Clinical trials: Breast Tumor Tissue
Breast Cancer
Efficacy and Safety of Sintilimab and Apatinib Combined Chemotherapy in Breast Cancer
1. The efficacy and safety of immunotherapy and antiangiotherapy in combination with chemotherapy in neoadjuvant therapy for triple-negative breast cancer (TNBC) were determined by the addition of sintilimab and apatinib to…
- Trial name
- NCT04722718
- Testing
- Sintilimab+Apatinib+Albumin-Bound Paclitaxel(Nab-Paclitaxel)+Carboplatin
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Jiuda Zhao
Breast Cancer, Inflammatory Breast Cancer
Refining Local-Regional Therapy for IBC
This Feasibility study is trying to determine: If Lymphoscintigraphy (imaging of the lymphatic drainage patterns) is effective in demonstrating the drainage to the sentinel lymph nodes in patients with inflammatory breast cancer.
- Conditions
- Breast Cancer, Inflammatory Breast Cancer, Sentinel Lymph Node
- Trial name
- NCT04636710
- Testing
- Lymphoscintigraphy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer
The Effect of Oral Administration of Hesperidin and Diosmin in Reducing Paclitaxel-induced Peripheral Neuropathy in Breast Cancer Patients
The aim of this study is evaluation of the potential neuroprotective effect of oral hesperidin and diosmin in reducing paclitaxel- induced peripheral neuropathy in the treatment of breast cancer patients.
- Trial name
- NCT06811220
- Testing
- Hespiridin and Diosmin
- Volunteers
- 140 people
- Sponsor
- Alexandria University
Advanced or Metastatic Breast Cancer
Pelareorep and Paclitaxel Injection in Chinese Patients With Advanced or Metastatic Breast Cancer
This ia a multicenter, Single-Arm, Open-Label Phase I Clinical Study Evaluating the Safety and Tolerability of Pelareorep Combined with Paclitaxel Injection and the Intracorporal Process of Pelareorep in Chinese Patients with…
- Trial name
- NCT05519059
- Testing
- Pelareorep
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Adlai Nortye Biopharma Co., Ltd.
Breast Cancer, HER2 Gene Mutation
Pyrotinib in Metastatic HER2 Non-amplified But HER2 Mutant Breast Cancer
A Phase II Study of Pyrotinib in Metastatic HER2 Non-amplified But HER2 Mutant Breast Cancer
- Trial name
- NCT03412383
- Testing
- Pyrotinib
- Where
- China
- Volunteers
- 14 people
- Sponsor
- Peking Union Medical College
Breast Cancer, Melanoma
Immunological Variables Associated to ICI Toxicity in Cancer Patients
This is a monocentric, prospective, pilot study that will enrol 435 subjects with solid tumours that are treated with immune checkpoint inhibitor(s) (ICI) alone or in combination with chemotherapy or targeted therapy.
- Conditions
- Breast Cancer, Melanoma, Non Small Cell Lung Cancer, Non-melanoma Skin Cancer
- Trial name
- NCT05429866
- Testing
- Checkpoint Blockade, Immune
- Where
- Belgium
- Volunteers
- 441 people
- Sponsor
- Jules Bordet Institute
Breast Cancer
Adjuvant CDK4/6 Inhibitor Use in HR+/HER2- Breast Cancer
To evaluate the efficacy and safety of adjuvant CDK4/6 inhibitors in patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative breast cancer.
- Trial name
- NCT07180056
- Testing
- CDK4/6 inhibitor
- Where
- China
- Volunteers
- 229 people
- Sponsor
- Wenjin Yin
Breast Neoplasms
Biomarkers Investigation of Neoadjuvant Chemotherapy for Breast Cancer
The BINC-B trial is a diagnostic and interventional study in which various function imaging methods as Magnetic Resonance Imaging (PWI, DWI and DCE-MRI) and will be compared with common imaging methods (mammography and/or…
- Trial name
- BINC-B (NCT03242551)
- Testing
- Chemotherapy
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- Shenzhen People's Hospital
Breast Cancer, Early Breast Cancer
A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy
This is a Phase III open-label study to assess if camizestrant improves outcomes compared to standard endocrine therapy in patients with ER+/HER2 - early breast cancer with intermediate or high risk for disease recurrence who…
- Trial name
- CAMBRIA-1 (NCT05774951)
- Testing
- Camizestrant, Tamoxifen, Anastrozole
- Where
- 709 sites in United States, Argentina and 37 more
- Volunteers
- 4,300 people
- Sponsor
- AstraZeneca
Breast Cancer Metastatic, Breast Cancer Survival
21-gene in Elder Breast Cancer Patients With Lymph Node Metastasis
This study is a single-center, bidirectional cohort study. It aims to include 35 elderly (≥65 years old) Luminal A type breast cancer patients with axillary lymph node metastasis after surgery as the research subjects.
- Trial name
- QiluElderHope (NCT06891651)
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Qilu Hospital of Shandong University
HER2-positive, Adenocarcinoma
CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors
Phase 1, first-in-human, open label study of CAR macrophages in HER2 overexpressing solid tumors.
- Conditions
- HER2-positive, Adenocarcinoma, Bile Duct Cancer, Biliary Tract Cancer
- Trial name
- NCT04660929
- Testing
- CT-0508, Pembrolizumab
- Where
- 7 sites in United States
- Volunteers
- 48 people
- Sponsor
- Carisma Therapeutics Inc
Breast Cancer
Combination Chemotherapy With or Without Capecitabine and/or Trastuzumab Before Surgery in Treating Women With Stage I, Stage II, or Stage III Breast Cancer
RATIONALE: Drugs used in chemotherapy, such as epirubicin, cyclophosphamide, docetaxel, and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00288002
- Testing
- trastuzumab, capecitabine, cyclophosphamide
- Where
- Germany
- Volunteers
- 1,500 people
- Sponsor
- GBG Forschungs GmbH
Breast Neoplasms, Carcinoma, Non-Small-Cell Lung
A Study of DM001 in Patients With Advanced Solid Tumors
The goal of this clinical trial is to find out about the safety, efficacy, and tolerability of DM001 for patients with the advanced solid tumors.
- Conditions
- Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Solid Carcinoma
- Trial name
- NCT06475937
- Testing
- DM001
- Where
- 5 sites in United States, Australia
- Volunteers
- 128 people
- Sponsor
- Xadcera Biopharmaceutical (Suzhou) Co., Ltd.
Breast Carcinoma, Breast Cancer
Exploring Cultural Acceptability of Community Breast Cancer Risk Assessment Among Hispanic Women in Maricopa County
This study explores the cultural acceptability of community breast cancer risk assessment among Hispanic women in Maricopa county.
- Conditions
- Breast Carcinoma, Breast Cancer, Breast Cancer Female
- Trial name
- NCT06112795
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Breast Carcinoma
Patient Navigation and Tailored Treatment Planning in Latina Patients With Breast Cancer
This research trial studies how well patient navigation and tailored treatment planning work in Latina patients with breast cancer.
- Trial name
- NCT02483377
- Testing
- Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Southern California
Breast Neoplasms, Over Cancer
The Effect of Foot Massage With Roles on Cancer Patients
It was aimed to examine the roles in the management of treatment-related peripheral neuropathy in cancer patients receiving taxane-based chemotherapy and the effect of foot massage on neuropathy and quality of life.
- Conditions
- Breast Neoplasms, Over Cancer, Foot Massage
- Trial name
- NCT06376357
- Testing
- Foot Massage with roller
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Selcuk University
Modified Radical Mastectomy, Breast Cancer
Comparison Between Erector Spinae Plane Block Versus Serratus Anterior Plane Block Regarding Analgesia Post Modified Radical Mastectomy
The goal of this clinical trial is to compare Ultrasound Guided Erector Spinae and Ultrasound Guided Serratus Anterior Plane Block post Modified Radical Mastectomy in adult females.
- Trial name
- FMASUMD66/2025 (NCT06947330)
- Testing
- Unilateral Erector Spinae group, Unilateral Serratus Anterior group
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Kholoud Usama
Breast Cancer
Preoperative Oral Dexamethasone to Improve Recovery After Surgery
Randomized controlled trial of pre-operative oral dexamethasone vs placebo for the improvement of quality of recovery from surgery. The study population is limited to breast surgery patients.
- Trial name
- NCT02234466
- Testing
- Oral dexamethasone, Ondansetron, Gelatin capsule
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of Manitoba
Breast Cancer
Addtional Effect of Hyperbaric Oxygen to Programmed Physical Activity on Musckoloskeletal Pain in Breast Cancer Elderly
patienst who survived from breast cancer are prescribed long administraion of aromatase inhbitors.. these inhibitors usually induce musckloskeletal pains.
- Trial name
- NCT07662629
- Testing
- hyperbaric therapy and exercise, exercise
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Breast Neoplasm
GenetiKiT: Evaluation of an Educational Intervention on the Delivery of Genetics Services by Family Physicians
There is an urgent need for a knowledge translation strategy to facilitate the integration of genetics into family medicine, to improve the low knowledge base of most Canadian family physicians, ensure that the needs are met of…
- Trial name
- NCT00295529
- Testing
- Multifaceted educational intervention
- Where
- Canada
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Toronto
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