Clinical trials: Breathlessness
Asthma
Combined Effects of Inspiratory Muscles Training With Pilate Training in Asthma Patients
Asthma is a chronic (long-term) condition that affects the airways in the lungs. The airways are tubes that carry air in and out of your lungs. In asthma the airways can become inflamed and narrowed at times.
- Trial name
- NCT06762236
- Testing
- Pillatate Training
- Where
- Pakistan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Dyspnea, Sleep Quality
Visual and Auditory Stimulation in Intensive Care Patients
This study is a randomized controlled experimental clinical trial designed to investigate the effects of visual and auditory stimulation on dyspnea severity, sleep quality, and anxiety levels in patients receiving noninvasive…
- Conditions
- Dyspnea, Sleep Quality, Anxiety, Intensive Care Patients
- Trial name
- NCT07895030
- Testing
- The Northern Lights and White Noise
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Yalova
Parkinson Disease
Neural Control of Breathing in Parkinson's Disease
Breathing is a complex process, which can be controlled through voluntary command or neural control. Parkinson's disease (PD) is a progressive neurological disorder.
- Trial name
- NEURON-PD (NCT06074614)
- Testing
- Hypercapnic ventilatory response, Respiratory related evoked potential, Transcranial magnetic stimulation
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Dyspnea, Muscle Strain
Muscle Reflex Inhibition in Hypoxic Exercise
The goal of this interventional study is to compare muscle reflex function under settings of normoxia (normal oxygen level), acute hypoxia (brief oxygen-lack) and chronic hypoxia (long-duration exposure to oxygen-lack).
- Trial name
- NCT05619887
- Testing
- Fentanyl, Saline
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Asthma, COPD
Exhaled Breath Metabolomic Biomarkers in the Acutely Breathless Patient
An acute study carried out across three acute admissions units within Leicestershire. The study is aimed at discovery and validation of volatile organic compounds (VOCs) in exhaled breath.
- Conditions
- Asthma, COPD, Heart Failure, Community-acquired Pneumonia
- Trial name
- EMBER (NCT03672994)
- Where
- United Kingdom
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Breathing Pattern Disorder, Breathlessness
The Physiotherapy Assessment of Breathing Pattern Disorder
This study aims to evaluate a clinical tool called the Breathing Pattern Assessment Tool (BPAT), which is used by physiotherapists to assess breathing pattern disorder (BPD).
- Trial name
- PHAB (NCT07543588)
- Testing
- Assessment of Breathing Pattern- Breathing Pattern Assessment Tool
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Dyspnea, Unexplained Chronic Dyspnea
Establishing Clinical Utility for a New Diagnostic Test for Patients With Shortness of Breath
This study will collect high-quality data on how practicing specialist physicians, specifically cardiologists and pulmonologists, across the U.S.
- Trial name
- NCT04693793
- Testing
- Education Materials and Janssen Test
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Aging Disorder
Physical Impairments in Elderly Individuals
There are no studies in the literature reporting the dyspnea, posture, strength, physical activity, functional mobility and balance in elderly individuals.
- Trial name
- NCT06267625
- Testing
- Physical Evaluations of individuals
- Where
- Turkey (Türkiye)
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Chronic Obstructive Pulmonary Disease
Pennsylvania Study Of Chronic Obstructive Pulmonary Exacerbations
The overall purpose of PA-SCOPE is to determine why black and rural residents of Pennsylvania might be at higher risk for deadly, debilitating, and costly hospitalizations for chronic obstructive pulmonary disease (COPD)- and…
- Trial name
- PA-SCOPE (NCT00774176)
- Where
- 3 sites in United States
- Volunteers
- 1,066 people, healthy volunteers welcome
- Sponsor
- Temple University
Chronic Obstructive Pulmonary Disease
Effects Of of Pursed Lip Breathing and Coordinated Breathing in Adult Patients With COPD
COPD is the chronic lung condition characterized by the damage and enlargement of the air sacs in the lungs, leading to breathing difficulties. A blockage may develop, which traps air inside your lungs.
- Trial name
- NCT06459843
- Testing
- pursed lip breathing techniques, coordinated breathing technique
- Where
- Pakistan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Heart Failure, Dyspnea
Bedside Ultrasound Identifies Congestive Heart Failure
Patients often arrive to the Emergency Department with the chief complaint of shortness of breath. The cause of the shortness of breath may be due to many things, such as pneumonia, emphysema, a heart attack, heart failure, and…
- Trial name
- NCT00833144
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Emory University
Fatigue, Dyspnea
TaiChi-DTx for Treating Long Covid Symptoms
The randomized controlled trial will be conducted to evaluate the effectiveness of a Multi-domain Tai Chi Digital Therapy for treating the individuals suffering from the long term COVID-19 syndrome (Long COVID).
- Conditions
- Fatigue, Dyspnea, Cognitive Impairment, Muscle Pain
- Trial name
- TaiChi-DTx (NCT05419219)
- Testing
- the multi-domain Tai Chi Digital therapy Software Application
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tim Shi
Dyspnea, Pain
Non Opioid Treatment for Experimental Dyspnea
The purpose of this protocol is to test the effects of the non opioid nefopam on experimental dyspnea and on the counterirritation (ie inhibition of one pain by another pain) induced by dyspnea in healthy subjects.
- Trial name
- Nefopel (NCT01577407)
- Testing
- Nefopam
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lung Cancer
The Effect of Mindfulness-Based Breathing Exercises on Dyspnea, Symptom Control, and Quality of Life in Lung Cancer Patients Undergoing Chemotherapy
This research is designed to determine the effect of mindfulness-based breathing exercises on dyspnea, symptom control, and quality of life in lung cancer patients undergoing chemotherapy.
- Trial name
- NCT07520799
- Testing
- Mindfulness-Based Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Firat University
Dyspnea; Cardiac
Test-Retest Reliability of Cardiopulmonary Exercise Testing With Echocardiography
CPETecho is progressively employed in diagnostic settings for pathophysiological detection, offering comprehensive assessment of both pulmonary and cardiac functions.
- Trial name
- REPEATCPETecho (NCT07281534)
- Testing
- CPETecho
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ziekenhuis Oost-Limburg
Neonates, Respiratory Distress
Non-invasive Secondary Respiratory Support in Late Preterm and Term Infants
The aim of the present work is to compare between various modes of non-invasive respiratory support (including NCPAP, NIPPV, and NHFOV) as secondary respiratory support modes in late preterm and term neonates as regards the need…
- Conditions
- Neonates, Respiratory Distress, Non- Invasive Ventilation
- Trial name
- NCT07000071
- Testing
- NCPAP, NIPPV, NHFOV
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Chronic Obstructive Pulmonary Disease
Combined Effects of Blow Bottle Device and Postural Drainage in Moderate to Severe Elderly COPD Patients
It will be a randomized clinical trial. Age of selected subjects will be between 40 to 70 years. Data will be collected from Wazirabad institute of cardiology. There will be 2 groups i.e.
- Trial name
- NCT06476769
- Testing
- blow bottle technique, percussion
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Hypoxia, Normobaric Hypoxia
Effect of Acute Hypoxia on RIght VEntRicular Function in Healthy Adults.
More and more people are engaging in sports in the mountains, including individuals with heart or lung diseases. At the same time, such diseases are becoming more common in Switzerland.
- Conditions
- Hypoxia, Normobaric Hypoxia, Altitude Hypoxia, Right Heart Function
- Trial name
- RIVER-H (NCT07431567)
- Testing
- Normobaric Hypoxia
- Where
- 2 sites in Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mona Lichtblau
COPD
Urdu Translation, Validity and Reliability of Dyspnea 12 (D-12)
Dyspnea is a distressing symptom with pain like perception. The object of study is to translate a tool that measure overall dyspnea severity.
- Trial name
- NCT04879095
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Pulmonary Arteriovenous Malformations, Hereditary Hemorrhagic Telangiectasia
Cardiopulmonary Exercise Testing to Evaluate Pulmonary AVMs
Pulmonary arteriovenous malformations (PAVMs) are a rare vascular condition affecting the lungs. PAVMs lead to low blood oxygen levels, yet are very well tolerated by patients.
- Trial name
- NCT02436213
- Testing
- Cardiopulmonary exercise test, Blood test
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Imperial College London