Clinical trials: Breathing-Related Sleep Disorder
Sleep Apnea, Continuous Positive Airway Pressure
Circadian Variations of Prostaglandin in Sleep Apnea
The purpose of this study is to evaluate the associations of circadian variations, sleep architecture, hypertension and prostanoids in the patients with sleep apnea.
- Conditions
- Sleep Apnea, Continuous Positive Airway Pressure, Prostaglandins, Circadian Variations
- Trial name
- NCT01096433
- Testing
- CPAP treatment
- Where
- Japan
- Volunteers
- 64 people
- Sponsor
- Kyoto University
Obstructive Sleep Apnea-hypopnea Syndrome
The Role of Inflammatory Markers in OSAHS-Related White Matter Lesions and Asymptomatic Lacunar Infarction
This retrospective observational study aims to investigate the potential role of inflammatory markers associated with Obstructive Sleep Apnoea-Hypopnoea Syndrome (OSAHS) in the pathogenesis of white matter lesions (WML) and…
- Trial name
- NCT07061990
- Testing
- Polysomnography (PSG), Brain Magnetic Resonance Imaging (MRI), Serum Inflammatory Marker Measurement
- Where
- China
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Yanpeng Li
Obstructive Sleep Apnoea, Primary Open-angle Glaucoma
PAIR Study-PAP And IOP Relationship: Study 2
Some people with Primary Open-angle Glaucoma (POAG) also suffer from Obstructive Sleep Apnoea (OSA), a common sleep disorder which is known to affect heart and blood vessels, and may contribute to glaucoma progression.
- Trial name
- PAIR2 (NCT03145129)
- Testing
- Continuous Positive Airway Pressure
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Obstructive Sleep Apnea Syndrome, Cleft Lip/Palate
A Study to Examine the Relationship Between Sleep Apnea and Cleft Lip/Palate
The study is to examine the relationship between sleep apnea and neurocognitive behaviors in children with cleft lip/palate. Describe the incidence and severity of obstructive sleep apnea in an unselected population of grade…
- Trial name
- NCT00156442
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Rochester
Obstructive Sleep Apnea, Hypertension
Assessment of Heart Rate Variability for Predicting Obstructive Sleep Apnea in Patients With Hypertension
This study aims to investigate the relationship between hypertension and obstructive sleep apnea (OSA) using heart rate variability (HRV) as a non-invasive biomarker of autonomic nervous system function.
- Trial name
- HRV-OSA-HTN (NCT07603583)
- Testing
- Polysomnography
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Kaohsiung Armed Forces General Hospital
OSA
Attitudes Toward Obstructive Sleep Apnea-Related Cause of Road Traffic Accidents in Thailand Through Well Prepared Educational Video
The goal of this descriptive, cross-sectional survey design is to determine the effect of public awareness video on the basic knowledge regarding sleep apnea syndrome or glaucoma and traffic accidents in normal population The…
- Trial name
- AOSARTA (NCT05734742)
- Testing
- Educational video
- Where
- Thailand
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Sleep Apnea Syndrome, Obstructive, Bruxism, Sleep-Related
Bruxism Induced by Obstructive Sleep Apnoea.
The relationship between obstructive sleep apnea (OSA), sleep bruxism, and temporomandibular disorders is becoming clearer, but data on how upper airway volume affects bruxism due to OSA is limited.
- Conditions
- Sleep Apnea Syndrome, Obstructive, Bruxism, Sleep-Related, Upper Respiratory Tract Illness
- Trial name
- OSA Bruxism (NCT07511946)
- Testing
- Upper airway volume assessment using Cone-Beam Computed Tomography (CBCT) and Polysomnography, Upper airway volume assessment using Cone-Beam Computed Tomography (CBCT)
- Where
- Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Sleep Apnea, Cardiovascular Diseases
Oxidative Stress and Cardiovascular Morbidity in Sleep Apnea-Hypopnea Syndrome (SAHS)
The purpose of this study is to compare the levels of 8-isoprostane and other oxidative stress biomarkers in plasma and condensed exhaled air between patients with SAHS and cardiovascular complications, patients with SAHS without…
- Trial name
- OSCAMSA (NCT00487929)
- Testing
- nasal CPAP
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Paz
Sleep Disorder; Breathing-Related, Cardiovascular Diseases
Minimally Invasive Detection of a Sleep Apnoea
Obstructive sleep apnoea (OSA) is characterised by recurrent nocturnal respiratory interruptions, resulting from the total or partial collapse of the upper respiratory ways.
- Conditions
- Sleep Disorder; Breathing-Related, Cardiovascular Diseases, Cardiovascular Risk Factor, Cardiovascular Complication
- Trial name
- KCG_SLEEP (NCT03760159)
- Testing
- Kinocardiography unintrusive recording
- Where
- Belgium
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Laparascopic Sleeve Gastrectomy, Obesity & Overweight
Impact Of Laparoscopic Sleeve Gastrectomy On Obesity-Related Comorbidities In Patients Over 65 Years
This study compares laparoscopic sleeve gastrectomy (a type of weight-loss surgery) with non-surgical care in adults aged 65 or older who have severe obesity and related health problems like type 2 diabetes, high blood pressure…
- Conditions
- Laparascopic Sleeve Gastrectomy, Obesity & Overweight, Obesity Type 2 Diabetes Mellitus, Obstructive Sleep Apnea (OSA)
- Trial name
- NCT07437716
- Testing
- Laparoscopic Sleeve Gastrectomy (LSG), Structured Dietary Counseling
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Diabetic Macular Edema, Sleep Apnea
Diabetic Macular Edema - Obstructive Sleep Apnea Relationship Study
The purpose of this study is to evaluate the relationship between DME and obstructive sleep apnea (OSA). OSA impacts millions of North Americans, many of whom are undiagnosed.
- Conditions
- Diabetic Macular Edema, Sleep Apnea, Non Proliferative Diabetic Retinopathy
- Trial name
- DME-OSA (NCT03597815)
- Testing
- Aflibercept 40 MG/ML [Eylea], OSA diagnostic test - overnight sleep study, CPAP therapy for OSA positive patients
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Uptown Eye Specialists
Sleep Apnea Syndromes
Sleep-related Breathing Disorders in Cardiological Outpatients
The purpose of this study is to determine the prevalence of sleep-related breathing disorders (SRBD) in clinically stable cardiologic outpatients of a German university clinic by means of polygraphy.
- Trial name
- SRBD-Cardio (NCT02693925)
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
Pulmonary Embolism, Sleep Apnea Syndrome (OSAS)
Impact of Sleep Related Breathing Disorders on Outcomes of Acute Pulmonary Embolism
This study aimsto compare short-termclinical outcomesand one-year recurrence rates in patients with acute pulmonary embolism with versus without sleep-disordered breathing, recruited from Alexandria MainUniversityHospital.
- Trial name
- NCT07356908
- Testing
- polysomnography
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Sleep Apnea
Evaluation of the Noga System: Detecting of Respiratory Related Sleep Disorders in Cardiac Patients
Medical literature has shown that 1 out of 2 patients that are admitted to the hospital as a cardiac patient, will be found suffering from sleep breathing disorders.
- Trial name
- NCT00800397
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- WideMed LTD.
Obstructive Sleep Apnea
This Research Project Studies the Relationship Between OSA and Nocturia.
The main goal of the study is to explore the relationship between obstructive sleep apnoea and nocturia.
- Trial name
- NCT06239883
- Testing
- Voiding diary
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Ostrava
Sleep Disorder; Breathing-Related, Pain, Postoperative
Comparison of Peritonsillar Infiltration of Tramadol Ketamine and Placebo on Pediatric Posttonsillectomy Pain
Adenotonsillectomy is one of the most common ambulatory surgical procedures performed to children. Tonsillectomy or adenotonsillectomy have a high incidence of postoperative pain.
- Conditions
- Sleep Disorder; Breathing-Related, Pain, Postoperative, Child, Only
- Trial name
- NCT03067103
- Testing
- Tramadol, Ketamine
- Where
- Brazil
- Volunteers
- 108 people
- Sponsor
- Universidade Federal de Goias
Acne, Bites
Implementation of a Minor Ailment Service in Community Pharmacy Practice
Self-care and self-medication are commonly the treatments of choice for the management of minor ailments. Minor ailments can be treated through community pharmacy using a Minor Ailment Service (MAS).
- Conditions
- Acne, Bites, Burns, Cold
- Trial name
- INDICA+PRO (NCT05247333)
- Testing
- Minor ailment service
- Where
- Spain
- Volunteers
- 20,987 people
- Sponsor
- Universidad de Granada
Obstructive Sleep Apnea (OSA), Metabolic Dysfunction-Associated Steatotic Liver Disease
FIB-4 Index, Sleep Apnea Severity, and Nocturnal Hypoxemia
This retrospective study evaluates whether the Fibrosis-4 (FIB-4) index is associated with the severity of obstructive sleep apnea (OSA) and nighttime oxygen desaturation.
- Trial name
- FIB-4-OSA (NCT07798518)
- Where
- Turkey (Türkiye)
- Volunteers
- 373 people
- Sponsor
- Hisar Intercontinental Hospital
Spinal Cord Injuries, Spine Disease
Outcomes Post Treatment: Impact on Motor Impairment of Sleep Efficiency in SCI (OPTIMISE SCI Trial)
This randomized clinical trial will compare three groups of individuals with cervical/thoracic, complete or incomplete spinal cord injury (SCI) that will undergo: (i) early CPAP therapy in the management of moderate-to-severe…
- Trial name
- NCT05473689
- Testing
- Continuous positive airway pressure (CPAP) therapy
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- University Health Network, Toronto
Obstructive Sleep Apnea, Obesity
The Relationship Between Obesity-related Molecular Typing and Traditional Chinese Medicine Constitution
Obesity is an epidemic and a growing problem in the world. There are numerous causes of obesity, the most novel and personalized of which is genetic inheritance.
- Trial name
- NCT04326244
- Testing
- blood test, genetic test, Constitution in Chinese Medicine Questionnaire
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Chang Gung Memorial Hospital