Clinical trials: Bulging
Delayed Onset Muscle Soreness (DOMS), Inflammation
Effects of Immediate and Delayed Repeated Cold Exposure After Physical Exertion
The goal of this clinical trial is to learn if applying cold therapy can reduce swelling, inflammation, and pain after physical activity in adults who experience muscle soreness (Delayed Onset Muscle Soreness, or DOMS).
- Conditions
- Delayed Onset Muscle Soreness (DOMS), Inflammation, Muscle Pain, Muscle Damage
- Trial name
- NCT06813690
- Testing
- Cold Therapy with Axanova Cold Hot Pearls Maxi Pack
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences and Arts of Southern Switzerland
Spine Injury, Cord Injury, Spinal
The Outcome of Injured Cervical Spinal Cord With Uncontrolled Swelling Under Duraplasty
Overall Objective: To assess whether incorporating duraplasty alongside bony decompression enhances motor function outcomes in individuals following Traumatic Spinal Cord Injury (TSCI).
- Conditions
- Spine Injury, Cord Injury, Spinal, Cord Infarction Spinal, Incomplete Spinal Cord Injury
- Trial name
- NCT06552507
- Testing
- Duroplasty
- Where
- Taiwan
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Hip Disease
MRI-based 3D Hip Labrum and Cartilage Morphology in Patients With Hip Deformities Compared to Asymptomatic Volunteers
In this study, the investigators seek to describe the normal 3D hip joint morphology in asymptomatic volunteers and compare it to various hip joint deformities.
- Trial name
- NCT06095219
- Testing
- Non- contrast Magnetic Resonance Imaging (MRI) of the hip, Magnetic Resonance Imaging (MRI) of the hip with intra-articular contrast agent
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Facial Swelling, Tooth Position Anomalies
The Use of Platelet-rich-fibrin in Lower Third Molar Surgery.
The present study aims to analyze the effect of PRF (Platelet-rich-fibrin) in terms of facial swelling, trismus and pain after surgical removal of mandibular third molar (M3M) in a split-mouth randomized controlled clinical trial.
- Conditions
- Facial Swelling, Tooth Position Anomalies, Tooth, Impacted, Tooth Extraction Status Nos
- Trial name
- NCT06165692
- Testing
- PRF
- Where
- Italy
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Amerigo Giudice
Pain, Postoperative
Does Preventive Dexketoprofen Reduce Pain After Orthognathic Surgery
Background The purpose of this study was to evaluate the effect of a single-dose intravenous dexketoprofen administration for preventive analgesia on postoperative pain and reducing swelling in double jaw surgery.
- Trial name
- NCT05303688
- Testing
- iv dexketoprofen trometamol (Arveles 50mg/2mL; UFSA, İstanbul, Turkey), Steril Salin (control)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Pain, Postoperative, Post Operative Swelling
Effect Of Autologous Platelet Rich Fibrin On Post-Operative Complications And Healing Following The Extraction
As post-operative pain, infection inflammation and infections are the main complications after the surgical extraction of the lower third molar the aim of this study is to compare the healing effects of PRF administered…
- Conditions
- Pain, Postoperative, Post Operative Swelling, Trismus, Soft Tissue Healing
- Trial name
- PRF (NCT06609967)
- Testing
- application of PRF, application of conventional surgicel
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Tooth Extraction Status Nos
Efficacy of aPDT in Reducing Pain and Swelling Following Molar Extraction Surgery- Blinded Randomized Controlled Clinical Trial
This project aims to evaluate the effect of antimicrobial photodynamic therapy (aPDT) on the reduction of swelling and postoperative pain in lower molar extraction procedures.
- Trial name
- NCT03818906
- Testing
- Molar extraction - Control Group, aPDT + Molar Extraction - Test Group 1, Infrared + Molar Extraction - Test Group 2
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Postoperative Pain, Third Molar
Effect of Oral Magnesium on Anesthesia and Postoperative Analgesia After Surgical Removal of the Lower Third Molars.
The operation of the lower third molars is one of the most common oral surgery procedures in the world. The surgery is mostly done in local anesthesia which makes the surgery as pleasant as possible for the patient.
- Conditions
- Postoperative Pain, Third Molar, Postoperative Complications
- Trial name
- NCT03398382
- Testing
- Magnesium tablet group, Magnesium lozenge group
- Where
- 2 sites in Croatia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Daniel Jerković
Osteoarthritis, Muscle Pain
An Bioequivalence Study of Loxoprofen Sodium Patches in Healthy Volunteers
This study was a single-center, randomized, open-label, two-agent, two-cycle, double-cross bioequivalence trial.
- Conditions
- Osteoarthritis, Muscle Pain, Swelling Muscle
- Trial name
- NCT06510413
- Testing
- Loxoprofen Sodium Patches(reference product), Loxoprofen Sodium Patches(test product )
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Frontier Biotechnologies Inc.
Venous Occlusion
Venous Occlusion and Limb Swelling
Problems affecting the veins in the legs can cause discomfort and swelling. We want to see how artificially and reversibly blocking the leg veins affects swelling in the lower limb.
- Trial name
- NCT02241343
- Testing
- Venous occlusion (leg tourniquet, made in-house)
- Where
- United Kingdom
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Bimaxillary Protrusion
Evaluation of the Rate of En-masse Retraction in Orthodontic Patients With Maxillary Protrusion
There's a scarcity in literature concerning en-masse retraction and its effect on the rate of tooth movement. The purpose of this study is to determine, In orthodontic patients with maxillary protrusion, which form of mechanics…
- Trial name
- NCT04902430
- Testing
- Power chain and Crimpable hook for En-Masse Retraction, T- Loop
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Diabetic Retinopathy, Macular Edema
Dosing Study of Ranibizumab for Diabetic Retinal and Macular Edema
This study is to see whether treating diabetic retinal swelling with ranibizumab injections into the eye monthly is better than treating diabetic retinal swelling with ranibizumab injections into the eye less frequently.
- Trial name
- NCT01476449
- Testing
- Ranibizumab
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Retina Vitreous Associates of Florida
Periodontal Pocket, Pain
The Use of Submucosal Dexamethasone After Periodontal Surgery
The aim of this study is to evaluate the effectiveness of submucosal 8 mg (2 mL) dexamethasone on postoperative pain, swelling, chewing efficiency, trismus, healing, and discomfort after periodontal flap surgery
- Conditions
- Periodontal Pocket, Pain, Swelling/ Edema, Patient Satisfaction
- Trial name
- NCT06119893
- Testing
- submucosal 8 mg (2 mL) dexamethasone application, submucosal 2 mL 0.9% isotonic sodium chloride application
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Class II Division 1 Malocclusion, Class III Malocclusion
Efficiency of Canine Retraction Using Different Reactivation Intervals
Canine retraction after 1st premolar extracion into the extraction space is a routine treatment in orthodontics. Orthodontic patients requiring first premolar extraction, canine retraction and maximum anchorage were recruited for…
- Conditions
- Class II Division 1 Malocclusion, Class III Malocclusion, Bimaxillary Protrusion, Crowding, Tooth
- Trial name
- NCT04905004
- Testing
- Canine retraction
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Molar, Third, Third Molar Surgery
3D Evaluation of Postoperative Edema After Third Molar Surgery
Surgical removal of third molars is recognized as one of the most frequent procedures performed in oral surgery. Literature is rich in studies attempting to demonstrate the benefit of corticosteroids in third molar surgery…
- Conditions
- Molar, Third, Third Molar Surgery, Soft Tissue Swelling, Pain, Postoperative
- Trial name
- NCT05941130
- Testing
- Combination of corticosteroid (methylprednisolone - Medrol, 16mg Pfizer Laboratories) therapy and non-steroidal anti-inflammatory (Ibuprofen 600mg Mylan) therapy, Non-steroidal anti-inflammatory therapy (Ibuprofen 600mg Mylan)
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
PRF
The Efficacy of A-PRF+ on Postoperative Outcomes Following Surgical Removal of Impacted Mandibular Third Molars (A-PRF+: Advanced Platelet Rich Fibrin)
Objectives: This study aims to evaluate the effects of A-PRF+ on postoperative pain, swelling, and trismus after surgical removal of impacted mandibular third molars.
- Trial name
- A-PRF+ (NCT05824793)
- Testing
- A-PRF+
- Where
- Vietnam
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Lumbar Disc Herniation, Protrusion
Lumbar Kinematics in People With the Low Back Pain
This study evaluates the effect of lumbar disc herniation on kinematics in the lumbopelvic region during daily living activities.
- Conditions
- Lumbar Disc Herniation, Protrusion, Extrusion of Migrated Disc, Hernia
- Trial name
- NCT04417855
- Testing
- G-Walk
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Hypertension
A Study to Evaluate Methodologies for Measuring Swelling of the Leg and Ankle (MK-0000-106)(COMPLETED)
This study will evaluate methodologies for measuring pedal edema associated with calcium channel blockers in middle-aged and elderly subjects and patients with hypertension.
- Trial name
- NCT00789321
- Testing
- Comparator: amlodipine besylate
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Bimaxillary Protrusion
Evaluation of the Anchorage Loss During En-masse Retraction in Orthodontic Patients With Maxillary Protrusion
There is scarcity in literature regarding the effectiveness of friction and frictionless mechanics during ''En-masse retraction''technique on anchorage loss of posterior segment in orthodontic patients with maxillary protrusion.
- Trial name
- NCT04902456
- Testing
- Power chain and Crimpable hook fro En-masse Retraction, T-loop
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Malocclusion, Angle Class I, Bimaxillary Protrusion
3D Comparison of Anterior Teeth Retraction and Anchorage Control Between En-masse and Two-step Mechanics
The aim of this study is to compare en masse (EM) and two-step anterior teeth retraction (TSR) evaluated by means of three-dimensional images superimposition.
- Conditions
- Malocclusion, Angle Class I, Bimaxillary Protrusion, Orthodontic Space Closure
- Trial name
- NCT03903575
- Testing
- En masse anterior teeth retraction, Two-Step Retraction
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University