Clinical trials: Breast Reduction
Breast Cancer, Chronic Pain
Can Chronic Post-surgical Pain be Reduced by Preserving Intercostobrachial Nerve During Axillary Lymph Node Dissection? : A Randomized Controlled Trial
Intercostobrachial nerve (ICBN) is a cutaneous nerve that provides sensation to the lateral chest, upper medial arm and axilla. It arises from the second intercostal nerve and leave intercostal space at the level of midaxillary…
- Conditions
- Breast Cancer, Chronic Pain, Intercostobrachial Nerve Injury
- Trial name
- PAINE (NCT05198622)
- Testing
- Intercostobrachial Nerve Preserving Axillary Lymph Node Dissection, Intercostobrachial Nerve Sacrificing Axillary Lymph Node Dissection
- Where
- Pakistan
- Volunteers
- 182 people
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
Breast Cancer, Colorectal Cancer
Pain and Fatigue Management in Patients With Breast Cancer, Prostate Cancer, Colon Cancer, or Lung Cancer
RATIONALE: Collecting information over time about patients' and health care providers' understanding of pain and fatigue and providing education about pain and fatigue management may improve quality of life.
- Conditions
- Breast Cancer, Colorectal Cancer, Fatigue, Lung Cancer
- Trial name
- NCT00900835
- Testing
- educational intervention, questionnaire administration, study of socioeconomic and demographic variables
- Where
- United States
- Volunteers
- 470 people
- Sponsor
- City of Hope Medical Center
Breast Cancer, Mammographic Density
Karolinska Interventional Study of Mammograhic Density (Karisma-1)
A feasibility study, randomising to either 10 or 20 mg of tamoxifen. The primary aim is to identify the time to mammographic density change and piloting the procedures.
- Trial name
- Karisma-1 (NCT04079517)
- Testing
- Tamoxifen
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Breast Cancer
Mindfulness-based Stress Reduction in Breast Cancer Recovery
The purpose of this study was two-fold: (i) to assess whether MBSR favorably influences psychological status, quality of life, stress hormones, and immune status in breast cancer survivors; and (ii) to explore possible mechanisms…
- Trial name
- NCT00584142
- Testing
- Mindfulness-Based Stress Reduction
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of South Florida
Breast Cancer, Fatigue
Using Pranayama and Deep Breathing Exercises to Reduce Cancer-Related Fatigue and Insomnia During Radiotherapy
The study aims to evaluate the effectiveness of pranayama and deep breathing exercise in reducing fatigue and insomnia in patients receiving radiotherapy due to breast cancer.
- Conditions
- Breast Cancer, Fatigue, Insomnia
- Trial name
- NCT04441827
- Testing
- breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Breast Cancer
Exemestane in Reducing Breast Density in Postmenopausal Women at Risk for Breast Cancer
RATIONALE: High estrogen levels may be associated with dense breast tissue and an increased risk of developing breast cancer. Exemestane may be effective in preventing the development of breast cancer by decreasing estrogen…
- Trial name
- NCT00066586
- Testing
- exemestane
- Where
- 12 sites in United States, Canada
- Volunteers
- 98 people
- Sponsor
- NCIC Clinical Trials Group
Carcinoma, Intraductal, Noninfiltrating, Recurrence, Local Neoplasm
Trial of Low Dose Tamoxifen in Women With Breast Intraepithelial Neoplasia - Long Term Follow-up
The aim of the study is to evaluate whether tamoxifen at a low dose of 5mg/d reduces in the long term the incidence of invasive breast cancer and ductal carcinoma in situ, DCIS (DIN 1c, 2, 3) of the breast, in woman operated for…
- Conditions
- Carcinoma, Intraductal, Noninfiltrating, Recurrence, Local Neoplasm, Breast Neoplasms, Atypical Hyperplasia
- Trial name
- TAM-01 (NCT01357772)
- Testing
- Tamoxifen
- Where
- 14 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Andrea DeCensi
Mammaplasty, Cicatrix
Juvista (Avotermin) in Breast Reduction Surgery Scars
Severe scarring is a common problem following breast reduction surgery, studies have shown that over 64% of patients develop a hypertrophic scar at three months after the operation.
- Trial name
- NCT00432328
- Testing
- Avotermin
- Where
- 6 sites in United Kingdom
- Volunteers
- 39 people
- Sponsor
- Renovo
Surgical Side Infections After Breast Reduction
Increased Microcirculation for Preventing Postoperative Wound Infections in Patients Undergoing Reduction Mammoplasty
In this prospective study we investigated the impact of an improved postoperative microcirculation and its effect of surgical side infections after breast reduction.
- Trial name
- NCT01538173
- Testing
- 250ml HES 6%, 9% NaCl 500ml
- Where
- Germany
- Volunteers
- 334 people
- Sponsor
- Max Dieterich
Cancer Related Cognitive Decline, Non-metastatic Breast Cancer
RAGE Inhibition to Decrease Cardiotoxicity in Women With Early Breast Cancer
This is a pilot study to evaluate the effects of azeliragon to decrease cardiac toxicity from chemotherapy and the safety of azelirgaon when given with chemotherapy.
- Trial name
- RAGE (NCT05256745)
- Testing
- TTP488, ddAC/ddT, TC
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- Georgetown University
Breast Cancer, Obesity
A Weight-Loss Program in Helping Obese Black Women Lose Weight
RATIONALE: A diet and physical activity program followed by a weight-loss maintenance program may help obese black women lose weight.
- Conditions
- Breast Cancer, Obesity, Weight Changes
- Trial name
- NCT00859989
- Testing
- behavioral dietary intervention, exercise intervention, telephone-based intervention
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Illinois Chicago
Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8
Breast Cancer Survivors Who Experience Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS)
This study evaluates the effectiveness of a cognitive behavioral multicomponent treatment program in improving pain, mood, and functioning while reducing medication non-adherence in breast cancer patients with Aromatase Inhibitor…
- Conditions
- Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8
- Trial name
- NCT06106282
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Mayo Clinic
Cancer, Breast, Cancer Colorectal
Interventions to Decrease Financial Toxicity
Financial distress affects 30-70% of cancer patients and describes the burden that patients experience due to the costs of care (CoC).
- Conditions
- Cancer, Breast, Cancer Colorectal, Cancer, Ovarian, Cervical Cancer
- Trial name
- P-COC (NCT05939440)
- Testing
- Proactive Cost of Care (P-COC) intervention, Usual Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Cancer Survivor, Stage I Breast Cancer AJCC v7
Ginseng in Decreasing Cancer-Related Fatigue After Treatment in Cancer Survivors
This randomized pilot trial studies how well North American ginseng extract AFX-2 (ginseng) works in decreasing cancer-related fatigue after treatment in cancer survivors.
- Conditions
- Cancer Survivor, Stage I Breast Cancer AJCC v7, Stage I Colon Cancer AJCC v6 and v7, Stage IA Breast Cancer AJCC v7
- Trial name
- NCT03407716
- Testing
- American Ginseng, Laboratory Biomarker Analysis, Questionnaire Administration
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic
Heredo Familial Tumors, Psycho Oncological Support
Patient Experiences After Risk-Reducing Mastectomy Among Women Carrying BRCA1/2 Pathogenic Variants Without a Diagnosis of Breast Cancer
This is a descriptive, exploratory cross-sectional, single-center national study. The study asks a sample of women carrying pathogenic variants associated with hereditary breast and ovarian cancer who have undergone risk-reducing…
- Trial name
- NCT07821593
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Breast Reduction, Postoperative Pain
Parasternal Block Added to Serratus Anterior Plane Block in Breast Reduction Surgery
This study aims to evaluate the effect of adding a Superficial Parasternal Intercostal Plane Block (PIPB) to the Serratus Anterior Plane Block (SAPB) on postoperative pain control in patients undergoing breast reduction surgery…
- Conditions
- Breast Reduction, Postoperative Pain, Opioid Consumption
- Trial name
- NCT07432256
- Testing
- Serratus Anterior Plane Block (SAPB), Serratus Anterior Plane Block (SAPB) and parasternal intercostal plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Zonguldak Bulent Ecevit University
Breast Cancer
Couples-Based Mindfulness for Young Breast Cancer Survivors
This study aims to improve relationship, psychological, and physical adjustment among young breast cancer survivors (YBCS; diagnosed at age 45 or younger) and their committed/life partners.
- Trial name
- C-MBSR (NCT02840344)
- Testing
- Couples MBSR, Individual MBSR
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University of Missouri-Columbia
Locally Advanced or Metastatic Breast Cancer
The Efficacy of Compression/Ice Gloves/Socks in Patients With UTD1-induced Neuropathy.
This study is a prospective, multicenter, phase Ⅲ trial to evaluate of the compression/ice gloves/socks efficacy in UTD1-induced peripheral sensory and motor neuropathy. 324 patients will be included.
- Trial name
- NCT07638774
- Testing
- compression glove/sock, ice glove/sock
- Where
- China
- Volunteers
- 324 people
- Sponsor
- Fudan University
Nipple Sparing Mastectomy
Robotic-Assisted da Vinci System Prophylactic Nipple-Sparing Mastectomy
This study evaluates the safety and effectiveness of the da Vinci Surgical Systems in prophylactic Nipple Sparing Mastectomy procedures.
- Trial name
- NCT03892980
- Testing
- Nipple-Sparing Mastectomy
- Where
- 6 sites in United States
- Volunteers
- 145 people
- Sponsor
- Intuitive Surgical
Post Operative Pain, Opioid-Related Disorders
Erector Spinae Plane Block Versus Serratus Anterior Plane Block
the aim of the study compare the analgesic effect of erector spinae block and serratus anterior block in breast surgery
- Trial name
- NCT06862752
- Testing
- erector spine plane (ESP) block, Serratus Anterior Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital