Clinical trials: Breath Holding
Sleep Disordered Breathing, Hypoxia
AT1R Blockade and Periodic Breathing During Sleep in Hypoxia
Sleep disordered breathing (SDB) is characterized by regular periods of no breathing (apnea) or low levels of breathing (hypopnea) and leads to repeated periods of low oxygenation, termed intermittent hypoxia that causes…
- Conditions
- Sleep Disordered Breathing, Hypoxia, Respiration; Sleep Disorder, Chemoreceptor Apnea
- Trial name
- NCT03335904
- Testing
- Hyperoxic Hypercapnic Ventilatory Response Test, Hypoxic Hypercapnic Ventilatory Response Test, Repeated Hypoxic Apneas
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Lung Tumor Resuction
Effects of Buteyko Breathing Technique Versus Incentive Spirometer on Breath Holding Time, Cardiopulmonary Endurance and Quality of Life in Patients With Post Lung Tumor Resection
The pulmonary complications are the major cause of morbidity and mortality following Lung surgeries. The Buteyko breathing technique is used for reversing the health condition such as poor breathing, mouth breathing and over…
- Trial name
- NCT05118347
- Testing
- Buteyko Breathing Technique
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Shahbaz Ahmad
Healthy
Load and Hold: Impact of 7-Day Creatine Monohydrate Loading on Breath-Hold Cycling Performance
The present study aims to investigate the effects of creatine monohydrate supplementation on maximal breath-hold exercise performance on a bicycle ergometer in trained breath-hold divers.
- Trial name
- BREATHE-C (NCT07233707)
- Testing
- Creatine Monohydrate
- Where
- Greece
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Breast Cancer
Large Segmentation Radiotherapy ± Deep Inspiration Breath Hold(DIBH) for Left Breast Cancer
The study is a single-center, prospective, non-randomized controlled study. The primary objective is to examine the clinical outcomes of utilizing Deep Inspiration Breath Hold (DIBH) in conjunction with hypo-fractionated…
- Trial name
- DLLEB (NCT06660628)
- Testing
- Large Segmentation Radiotherapy, DIBH, Surface guided radiation therapy
- Where
- China
- Volunteers
- 348 people
- Sponsor
- Peking Union Medical College Hospital
Lung Cancer, Metastatic Cancer
Combined Deep Inspiration Breath Hold (DIBH)-Expiration Planning Technique in Patients With Lung Tumors in Close Proximity to the Chest Wall
The purpose of this study is to evaluate a new radiation planning and treatment delivery technique called Deep Inspiration Breath Hold (DIBH) and expiration technique.
- Trial name
- NCT04507828
- Testing
- Treatment Planning using the DIBH Technique
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Indiana University
Breast Cancer, Adverse Effect of Radiation Therapy
Study to See Whether Breath-Hold Techniques During RT Are Effective in Helping to Improve Sparing of the Heart
The study hopes to determine whether patients with left-sided breast cancer are at an increased risk of cardiac changes due to radiation to the breast +/- Anthracycline-based chemotherapy +/- Herceptin and whether a deep…
- Trial name
- NCT02052102
- Testing
- Radiation therapy
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- AHS Cancer Control Alberta
Breast Cancer, Cardiac Event
Deep Inspiration Breath-hold Radiotherapy for Left-sided Breast Cancer
Postoperative breast radiotherapy (RT) has been associated with increased risk of heart toxicity. However, there is a lack of knowledge for radiation-induced early cardiovascular injury, especially for hypofractionated RT.
- Trial name
- NCT05200078
- Testing
- Deep inspiration breath-hold technique
- Where
- China
- Volunteers
- 166 people
- Sponsor
- Shu lian Wang
Healthy Amateur Divers
Effects of Voluntary Neck Extension on Cerebral Blood Flow, in Breath-hold Divers Ending an Apnoea of Two Minutes or More.
The aim of this study is to demonstrate the effect of the voluntary neck extension in the occurrence of an increase in the pulsatility index of the right internal carotid artery in the amateur diver, realizing an apnea of two…
- Trial name
- APNECK (NCT03210857)
- Testing
- apnea performing
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Lung Cancer (Diagnosis), Liver Cancer, Adult
A Study Evaluating a New Radiation Treatment Workflow (NGDS)
The purpose of this research is to evaluate the "Next Generation Delivery System" (NGDS) and determine if this machine will be more efficient at delivering radiation in shorter treatment time and better patient tolerance, with…
- Conditions
- Lung Cancer (Diagnosis), Liver Cancer, Adult, Pancreatic Cancer, Thoracic Cancers
- Trial name
- SPEED (NCT07824583)
- Testing
- Next Generation Delivery System (NGDS)
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Varian, a Siemens Healthineers Company
Lung Perfusion, Respiratory Physiology
Effects of Inspiratory vs Expiratory Breath-Hold on Lung Perfusion Measured by EIT Saline Indicator Method: A Self-Controlled Study
This study aims to compare lung perfusion distribution between inspiratory breath-hold and expiratory breath-hold phases using the saline indicator method combined with electrical impedance tomography (EIT).
- Conditions
- Lung Perfusion, Respiratory Physiology, Electrical Impedance Tomography, Ventilation-Perfusion Mismatch
- Trial name
- NCT07303972
- Testing
- Electrical Impedance Tomography Saline Indicator Procedure, Electrical Impedance Tomography Device
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Breast Cancer
Assessment of Ability of Breath Hold for Left-sided Breast Cancer Radiation Therapy to Reduce Side Effects to Heart
The purpose of this research study is to demonstrate that Deep Inspiration Breath Hold (DIBH), the technique used at the University of North Carolina (UNC) for left-side breast cancer radiation therapy, can reduce side effects to…
- Trial name
- NCT01849614
- Testing
- Cardiac SPECT perfusion scan
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Shock, Cardiogenic, Shock Hypovolemic
Clinical Validation of Algorithms for Mean Systemic Filling Pressure and Automated Cardiac Output
Prospective combined clinical validation of an algorithmic calculated mean systemic filling pressure (Pms-Nav) with the gold standard for Pms (Pms calculated from venous return curves during inspiratory hold procedures with…
- Conditions
- Shock, Cardiogenic, Shock Hypovolemic, Hypovolemia, Cardiac Failure
- Trial name
- PP3D (NCT04202432)
- Testing
- Mean systemic filling pressure
- Where
- Netherlands
- Volunteers
- 18 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Sport Physiology, Cognitive Performance
Cognitive Responses to Acute Breath-Hold Diving Training in Female Divers
This study aims to investigate the acute cognitive and physiological responses to breath-hold diving training in trained female divers.
- Trial name
- NCT07616804
- Testing
- Land-Based Breath-Hold Training, Water-Based Breath-Hold Training, Control Session
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Abdominal MRI
Single Breath Hold Abdominal MRI
The purpose of this study is to evaluate a single breath hold abdominal MRI protocol and compare the image quality of respiratory triggered 3D T1-weighted images against conventional breath hold images.
- Trial name
- NCT02434471
- Testing
- Respiratory-triggered T1w DISCO LAVA
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Duke University
Breast Cancer
Efficacity of Deep Inspiration Breath Hold and Intensity-modulated Radiotherapy in Preventing PErfusion Defect for Left Sided Breast Cancer (EDIPE)
Breast irradiation is known to cause radiation-induced heart disease (RIHD) many years later after radiotherapy. Recent studies suggest that RIHD could be an earlier complication and that subclinical cardiac injury can be…
- Trial name
- EDIPE (NCT05454553)
- Testing
- myocardial perfusion SPECT
- Where
- France
- Volunteers
- 58 people
- Sponsor
- Institut de cancérologie Strasbourg Europe
Neoplasm, Metastatic
Study of Breath-holding as a Means to Reduce Tumor Motion From Breathing
The purpose of this research study is to evaluate typical tumor motion caused by breathing using MRI and can help determine whether simple passive breathing and/or breath-holding could be used for the future treatment of similar…
- Trial name
- NCT00178477
- Testing
- MRI with breath-holding
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Rochester
Carcinoma, Non-Small-Cell Lung
Self-Gated Breath-Hold Technique for Helical Tomotherapy in Patients With Non-Small Cell Lung Cancer
Non-small cell lung cancer (NSCLC) is a disease that often cannot be surgically operated on. As a result, treating the tumor with radiation has become the main standard of treatment.
- Trial name
- NCT00129012
- Testing
- Tomotherapy
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- AHS Cancer Control Alberta
Left Ventricle Abnormality
Real-time MRI for Evaluating Cardiac Volumetry
This study will compare the accuracy of a real-time Cine sequence in assessing cardiac volumetry.
- Trial name
- NCT05221853
- Testing
- cardiovascular magnetic resonance
- Where
- United Kingdom
- Volunteers
- 570 people
- Sponsor
- University of Leicester
Pulmonary Disease, Chronic Obstructive
A Study to Assess the Pulmonary Distribution of Budesonide, Glycopyrronium and Formoterol Fumarate
This study is a 2 treatment period, single dose crossover, gamma scintigraphy study investigating the deposition in the lungs of a Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dose Inhaler.
- Trial name
- NCT03740373
- Testing
- BGF MDI (budesonide, glycopyrronium and formoterol fumarate) with 10 s breath hold, BGF MDI ((budesonide, glycopyrronium and formoterol fumarate) with 3 s breath hold
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Abdominal Cancer
Inhale and Exhale Breath Holds to Improve the Radiation Therapy Accuracy in People With Upper Abdominal Cancers
This is a prospective quality improvement study. The INEX RT P study will prospectively evaluate INEX RT R that optimizes radiation dose delivery to the target while minimizing dose to critical organs at risk (OAR) by treating…
- Trial name
- INEX-RT P (NCT07594691)
- Testing
- Simulation and treatment imaging
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University Health Network, Toronto