego
Malignant Neoplasm of Breast
MIRs 04 : Interpectoral Nerve Block With Ropivacaine Versus Placebo Before Breast Cancer Surgery
Compare the effect of ropivacaine versus placebo pectoral nerve block (Pecs 1 and 2) on acute pain after tumorectomy plus sentinel lymph node dissection on one day surgery.
- Trial name
- MIRs 04 (NCT04327063)
- Testing
- Saline, Ropivacaine
- Where
- 4 sites in France
- Volunteers
- 182 people
- Sponsor
- Institut Curie
Breast Cancer, Post Operative Pain
Analgesic Effect of Serratus Plane Block With Adjuvant Agents in Breast Cancer Surgery
Pain after breast surgery has been described as moderate to severe in intensity and, if inadequately treated, increases postoperative morbidity, hospital cost, and the incidence of persistent postoperative pain.
- Trial name
- NCT07081581
- Testing
- Bupivacain, Bupivacaine and Magnesium sulfate, Bupivacaine and Dexmedetomidine ile Blokaj
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Breast Neoplasms
Upper Limb Function After Breast Cancer Surgery: the Role of Post-operative Physical Therapy Intervention
Surgical treatments can cause late effects influencing activity of daily living, physical activity, and overall health. Late effects include persistent pain reported by 30 - 50% of women that underwent breast operations…
- Trial name
- NCT03389204
- Testing
- PHYSICAL THERAPY
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Assuta Medical Center
Breast Cancer Female, Postoperative Pain
Multimodal Pain Treatment for Breast Cancer Surgery - a Prospective Cohort Study
Breast cancer is one of the most common types of cancer among women worldwide. (1) Breast-conserving surgery or mastectomy is indicated for the majority of patients with this type of cancer.
- Conditions
- Breast Cancer Female, Postoperative Pain, Postoperative Nausea and Vomiting
- Trial name
- NCT04875559
- Testing
- Standardised multimodal pain treatment regimen
- Where
- Denmark
- Volunteers
- 236 people
- Sponsor
- Zealand University Hospital
Anxiety Disorder, Breast Cancer
Hypnosis in Reducing Pain and Other Side Effects in Women Undergoing Surgery for Breast Cancer
RATIONALE: Hypnosis may be effective in reducing pain and other side effects in women undergoing surgery for breast cancer. PURPOSE: This clinical trial is studying how well hypnosis works in reducing pain and other side effects…
- Conditions
- Anxiety Disorder, Breast Cancer, Nausea and Vomiting, Pain
- Trial name
- NCT00748267
- Testing
- questionnaire administration, hypnotherapy, therapeutic conventional surgery
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- City of Hope Medical Center
Breast Cancer, Chronic Pain
Can Chronic Post-surgical Pain be Reduced by Preserving Intercostobrachial Nerve During Axillary Lymph Node Dissection? : A Randomized Controlled Trial
Intercostobrachial nerve (ICBN) is a cutaneous nerve that provides sensation to the lateral chest, upper medial arm and axilla. It arises from the second intercostal nerve and leave intercostal space at the level of midaxillary…
- Conditions
- Breast Cancer, Chronic Pain, Intercostobrachial Nerve Injury
- Trial name
- PAINE (NCT05198622)
- Testing
- Intercostobrachial Nerve Preserving Axillary Lymph Node Dissection, Intercostobrachial Nerve Sacrificing Axillary Lymph Node Dissection
- Where
- Pakistan
- Volunteers
- 182 people
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
Breast Cancer, Pain
Chronic Pain in Women Who Have Undergone Surgery for Stage I, Stage II, or Stage III Breast Cancer
RATIONALE: Learning about chronic pain in women who have undergone surgery for breast cancer may help improve the quality of life for these patients and may help doctors plan the best treatment.
- Conditions
- Breast Cancer, Pain, Perioperative/Postoperative Complications
- Trial name
- NCT00971919
- Testing
- questionnaire administration, assessment of therapy complications, psychosocial assessment and care
- Where
- United Kingdom
- Volunteers
- 284 people
- Sponsor
- Aberdeen Royal Infirmary
Neuropathic Pain, Breast Cancer
Biomarkers of Neuropathic Pain in Women Treated for Breast Cancer
Investigators aim to identify the key phenotypes (biological, psychological, genetic) involved in the transition from acute to chronic neuropathic pain (NP) by comparison of the neuropathic pain phenotypes and genomics of…
- Trial name
- NCT02487524
- Testing
- Cold water test, Autonomic nervous system monitoring, QST
- Where
- Finland
- Volunteers
- 402 people
- Sponsor
- Helsinki University Central Hospital
Opioid Use, Breast Cancer
Opioid Dispensing Device for Post-Operative Pain in Cancer Patients
This research study will evaluate the use of, and participants experience with, a new device called Addinex that safely stores and dispenses opioid medication.
- Trial name
- NCT05585788
- Testing
- Addinex Device (ADX-27)
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Columbia University
Cancer-related Pain, Chronic Post Cancer Surgery Pain
Exploring the Link Between Cancer Genetics and PPSP
Pain is common in cancer, affecting between 40 and 60% of patients depending on tumour type and stage of disease, and represents a major area of unmet need in cancer survivors.
- Conditions
- Cancer-related Pain, Chronic Post Cancer Surgery Pain, Breast Cancer
- Trial name
- NCT04007861
- Volunteers
- 104 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Breast Cancer, Breast Cancer Lymphedema
The Recovery of Reaching Movement in Breast Cancer Survivors: Two Different Rehabilitative Protocols in Comparison
This study emphasizes the importance of rehabilitation in breast cancer survivors after mastectomy, even during the course of radiotherapy and chemotherapy, both for good efficacy in reducing pain and for functional recovery of…
- Conditions
- Breast Cancer, Breast Cancer Lymphedema, Pain, Pain, Postoperative
- Trial name
- NCT04166279
- Testing
- Single rehabilitative treatment, Group rehabilitative treatment
- Where
- Italy
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza