Clinical trials: Bronchiolitis Obliterans, open to volunteers
Spinal Cord Injuries, Cerebral Palsy
Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions
This study will assess the benefits of using mobile health system designed for individuals with chronic and complex health conditions (such as those with Spinal Cord Injury,Cerebral Palsy, Spina Bifida, and Traumatic Brain…
- Conditions
- Spinal Cord Injuries, Cerebral Palsy, Spinal Dysraphism, Brain Injuries
- Trial name
- NCT02592291
- Testing
- MHealth
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Chronic Graft Versus Host Disease
Axatilimab for Sclerotic Chronic Graft-versus-Host Disease
This phase II trial tests how well axatilimab works in treating patients with thickening or hardening (sclerosis) of the skin related to chronic graft-versus-host disease after a donor stem cell transplant.
- Trial name
- NCT07011810
- Testing
- Axatilimab, Biospecimen Collection, Questionnaire Administration
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Fred Hutchinson Cancer Center
Endometritis; Chronic, Subfertility
The FLORA-project: in Search for the Microbial Cause of Chronic Endometritis and the Most Appropriate Treatment to Obtain a Successful Pregnancy IVF/ICSI
Chronic endometritis is an inflammatory condition of the endometrium. This inflammation can negatively affect fertility and pregnancy. The pathology is frequently (+-10%) observed in women with fertility problems.
- Trial name
- FLORA (NCT05337072)
- Testing
- Microbiome study
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Chronic Interstitial Cystitis, Bladder Pain Syndrome
Pain Type and Interstitial Cystitis/Bladder Pain Syndrome Treatment
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a severe pain condition affecting 3-8 million people in the United States lacking treatments that work.
- Conditions
- Chronic Interstitial Cystitis, Bladder Pain Syndrome, Painful Bladder Syndrome, Cystitis, Interstitial
- Trial name
- NCT06299683
- Testing
- Psychosocial Treatment, Pelvic Floor Physical Therapy
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Vanderbilt University Medical Center
Chronic Pain, Chronic Pain Syndrome
Collaboratory Treatment Pathway for Chronic Pain Patients.
In this multicenter randomized controlled trial, the aim is to evaluate the effectiveness of a standardized treatment pathway (STP) for patients referred to four participating pain clinics, by comparing it to treatment as usual…
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic (Non-malignant) Musculoskeletal Pain, Patients Referred to Multidisciplinary Pain Clinics
- Trial name
- PainPath (NCT07331766)
- Testing
- A collaborative treatment pathway for patients referred to multidisciplinary pain clinics in Norway, Treatment as usual
- Where
- 4 sites in Norway
- Volunteers
- 386 people
- Sponsor
- St. Olavs Hospital
Bronchiolitis Obliterable Syndrome
Forced Oscillatory Technique for Bronchiolitis Obliterans Syndrome After Allogeneic Bone Marrow Transplantation
Bronchiolitis obliterans syndrome (BOS) is a severe pulmonary complication following allogeneic hematopoietic stem cell transplantation (HSCT).
- Trial name
- NCT07730931
- Testing
- FOT - Forced Oscillation Technique
- Where
- Israel
- Volunteers
- 400 people
- Sponsor
- Hadassah Medical Organization
Gingivitis; Chronic
Effects of Using Miswak in Addition to Oral Hygiene Products in Patients With Gingivitis
This pilot study aims to evaluate the effects of miswak use on the oral biological environment by comparing biochemical parameters obtained from saliva and dental plaque samples collected from individuals who use miswak and…
- Trial name
- NCT07689786
- Testing
- Miswak, Toothpaste
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Periodontal Diseases, Periodontitis
HALP Score, Blood-Based Inflammatory Indices, and Salivary MMP-8 in Periodontal Disease and Healing After Non-Surgical Therapy
This observational clinical study aims to investigate the relationship between the HALP score (Hemoglobin × Albumin × Lymphocyte / Platelet), several blood-based inflammatory indices (including NLR, PLR, LMR, and SII), and…
- Conditions
- Periodontal Diseases, Periodontitis, Gingivitis; Chronic
- Trial name
- NCT07312045
- Testing
- Non-surgical Periodontal Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ömer Faruk Okumuş
Bronchiolitis Obliterans Syndrome, Chronic Lung Allograft Dysfunction
LAM-001 in Lung Transplant Recipients With Bronchiolitis Obliterans Syndrome.
The goal of this clinical trial is to learn about the safety and effectiveness of LAM-001 in patients who have developed bronchiolitis obliterans syndrome (BOS), a form of chronic rejection, after lung transplantation.
- Conditions
- Bronchiolitis Obliterans Syndrome, Chronic Lung Allograft Dysfunction, Lung Transplantation
- Trial name
- INSPO-BOS (NCT06018766)
- Testing
- LAM-001
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Steven Hays, MD
Chronic Graft Versus Host Disease
Tissue Immune Landscape of Graft Versus Host Disease After Allogeneic Stem Cell Transplantation (TIL-GVHD)
Graft versus Host Disease (GVHD) is frequent after allogeneic stem cell transplantation (alloSCT). GVHD occurs following 2 patterns : acute GVHD (aGVHD) or chronic GVHD (cGVHD).
- Trial name
- TIL-GVHD (NCT06247150)
- Testing
- Additional blood sample, cGVHD target tissue biopsy
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Bordeaux
Post-Surgical Pain, Chronic, Post-traumatic Pain, Chronic
Uncovering the Mechanism of Pain Relief by Peripheral Transcutaneous Magnetic Stimulation
This research aims to uncover the Mechanisms of pain relief through the FDA-cleared peripheral transcutaneous magnetic stimulation (pTMS) device by MagVenture.
- Trial name
- NCT07199361
- Testing
- Peripheral Transcutaneous Magnetic Stimulation from MagVenture
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Florida International University
Low Back Pain, Chronic
Person-Centered Lifestyle Redesign in Chronic Low Back Pain
This study is designed to examine the effects of a person-centered lifestyle intervention on pain, occupational performance, quality of life, disability, physical activity levels, and mental status in individuals with chronic low…
- Trial name
- NCT07163546
- Testing
- Lifestyle intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Hacettepe University
Chronic Graft Versus Host Disease
A Study of Belumosudil in Children With Chronic Graft Versus Host Disease (schoolROCK)
This is an open-label, single group, Phase 1/2, 1-arm study for treatment of children aged 1 to <18 years with active moderate-to-severe cGVHD that is refractory to or recurred after at least 2 prior lines of systemic therapy for…
- Trial name
- schoolROCK (NCT07116031)
- Testing
- Belumosudil
- Where
- 35 sites in United States, Belgium and 11 more
- Volunteers
- 37 people
- Sponsor
- Sanofi
Chronic Kidney Disease(CKD), Anemia, Kidney Disease, Chronic
Impact of Dapagliflozin in Anemic Chronic Kidney Disease Patients
Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor, primarily used in the management of type 2 diabetes mellitus.
- Trial name
- NCT06897605
- Testing
- Dapagliflozin (DAPA), Erythropoiesis Stimulating Agent
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Hepatitis B Virus Infection, Children
Entecavir With or Without Pegylated Interferon α-2b in Children Aged 3-6 Years With Immune-Tolerant Chronic Hepatitis B
This study aims to evaluate the efficacy and safety of entecavir monotherapy versus sequential entecavir plus pegylated interferon α-2b in achieving functional cure in immune-tolerant, HBeAg-positive children aged 3-6 years with…
- Conditions
- Hepatitis B Virus Infection, Children, Chronic Hepatitis B
- Trial name
- NCT07345624
- Testing
- Entecavir, Entecavir + Pegylated interferon α-2b
- Volunteers
- 80 people
- Sponsor
- Qing-Lei Zeng
Osteoarthritic Knee Pain
Freedom-1 Study for Chronic Knee Pain
To demonstrate the potential benefits and risk of active sub-threshold stimulation in the treatment of chronic knee pain as compared to subjects that did not have active stimulation.
- Trial name
- NCT03877653
- Testing
- Wireless neuromodulation
- Where
- 13 sites in United States
- Volunteers
- 100 people
- Sponsor
- Curonix LLC
Obesity and Obesity-related Medical Conditions, Spinal Cord Injury, Chronic
UTSW NORC Pilot Spinal Cord Injury Dietary Program
The goal of this observational study is to learn about the effects of a 9-week dietician-guided program modified from the National Diabetic Prevention Program (modified DPP-diet) in people with spinal cord injury on body…
- Trial name
- NCT06924177
- Testing
- Telehealth with dietician
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas Southwestern Medical Center
Chronic Graft Versus Host Disease
Belumosudil for the Pre-emptive Treatment of Patients With Chronic Graft Versus Host Disease
This phase II trial compares the effect of belumosudil to a placebo in treating patients with chronic graft versus host disease.
- Trial name
- NCT05996627
- Testing
- Belumosudil, Biospecimen Collection, Electronic Health Record Review
- Where
- 5 sites in United States
- Volunteers
- 82 people
- Sponsor
- Fred Hutchinson Cancer Center
Chronic Graft-versus-host Disease
Therapeutic Effects of Hydrogen on Steroid-refractory/or Steroid-dependent cGVHD
This study suggested that hydrogen has a potential as an effective and safe therapeutic agent on cGVHD.
- Trial name
- NCT02918188
- Testing
- Hydrogen
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Navy General Hospital, Beijing
Low Back Pain, Mechanical, Low Back Pain, Chronic
Effects of Foundation and Functional Inspiratory Muscle Training in Non-Specific Chronic Low Back Pain
This study was planned to examine the effects of basic and functional respiratory muscle training on pain, disability level, and functionality. In this study, participants will be randomly divided into 3 groups.
- Conditions
- Low Back Pain, Mechanical, Low Back Pain, Chronic, Non Specific Chronic Low Back Pain
- Trial name
- NCT06696300
- Testing
- Classical Physiotherapy Group, Foundation Inspiratory Muscle Training in Addition to Classical Physiotherapy, Functional Inspiratory Muscle Training Group in Addition to Classical Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kirsehir Ahi Evran Universitesi