Clinical trials: Bronchopulmonary Cancers
Chronic Lung Disease, Chronic Obstructive Pulmonary Disease
Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise
This study aims to more accurately assess cardiac function, ventilation and exercise capacity in a non-invasive fashion, and to better characterize exercise intolerance in the setting of three populations of individuals with…
- Conditions
- Chronic Lung Disease, Chronic Obstructive Pulmonary Disease, Acute Lymphoblastic Leukemia, Heart Transplant
- Trial name
- FLASHLITE (NCT05025774)
- Testing
- Physical activity
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Cystic Adenomatoid Malformation of Lung, Congenital, Bronchopulmonary Sequestration
Effect of Ultrasound-guided Erector Spinae Plane Block on Postoperative Pain and Sleep Quality of Infants With Congenital Pulmonary Cystic Disease After Thoracoscopic Surgery
This study intends to evaluate the effect of erector spinae plane block on postoperative analgesia and sleep quality in infants with congenital cystic pulmonary disease after thoracoscopic surgery, and provides reference for…
- Conditions
- Cystic Adenomatoid Malformation of Lung, Congenital, Bronchopulmonary Sequestration, Bronchogenic Cyst
- Trial name
- NCT06498583
- Testing
- Ropivacaine, erector spinae plane block, Incision infiltration of local anesthesia
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Lei Xiaoming
Metastatic Bronchopulmonary Cancer
Development of a Model to Predict the Risk of Venous Thromboembolic Events in Patients With Metastatic Bronchopulmonary Cancer
Venous thrombo-embolism (VTE) is a frequent and serious complication of cancer. However, predictive tools for VTE in cancer patients is lacking.
- Trial name
- LUCAAT (NCT04196790)
- Where
- 3 sites in France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Brest
the Rate of Participation in Screening for PBC
Experimentation With Screening for Bronchopulmonary Cancer and Primary Cardiovascular Prevention, Early Management of COPD and an Offer Exempted From Smoking Cessation
The study consists of recruiting a target population by sending a letter from the Regional Center for Cancer Screening in Ile de France.
- Trial name
- LUMASCAN-2 (NCT05440123)
- Testing
- screening for bronchopulmonary cancer
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Neuroendocrine Tumors
Peptide Receptor Radionuclide Therapy in the Treatment of Advanced, Non-resectable and/or Symptomatic Tumors With SSTR Overexpression
This is a non-randomized phase II , open label, comparative study. Patients with advanced non-resectable and/or progressive gastro-entero-pancreatic Neuroendocrine Tumours - GEP-NET, (G1, G2 and G3), Broncho-pulmonary Carcinoids…
- Trial name
- POLNETS_PRRT (NCT04029428)
- Testing
- 90Y-DOTATATE, (177Lu-DOTAOTyr3)Octreotate, 90Y DOTATATE and 177Lu DOTATATE (mix each of 50%)
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- University of Warmia and Mazury
Bronchial Cancer
Stereotactic Margins in Localized Bronchial Cancer (T1/T2a, N0)
Bronchopulmonary cancer is the first cause of mortality in the world. We want to update the margins used in stereotactic radiotherapy, in the context of localized lung cancer, of non-surgical management.
- Trial name
- Stereotactic (NCT05605236)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
Non Small Cell Lung Cancer Metastatic, Treatment Adverse Effect
Thyroid Dysfunction and Nivolumab Reponse in NSCLC
This is an observational, retrospective and monocentric study, conducted at the university Hospital of Brest The primary objective is to assess the association between the occurrence of thyroid dysfunction in patients treated…
- Conditions
- Non Small Cell Lung Cancer Metastatic, Treatment Adverse Effect, Thyroid Dysfunction, Immune Checkpoint Inhibitor
- Trial name
- THYRONIVO (NCT04470440)
- Where
- France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Brest
Neuroendocrine Tumours
A Retrospective Data Analysis of Therapy With PRRT Combined With Lanreotide Autogel® for Neuroendocrine Tumours
The objective of the PRELUDE study is to describe the use of lanreotide Autogel® (LAN ATG) combined with Peptide Receptor Radionuclide Therapy (PRRT) in the treatment of progressive neuroendocrine tumours located in the lung or…
- Trial name
- PRELUDE (NCT02788578)
- Where
- 12 sites in Australia, France and 3 more
- Volunteers
- 40 people
- Sponsor
- Ipsen
Lung Cancer
Wholebody MRI In Lung Cancer StagiNg
Magnetic Resonnace Imaging (MRI) and Positron Emission Tomography (PET) can be both used in detection of nodes in patients with cell lung cancer (NSCLC).
- Trial name
- WISLON (NCT02716051)
- Testing
- MRI, PET
- Where
- France
- Volunteers
- 36 people
- Sponsor
- University Hospital, Limoges
Cancer, Lung, Radiotherapy; Complications
Follow-up of Pulmonary Radiotoxicity for Bronchopulmonary Cancer.
assess the consequences of low doses of radiation delivered by the volumetric radiotherapy, on the respiratory capacity of patients treated for bronchopulmonary carcinoma, by a follow up of functional respiratory exploration.
- Trial name
- TEFRARC (NCT03931356)
- Testing
- Pulmonary function tests
- Where
- France
- Volunteers
- 39 people
- Sponsor
- University Hospital, Brest
Patients With Bronchopulmonary Cancer
Impact of Hospital Pharmacist on Drug Management in Patients With Bronchopulmonary Cancer
This is a prospective, non-interventional study to evaluate impact of hospital pharmacist on drug management in patients (only questionnaires) with bronchopulmonary cancer treated by Chemotherapy and/or Immunotherapy or Oral…
- Trial name
- IMPACTO (NCT06469957)
- Testing
- Questionnaires and data collection sheet
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Non Small Cell Lung Cancer
PEMBRO-K : Evaluation of Pembrolizumab Therapeutic Pharmacological Monitoring Benefit in NSCLC
Solid cancers and their therapeutic management remain a major public health problem due to their increasing prevalence and associated mortality. Among solid cancers, lung cancer ranks 4th among incident cancers.
- Trial name
- PEMBRO-K (NCT06195527)
- Where
- 2 sites in France
- Volunteers
- 75 people
- Sponsor
- University Hospital, Angers
Bronchopulmonary Cancers, Constitutional EGFR
Phenotypes Associated With Constitutional EGFR Pathogenic Variants
A small proportion of lung cancers are hereditary, i.e. caused by a constitutional pathogenic variant (PV). EGFR " Epidermal Growth Factor Receptor " is a major cancer predisposing gene, mainly via the T790M variant.
- Trial name
- EGFRench (NCT06562491)
- Volunteers
- 25 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Arthralgia
Evaluation of the Frequency of Occurrence of Joint Pain With Bevacizumab in Patients With Ovarian, Colorectal or Bronchopulmonary Cancer
Self-administered questionnaire survey to determine the presence or absence of joint pain during bevacizumab treatment for lung, ovarian, colorectal cancers.
- Trial name
- BEVARTHRALGIA2 (NCT03455907)
- Where
- 2 sites in France
- Volunteers
- 71 people
- Sponsor
- University Hospital, Lille
Non-Small Cell Bronchopulmonary Carcinoma or Melanoma
18FDG PET for Early Identification of Tumor Exhaust for Immunotherapy in Patients With Locally Advanced or Metastatic Non-Small Cell Bronchopulmonary Carcinoma or Melanoma
The hypothesis of this diagnostic performance study is that, for patients treated for immunotherapy-treated melanoma or NSCLC, some metabolic parameters of the 18FDG dual-point PET scan distinguish inflammatory pseudo-progression…
- Trial name
- FDG-IMMUN (NCT03584334)
- Testing
- 18FDG PET
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Antoine Lacassagne
Bronchopulmonary Dysplasia
Human Mesenchymal Stem Cells For Moderate and Severe Bronchopulmonary Dysplasia
This study is an open-label, single-center, dose escalation study to evaluate of safety and efficacy of human umbilical cord -derived mesenchymal stem cells (hUC-MSCs) in children with moderate and severe bronchopulmonary…
- Trial name
- NCT03601416
- Testing
- Transplantation of mesenchymal stem cell, No Transplantation of Mesenchymal Stem Cell
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Children's Hospital of Chongqing Medical University
Squamous Cell Lung Cancer
Prevalence of EGFR Mutations in epidermoïd Bronchopulmonary Cancers in Réunion Island
Lung cancer is the most common cancer in the world with 1.8 million estimated incident cases in 2012 (12.9% of diagnosed cancers) and 1.6 million deaths annually.
- Trial name
- EPIMURE (NCT04261725)
- Testing
- EGFR mutation
- Where
- 3 sites in Reunion
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Digestive System Neoplasms, Thoracic Neoplasms
Effectiveness of an Educational Intervention Aimed at Increasing the Emotional Competencies of Patients Under Surveillance After Antineoplastic Treatment of Oesogastric or Bronchopulmonary Cancer
Emotional skills are the ability to use emotions cleverly in daily life. Good emotional skills are associated with better mental and physical health in healthy and clinical populations.
- Trial name
- EmoVie_K2 (NCT04556344)
- Testing
- Emotional skills, Short free talk and relaxation
- Where
- France
- Volunteers
- 26 people
- Sponsor
- University Hospital, Lille
Bronchopulmonary Disease, Diagnoses Disease
Optimizing Bronchopulmonary Cancer Screening
The aim of this study is to evaluate the feasibility of performing a first screening for bronchopulmonary cancer by thoracic scanner in a French cohort within a dedicated, effective and structured network in the pilot centers…
- Trial name
- OPTI-DEPIST (NCT06439901)
- Testing
- Screening, Inclusion, Chest CTscan and follow-up
- Where
- 9 sites in France
- Volunteers
- 500 people
- Sponsor
- Institut Curie
Non Small Cell Lung Cancer
Efficacy Study of GEMOX Combination and Vinorelbine in NSCL Patients
Primary: ·To evaluate the activity of the combination of gemcitabine, oxaliplatin and vinorelbine as first line treatment in patients with non-small cell bronchopulmonary cancer Secondary: ·To evaluate the toxicity of the…
- Trial name
- GON (NCT00271271)
- Testing
- oxaliplatine / gemcitabine / Vinorelbine
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Sanofi