Clinical trials: Bronchoscopy,Oxygen
Hypoxia
High Flow Nasal OXygen Therapy in High Risk Patients of Hypoxia Undergoing Diagnostic BRONCHOscopy
The purpose of this study is to determine the efficacy and safety of nasal high flow oxygen therapy during diagnostic bronchoscopy.
- Trial name
- HFNOT (NCT01650974)
- Testing
- HFNOT
- Where
- South Korea
- Volunteers
- 136 people
- Sponsor
- Seoul National University Hospital
Conscious Sedation, Bronchoscopy
Incidence and Nature of Respiratory Impairment in Consecutive Patients Undergoing Bronchoscopy Under Conscious Sedation: A Pilot Study
This study aims to characterize airflow patterns during bronchoscopy under conscious sedation, and determine the incidence of obstructive and central respiratory events.
- Trial name
- NCT03886454
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Tufts Medical Center
Acute Hypoxemic Respiratory Failure, High-flow Nasal Cannula Oxygen
Modified HFNC Therapy for ARF Patients Undergoing Flexible Bronchoscopy
Acute respiratory failure (AFR) is a serious condition that requires prompt and appropriate intervention to prevent further deterioration and improve outcomes.
- Trial name
- NCT05759832
- Testing
- Modified HFNC oxygen therapy, Non-rebreathing reservoir mask
- Where
- 2 sites in China
- Volunteers
- 160 people
- Sponsor
- Beijing Chao Yang Hospital
NIRS
The Systemic and Brain Oxygen Stauration Change During Bronchoscopy
Bronchofiberoscopy is a widespread invasive intervention in clinical practice with a number of diagnostic and therapeutic indications. The Clinic of Pulmonary Medicine in Debrecen carries out nearly 2000 examinations a year.
- Trial name
- BFNIRS (NCT04002609)
- Testing
- oxygen
- Where
- Hungary
- Volunteers
- 92 people
- Sponsor
- University of Debrecen
Foreign Bodies, Tumor
High-flow Nasal Oxygen During Rigid Bronchoscopy Under General Anesthesia: a Randomized Controlled Trial
The aim of this study is to evaluate the effect of high-flow nasal cannula oxygen administration on apnea in patients undergoing general anesthesia with rigid bronchoscopy compared with standard anesthesia methods.
- Conditions
- Foreign Bodies, Tumor, Stenosis Trachea, Bronchus Tumour
- Trial name
- NCT03892408
- Testing
- Optiflow ™
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Yonsei University
Hypoxemia During EBUS Bronchoscopy
High - Flow Nasal Cannula Versus Conventional Nasal Cannula During Endobronchial Ultrasound Procedure
EBUS bronchoscopy is performed in most centers under local anesthesia and moderate sedation. Both the bronchoscopy itself and the sedation can lead to decreased ventilation and a drop in oxygen saturation in the body.
- Trial name
- NCT06637280
- Testing
- High - flow nasal cannula, Standard nasal cannula
- Where
- 4 sites in Croatia, Greece and 2 more
- Volunteers
- 150 people
- Sponsor
- The University Clinic of Pulmonary and Allergic Diseases Golnik
Bronchoscopy
Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Diagnostic Bronchoscopy
The purpose of this study is to investigate whether diagnostic bronchoscopy can be safely and potentially more effectively performed without the use of tracheal intubation or a supraglottic airway, under completely unobstructed…
- Trial name
- NCT03086408
- Testing
- THRIVE, Endotracheal tube or Supraglottic airway
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stanford University
Hypoxemia, Pneumonia
Effect of High-Flow Nasal Cannula Oxygen Therapy on Hypoxemia in Pediatric Sedated Bronchoscopy
Due to children's lower oxygen reserves and higher oxygen consumption, sedation can easily lead to respiratory adverse events such as hypoxemia.
- Conditions
- Hypoxemia, Pneumonia, Pulmonary Neoplasm
- Trial name
- NCT07563075
- Testing
- High-flow nasal cannula, Regular Nasal Cannula
- Where
- 4 sites in China
- Volunteers
- 430 people
- Sponsor
- Zhejiang University
Bradycardia, Hypoxemia
Nose-close and Abdomen-compression in Pediatric Flexible Bronchoscopy
The nasopharyngeal oxygen (NPO) with Nose-close (NC) and Abdomen-compression (AC) technique may use for support or rescue asphyxiated infants during Flexible bronchoscopy.
- Trial name
- NPO-NC-AC (NCT01629186)
- Testing
- NPO with Nose-close and Abdomen-compression
- Where
- Taiwan
- Volunteers
- 156 people
- Sponsor
- Cho-yu Chan, MD
Disorder Related to Lung Transplantation, Central Airway Stenosis
Hyperbaric Oxygen Therapy for Lung Transplantation
The objective of this study is to evaluate the effect of hyperbaric oxygen therapy (HBOT) on airway complications in post-lung transplant recipients with evidence of restricted levels of blood and oxygen in the airway tissue.
- Conditions
- Disorder Related to Lung Transplantation, Central Airway Stenosis, Airway Exudative Plaques, Airway Complications Post-Lung Transplantation
- Trial name
- NCT02363959
- Testing
- Hyperbaric Oxygen Therapy, Endobronchial Biopsy of Airway Epithelium
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Duke University
Central Airway Obstruction
To Investigate Airway Oxygen Concentrations During Rigid Bronchoscopy Procedures Performed With High Frequency Jet Ventilation
Thermal ablation (use of treatment modalities that generate heat) has become a widely used tool for treatment of central airway obstruction (e.g. laser, electrocautery, radiofrequency, and argon plasma coagulation).
- Trial name
- NCT05881863
- Testing
- No intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Minnesota
Respiratory Failure, Hypercapnic Acidosis
High Flow Oxygen Therapy in Patients Undergoing Bronchoscopy Under Sedation
A reduction of peripheral oxygen saturation (SpO2) commonly occurs during bronchoscopy and may be associated with both respiratory and cardiac adverse events.
- Trial name
- BroncHoFlow (NCT04728412)
- Testing
- High Flow Oxygen Therapy (HFOT)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Cardarelli Hospital
Lung Disease
Comparison of Propofol/Alfentanil With Propofol/Ketamine
A prospective, randomized, patient-blinded comparison of the safety and efficacy of conscious sedation by propofol/alfentanil with propofol/ketamine in patients undergoing flexible fiberoptic bronchoscopy.
- Trial name
- KET-001 (NCT02000206)
- Testing
- Propofol, Ketamine, Alfentanil
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Rabin Medical Center
Fiberoptic Bronchoscopy
50% Nitrous Oxide and 50% Oxygen (MEOPA) Conscious Sedation Versus Placebo in Fiberoptic Bronchoscopy
Fiberoptic bronchoscopy may generate pain, anxiety or cough and dyspnea. It may then induce discomfort and then run down its yield.
- Trial name
- NCT00392522
- Testing
- 50% Nitrous Oxide and 50% Oxygen (MEOPA)
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Hospices Civils de Lyon
Respiratory Disease
Comparison of Oxygen Adminstration by Nasal Cannula and High Flow Cannula During Bronchoscopy
Randomized controled trial to compare oxygen desaturation during fiberoptic bronchoscopy using oxygen administered with nasal prongs and high flow nasal cannula.
- Trial name
- NCT03976167
- Testing
- Oxygen administration with Common nasal cannula, Oxygen administration with high flow nasal cannula, device Airvo2 Fisher and Pykel
- Volunteers
- 108 people
- Sponsor
- Hospital Son Espases
Lung Cancer, Lymphadenopathy
Assessment of High Flow Nasal Cannula Oxygenation in EBUS Bronchoscopy
This study is a prospective randomised trial where a computer will randomly allocate patients to one of two possible methods of delivering oxygen during the procedure of bronchoscopy.
- Trial name
- AHOE (NCT03226964)
- Testing
- high flow nasal oxygen
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- University College Hospital Galway
Respiratory Insufficiency
Study of High Flow Nasal Cannula Oxygen for Bronchoscopy With Bronchoalveolar Lavage in ICU Patients
Bronchoscopy with bronchoalveolar lavage (BAL) is at risk for worsening hypoxemia in patients with acute respiratory failure (ARF). High-flow nasal cannula oxygen (HFNC) improves hypoxemia in ARF patients .
- Trial name
- Optibal (NCT02523573)
- Testing
- Adult ARF ICU patients needing BAL with HFNC
- Where
- 4 sites in France
- Volunteers
- 30 people
- Sponsor
- Hôpital Louis Mourier
Foreign Bodies, Tumor
The Effects of High-flow Nasal Oxygen on Oxygenation During Rigid Bronchoscopy Under General Anesthesia in Pediatric Patients
The aim of this study is to evaluate the effect of high-flow nasal cannula oxygen administration on maintenance of oxygenation and removal of carbon dioxide during apnoeic period in pediatric patients undergoing general…
- Conditions
- Foreign Bodies, Tumor, Stenosis of Trachea, Bronchus
- Trial name
- NCT03905733
- Testing
- Optiflow
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yonsei University
Acute Respiratory Failure, Bronchoscopy
HFNC During Bronchoscopy for Bronchoalveolar Lavage
The execution of diagnostic-therapeutic investigations by bronchial endoscopy can expose the patient to acute respiratory failure (ARF). In particular, the risk of hypoxemia is greater during broncho-alveolar lavage (BAL).
- Conditions
- Acute Respiratory Failure, Bronchoscopy, Bronchoalveolar Lavage
- Trial name
- NCT04016480
- Testing
- High Flow Nasal Cannula, Conventional Oxygen Therapy
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- University Magna Graecia
Bronchoscopy,Oxygen
Modified HFNC Oxygen in Patients Undergoing Bronchoscopy.
The purpose of this study is to determine whether the Modified High-flow nasal cannula is effective in the oxygen of the patients undergoing bronchoscopy.
- Trial name
- NCT02606188
- Testing
- Modified High-flow nasal cannula, nasal cannula
- Where
- China
- Volunteers
- 812 people, healthy volunteers welcome
- Sponsor
- Haichao Li