Clinical trials: Bupivacaine Adverse Reaction
Toxicity, Drug
Observation Study of the Pharmacokinetics of Adductor Canal Block
With the aging of the population, osteoarthritis of knees and hips become major orthopedic problems worldwide. Osteoarthritis of the knees and hips is associated with a significant pain problem and functional disability.
- Trial name
- NCT04916392
- Testing
- Liposomal bupivacaine
- Where
- Hong Kong
- Volunteers
- 10 people
- Sponsor
- The University of Hong Kong
Bupivacaine Adverse Reaction, Regional Anesthesia Morbidity
Sequential and Mixture Injection of Opioids and Hyperbaric Bupivacaine
Neuraxial anesthesia, especially the subarachnoid block, is the preferred method for LSCS. The intrathecal spread of local anesthetic drugs is unpredictable.
- Conditions
- Bupivacaine Adverse Reaction, Regional Anesthesia Morbidity, Cesarean Section Complications
- Trial name
- NCT04403724
- Testing
- Bupivacaine-fentanyl-Morphine.
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Assiut University
Anesthesia, Adverse Effect
Pharmacokinetics of BPV Following Bilateral US-guided TAP Block for C-section
The transversus abdominis plane block (TAP block) is an effective method of postoperative pain management after cesarean section (C-section).
- Conditions
- Anesthesia, Adverse Effect, Cesarean Section, Transversus Abdominis Plane Block
- Trial name
- NCT03006042
- Testing
- Bupivacaine
- Volunteers
- 17 people
- Sponsor
- University Tunis El Manar
Adverse Reaction to Spinal Anesthetic, Maternal Care for Cervical Incompetence
Chloroprocaine Spinal Anesthesia for Cervical Cerclage (CP Spinal)
This study aims to determine whether or not spinal anesthesia with the local anesthetic drug, chloroprocaine, wears off faster than the local anesthetic drug, bupivacaine, and results in faster discharge from the post-anesthesia…
- Trial name
- NCT02862912
- Testing
- Chloroprocaine, Bupivacaine, Fentanyl
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Columbia University
Hepatectomy, Analgesia, Epidural
Bupivacaine Levels in Liver Resection Patients
Bupivacaine is a local anesthetic commonly used to manage postoperative pain. Liver resection patients typically have an epidural catheter placed preoperatively through which they receive a continuous infusion of bupivacaine and…
- Trial name
- NCT03145805
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Jessica Burjorjee, MD, FRCPC
Myotoxicity
Effects of Postoperative Analgesic Modalities on Plasma Creatine Phosphokinase(CPK) Levels After Knee Artroplasty
Regional anesthesia and analgesia technics are widely and securely used during orthopedic surgery. Interfascial plane blocks are the latest used ones for analgesia.
- Trial name
- NCT05505890
- Testing
- suprainguinal fascia iliaca block
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Samsun University
Obstetric Anesthesia Problems, Bupivacaine Adverse Reaction
Thoraco Lumbar Vertebral Length and Bupivacaine Dosage in C-Section
Our hypothesis is that the bupivacaine dose determined according to the thoracolumbar vertebral body length (VBL) is more effective in achieving a lower hypotension rate during spinal anesthesia for cesarean delivery than the…
- Trial name
- bupivacaine (NCT06869434)
- Testing
- Group VBL (Thoracolumbal vertebral body length) received 0.2 mg x VBL cm of %0.5 hyperbaric bupivacaine, Group FD (fixed dose) received a volume of 0.5% hyperbaric bupivacaine based on a dose calculated according to the patient's height 0.065 mg/cm, Group AD (adjusted dosage) got intrathecal heavy bupivacaine (0.5%) tailored to the patient's height and weight.
- Where
- Turkey (Türkiye)
- Volunteers
- 446 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Spinal Anesthesia, Cardiac Toxicity
Cardiovascular Effects of Intrathecal Hyperbaric Prilocaine or Bupivacaine in Surgery Under Spinal Anesthesia
Spinal anesthesia remains a mainstay in lower limbs- as in day-case surgeries as well. It consists in injecting a local anesthetic drug into the intrathecal space of a patient's spinal canal.
- Trial name
- NCT05751148
- Testing
- Hyperbaric bupivacaïne, Hyperbaric prilocaïne
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Pregnant Women Who Requested Epidural Analgesia in the Early Stage of Labor
Onset of Labour Epidural Analgesia With Different Concentration Bupivacaine and Different Doses of Sufentanyl
This study aimed to compare the effects of three commonly used combination doses on the onset time and adverse reactions.
- Trial name
- NCT03395600
- Testing
- B1S5, B125S5, B1S10
- Where
- China
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Fudan University
Anesthesia; Adverse Effect, Spinal and Epidural, Anaesthetic Complication Neurological
Neurotoxicity of Spinal Anesthesia With Ropivacaine and Bupivacaine
Consenting patients, scheduled for orthopaedic surgery under spinal anesthesia will be randomly assigned (1:1) to receive ropivacaine or bupivacaine as a single shot before the start of surgery, followed by bolus doses of the…
- Trial name
- BuRoNe (NCT03293472)
- Testing
- Ropivacaine, Bupivacaine
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- University of Rzeszow
Anesthesia, Bupivacaine Adverse Reaction
Bupivacaine Levels After ESPB
Erector Spinae Plane Block (ESPB) is a regional anesthesia technique that is used for as a part of multimodal analgesia. Bupivacaine is one of the local anesthetic drugs and it is applied for ESPB.
- Trial name
- NCT04239053
- Testing
- Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 17 people
- Sponsor
- Maltepe University