Clinical trials: Bronchoscopy；
Neuromuscular Blockade, Chronic Obstructive Pulmonary Disease
Comparison of Time to Extubation Using Sugammadex or Neostigmine
A prospective blinded randomized clinical trial to compare time to extubation using Sugammadex versus Neostigmine/glycopyrrolate as reversal agents after use of neuromuscular blockade agents in an outpatient bronchoscopy suite.
- Trial name
- NCT04606901
- Testing
- neostigmine/glycopyrrolate, sugammadex
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Temple University
Lung Cancer
The Lung PCA: A Multi-Dimensional Atlas of Pulmonary Premalignancy
This protocol pertains specifically to the prospective lung squamous cell carcinoma pre-malignant lesion (PML) cohort that will form a primary study group for the Lung Pre-Cancer Atlas.
- Trial name
- NCT03881098
- Testing
- Bronchoscopies, Sputum Sample, Venipuncture
- Where
- 2 sites in United States
- Volunteers
- 240 people
- Sponsor
- University of Colorado, Denver
Ultrasound Imaging, Supraglottic Airway Device
Ultrasound Imaging to Validate I-gel Placement in pediatrıc Patients
For nearly half a century, supraglottic airway devices (SGA) have been used in pediatric patients, which are more practical than face masks, facilitate oxygenation and ventilation without the need for endotracheal intubation, and…
- Conditions
- Ultrasound Imaging, Supraglottic Airway Device, Fiberoptic Bronchoscopy
- Trial name
- NCT04652466
- Testing
- farukcicekci2
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Lung Neoplasms, Bronchoscopy
Feasibility and Preliminary Performance of an AI Prototype for Digital ROSE During EBUS-TBNA and Peripheral TBNA: a Prospective Pilot Study (AI-ROSE-FEAS)
Rapid On-Site Evaluation (ROSE) of cytological slides obtained during EBUS-TBNA improves diagnostic yield by providing real-time adequacy assessment and preliminary diagnostic orientation after each needle pass.
- Conditions
- Lung Neoplasms, Bronchoscopy, AI (Artificial Intelligence), Mediastinal ( Chest) Masses
- Trial name
- AI-ROSE-FEAS (NCT07662967)
- Testing
- ROSE
- Volunteers
- 65 people
- Sponsor
- Azienda Ospedaliera di Rilievo Nazionale A.Cardarelli
Compare Operational Performance of Three Technology in Lung Models
The Assessment of the Feasibility and Operational Performance of Automated System Bronchoscopy in a Simulated Environment
Recruit 30 trainee physicians from 6 centers and compare their performance in operating lung models using automatic bronchoscopy, robotic bronchoscopy, and electromagnetic navigation bronchoscopy.
- Trial name
- NCT06741267
- Testing
- RBS, AB, ENB
- Where
- Chad
- Volunteers
- 30 people
- Sponsor
- Guangzhou Medical University
Sedation Method
Auditory Evoked Potential Monitoring on Bronchoscopy
To compare the difference of sedation monitoring for bronchoscopic examination monitoring by auditory evoked potentials (AEP) or Ramsay Sedation Scale (RSS) in mechanical ventilated patients.
- Trial name
- NCT01448811
- Testing
- AEP monitor, Ramsay Sedation Scale
- Where
- Taiwan
- Volunteers
- 37 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Lymphadenopathy, Tuberculosis
Diagnostic Accuracy of Polymerase Chain Reaction for Mycobacterium Tuberculosis Using EBUS-TBNA Samples
The purpose of this study is to compare the diagnostic efficacy of nested and realtime polymerase chain reaction for Mycobacterium tuberculosis using EBUS-TBNA samples in patients with isolated intrathoracic lymphadenopathy.
- Conditions
- Lymphadenopathy, Tuberculosis, Sarcoidosis
- Trial name
- NCT02497079
- Testing
- Nested PCR for formalin-fixed tissues, Nested PCR for fresh tissues, Real-time PCR for fresh tissues
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Pusan National University Hospital
Endotracheal Intubation
The Depth of Endotracheal Tube Insertion
Virtual experiment : comparing the new method with conventional method of determining the depth of endotracheal intubation.
- Trial name
- NCT03878797
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Gao Mei
Lung Cancer
Effectiveness of Bronchoscopic Interventions for Malignant Airway Obstruction
The goal of this clinical research study is learn about side effects and the success of bronchoscopies when performed in cancer patients with and without symptoms. This is an investigational study.
- Trial name
- NCT03326570
- Testing
- Medical Data Collection
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- M.D. Anderson Cancer Center
Bronchoscopy
The LUCENT Study - LUng Lesion Assessment Via BF-UCP190F for Central and Extended Nodal Targeting
The Olympus BF-UCP190F bronchoscope combines the reach of a thinner bronchoscope with the benefit of real-time ultrasound, enabling direct lesion visualization and sampling deeper into the lung.
- Trial name
- LUCENT (NCT07253727)
- Testing
- No Interventions
- Volunteers
- 200 people
- Sponsor
- Olympus Europe SE & Co. KG
Pulmonary Nodule, Solitary
Is Bronchoscopy Necessary in the Preoperative Workup of GGO Lung Cancer?(ECTOP-1005)
This study is one of Eastern Cooperative Thoracic Oncology Projects (ECTOP-1005). It aims to evaluate the role of flexible bronchoscopy in the pre-operative workup of ground glass opacity featured lung cancer.
- Trial name
- NCT03591445
- Testing
- Flexible Bronchoscopy
- Where
- China
- Volunteers
- 615 people
- Sponsor
- Fudan University
Sufentanil, Remifentanil
Comparison of Sufentanil, Fentanyl and Remifentanil in Combination With Midazolam During Bronchoscopy Under Conscious Sedation
The best opioid for bronchoscopy is still unclear.This randomized double-blind prospective study was conducted on a total of 60 patients who were randomly allocated into 3 groups: Group S received sufentanil 0.1 mcg/kg, Group F…
- Conditions
- Sufentanil, Remifentanil, Fentanyl, Bronchoscopy
- Trial name
- NCT03901716
- Testing
- Sufentanil, Fentanyl, Remifentanil
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Cancer, Lung, Cancer, Metastatic to Lung
Clinical Description of a Bronchoscopic Approach to Ablate Lung Nodules Using the Emprint™ Ablation Catheter
The purpose of this investigation is to characterize the safety and performance of the Emprint™ Ablation Catheter Kit with Thermosphere™ Technology in clinical use.
- Trial name
- NAVABLATE (NCT03569111)
- Testing
- Bronchoscopic ablation catheter
- Where
- 2 sites in Hong Kong, United Kingdom
- Volunteers
- 30 people
- Sponsor
- Medtronic - MITG
Lung Cancer
Validation of Rapid On-site Diagnostics in Early Stage Lung Cancer Sampling With a Higher Harmonic Generation Microscope
The aim of this study is to verify a new microscopic technique in diagnosing patients suspected of lung cancer. Patients will undergo navigational bronchoscopy or surgical resection as a part of standard of care.
- Trial name
- VALIDIAG (NCT06007261)
- Where
- Netherlands
- Volunteers
- 250 people
- Sponsor
- Radboud University Medical Center
Lung Cancer
Bronchoscopic Microwave Ablation of Lung Tissue
The primary purpose of this study is to evaluate the safety and feasibility of the Creo Medical MicroBlate™ Flex AB1 instrument used with the AB1 electrosurgical system in patients undergoing bronchoscopic microwave ablation of…
- Trial name
- AB1MALT (NCT05786625)
- Testing
- Ablation
- Where
- 2 sites in Netherlands, United Kingdom
- Volunteers
- 35 people
- Sponsor
- Creo Medical Limited
Acute Respiratory Failure
Lung Aeration After Flexible Bronchoscopy in Intubated Critically Ill Patients
In patients suffering from acute respiratory failure, ineffective cough and the consequent retention of secretions are common clinical problems, which often lead to the need for tracheostomy for the sole purpose of aspiration of…
- Trial name
- NCT05200494
- Testing
- Recruiting Maneuver
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University Magna Graecia
Anxiety
Effects of Sympathy and Touch on Anxiety of Patients Undergoing Fiberoptic Bronchoscopy
The purpose of this study is to evaluate the effect of verbal expression of sympathy and touch on anxiety of patients undergoing fiberoptic bronchoscopy
- Trial name
- NCT02000245
- Testing
- verbal expression for compassion, touch
- Where
- South Korea
- Volunteers
- 267 people
- Sponsor
- Seoul National University Hospital
Lung Neoplasm, Carcinoma, Non-Small-Cell Lung
Role of a Silicone Prosthesis to Prevent Airway Obstruction Recurrence in Lung Cancers
A tumoral obstruction of the main stem bronchus is frequently observed in the follow-up of lung cancers with a high impact on survival and quality of life of these patients.
- Trial name
- SPOC (NCT01064050)
- Testing
- silicone trachea-bronchial stent Dumon (Novatech)
- Where
- 13 sites in France
- Volunteers
- 75 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Fever, Pneumonia
The Impact of Antibiotic Prophylaxis on Incidence of Post-bronchoscopy Fever and Change of Serum Cytokines
Fever can develop after fiberoptic bronchoscopy (FB) in about 2.5 - 16 % of adult patients. We evaluated the impact of oral amoxicillin/clavulanate (AC) on incidence of postbronchoscopic fever and pneumonia.
- Trial name
- NCT01089218
- Testing
- oral amoxicillin/clavulanate 1g (875/125mg), control
- Volunteers
- 241 people
- Sponsor
- Seoul National University Hospital
Interstitial Lung Disease (ILD), Lung Biopsy
Robotic-Assisted Versus Conventional Bronchoscopy for Cryobiopsy in the Diagnosis of Interstitial Lung Disease
Interstitial lung disease (ILD) often requires histopathological confirmation when high-resolution computed tomography (HRCT) findings are inconclusive.
- Trial name
- RAB-ILD-RCT (NCT07500818)
- Testing
- Robotic-Assisted Bronchoscopy With Cone-Beam CT Guidance, Conventional Bronchoscopy With Fluoroscopy Guidance
- Where
- 2 sites in Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich