Clinical trials: Breast Cancer-Related Lymphedema
Lymphedema, Breast Cancer
The LYMPH Trial - Microsurgical Versus Conservative Treatment of Chronic Breast Cancer Associated Lymphedema
The aim of this study is to test whether lymphatic surgery provides better QoL (assessed with the Lymph-ICF-UL, (Lymphedema Functioning Disability and health questionnaire for upper limb lymphedema)) 15 months after randomization…
- Trial name
- LYMPH (NCT05890677)
- Testing
- Surgical Intervention, Conservative Complex Physical Decongestion Therapy
- Where
- 36 sites in United States, Austria and 13 more
- Volunteers
- 280 people
- Sponsor
- University Hospital, Basel, Switzerland
Lymphedema, Breast Cancer
Gentle Touch for Post-Mastectomy Lymphedema
This is a single-blind, parallel-group Randomized Controlled Trial (RCT) comparing the efficacy of a specialized manual technique, Gentle Touch (GT), versus a control intervention, both added to the usual rehabilitative care.
- Trial name
- GT-BCRL (NCT07257679)
- Testing
- Gentle Touch (GT) Lymphatic Drainage (ANDOS technique), Passive Mobilization and Active-Assisted Exercises for the Upper Limb
- Where
- 2 sites in Italy
- Volunteers
- 36 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Breast Cancer Lymphedema, Survivorship
Lymphatic Response to Resistance Exercise in Breast Cancer Survivors
The objective of this study is 1) to study the acute and chronic effect of resistance therapeutic physical exercise (RTPE) in the prevention of breast cancer-related lymphedema (BCRL) in breast cancer survivors at risk using…
- Conditions
- Breast Cancer Lymphedema, Survivorship, Lymphedema of Upper Limb
- Trial name
- LinfoGYM (NCT06113627)
- Testing
- Resistance Therapeutic Exercise
- Where
- Spain
- Volunteers
- 170 people
- Sponsor
- University of Malaga
Breast Cancer, Lymphedema
Effectiveness of Accelerated Intervention With Compression Sleeve in Mild and Moderate Breast Cancer-related Lymphedema
The purpose of this study is to determine whether accelerated treatment with custom-made compression sleeve is more effective than standard procedure in the treatment of mild and moderate arm lymphedema secondary to primary…
- Trial name
- NCT01954654
- Testing
- Custom-made compression sleeve and -gauntlet, Educational information, recommendation and instruction
- Where
- Denmark
- Volunteers
- 84 people
- Sponsor
- Mette Brodersen Jerver
Breast Cancer
Assessment of Breast Cancer-Related Arm Lymphedema
Lymphedema is a serious complication of breast cancer treatment. Reported prevalence of lymphedema following treatment for breast cancer varies, ranging from 7-45%.
- Trial name
- NCT03978754
- Testing
- ICG lymphography、CM、VD、Bioelectrical impedance technology、self-report, Bioelectrical impedance technology、CM
- Where
- China
- Volunteers
- 1,600 people
- Sponsor
- Peking University People's Hospital
Breast Cancer Related Lymphedema, Breast Cancer-Related Arm Lymphedema
The Effects of Upper Extremity Lymphedema on Posture, Upper Extremity Functions, and Quality of Life
This study aims to examine the effects of lymphedema extremity on upper extremity function, posture and quality of life in patients who develop upper extremity lymphedema after unilateral breast cancer.
- Trial name
- NCT05776433
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Breast Cancer Lymphedema
Effect of the Axillary Lymphatic /Vein Reflux Ratio on Postoperative Upper Limb Edema and Dysfunction in Breast Cancer
The purpose of this study is to compare the difference in the incidence of upper limb edema and dysfunction between the Preponderant lymphatic reflux group (high ratio of axillary lymphatic reflux to axillary vein reflux) and the…
- Trial name
- PLEDGE-R (NCT05246592)
- Testing
- Branches Sparing, None Branches Sparing
- Where
- 3 sites in China
- Volunteers
- 258 people
- Sponsor
- Xiangyun Zong
Autonomic Nervous System Imbalance, Psychological Distress
Stochastic Modulated Vibrations on Autonomic Nervous System of Breast Cancer Patients During Radiotherapy
The aim of this research is to study the influence of stochastic modulated vibrations on the autonomic nervous system of breast cancer patients during radiation therapy
- Conditions
- Autonomic Nervous System Imbalance, Psychological Distress, Cancer-related Pain, Breast Cancer Lymphedema
- Trial name
- NCT04125953
- Testing
- Andullation
- Where
- Belgium
- Volunteers
- 130 people
- Sponsor
- Universitair Ziekenhuis Brussel
Breast Neoplasms, Lymphedema
Impact of Physical Exercise on Lymphedema Related to Breast Cancer: Assessment Using Thermography
Study Type: Clinical Trial Primary Purpose: To determine whether physical exercise improves or prevents lymphedema in breast cancer patients.
- Conditions
- Breast Neoplasms, Lymphedema, Thermography, Exercise
- Trial name
- NCT06905639
- Testing
- Aerobic and Strength Exercise
- Where
- Spain
- Volunteers
- 9 people
- Sponsor
- Marta Arias Crespo
Lymphedema of Upper Limb, Breast Cancer Related Lymphedema
Effectiveness of Stellate Ganglion Block in Breast Cancer Related Lymphedema
Lymphedema is a condition characterized by generalized or regional accumulation of protein-rich interstitial fluid as a result of impaired lymphatic circulation due to congenital or acquired disorders.
- Trial name
- NCT04165512
- Testing
- bupivacaine and triamcinolone
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Marmara University
Post Mastectomy Lymphedema
Effect of Thera-Band Versus Swiss Ball Exercises on Postural Stability in Post Mastectomy Lymphedema
The purpose of the study is to determine the effect of Thera-band exercises versus Swiss ball exercises on postural stability in unilateral post mastectomy lymphedema.
- Trial name
- NCT07019311
- Testing
- Thera-Band exercises, Swiss ball exercises, Traditional physical therapy program
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Cairo University
Breast Cancer, Lymphedema
Lymphedema Surveillance Study
This study is being done to find out how many women develop lymphedema after an axillary lymph node dissection. The investigators also want to look for reasons why some women get lymphedema and others don't.
- Trial name
- NCT02743858
- Testing
- Bilateral arm measurements, Body mass index (BMI), Quality of Life Questionnaire
- Where
- 7 sites in United States
- Volunteers
- 1,250 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Lymphedema Arm, Breast Cancer Lymphedema
Preoperative Indocyanine Green Lymphography and High-Frequency Ultrasound as Predictors of Lymphaticovenous Anastomosis Outcome in Post-Mastectomy Upper Limb Lymphedema
This study aims to evaluate the predictive value of preoperative indocyanine green (ICG) lymphography and high-frequency ultrasound in determining the outcomes of lymphaticovenous anastomosis (LVA) in patients with…
- Trial name
- NCT07614815
- Testing
- lymphatic-venous anastamosis
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Axillary Web Syndrome, Breast Cancer
Axillary Web Syndrome After Breast Cancer Surgery: Incidence, Risk Factors, and Functional Outcomes
Axillary web syndrome (AWS), sometimes called "cording," is a condition that can develop after breast cancer surgery in which the lymph nodes under the arm are removed or sampled.
- Conditions
- Axillary Web Syndrome, Breast Cancer, Breast Cancer Lymphedema, Postoperative Complications
- Trial name
- NCT07780240
- Testing
- Axillary surgery (sentinel lymph node biopsy or axillary lymph node dissection)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Antalya City Hospital
Breast Cancer-Related Lymphedema
Combined Exercise Effects in Breast Cancer-related Lymphedema
Breast cancer-related lymphedema (BCRL) is a common and debilitating condition that affects quality of life, mobility, and well-being.
- Trial name
- LymFit (NCT07365618)
- Testing
- Exercise, Educational Sessions
- Where
- Portugal
- Volunteers
- 58 people
- Sponsor
- Faculdade de Motricidade Humana
Post Mastectomy Lymphedema
Post-Mastectomy Shoulder Pain And Lymphedema Responses To Ga-As Laser Versus Microcurrent Electrical Stimulation
the aim of this study is to investigate the effect of GA-AS laser versus microcurrent on post-mastectomy shoulder pain and lymphedema.
- Trial name
- PM (NCT05870241)
- Testing
- Ga-As Laser, Microcurrent Electrical Stimulation, traditional therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Lymphedema
Bioelectrical Impedance for Self-monitoring of Lymphedema
Breast cancer treatment-related lymphedema requires life-long self-care is required. No objective measurement mechanism exists that can easily be used to self-monitor arm volume.
- Trial name
- NCT01385488
- Testing
- self-monitor arm volume
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Breast Cancer Lymphedema
Does Immediate Lymphatic Reconstruction Decrease the Risk of Lymphedema After Axillary Lymph Node Dissection
The researchers are doing this study to see if having immediate lymphatic reconstruction after axillary lymph node dissection (ALND) can decrease the development of lymphedema, a side effect of ALND.
- Trial name
- NCT04241341
- Testing
- Axillary Lymph Node Dissection with Immediate Lymphatic Reconstruction, Axillary Lymph Node Dissection without Immediate Lymphatic Reconstruction, quality-of-life questionnaires
- Where
- 7 sites in United States
- Volunteers
- 180 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer
Exploring the Efficacy and Feasibility of the LymphaTech Scanner for Breast Cancer-Related Lymphedema Screening
This research will compare the absolute volumes of the upper extremity using both the LymphaTech Scanner and Perometer in a cohort of patients with a history of invasive or in-situ carcinoma of the breast.
- Trial name
- NCT03861975
- Testing
- Breast Cancer-Related Lymphedema Measurements
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Lymphedema, Breast Cancer
LymphoVenous Anastomosis to Prevent Breast Cancer Related Lymphedema
Lymphedema is defined as a chronic condition, caused by lymphostasis. A major part in the Western world consists of iatrogenic lymphedema caused by surgery to the lymph nodes of the axilla or groin.
- Trial name
- LVARCT (NCT05601037)
- Testing
- Axilla dissection + Lymphovenous anastomosis
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- University Hospital, Ghent