Clinical trials: Breast Reduction
Breast Cancer, Mastectomy; Lymphedema
Examining the Cosmetic Results, Quality of Life and Patient Satisfaction Achieved With Skin Reducing Nipple Sparing Mastectomy and Implant Based Breast Reconstruction, and Comparing it to Classic Skin- Sparing Mastectomy and Implant- Based Breast Reconstructive Surgeries
This is a response-adaptive (RAR) prospective randomized study with a long-term follow-up and the aim of this clinical study is to measure with qualitative and quantitative indicators the changes in cosmetic results, quality of…
- Conditions
- Breast Cancer, Mastectomy; Lymphedema, Quality of Life, Patient Satisfaction
- Trial name
- NCT04345081
- Testing
- Skin Reducing Nipple Sparing Mastectomy and Implant Based Breast Reconstruction, Skin- Sparing Mastectomy and Implant- Based Breast Reconstructive Surgery
- Where
- Hungary
- Volunteers
- 110 people
- Sponsor
- National Institute of Oncology, Hungary
Malignant Neoplasm of Breast, Hodgkin Disease
Defining PET / CT Protocols With Optimized F18-FDG (Fluorodeoxyglucose) Dose, Focusing on Reduced Radiation Dose and Improved Image Quality
Identify the best combination of predictive variables that influence ionizing radiation dose and improved image quality through analysis and quantification of PET-CT images in simulators and patients.
- Conditions
- Malignant Neoplasm of Breast, Hodgkin Disease, Non-Hodgkin Lymphoma, Follicular (Nodular), Malignant Neoplasm of Bronchus and Lung
- Trial name
- pet-ct (NCT02378337)
- Testing
- Image quantify
- Where
- Brazil
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- Hospital Sao Rafael
Seroma, Aspiration
Seroma Reduction After Mastectomy
Rationale: Seroma formation and its sequelae form the mainstay of complications in breast cancer surgery. Seroma has an incidence of 3% to 85%.
- Conditions
- Seroma, Aspiration, Breast Cancer
- Trial name
- SAM (NCT03305757)
- Testing
- Artiss, vicryl sutures, Conventional
- Where
- Netherlands
- Volunteers
- 339 people
- Sponsor
- Zuyderland Medisch Centrum
Breast Neoplasms
The Plan and Stand Study: Reducing Sitting Time in Breast Cancer Survivors
Excessive sitting time (sedentary time) has been associated with risk of insulin resistance and other factors which may be relevant to breast cancer prognosis.
- Trial name
- NCT02510430
- Testing
- Re-Patterning Sitting Time Group, Reducing Sitting Time Group, Usual Care
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Wisconsin, Madison
Analgesia
Bilateral Rhomboid Intercostal Block for Perioperative Analgesia in Patients Undergoing Bilateral Reduction Mammoplasty
Bilateral reduction mammoplasty is one of the most commonly performed breast surgery. The Postoperative pain following it should be minimized.
- Trial name
- NCT06225895
- Testing
- general anesthesia, Erector spinae plane block, a rhomboid intercostal nerve block
- Where
- 2 sites in Egypt
- Volunteers
- 72 people
- Sponsor
- Zagazig University
Drain Output After Breast Reduction Surgery, Breast Reductions
Effect of Intravenous and Topical Tranexamic Acid on Drain Output in Breast Reduction Surgery
This study aims to evaluate whether tranexamic acid (TXA), a medication that helps reduce bleeding, can decrease fluid drainage after breast reduction surgery.
- Trial name
- NCT07131592
- Testing
- IV TXA, Topical TXA, Topical saline
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Massachusetts General Hospital
Risk Reduction Behavior
Self-Affirmation: Construct Validity
Background: People respond differently when asked about their values. They also respond differently when they learn about how their actions affect their lives and health. Researchers want to learn more about these differences.
- Trial name
- NCT02317367
- Where
- United States
- Volunteers
- 3,112 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Sensitivity of Nipple-areolar Complex
Nipple-Areola Complex Sensitivity After the Section of Periareolar Dermis in Breast Reduction
The purpose of this study is to evaluate the feasibility and sensitivity of nipple-areolar complex (NAC) prospectively due to the section of the dermis after decortication (Schwartzmann's maneuver), in 50 patients undergoing…
- Trial name
- NCT01789450
- Testing
- Section of Periareolar Dermis in Breast Reduction.
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Breast Cancer
A Study to Learn About the Dangers Linked to Myelosuppression (Decreased Bone Marrow Function) in Breast Cancer Patients Treated With the Study Medicine Palbociclib (Pal Bow Sai Klib)
The purpose of this study is to explore risk factors for grade 4 neutropenia in users of the study medicine Palbociclib for the potential treatment of Palbociclib.
- Trial name
- NCT05709158
- Where
- United States
- Volunteers
- 4,184 people
- Sponsor
- Pfizer
Hyperplasia
Harmonic Scalpel Vs. Electrocautery in Breast Reduction Surgery
Purpose: The aims of this randomized clinical trial are to assess and compare 3 different outcomes in women undergoing breast reduction surgery using two different surgical devices: the Harmonic Scalpel and electrocautery.
- Trial name
- NCT00819260
- Testing
- Harmonic Scalpel, Electrocautery
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Patient Relations, Nurse, Patient Satisfaction
Aromatherapy Methods in Reducing Anxiety Before Breast Biopsy
A breast biopsy is a cause for anxiety for most women when faced with a diagnosis of breast cancer. Physiological and psychological effects of breast biopsy may continue in the pre-biopsy and post-biopsy period.
- Conditions
- Patient Relations, Nurse, Patient Satisfaction, Anxiety State, Breast Cancer
- Trial name
- NCT05276505
- Testing
- Lavender Aromatherapy Tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Perioperative Fluid Management
Comparison of Hemodynamic Results of Two Different Fluid Managements
In the reduction mammoplasty operations performed in the Plastic and Reconstructive surgery operating room in our clinic, the female patient group, who does not have co-morbidities and does not exceed middle age, is followed by…
- Trial name
- NCT05733403
- Testing
- isotonic solution, Noradrenaline
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Breast Cancer
Complementary Therapies for the Reduction of Side Effects During Chemotherapy for Breast Cancer
The purpose of this study is to determine wether a complementary therapy consisting of a combined medication of selenium, milk thistle, goldenrod and bromelain and a consultation concerning nutrition and physical activity can…
- Trial name
- NCT00160901
- Testing
- two complex naturopathic add-on therapies, leaflet 5-a-day
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Heidelberg University
Breast Cancer
Penguin Cold Caps in the Prevention of Hair Loss in Breast Cancer Patients
The goal of this study is to estimate the efficacy of Penguin cold caps in preventing or reducing hair loss in patients receiving (neo)adjuvant chemotherapy (one of four common regimens) for early stage breast cancer.
- Trial name
- NCT03289364
- Testing
- Penguin Cold Caps
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Providence Health & Services
Breast Cancer, Lymphedema
Flexitouch Lymphedema System in Treating Stage II Lymphedema in Patients With Breast Cancer
RATIONALE: The Flexitouch lymphedema system may lessen lymphedema caused by treatment for breast cancer. It is not yet known whether the Flexitouch lymphedema system is more effective than complex decongestive therapy in treating…
- Trial name
- NCT01019512
- Testing
- questionnaire administration, lymphedema management
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Peripheral Neuropathy in Breast Cancer Patient
Nutraceuticals Versus Usual Care in the Prevention or Reduction of CIPN in Patients Treated With Docetaxel as Neoadjuvant/Adjuvant Breast Cancer Therapy
The trial will utilize Nutraceuticals (Vitamin D 2000IU oral once daily, Vitamin B6 100 mg oral once daily, Vitamin B12 100 mcg oral once daily, Omega-3 Fatty Acids 900 mg oral three times a day) in patients treated with…
- Trial name
- CIPN (NCT02795572)
- Testing
- Vitamin D, Vitamin B6, Vitamin B12
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- AHS Cancer Control Alberta
Breast Cancer, Uterine Cancer
Musicotherapy in the Reduction of Fatigue in Women With Breast or Gynecological Cancer Under Radiotherapy
OBJETIVE: To study the influence of musicotherapy in reduction of fatigue related to cancer in patients with breast's or gynecology's cancer, during the radiotherapy treatment.
- Conditions
- Breast Cancer, Uterine Cancer, Ovarian Cancer
- Trial name
- NCT01570218
- Testing
- Music therapy
- Where
- 2 sites in Brazil
- Volunteers
- 164 people
- Sponsor
- Universidade Federal de Goias
Breast Cancer
Impact of Topical Tranexamic Acid in Breast Reconstruction
Improvement in bleeding and bruising has been described by using both intravenous and topical off-label applications of Tranexamic Acid (TXA) in many surgical fields.
- Trial name
- NCT05807074
- Testing
- Tranexamic Acid, Saline
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of California, San Francisco
Surgical Scars
Evaluation of the Scar Healing Effects of ChitoCare Medical Scar Healing Gel in Women Undergoing Breast Reduction or Mastopexy Surgery (CHITOSCAR)
Patients undergoing breast reduction or mastopexy surgery will be screened and recruited for participation in the study. Eligible patients will act as their own control with one breast receiving the active intervention…
- Trial name
- CHITOSCAR (NCT06992960)
- Testing
- ChitoCare® medical Scar Healing Gel (Örsáragel), Amoena CuraScar Mammilla Circles Silicone Scar Patch and Amoena CuraScar Anchors Silicone Scar Patch
- Where
- Iceland
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Primex ehf
Pain of Anesthesia at Breast Biopsy
Reducing Pain of Lidocaine Injection
The purpose of this study is to determine the benefit, if any, of buffering lidocaine (adding sodium bicarbonate) when used for local anesthesia prior to percutaneous breast needle core biopsies.
- Trial name
- NCT02288364
- Testing
- 1% Lidocaine, 1% Lidocaine plus sodium bicarbonate
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Duke University