Clinical trials: Breast Reductions
Malignant Neoplasm of Breast
An Early Stress-Reduction Intervention in Patients With Newly Diagnosed Breast Cancer
The goal of this research study is to learn if starting a stress-reduction program before treatment can affect your stress, mood, and physical symptoms during and after treatment for cancer. This is an investigational study.
- Trial name
- NCT03429907
- Testing
- Mind-Body Exercises, Questionnaires
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- M.D. Anderson Cancer Center
Seroma Complicating A Procedure, Hematoma Postoperative
SEroma Reduction pOst MAstectomy "SEROMA Study"
This is a pilot study to evaluate the feasibility of conducting a larger trial to determine if the use of intraoperative topical tranexamic acid (TXA) decreases the rate of post-operative hematomas and seromas in breast cancer…
- Conditions
- Seroma Complicating A Procedure, Hematoma Postoperative, Breast Cancer
- Trial name
- SEROMA (NCT03738527)
- Testing
- Tranexamic Acid 100mg/mL, 20mL topical, Normal Saline Flush, 0.9%, 20mL topical
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Hamilton Health Sciences Corporation
Breast Benign Tumor, Breast Malignant Tumor
Evaluating the Performance of AI in Evaluating Breast MRI Performed With Dose Reduction
The purpose of this study is to evaluate the ability of AI to correctly aid in characterization of benign and malignant lesions even when a low dose of gadolinium is administered.
- Trial name
- NCT04340180
- Testing
- Standard of Care (SOC) gadolinium Breast MRI, reduced 1/4 dose gadolinium Breast MRI with Artificial Intelligence (AI) to aid in evaluation.
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Macromastia
Study of Prineo (Dermabond Protape) Versus Sutures in Breast Procedures
This is a prospective, controlled, randomized, multi-center clinical study of up to 80 patients with full thickness surgical incisions associated with bi-lateral breast procedures.
- Trial name
- NCT00558246
- Testing
- Dermabond Protape (Prineo), Suture
- Where
- 5 sites in Belgium, Germany and 2 more
- Volunteers
- 79 people
- Sponsor
- Ethicon, Inc.
Breast Carcinoma
Myofascial Release or Trigger Point Injections for the Reduction of Post-Mastectomy Pain Syndrome
This clinical trial studies the effect of myofascial release in decreasing post-mastectomy pain compared to standard of care trigger point injections in patients with post-mastectomy pain syndrome.
- Trial name
- NCT05041751
- Testing
- Acupuncture Point Injection, Massage Therapy, Quality-of-Life Assessment
- Sponsor
- M.D. Anderson Cancer Center
Breast Reduction
Reduction of Breast Hypertrophy by Means of Coelioscopique Surgery
The objective of this interventional study is based on the hypothesis that coelioscopique surgery could be used to reduce breast hypertrophy.
- Trial name
- R-HTM-R (NCT05822115)
- Testing
- Reduction of breast hypertrophy by means of laparoscopic
- Where
- France
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Groupe Hospitalier Nord-Essonne
Patients With Breast Cancer Requiring Mastectomy and Suitable for Reconstruction
Impact of ADM in Reduction of Surgical Complexity of Breast Reconstructions With Implants (Nava)
The objective of this study is to demonstrate that acellular dermal matrix, Strattice™ Reconstructive Tissue Matrix, can reduce the surgical complexity and post-operative pain of breast reconstructions with implants by avoiding…
- Trial name
- NCT01853436
- Testing
- Strattice™ Reconstructive Tissue Matrix
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- LifeCell
Breast Cancers, Gynecologic Cancer
The Effect Of Meditation On Quality Of Life In Women With Breast Cancer And Other Gynecological Cancers
Women with breast cancer and other gynecologic cancers often suffer significant distress and disability from their disease. A practice of meditation-based stress reduction and cognitive-affective-behavioral learning may help…
- Trial name
- NCT00248911
- Testing
- Mindfulness based meditation program
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Weill Medical College of Cornell University
Pain Management
Serratus Plane Block For Breast Reduction Surgery
Serratus plane block was first described in 2013 by Blanco and designed to primarily block the thoracic intercostal nerves. And this block provides sufficient analgesia lateral anterior and posterior part of thoracic…
- Trial name
- SPB (NCT02930733)
- Testing
- Bupivacaine, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ataturk University
Breast Reduction, Reduction Mammoplasty
Risk of Hematoma After Ketorolac Use in Reduction Mammoplasty.
The investigators hope to answer the question, "does ketorolac increase the risk of hematoma after reduction mammoplasty?" using a case-control study.
- Conditions
- Breast Reduction, Reduction Mammoplasty, Hematoma, Hemorrhage
- Trial name
- NCT03280043
- Testing
- Hematoma
- Where
- 2 sites in Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- McMaster University
Breast Cancer
A Novel Optical Spectral Imaging System for Imaging Breast Tumor Margins
The goal of this research is to further develop novel optical assay systems for intra operative assessment of tumor margins in partial mastectomy or mastectomy specimens.
- Trial name
- NCT01372631
- Testing
- miniature spectral imaging system, Bench-top optical spectrometer, High resolution microendoscope
- Where
- 2 sites in United States
- Volunteers
- 218 people
- Sponsor
- Duke University
Wounds and Injuries, Cancer Pain
Benefits of Morphine Gel for Pain Reduction in Patients With Cancer Wounds
The goal of this clinical trial is to compare in compare pain reduction in patients with malignant wounds using morphine gel or lidocaine gel.
- Conditions
- Wounds and Injuries, Cancer Pain, Cancer, Breast, Cancer Head Neck
- Trial name
- MorphineGEL (NCT05800834)
- Testing
- Morphine Sulfate, Lidocaine Hcl 2% Jelly
- Where
- Brazil
- Volunteers
- 106 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Hematoma Postoperative, Venous Thromboembolism
Use of Tranexamic Acid in Reduction Mammoplasty
Breast reduction mammoplasty (BRM) is among the most commonly performed procedures in plastic surgery. However, postoperative hematoma is one of the most common complications following BRM.
- Trial name
- TREX-ARM (NCT04947514)
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Breast Atypical Hyperplasia, Breast Carcinoma
Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction
This phase II trial evaluates tamoxifen, with or without omega-3 fatty acids, for reducing risk of breast cancer among postmenopausal and overweight or obese women who are at increased risk of developing breast cancer.
- Conditions
- Breast Atypical Hyperplasia, Breast Carcinoma, Breast Ductal Carcinoma In Situ, Breast Lobular Carcinoma In Situ
- Trial name
- NCT06195306
- Testing
- Biospecimen Collection, Mammography, Omega-3-Acid Ethyl Esters
- Where
- 3 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Evaluation of Short Scar Periareolar Inferior Pedicle Reduction Mammoplasty in Oncoplastic Breast Surgery
in Our Study we Compare Results of Two Oncoplastic Breast Surgery (Short Scar Reduction Mammoplasty and Wise Pattern Reduction Mammoplasty) as Surgical Treatment of Breast Cancer
in our study we compare results of two oncoplastic breast surgery (short scar reduction mammoplasty and wise pattern reduction mammoplasty) as surgical treatment of breast cancer
- Trial name
- NCT06901180
- Testing
- short scar periareolar inferior pedicle reduction mammoplasty
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Breast Cancer
Couples-Based Mindfulness for Young Breast Cancer Survivors
This study aims to improve relationship, psychological, and physical adjustment among young breast cancer survivors (YBCS; diagnosed at age 45 or younger) and their committed/life partners.
- Trial name
- C-MBSR (NCT02840344)
- Testing
- Couples MBSR, Individual MBSR
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University of Missouri-Columbia
Carcinoma, Intraductal, Noninfiltrating, Recurrence, Local Neoplasm
Trial of Low Dose Tamoxifen in Women With Breast Intraepithelial Neoplasia - Long Term Follow-up
The aim of the study is to evaluate whether tamoxifen at a low dose of 5mg/d reduces in the long term the incidence of invasive breast cancer and ductal carcinoma in situ, DCIS (DIN 1c, 2, 3) of the breast, in woman operated for…
- Conditions
- Carcinoma, Intraductal, Noninfiltrating, Recurrence, Local Neoplasm, Breast Neoplasms, Atypical Hyperplasia
- Trial name
- TAM-01 (NCT01357772)
- Testing
- Tamoxifen
- Where
- 14 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Andrea DeCensi
Abdominoplasty, Breast Reduction
The Impact of Nutritional Optimization to Enhance Postoperative Outcomes Using the R-Support Supplements
The aim of this pilot study is to evaluate the potential benefits of nutrient supplementation on post-operative recovery for patients undergoing certain types of surgery, compared to those who do not receive such supplementation.
- Conditions
- Abdominoplasty, Breast Reduction, Autologous Breast Reconstruction, Body Contouring Surgery
- Trial name
- R-Support (NCT06601868)
- Testing
- R-Support Prepare & After nutritional supplement
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Breast Cancer
Nutrition Intervention in Treating Women With Breast Cancer
RATIONALE: Dietary fat may be involved in the growth of cancer cells. Restricting dietary fat may help fight cancer. PURPOSE: Randomized clinical trial to study the effectiveness of a low fat diet in treating postmenopausal women…
- Trial name
- NCT00002564
- Testing
- educational intervention, therapeutic dietary intervention
- Where
- 37 sites in United States
- Volunteers
- 2,500 people
- Sponsor
- Institute for Cancer Prevention (IFCP)
Recurrent Ptosis of the Breast
Seri Surgical Scaffold Support of the Lower Pole of the Breast
Will the use of an FDA approved highly purified silk scaffold; Seri Surgical Scaffold help shape and hold the breast up on the chest preventing re-stretching and bottoming out of the breast in breast reduction or…
- Trial name
- SeriSupport (NCT02016612)
- Testing
- Seri Surgical Scaffold
- Where
- 2 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Bengtson Center