Clinical trials: Bronchoscopy；
Neuromuscular Blockade, Chronic Obstructive Pulmonary Disease
Comparison of Time to Extubation Using Sugammadex or Neostigmine
A prospective blinded randomized clinical trial to compare time to extubation using Sugammadex versus Neostigmine/glycopyrrolate as reversal agents after use of neuromuscular blockade agents in an outpatient bronchoscopy suite.
- Trial name
- NCT04606901
- Testing
- neostigmine/glycopyrrolate, sugammadex
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Temple University
Cancer, Lung, Cancer, Metastatic to Lung
Clinical Description of a Bronchoscopic Approach to Ablate Lung Nodules Using the Emprint™ Ablation Catheter
The purpose of this investigation is to characterize the safety and performance of the Emprint™ Ablation Catheter Kit with Thermosphere™ Technology in clinical use.
- Trial name
- NAVABLATE (NCT03569111)
- Testing
- Bronchoscopic ablation catheter
- Where
- 2 sites in Hong Kong, United Kingdom
- Volunteers
- 30 people
- Sponsor
- Medtronic - MITG
Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes
Topical Application of Cocaine HCl 4% and 10% on Safety and Efficacy in Local (Topical) Anesthesia
This study aims to evaluate topical application of Cocaine HCl 4% and 10% on safety and efficacy in local (topical) anesthesia for diagnostic procedures and surgeries on or through accessible mucous membranes of the nasal…
- Conditions
- Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes, of the Nasal Cavities
- Trial name
- NCT01746940
- Testing
- Cocaine HCl 4% Topical Solution, Cocaine HCl 10% Topical Solution
- Where
- 2 sites in United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Lannett Company, Inc.
Hypoxemia
Regimen of Alfentanil in Propofol Sedative Fibro-bronchoscopy
Alfentanil (Alf) is used in combination with Propofol (Pro) in fiber-bronchoscopy and in many other conscious sedation procedures.
- Trial name
- NCT01470170
- Testing
- Alfentanil, Normal saline, Targeted controlled infusion
- Where
- Taiwan
- Volunteers
- 173 people
- Sponsor
- Chang Gung Memorial Hospital
Lung Cancer
Piloting a Virtual Navigation (VN) System for Bronchoscopic Lung Nodule Sampling
The overall goal is to evaluate the role of a Virtual Navigation (VN) system (the Virtual Navigator) in the bronchoscopic evaluation and tissue sampling of lung cancer and other chest lesions at the Penn State Hershey Medical…
- Trial name
- NCT05599321
- Testing
- Virtual Navigation System
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Penn State University
Lung Neoplasms
POWER Study (Prospective Transbronchial Microwave + Robotic-Assisted Bronchoscopy)
This is a prospective, multicenter, single-arm study on transbronchial microwave ablation using the NEUWAVE FLEX Microwave Ablation System and Accessories on oligometastatic tumors in the peripheral lung, guided by the Auris…
- Trial name
- NCT05299606
- Testing
- Transbronchial Microwave Ablation
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 12 people
- Sponsor
- Ethicon, Inc.
Flexible Bronchoscopy
Target-Controlled Infusion of Propofol for Flexible Bronchoscopy Sedation
Flexible bronchoscopy (FB) sedation requires keeping sedative level in a narrow window to prevent over or under sedation. Sedative drug titration according to subjective adjustment by individual physician may cause unsteady drug…
- Trial name
- NCT01101477
- Testing
- TCI titration by different Cet.
- Where
- Taiwan
- Volunteers
- 144 people
- Sponsor
- Chang Gung Memorial Hospital
Sedation, Bronchoscopy
Patient-controlled Sedation With Propofol Versus Combined Sedation During Bronchoscopy
bronchoscopy - a randomized controlled trial" (EudraCT number: 2015-005274-38, protocol number: "BRONSE") is a phase IV single centre prospective randomized controlled trial with parallel groups.
- Trial name
- NCT03357393
- Testing
- Midazolam, Propofol-Lipuro, morphine-scopolamine
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Lena Nilsson
Bronchoscopy, Anesthesia
Prospective Non-interventional Evaluation of Intubation and Intensive Care Use of the New aScope™ 4 Broncho and aView
This study is designed as a prospective observational, non-controlled, non-interventional study. The aim of this study is to obtain a broad user perspective of the aScope™ 4 Broncho, focusing on the device functionalities within…
- Trial name
- NCT03294213
- Testing
- aScope 4 Broncho
- Where
- Germany
- Volunteers
- 176 people
- Sponsor
- Ambu A/S
Bronchoscopy
Dexmedetomidine for Sedation of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
Preventing hypoxemia is one of the major goal of studies for bronchoscopic sedation. Dexmedetomidine is a sedative agents via α2 adrenergic agonist, with little respiratory suppression.
- Trial name
- NCT03521505
- Testing
- Dexmedetomidine arm, Propofol arm
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Chang Gung Memorial Hospital
Conscious Sedation Failure During Procedure
Non-anesthesiologist-administered Propofol During the Flexible Bronchoscopy
Flexible bronchoscopy (FB) is a fundamental procedure for the diagnosis and treatment of respiratory diseases. Although midazolam is the recommended sedative agent by most guidelines, propofol has gained popularity due a short…
- Trial name
- NCT02820051
- Testing
- Transcutaneous CO2 monitor, Midazolam, Propofol
- Where
- Mexico
- Volunteers
- 102 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Bronchi--Diseases, Lung Diseases, Obstructive
Feasibility of Performing Peripheral Pulmonary Lesion Biopsy Using Robotic Bronchoscopy-Guided Cryoprobe
This research is being done to evaluate the feasibility, and biopsy quality, of using a 1.1mm disposable cryoprobe that is passed through the working channel of the Ion Robotic bronchoscope to collect biopsy tissue.
- Conditions
- Bronchi--Diseases, Lung Diseases, Obstructive, Lesions Mass
- Trial name
- NCT05399082
- Testing
- Cryoprobe biopsy, Forceps biopsy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Other Surgical Procedures
Video Double-Lumen Tube Prospective Randomized Study
The goal of this clinical research study is to learn how often a fiberoptic bronchoscopy (FOB -- also known as a fiberoptic scope procedure) needs to be used with a video double lumen tube (VDLT) during surgeries that require…
- Trial name
- NCT02429414
- Testing
- Non-Video Double Lumen Tube (DLT), Fiberoptic Bronchoscopy (FOB), Video Double Lumen Tube (VDLT)
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- M.D. Anderson Cancer Center
Bronchoscopy
Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Diagnostic Bronchoscopy
The purpose of this study is to investigate whether diagnostic bronchoscopy can be safely and potentially more effectively performed without the use of tracheal intubation or a supraglottic airway, under completely unobstructed…
- Trial name
- NCT03086408
- Testing
- THRIVE, Endotracheal tube or Supraglottic airway
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stanford University
Laminectomy
Intubation of Patients With an Unstable Cervical Spine Using the CMAC Device
The purpose of this study is to evaluate whether tracheal intubation with the CMAC device decreases the time required for intubation as compared to intubation with the fiberoptic bronchoscope in patients with an unstable cervical…
- Trial name
- NCT01113723
- Testing
- Fiberoptic bronchoscope, CMAC
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Cedars-Sinai Medical Center
Lung Diseases, Ultrasonography
Lung Ultrasonography vs Fiberoptic Bronchoscopy for Aiding Lung Collapse in Patient Using Double Lumen Tube
The study contains the result from a comparison of diagnostic outcomes about lung collapse by using lung ultrasonography as a new diagnostic test compares to fiberoptic bronchoscopy as the standard test.
- Conditions
- Lung Diseases, Ultrasonography, Fiberoptic Bronchoscopy, One Lung Ventilation
- Trial name
- NCT03314519
- Testing
- Lung ultrasonography by experienced anaesthesiologist, Fiberoptic bronchoscopy for double lumen tube's position
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Mahidol University
Sedation
Alternative Sedation During Bronchoscopy
This protocol hopes to determine whether the use of dexmedetomidine-ketamine can reduce the use of standard of care fentanyl-midazolam sedation during bronchoscopy.
- Trial name
- DEX (NCT01158820)
- Testing
- Dexmedetomidine load, Ketamine load, Midazolam load
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pennsylvania
Non-small Cell Lung Cancer (NSCLC), Lung Metastasis
Feasibility Study of Using Navigational Bronchoscopy to Perform PDT-Photofrin® in Unresectable Peripheral Lung Cancer
This research study is being conducted to assess the safety and feasibility of using a new developed bronchoscopic technology called electronavigational bronchoscopy to treat subjects with solid tumor in peripheral lung, who are…
- Trial name
- NCT02916745
- Testing
- Porfimer sodium, Fiber optic
- Where
- 7 sites in United States, Canada
- Volunteers
- 5 people
- Sponsor
- Concordia Laboratories Inc.
Flexible Bronchoscopy
Bispectral Index-guided Sedation for Flexible Bronchoscopy
With the advances of flexible bronchoscopy, like metallic stent, electrocautery and real time endobronchial ultrasound, the complexity and duration of procedures are increasing.
- Trial name
- NCT00789815
- Testing
- Bispectral index guide propofol infusion, Clinical-judged midazolam administration
- Where
- Taiwan
- Volunteers
- 500 people
- Sponsor
- Chang Gung Memorial Hospital
Disorder Related to Lung Transplantation, Central Airway Stenosis
Hyperbaric Oxygen Therapy for Lung Transplantation
The objective of this study is to evaluate the effect of hyperbaric oxygen therapy (HBOT) on airway complications in post-lung transplant recipients with evidence of restricted levels of blood and oxygen in the airway tissue.
- Conditions
- Disorder Related to Lung Transplantation, Central Airway Stenosis, Airway Exudative Plaques, Airway Complications Post-Lung Transplantation
- Trial name
- NCT02363959
- Testing
- Hyperbaric Oxygen Therapy, Endobronchial Biopsy of Airway Epithelium
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Duke University