Clinical trials: Breast Neoplasms, completed
Lung Cancer, Breast Cancer
Clinical Validation of AI-Assisted Radiotherapy Contouring Software for Thoracic Organs at Risk
The goal of this clinical trial is to evaluate performance and clinical applicability of AI-assisted radiotherapy contouring software (iCurveE) for thoracic organs at risk.
- Conditions
- Lung Cancer, Breast Cancer, Esophageal Cancer
- Trial name
- NCT05787522
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Metastatic Breast Cancer
A Clinical Trial to Compare Efficacy and Tolerability of Faslodex With Arimidex in Patients With Advanced Breast Cancer
The purpose of this study is to compare the efficacy and tolerability of Faslodex (fulvestrant) with Arimidex (anastrozole) in postmenopausal women with hormone receptor positive advanced breast cancer.
- Trial name
- FIRST (NCT00274469)
- Testing
- fulvestrant, anastrozole
- Where
- 41 sites in United States, Brazil and 7 more
- Volunteers
- 205 people
- Sponsor
- AstraZeneca
Breast Cancer
Study of Icrucumab (IMC-18F1) or Ramucirumab Drug Product (DP) in Combination With Capecitabine or Capecitabine on Previously Treated Breast Cancer Patients
An open-label, multicenter, randomized, Phase 2 trial in which participant with unresectable, locally advanced or metastatic breast cancer who have been previously treated with anthracycline and taxane therapy receive ramucirumab…
- Trial name
- NCT01234402
- Testing
- Ramucirumab DP, IMC-18F1, Capecitabine
- Where
- 23 sites in United States, Canada
- Volunteers
- 153 people
- Sponsor
- Eli Lilly and Company
Breast Cancer
A Study to Assess Efficacy and Safety of Pertuzumab Given in Combination With Trastuzumab and Vinorelbine in Participants With Metastatic or Locally Advanced Human Epidermal Growth Factor Receptor (HER) 2-Positive Breast Cancer
This two-cohort, open-label, multicenter, phase 2 study will assess the safety and efficacy of pertuzumab given in combination with trastuzumab (Herceptin) and vinorelbine in first line participants with metastatic or locally…
- Trial name
- VELVET (NCT01565083)
- Testing
- Pertuzumab, Trastuzumab, Vinorelbine
- Where
- 80 sites in United States, Brazil and 5 more
- Volunteers
- 213 people
- Sponsor
- Hoffmann-La Roche
Breast Neoplasms
Contrast Enhanced Mammography in Diagnosing Patients With Suspicious Breast Findings
This pilot trial studies how well contrast enhanced mammography works in diagnosing patients with suspicious breast findings. Diagnostic procedures, such as contrast enhanced mammography, may help to reclassify findings seen on…
- Trial name
- NCT03929783
- Testing
- Contrast Enhanced Digital Mammography
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Thomas Jefferson University
Cancer of Breast, Cardiorespiratory Fitness
Change in Cardiorespiratory Fitness and Breast Cancer Incidence and Mortality
The aim of this observational study is to investigate the association between mid-life changes in cardiorespiratory fitness and the risk of breast cancer incidence and mortality among Swedish women.
- Conditions
- Cancer of Breast, Cardiorespiratory Fitness, Occupational Health
- Trial name
- NCT05729451
- Volunteers
- 53,644 people, healthy volunteers welcome
- Sponsor
- The Swedish School of Sport and Health Sciences
Breast Cancer
Intraoperative Radiotherapy for Early Stage Breast Cancer
Up to 200 patients with biopsy proven early stage breast cancer selecting Wide Local Excision (WLE) will undergo mammography, ultrasound (of affected breast and ipsilateral axilla) and contrast enhanced-magnetic resonance imaging…
- Trial name
- IORT (NCT01189851)
- Testing
- Intraoperative Radiotherapy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Hoag Memorial Hospital Presbyterian
Breast Cancer, HER2-negative Breast Cancer
Evaluation of PSMA in HER2- AR+ Metastatic Breast Cancer
The purpose of this research is to determine the expression of prostate specific membrane antigen (PSMA) in human epidermal growth factor receptor 2 (HER2)-negative, androgen receptor (AR)-positive metastatic breast cancer, and…
- Conditions
- Breast Cancer, HER2-negative Breast Cancer, Metastatic Breast Cancer
- Trial name
- NCT04573231
- Testing
- 18F-DCFPyL
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Wisconsin, Madison
Breast Cancer
Real-time Interactive Digital Healthcare System in Patients With Breast Cancer; Randomized Controlled Trial
This study aims to examine the effect of hospital-home linkage short-term rehabilitation therapy using real-time interactive digital healthcare system (Uincare Homeplus) in post-operative patients with breast cancer.
- Trial name
- NCT04316156
- Testing
- Uincare Homeplus, Brochure
- Where
- 2 sites in South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Cancer
Aminocamptothecin in Treating Patients With Advanced Cancer of the Peritoneal Cavity
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of aminocamptothecin in treating patients with advanced…
- Trial name
- NCT00003548
- Testing
- aminocamptothecin colloidal dispersion
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Breast Cancer
Infrared Imaging (Breast Scan IR) for Early Breast Cancer Detection
This protocol will evaluate a new non-invasive infrared imaging system as an adjunctive tool for breast cancer detection that has been approved by the FDA. The technology and device have been developed by Infrared Sciences Corp.
- Trial name
- NCT00195026
- Testing
- Infrared Breast Scan
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Weill Medical College of Cornell University
Intranasal Dexmedetomidine Breast Cancer Local Anaesthesia
Efficacy and Optimal Dose Selection of Intranasal Dexmedetomidine During Breast Lumpectomy Under Local Anaesthesia
This trial is going to evaluate the safety and effectiveness of intranasal DEX(dexmedetomidine) in breast lumpectomy under local anaesthesia,and to investigate the optimal dose of intranasal DEX in breast lumpectomy.
- Trial name
- NCT02675049
- Testing
- 0.9% saline, dexmedetomidine 1µg.kg-1, dexmedetomidine 1.5µg.kg-1
- Volunteers
- 100 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Metastatic Breast Cancer
A Pilot Study Utilizing Proteomic and Genomic Profiling for Patients With Metastatic Breast Cancer
This study will use proteomic and genomic profiling to analyze tumor tissue to see if treatment selected by this analysis will benefit patients.
- Trial name
- SO2 (NCT01919749)
- Testing
- treated recommended
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Translational Drug Development
Metastatic Breast Cancer, Central Nervous System (CNS) Metastases
Intermittent High-Dose Lapatinib in Tandem With Capecitabine for HER2 Overexpressed/Amplified Metastatic Breast Cancer With Central Nervous System (CNS) Metastases
The purpose of this study is to see if capecitabine can be taken safely with different doses of lapatinib in patients with HER-2 positive breast cancer involving brain (brain metastases) and/or in spinal fluid (leptomeningeal…
- Trial name
- NCT02650752
- Testing
- Lapatinib in Tandem With Capecitabine
- Where
- 9 sites in United States
- Volunteers
- 11 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer
18F-FES PET/CT's Additional Clinical Value in ER+ BC
To figure out whethetr 18F-FES PET/CT could influence the staging and management of newly diagnosed Oestrogen Receptor-positive Breast Cancer Patients.
- Trial name
- NCT04006626
- Where
- China
- Volunteers
- 19 people
- Sponsor
- Fudan University
ER-positive, HER2-negative Breast Cancer
A Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]AZD9833
The Sponsor is developing the test medicine, AZD9833 for the potential treatment of estrogen receptor (ER)-positive breast cancer.
- Trial name
- NCT05364255
- Testing
- [14C]AZD9833 Oral Solution, 75 mg
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Breast Cancer
Ultrasound Paravertebral Block in Breast Surgery.
The purpouse of the study is to determine wether Ultrasound Guided,Ens-assisted paravertebral block with single shot is a safe and reliable anesthetic technique in breast surgery.
- Trial name
- NCT01818817
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Campus Bio-Medico University
Lymphedema of Upper Limb, Breast Cancer
Evaluation of the Treatment Response in Breast Cancer Related Lymphedema
This study aims to evaluate the effects of the treatment for breast cancer lymphedema. After taking a detailed history and giving a physical examination, breast cancer related lymphedema patients(n:30) will be informed and will…
- Conditions
- Lymphedema of Upper Limb, Breast Cancer, Breast Cancer Lymphedema
- Trial name
- NCT04766489
- Testing
- Complete Decongtestive Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ege University
Locally Recurrent, Metastatic Breast Cancer ( HER2 Negative)
A Study of Single-Agent Eribulin Mesylate as First-Line Therapy for Locally Recurrent or Metastatic Human Epidermal Growth Factor Receptor Two (HER2) Negative Breast Cancer
The purpose of this study is to assess the efficacy and safety of single-agent eribulin mesylate for first-line treatment of subjects with locally recurrent or metastatic breast cancer.
- Trial name
- NCT01268150
- Testing
- Eribulin mesylate
- Where
- 17 sites in United States
- Volunteers
- 56 people
- Sponsor
- Eisai Inc.
Breast Neoplasms, Lymphedema
Night-time Compression Systems for Breast Cancer Related Lymphedema
Women who have undergone breast cancer surgery may develop swelling of the arm on the side the breast cancer occurred. If the swelling becomes chronic it is called lymphedema.
- Trial name
- NCT01550250
- Testing
- Night-time compression system garment, Day-time compression sleeve
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University of Alberta
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