Clinical trials: Burn Injuries
Burns
Validity and Reliability of Arabic Version of Michigan Hand Questionnaire in Assessment of Hand Function Post-burn
The purpose of the study will to test the: Face validity of Arabic version of Michigan Hand Outcomes Questionnaire in assessment of hand function post burn.
- Trial name
- NCT07614971
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Burn Scar
Efficacy of Spray Silicone in Alteration of Burn Scar
In a burn population, conduct a prospective, double-blinded, randomized, controlled clinical trial to determine the ability of spray silicone to alter the physical characteristics of burn scar compared to a placebo.
- Trial name
- NCT01075165
- Testing
- silicone spray, saline spray
- Where
- 2 sites in United States
- Sponsor
- United States Army Institute of Surgical Research
Retinal Light Damage, Photic Retinopathy
OCTA Evaluated the Efficacy of Glucocorticoid Retrobulbar Injection in Retinal Photo-injury
The goal of this retrospective observational study is to evaluate the effectiveness of retrobulbar glucocorticoid injection in patients with retinal photo-injury.
- Conditions
- Retinal Light Damage, Photic Retinopathy, Photic Maculopathy
- Trial name
- NCT07869511
- Testing
- retrobulbar injection of glucocorticoid
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Burns
Investigation of Thermal Injury on Intestinal Permeability in Both Thermal Injury and Healthy Participants
This longitudinal, prospective study aims to establish the magnitude and time course of changes in intestinal permeability; establish the optimal method for assessment of intestinal permeability in thermally injured participants…
- Trial name
- NCT03242434
- Testing
- Lactulose and Mannitol solution, Sucralose
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Whole Body Vibration, Virtual Reality
Whole Body Vibration and Virtual Reailtry on Quadriceps Strength and Activity of Daily Living in Children With Burn
Burns are injuries that can have both local and systemic effects and are brought on by biological, chemical, electrical, and physical factors.
- Trial name
- NCT06473311
- Testing
- whole bady vibration and virtual reality
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Cross-Sectional Studies
Burn Out and Quality of Life at French General Practioners
The suffering of caregivers is constantly increasing. General medicine, because of its primary role in primary care, is particularly exposed to the risk of burn-out and must protect itself.
- Trial name
- NCT04136899
- Testing
- Dukes scale
- Where
- France
- Volunteers
- 1,100 people
- Sponsor
- Albert TRINH-DUC
Burns, Burn Injury
Predictive Role of Glucose/Potassium Ratio on Mortality in Major Burns.
The aim of this observational study is to investigate the role of the glucose-potassium ratio in predicting mortality in patients with major burn trauma.
- Conditions
- Burns, Burn Injury, Inhalation Injury
- Trial name
- NCT06561282
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Konya Meram State Hospital
Burns
Determination of Nerve Growth Factor (NGF) Expression in Pediatric Patients With Severe Burns: a Pilot Study
The goal of this observational study is to determine the blood values of NGF in severely burned patients, to describe any changes over time and finally to correlate the expression of NGF to the severity of the burn.
- Trial name
- NCT05751174
- Testing
- pediatric patients affected by severe burns
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Burns, Wound Heal
Burn Validation Study
The purpose of this study is to validate the algorithm for burn healing assessment by the Spectral MD DeepView device which would provide burn healing potential assessment.
- Conditions
- Burns, Wound Heal, Wounds and Injuries
- Trial name
- BVS (NCT06131203)
- Testing
- DeepView SnapShot Portable (DV-SSP)
- Where
- 21 sites in United States
- Volunteers
- 274 people
- Sponsor
- SpectralMD
Burns, Intoxication
Efficacy and Safety of Rheosorbilact® Solution for Infusion, in a Complex Therapy of Burns
This study evaluates the efficacy and safety of Rheosorbilact®, solution for infusion ("Yuria-Pharm" LLC), in comparison with Ringer's Lactate, solution for infusion, in a complex therapy of burns.
- Trial name
- NCT04152096
- Testing
- Rheosorbilact®, Ringer lactate
- Where
- 5 sites in Kazakhstan, Moldova and 2 more
- Volunteers
- 118 people
- Sponsor
- Yuria-Pharm
Acute Burns
Using Autologous Platelet Rich Plasma (PRP) Gel to Treat Deep 2nd and 3rd Degree Burns
This study will demonstrate the safety of the application of autologous platelet rich plasma (PRP) gel following excision and autologous skin grafting of acute deep 2nd and 3rd degree burns.
- Trial name
- NCT01843686
- Testing
- Magellan®
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Arteriocyte, Inc.
Burns
Child's Adipose Cells: Capacity of Tissue Regeneration
The beneficial effect related to the administration of adipose tissue-derived stromal cells (ADSC) is demonstrated in various situations of physiological and pathological wound healing, thus opening a new field for cell therapy.
- Trial name
- cicASChild (NCT02779205)
- Testing
- adipose tissue sample
- Where
- France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Toulouse
Stem Cell Media, Hypertrophic Scar
Regenerative Effects of Human Stem Cell Media After Laser Therapy in Hypertrophic Scar
The purpose of this study was to determine the effect of combined treatment using nonablative laser and human stem cell media (HSCM) on the regeneration of hypertrophic scars that occurred after burns.
- Conditions
- Stem Cell Media, Hypertrophic Scar, Regeneration
- Trial name
- NCT05004779
- Testing
- human stem cell conditioned media was applied after non-ablative laser therapy, normal saline was applied after non ablative laser therapy
- Volunteers
- 30 people
- Sponsor
- Hangang Sacred Heart Hospital
Smoking Behaviors
Heat-not-burn Tobacco Product to Aid in Switching From Combustible to Noncombustible Nicotine (IQOS)
A novel heat-not-burn tobacco product (IQOS) will be provided to smokers, compared against a (cigarette) smoking as usual period in counter-balanced order in a cross-over design.
- Trial name
- IQOS (NCT04861428)
- Testing
- IQOS, Smoking as Usual
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Smoke Inhalation, Exposure, Inhalation
Lung Cancer Screening CT for Firefighters
Firefighters are at increased risk for cancer due to exposure to carcinogenic substances. Current lung cancer screening guidelines are predominantly based on smoking history and do not take into account high risk occupational…
- Conditions
- Smoke Inhalation, Exposure, Inhalation, Exposure to Pollution, Exposure Occupational
- Trial name
- NCT06836414
- Testing
- Low-dose Computerized tomography (CT) of Chest, Questionnaires, Medical History
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Burn, Thermal
StrataGraft® Skin Tissue in the Promotion of Autologous Skin Regeneration of Complex Skin Defects Due to Thermal Burns That Contain Intact Dermal Elements
About 70 participants will be enrolled. They will have complex skin defects because of burns caused by heat. The burns will: be on 3-49% of the participant's total body surface area (TBSA) require surgery for skin replacement…
- Trial name
- NCT03005106
- Testing
- StrataGraft Skin Tissue, Autograft
- Where
- 16 sites in United States
- Volunteers
- 71 people
- Sponsor
- Stratatech, a Mallinckrodt Company
Resuscitation, Burn
Optimizing Fluid Resuscitation in Adults With Major Burns: A Randomized Trial of Burn Navigator™ Versus Parkland Formula
Burn injuries affecting ≥20% TBSA trigger major fluid shifts requiring aggressive fluid resuscitation to prevent burn shock. Traditional formulas such as the Parkland and Modified Brooke estimate initial 24-hour fluid needs, but…
- Trial name
- FLARE (NCT07307599)
- Testing
- Burn Navigator, Resuscitation (Voluven)
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Alnas Hospital
Burns
Intraoperative Low-dose Ketamine Infusion as the Main Analgesic in Burn Patients
The purpose of this study is to determine whether a low-dose ketamine infusion can be used as the main intra-operative analgesic in different burn patients, and thereby reduce the total intra-operative opioid requirement.
- Trial name
- NCT03049930
- Testing
- Ketamine, Sodium chloride
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Loyola University
Burn Injury, Procedural Anxiety
Effect of Short-Video Distraction During Burn Dressing on Anxiety, Pain, and Fear in Children
Burn dressing procedures can cause pain, anxiety, and fear in children. Distraction techniques may help children cope with these procedures and improve their comfort.
- Trial name
- BURN-VIDEO (NCT07906834)
- Testing
- Short-Video Distraction
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Samsun University
Burn Injury, Body Temperature Regulation
The Effect of Simulated Burn Injury on Post Exercise Recovery in Hot Environments
Burn survivors have difficulty thermoregulating due to reduced skin blood flow and sweating responses at the grafted sites. It has been previously shown that this impaired heat dissipation results in burn survivors experiencing…
- Conditions
- Burn Injury, Body Temperature Regulation, Cardiovascular Physiology
- Trial name
- HSR (NCT07050264)
- Testing
- Simulated burn injury via application of absorbent and impermeable material over 60% of the body
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center