Clinical trials: Breast MRI
Breast Cancer
MRI in Evaluating Early Response to Chemotherapy in Women With Infiltrating Breast Cancer
RATIONALE: Diagnostic procedures, such as magnetic resonance imaging (MRI), may help in learning how well chemotherapy works to kill breast cancer cells and allow doctors to plan better treatment.
- Trial name
- ISNA-Sein (NCT00462696)
- Testing
- Neoadjuvant chemotherapy
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Institut Bergonié
Breast Cancer, Breast MRI
SURPASS Retrospective Study
This study aimed to determine whether sentinel lymph node biopsy (SLNB) could be a reliable option for evaluating nodal status in patients who had responded well to neoadjuvant systemic therapy (NAST), even if they had initially…
- Conditions
- Breast Cancer, Breast MRI, Neoadjuvant Systemic Therapy, Sentinel Lymph Node
- Trial name
- NCT05779982
- Testing
- Sentinel lymph node biopsy followed by axillary lymph node dissection
- Volunteers
- 500 people
- Sponsor
- Gangnam Severance Hospital
Breast Cancer, Benign Breast Condition
ATUSA Ultrasound Diagnostic Imaging for Breast Lesions Evaluation (AUDIBLE) - iSono Health
AUDIBLE is a multi-site, clinical study conducted in the United States aimed at gathering data on 3D Automated Breast Ultrasound imaging using the iSono Health ATUSA system.
- Conditions
- Breast Cancer, Benign Breast Condition, Breast Fibroadenoma, Breast Neoplasms
- Trial name
- AUDIBLE (NCT07505797)
- Testing
- ATUSA 3D Automated Breast Ultrasound System
- Where
- 2 sites in United States
- Volunteers
- 800 people
- Sponsor
- iSono Health, Inc.
Invasive Breast Cancer
Adding Preoperative Radiotherapy Based on Early Treatment Response in Breast Cancer
RAPID-NeoBC is a prospective, multicentre, response-adapted study with a randomized component for adults with operable, nonmetastatic invasive breast cancer receiving guideline-recommended neoadjuvant systemic therapy.
- Trial name
- RAPID-NeoBC (NCT07892508)
- Testing
- Response-adapted preoperative radiotherapy, Guideline-recommended neoadjuvant systemic therapy, Serial contrast-enhanced breast MRI and breast-specific gamma imaging
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Breast Lesions
Visualization Tool for Investigation of Breast Lesions
Magnetic resonance imaging (MRI) is commonly used for the detection of breast lesions in genetically high-risk women due to its high sensitivity.
- Trial name
- NCT00934297
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Sunnybrook Health Sciences Centre
Breast Cancer
Surveillance MRI Registry for Patients Who Had Breast Cancer With Dense Breast Tissue
To create a registry (database) of participants who come in for breast MRI scans. Researchers want to use this information to study if participants with dense breast tissue (tissue that is more difficult to see on mammogram).
- Trial name
- NCT06127797
- Testing
- Questionnaire/Interview
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer
MIRAI-MRI: Comparing Screening MRI for Patients at High Risk for Breast Cancer Identified by Mirai and Tyrer-Cuzick
Accurate risk assessment is essential for the success of population screening programs and early detection efforts in breast cancer. Mirai is a new deep learning model based on full resolution mammograms.
- Trial name
- NCT05968157
- Testing
- Breast MRI, MIRAI
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- University of Massachusetts, Worcester
Breast Cancer
Comparison of MRI and Molecular Breast Imaging in Breast Diagnostic Evaluation
The purpose of this study is to determine the sensitivity of Molecular Breast Imaging (MBI) relative to MRI of the breast in patients undergoing MRI for a clinical concern, or abnormal diagnostic mammogram and/or ultrasound study.
- Trial name
- MBI (NCT00591864)
- Testing
- Molecular Breast Imaging
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Mayo Clinic
Breast Cancer
Intraoperative Radiotherapy for Early Stage Breast Cancer
Up to 200 patients with biopsy proven early stage breast cancer selecting Wide Local Excision (WLE) will undergo mammography, ultrasound (of affected breast and ipsilateral axilla) and contrast enhanced-magnetic resonance imaging…
- Trial name
- IORT (NCT01189851)
- Testing
- Intraoperative Radiotherapy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Hoag Memorial Hospital Presbyterian
Breast Cancer
MRI for Detecting Cancer in Women Who Are at High Risk of Developing Breast Cancer
RATIONALE: Screening tests may help doctors detect cancer cells early and plan more effective treatment for breast cancer. Diagnostic procedures such as MRI may improve the ability to detect breast cancer.
- Trial name
- NCT00003736
- Testing
- motexafin gadolinium, biopsy, breast imaging study
- Where
- 12 sites in United States, Canada
- Volunteers
- 200 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Breast Cancer
3-Dimensional Form and Soft Tissue Biomechanics of the Breast
The goal of this clinical research study is to characterize the 3-dimensional form and mechanical properties of the breast. Researchers want to do this in order to develop new high technology tools for improving the diagnosis and…
- Trial name
- NCT00502814
- Testing
- 3-D Optical Surface Scan, Mechanical Testing, Cutaneous Ultrasound
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer, Breast Diseases
Advanced Diffusion Tensor MRI for Breast Cancer
The purpose of this research is to evaluate the accuracy of the BIT-Motion (Breast Imaging Tensor-Motion) software with non-contrast MRI scanning to detect breast cancer.
- Trial name
- NCT04774471
- Testing
- Evaluation of BIT-Motion software
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Breast Diseases
The Study of Breast MRI Screening and Proton Magnetic Resonance Spectroscopy
To delineate if the chemical composition (lipid and water) in the presumably normal breast of the high risk women is different from those of the low risk group.
- Trial name
- NCT01749748
- Testing
- proton magnetic resonance spectroscopy
- Where
- Taiwan
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Ductal Breast Carcinoma In Situ
MRI and Gene Expression in Diagnosing Patients With Ductal Breast Cancer In Situ
This clinical trial studies magnetic resonance imaging (MRI) and gene expression in diagnosing patients with abnormal cells in the breast duct that have not spread outside the duct.
- Trial name
- NCT02352883
- Testing
- Magnetic Resonance Imaging, Therapeutic Conventional Surgery, Therapeutic Surgical Procedure
- Where
- 76 sites in United States
- Volunteers
- 368 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
Breast Cancer
Use of Compressed Sensing in Breast MRI
Breast MRI is increasingly important in breast screening imaging. It is currently based on dynamic sequences after contrast injection whose temporal resolution must be less than 90 seconds with dynamic acquisitions at different…
- Trial name
- COMPRIM (NCT02826369)
- Testing
- 3.0 Tesla in Magnetic Resonance Imaging
- Where
- France
- Volunteers
- 13 people
- Sponsor
- Institut de Cancérologie de Lorraine
Breast Cancer
Role of Magnetic Resonance Fingerprinting and Quantitative MR Imaging in Breast Cancer
The purpose of this study is to determine if new methods of MRI imaging can better measure participants' response to chemotherapy treatment.
- Trial name
- NCT03650803
- Testing
- 3D MR Fingerprinting scan
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Case Comprehensive Cancer Center
Breast Carcinoma; Magnetic Resonance Imaging; Diffusion Spectrum Imaging
Quantitative Assessment of Diffusion Spectrum Imaging in Breast Cancer
This project intends to prospectively collect patients with suspected breast malignant tumors by ultrasound or mammography. After routine MRI scanning, all patients underwent diffusion spectrum imaging (DSI) sequence scanning.
- Trial name
- NCT05159323
- Testing
- Diffusion Spectrum Imaging
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Xiang Zhang
Breast Cancer
Partial Breast Irradiation in a Low-risk Population Screened With MRI
This is a pilot study to determine if partial breast irradiation (PBI) limited to the region of the tumor bed following lumpectomy in patients screened with MRI provides historically similar rates of local failure, limited acute…
- Trial name
- NCT01255553
- Testing
- Partial Breast Irradiation
- Where
- United States
- Sponsor
- University of Chicago
Breast Cancer
MR Characterisation/Localisation of Breast Cancer
Objective: To determine the accuracy of multi-functional magnetic resonance (MR) in detecting, localising and characterising satellite lesions in relation to an index breast tumour in order to improve definition of clinical…
- Trial name
- NCT01567137
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Breast Neoplasms, DWI
Multiple B-value Diffusion-weighted Imaging(DWI) in Evaluation of Breast Lesions
Breast cancer is the most commonly diagnosed cancer in women and its definite diagnose is still challenge for radiologist. This study is going to evaluate multi-b value diffusion weighted imaging in discrimination of breast…
- Trial name
- NCT02529384
- Testing
- Breast magnetic resonance scanning
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tang-Du Hospital