Clinical trials: Bruises
Recruitment, Trauma
Recruitment Maneuver Using Lung Ultrasound in Trauma Patients
In trauma patients, the incidence of pulmonary contusion is frequent. Recruit maneuver using lung ultrasound could be improve oxygenation in trauma populatioin, howevere, there is no previous study.
- Trial name
- NCT04008758
- Testing
- Ultrasound
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Ajou University School of Medicine
Bruise, Contusion
A Study of Topical Arnica & Ledum on Bruise Reduction in HNV
Subjects will have a bruise induced. A pad containing either a placebo or active will be applied to the bruise. Photographs will be taken over the following days to record bruise healing.
- Trial name
- NCT04533269
- Testing
- Arnica montana, Ledum palustre
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Cearna, Inc.
Traumatic Brain Injury
The Effect of Single Dose D-Cycloserine on Cognitive Outcome in Moderate Traumatic Brain Injury (TBI) Patients
In this study of patients with moderate traumatic brain injury with frontal brain contusions patients will be randomized to treatment with a single dose of either D-cycloserine or placebo given 48-72 hours after injury.
- Trial name
- DCS (NCT01343862)
- Testing
- D-cycloserine
- Where
- 3 sites in Israel
- Volunteers
- 100 people
- Sponsor
- Hadassah Medical Organization
Traumatic Brain Injury (TBI), Attention Deficit Hyperactivity Disorder (ADHD)
Attention Intervention Management
This is a research study to learn if a computer-based intervention that provides direct attention and metacognitive strategy development can improve attention, memory, and executive control in adolescents with moderate-to-severe…
- Conditions
- Traumatic Brain Injury (TBI), Attention Deficit Hyperactivity Disorder (ADHD), Head Injury, Brain Concussion
- Trial name
- AIM (NCT01779427)
- Testing
- AIM
- Where
- United States
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Spinal Cord Injury, Spinal Cord Injuries
Testosterone Therapy With or Without Finasteride After Spinal Cord Injury: TRT-SCI Trial
Spinal cord injury (SCI) results in lower limb muscle loss, bone loss, and high fat mass that impede the recovery of physical function, increase bone fracture risk, and worsen health and quality of life.
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Injuries, Spinal Cord, Spinal Cord Contusion
- Trial name
- TRT-SCI (NCT07742553)
- Testing
- testosterone cypionate, finasteride
- Where
- 4 sites in United States
- Volunteers
- 300 people
- Sponsor
- VA Office of Research and Development
Lung Contusion
Lung Ultrasound Guided Fluid Balance Strategy in Patients with Lung Contusion
Lung contusion is caused by blunt chest trauma, explosion injuries or a shock wave associated with penetrating trauma. These injuries damage alveolar capillaries, so blood and other fluids accumulate in the lung tissue.
- Trial name
- NCT06586060
- Testing
- lung ultrasound guided fluid balance strategy, usual care guided fluid balance strategy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Injection Site Irritation, Injection Site Bruising
Comparison of Subcutaneous Injection of Normal Saline and Bacteriostatic Saline
This is a randomized, double-blind, single-center clinical trial comparing normal saline and bacteriostatic saline subcutaneous injection within a single subject.
- Conditions
- Injection Site Irritation, Injection Site Bruising, Injection Site Discomfort, Benzoic Acid Adverse Reaction
- Trial name
- NCT05109000
- Testing
- Sodium Chloride 0.9% Inj, Bacteriostatic Sodium Chloride 0.9 % INJECTION VIAL (ML)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Jeffrey Alan Klein, MD
Flail Chest, Rib Fractures
Mortality Causes in Rib Surgery Patients
This study retrospectively investigates the causes of mortality and morbidity in patients undergoing rib fracture surgery due to blunt trauma.
- Conditions
- Flail Chest, Rib Fractures, Thoracic Injuries, Pulmonary Contusion
- Trial name
- NCT06755723
- Testing
- Rib fractures manangement
- Volunteers
- 112 people
- Sponsor
- Caner İşevi, MD
Injection Fear, Injection Site Bruising
Testing Different Methods of Intramuscular Injection
The goal of this clinical trial is to compare in different injection techniques. The main question[s] it aims to answer are: Is there a difference between the pain levels due to needle insertion in the injection made with the HST…
- Conditions
- Injection Fear, Injection Site Bruising, Pain, Acute, Satisfaction, Patient
- Trial name
- NCT05577832
- Testing
- Helfer Skin Tap Technique, ShotBlocker Technique, Standard Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Muş Alparslan University
Acquired Bleeding Disorder, Trauma
Incidence/Magnitude-Haemorrhagic Progression-Cerebral Contusions and Identification (ID) of Safety Issues After Traumatic Brain Injury
This study is conducted in North America. The purpose of this study is to evaluate the occurrence and severity of bleeding in brain injury and to identify important safety issues following traumatic brain injury.
- Trial name
- NCT00124293
- Testing
- activated recombinant human factor VII
- Where
- 2 sites in United States, Canada
- Volunteers
- 63 people
- Sponsor
- Novo Nordisk A/S
Venous Insufficiency (Chronic)(Peripheral), Venous Reflux
Adrenaline Reduces Ecchymoses and Hematomas and Improves Quality of Life After Classic Saphenous Vein Stripping
Aim of the present study is to investigate the efficiency of adrenaline (epinephrine) used locally in reducing and avoiding post-operative formation of subcutaneous ecchymoses and hematomas, in comparison with traditional…
- Conditions
- Venous Insufficiency (Chronic)(Peripheral), Venous Reflux, Venous Insufficiency of Leg, Venous Stasis
- Trial name
- ARESQOLSAVES (NCT04758728)
- Testing
- Great saphenous vein stripping and varicectomies, Epinephrine Topical, normal saline
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Junior Doctors Network-Hellas
Ecchymosis
The Utility of Peri-operative Arnica Montana for Reduction of Ecchymosis in Rhinoplasty Surgery
Arnica montana is a homeopathic drug that is made in accordance with the official methods of the Homeopathic Pharmacopoeia of the United States (HPUS) and is commonly used by cosmetic surgeons throughout the world, although there…
- Trial name
- NCT01164644
- Testing
- Arnica montana
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Wisconsin, Madison
Edematous Fibrosclerotic Panniculopathy (EFP), Cellulite
Effects of Mitigation Treatments on Bruising of CCH-aaes Treatment of Buttock Cellulite
This study will investigate treatments that may mitigate bruising after QWO™ (Collagenase clostridium histolyticum [CCH]-aaes) treatment of cellulite in the buttocks.
- Trial name
- MOBI (NCT04677712)
- Testing
- CCH-aaes, Compression, Cold Packs
- Where
- 8 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Blunt Chest Trauma, Acute Respiratory Distress Syndrome
Statins and Selective Cyclooxygenase-2 Receptor Inhibitors in Blunt Chest Trauma
Background: Lung contusion affects 17%-25% of adult blunt trauma patients, and is the leading cause of death from blunt thoracic injury.
- Trial name
- NCT01623921
- Testing
- standard care treatment, Celecoxib, Rosuvastatin
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Lung Contusion
Respiratory Function Monitoring of Mechanical Ventilation in Patients With Chest Blunt Injury
The goal of this observational study is to learn about EIT in observing the application of lung protective ventilation strategies in patients with pulmonary contusion, particularly the impact on pulmonary ventilation blood flow…
- Trial name
- NCT06386120
- Testing
- PEEP setting strategy
- Volunteers
- 80 people
- Sponsor
- Peking University People's Hospital
Injection Site Bruising
Use of Tranexamic Acid in Facial Fillers
The overall purpose of this study is to evaluate the safety and efficacy of co-administration of tranexamic acid (TXA) with hyaluronic acid (HA) in reducing swelling, bruising and pain after facial injection.
- Trial name
- NCT04373603
- Testing
- Tranexamic acid, Saline, Hyaluronic acid
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Spinal Cord Contusion
Allogeneic Cord Blood Cells for Adults With Severe Acute Contusion Spinal Cord Injury
Study evaluates the safety and primary efficiency of systemic (i.v.) allogeneic human umbilical cord blood mononuclear cell infusions in patients with severe acute contusion spinal cord injury (ASIA A/B).
- Trial name
- NCT04331405
- Testing
- Human Allogeneic Umbilical Cord Blood Mononuclear Cells (hUCBMCs) systemic (i.v.) infusions
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- Sklifosovsky Institute of Emergency Care
Ecchymosis After Periorbital Rejuvenation With Botulinum Toxin Type A, Crow's Feet Lines
A Real-World Study on Effect of Hirudoid on Ecchymosis After Treatment of Crow's Feet With Botulinum Toxin Type A
Botulinum toxin type A (commonly referred to as 'Botox') injections are a treatment that dermatologists regularly use to smoothen wrinkles such as 'Crow's feet', to rejuvenate the skin surrounding the eye (the 'periorbital…
- Conditions
- Ecchymosis After Periorbital Rejuvenation With Botulinum Toxin Type A, Crow's Feet Lines, Lateral Canthal Lines, LCL
- Trial name
- NCT07388927
- Testing
- Hirudoid (heparinoids) ointment, 3mg/g
- Volunteers
- 48 people
- Sponsor
- DKSH Management (Thailand) Limited
Blunt Chest Trauma, Respiratory Failure
Combined Lung and Diaphragmatic Ultrasound to Predict Respiratory Failure in Blunt Chest Trauma
Blunt chest trauma is a leading cause of emergency hospital visits and can result in severe breathing complications such as hypoxemic respiratory failure.
- Conditions
- Blunt Chest Trauma, Respiratory Failure, Thoracic Injuries, Hypoxemic Respiratory Failure
- Trial name
- NCT07807566
- Volunteers
- 130 people
- Sponsor
- Assiut University
Pain, Postoperative, Bruising
Use of Tranexamic Acid in Blepharoplasties
The goal of this investigation is to assess whether or not there is a significant difference in the presence and/or degree of post-operative ecchymosis, pain, and edema between groups of patients undergoing upper lid…
- Trial name
- NCT04724772
- Testing
- Tranexamic acid injection
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University