Clinical trials: Breast Lesions
Breast Cancer, Breast Abnormalities
Wearable Ultrasound Patch for Breast Imaging
The goal of this clinical trial is to learn if a wearable ultrasound (US) patch can provide reliable whole-breast imaging and accurately detect breast lesions in patients undergoing breast health evaluation.
- Conditions
- Breast Cancer, Breast Abnormalities, Breast Lesion, Breast Asymmetry
- Trial name
- NCT07186491
- Testing
- Wearable Ultrasound Patch
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Breast Lesions
Visualization Tool for Investigation of Breast Lesions
Magnetic resonance imaging (MRI) is commonly used for the detection of breast lesions in genetically high-risk women due to its high sensitivity.
- Trial name
- NCT00934297
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Sunnybrook Health Sciences Centre
Breast Cancer
A Clinical Investigation to Confirm the Ability of MammoWave in Breast Lesions Detection
This is a multicentric, single arm, prospective, stratified by breast density clinical investigation to confirm the ability of the microwave mammogram 'MammoWave' to detect breast lesions.
- Trial name
- NCT05300464
- Testing
- Clinical investigation medical device class IIa marked CE
- Where
- 4 sites in Italy, Spain
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Umbria Bioengineering Technologies
Malignant Breast Cancer, Benign Breast Lesions
Using Test of SCM for Detection Breast Cancer
In our previous research, we have shown that women that have breast cancer have a population of lymphocytes that recognizes specific antigen and there cytoplasmic matrix goes through physical change a short time after exposure in…
- Trial name
- NCT00407706
- Testing
- blood test
- Where
- Israel
- Volunteers
- 180 people
- Sponsor
- Ziv Hospital
Breast Cancer
Elacestrant and Exemestane for Patients With Pretreated HR+/HER2- Metastatic Breast Cancer and [18F] FES-avid Lesions (COMBINE)
Single agent endocrine therapy (ET), with selective estrogen receptor degraders (SERDs; i.e. fulvestrant or elacestrant), is an option for patients with pre-treated hormone receptor-positive (HR+) breast cancer (BC) with indolent…
- Trial name
- COMBINE-01 (NCT07395336)
- Testing
- elacestrant and exemestane
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- European Institute of Oncology
Breast Cancer
Avidination for RadionuclideTHerapy in Nonpalpable Breast Cancer
This is an interventional, open-label, non comparative phase 2 trial enrolling patients with nonpalpable breast cancer
- Trial name
- ARTHE (NCT06390241)
- Testing
- Avidin-biotin-Dota-90Y
- Where
- Italy
- Volunteers
- 18 people
- Sponsor
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Breast Cancer Prevention
Antler Plate on Preventing Mammary High-risk Lesions From Malignant Development
This study aims to prove whether antler disk extract can be put into clinical practice to prevent breast precancerous lesions from developing into cancer.
- Trial name
- NCT04440683
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Jilin University
Breast Cancer, Breast Lesions
Breast Ultrasound Image Reviewed With Assistance of Deep Learning Algorithms
This study evaluates a second review of ultrasound images of breast lesions using an interactive "deep learning" (or artificial intelligence) program developed by Samsung Medical Imaging, to see if this artificial intelligence…
- Conditions
- Breast Cancer, Breast Lesions, Breast Mass
- Trial name
- NCT03706534
- Testing
- Ultrasound Image review with CADe, Ultrasound Image review with CADx, Ultrasound Image manual review
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Samsung Medison
Breast Cancer
BIOPSY SCANNER LLTECH© Technology for Diagnosis of Breast Cancer
Breast cancer is a frequent pathology and the speed of initial diagnosis makes it possible to improve the course of care and to reduce the anxiety of the patients.
- Trial name
- LLTECHBreast (NCT04292821)
- Where
- France
- Volunteers
- 217 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breast Diseases
REGENERA Implant in Localized Non-malignant Breast Lesions Treated by Excision or Lumpectomy - Long-term Follow-up
In a previous first-in-human (FIH) study we assessed safety and performance of REGENERA in 15 patients treated for breast deformities following excision or lumpectomy.
- Trial name
- NCT05533099
- Testing
- Observational study
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- Tensive SRL
Breast Cancer
Digital Breast Tomosynthesis Guided Tomographic Optical Breast Imaging (TOBI)
Screening for breast cancer improves early detection of aggressive cancers and has been shown to reduce breast cancer related mortality.
- Trial name
- NCT02033486
- Testing
- TOBI + DBT
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Deleterious BRCA1 Gene Mutation, Deleterious BRCA2 Gene Mutation
Diabetes Prevention Program With or Without Hunger Training in Helping to Lower Breast Cancer Risk in Obese Participants
This pilot trial studies how well a diabetes prevention program with or without hunger training works in helping to lower breast cancer risk in obese participants.
- Conditions
- Deleterious BRCA1 Gene Mutation, Deleterious BRCA2 Gene Mutation, Ductal Breast Carcinoma In Situ, Obesity
- Trial name
- NCT03546972
- Testing
- Behavioral, Psychological or Informational Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Breast Neoplasms, DWI
Multiple B-value Diffusion-weighted Imaging(DWI) in Evaluation of Breast Lesions
Breast cancer is the most commonly diagnosed cancer in women and its definite diagnose is still challenge for radiologist. This study is going to evaluate multi-b value diffusion weighted imaging in discrimination of breast…
- Trial name
- NCT02529384
- Testing
- Breast magnetic resonance scanning
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tang-Du Hospital
Breast Cancer
Clinical Effectiveness of CEM in Diagnosis of Additional Findings at Preoperative Breast Magnetic Resonance Imaging
In order to explain the value of adding CESM into the clinical pathway, and also to obtain the relevant clinical data to support future update of clinical guideline, we plan to evaluate the detection rate of CESM for additional…
- Trial name
- COMBO-I (NCT06475066)
- Testing
- contrast-enhanced spectral mammography
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Breast Cancer, Breast Benign
Development Of A Blood Test To Improve The Performance Of Breast Cancer Screening
The purpose of this study is to collect blood and tissue to help develop tests that might be able to detect cancer earlier. The investigator will be collecting these samples and reviewing test results from participants who have…
- Trial name
- NCT03372902
- Testing
- Breast MRI, Breast Mammogram, Blood draw
- Where
- 7 sites in United States
- Volunteers
- 628 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer, Breast Lesions of Uncertain Malignant Potential (B3 Lesions)
BRCA1, RASSF1A and PTEN Methylation in Breast Lesions of Uncertain Malignant Potential
This prospective interventional diagnostic study evaluates the clinical utility of methylation analysis of BRCA1, RASSF1A and PTEN genes in breast lesions of uncertain malignant potential (B3 lesions).
- Trial name
- NCT07416500
- Testing
- MS-MLPA Methylation Analysis
- Where
- Slovenia
- Volunteers
- 301 people
- Sponsor
- Institute of Oncology Ljubljana
Breast Cancer
Histologic Diagnoses of Incidentally Detected Lesions on MRI
Patients who received breast MRI will be evaluated for a variety of indications including : # each indication : 1) known cancer staging for local exent, 2)high risk, 3)high suspicion clinical finding, 4)questionable mammo…
- Trial name
- NCT00579735
- Sponsor
- University of Arkansas
Digital Breast Tomosynthesis
Value of Digital Breast Tomosynthesis in Breast Lesions
The aim of the study is to evaluate the added value of digital breast tomosynthesis (DBT) in the characterization of breast lesions.
- Trial name
- NCT06687902
- Testing
- Digital breast tomosynthesis
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Breast Cancer Patients
Evaluation of the Effectiveness and Safety of Laparoscopic Assisted Mastectomy With Preservation of Nipple and Areola, Immediate One-step Breast Reconstruction With Pectoral Muscle Prosthesis and Patch, and Simultaneous Autologous Fat Transplantation
Evaluation of the effectiveness and safety of laparoscopic assisted breast resection with preservation of nipple and areola, combined with chest muscle anterior prosthesis and patch for immediate one-step breast reconstruction…
- Trial name
- NCT07037537
- Testing
- Endoscopic assisted NSM+breast reconstruction+simultaneous fat transplantation
- Where
- China
- Volunteers
- 26 people
- Sponsor
- Henan Cancer Hospital
Metastatic Breast Cancer
Clinical Utility of FES F18 PET/CT in Metastatic Breast Cancer Patients
This is a phase 4, multi-center, open-label, prospective cohort study to evaluate the clinical utility of Fluoroestradiol F18 (Cerianna) PET/CT to guide therapeutic management in ER-positive, HER2-negative metastatic breast…
- Trial name
- NCT05068726
- Testing
- 18F Fluoroestradiol Radiopharmaceutical with PET/CT
- Where
- 24 sites in United States
- Volunteers
- 51 people
- Sponsor
- GE Healthcare