Clinical trials: Burn Pit Exposure
Lung Cancer Screening, Military Service-related Environmental and Occupational Exposures
Personalizing Veterans' Lung Cancer Screening and Diagnosis
Lung cancer screening with low-dose chest computed tomography (CT) is currently recommended for high-risk individuals who are 50 to 80 years old, have smoked cigarettes for at least 20 pack-years, and currently smoke or quit…
- Conditions
- Lung Cancer Screening, Military Service-related Environmental and Occupational Exposures, Cancer Survivor, Family History of Lung Cancer
- Trial name
- MAS-EXPAND (NCT07838519)
- Testing
- Low-dose computed tomography
- Where
- 7 sites in United States
- Volunteers
- 1,400 people
- Sponsor
- VA Office of Research and Development
Burn Pit Exposure
Tele-Exercise for MERP
During Operations Desert Shield and Desert Storm, Veterans in combat were exposed to a variety of airborne hazards, including oil well fire smoke, emissions from burn pits, and other substances associated with negative health…
- Trial name
- TEMPO (NCT07018466)
- Testing
- Tele-exercise, Standard of Care
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
PFAS, Environmental Exposures
Use of Bile Acid Binding Resins to Decrease PFAS Levels Via Colesevalem in Veterans Study
The goal of this study is to test the efficacy and feasibility of Colesevelam administration (50% of the recommended dose) to reduce serum PFAS concentration in the Veteran population who have serum PFAS levels that exceed the…
- Conditions
- PFAS, Environmental Exposures, Occupational Exposure to Chemicals, Military Exposure
- Trial name
- PAVERS (NCT07592858)
- Testing
- Colesevelam
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Burn Pit Exposure, Airborne Hazard Exposure
Project PHOENIX: Molecular Signatures of Burn Pit Exposure
Project PHOENIX is an observational clinical research study designed to characterize molecular, genomic, cellular, and functional features in blood specimens from former U.S.
- Conditions
- Burn Pit Exposure, Airborne Hazard Exposure, Veteran Health, Deployment-Related Toxic Exposure
- Trial name
- PHOENIX (NCT07562243)
- Testing
- Prior Burn Pit Exposure, No Known Burn Pit Exposure
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Creative Medical Technology Holdings Inc
Open Burn Pit Exposure
DNA Methylation Markers in Veterans Exposed to Open Burn Pits
Background: The VA and DoD estimate that 3.5 million Veterans and Service Members were exposed to open burn pits used for waste disposal during military deployments to countries such as Kuwait, Afghanistan, and Iraq since 1990.
- Trial name
- NCT06305091
- Testing
- Health survey for physical and mental health comorbidities, epigenetic marker and heavy metals in blood and urine samples
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Central Arkansas Veterans Healthcare System