Clinical trials: Burn Surgery
Reconstruction of First Web Space
Reconstruction of First Web Space After Trauma and Burn
assess and compare the functional and aesthetic outcomes of different surgical techniques used for reconstruction of post-traumatic and post-burn first web space obliteration.
- Trial name
- NCT07762404
- Testing
- Reconstruction of post burn first web space obliteration in hand, First web space Reconstruction, Reconstruction of first web space
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sohag University
Burns
Oxycodone (10, 20 mg) in a Postoperative Dressing
The study mainly focuses on pain management using 10- or 20mg oxycodone burn wound dressing at Poznan University of Medical Sciences.
- Trial name
- NCT06142591
- Testing
- Oxycodone 10mg, Oxycodone 20mg
- Volunteers
- 20 people
- Sponsor
- Poznan University of Medical Sciences
Burn, Reconstructive Surgical Procedure
Evaluation Perioperative Nutrition on Donor Site Healing in Patients Undergoing Reconstructive Burn Surg
The investigators hope to learn if taking a nutrition drink for a short time after surgery for an elective reconstructive burn injury improves donor site healing, muscle mass and scar maturation time (the point at which the…
- Trial name
- NCT00539097
- Testing
- Juven (Ross Products) protein supplement
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Shriners Hospitals for Children
Donor Site Complication
An Investigation to Evaluate a New Donor Site Dressing in Surgical Burn Patients
The investigator will identify the test donor site and test location will be considered on the upper anterior thighs as being the most suitable if available. Circumferential donors will be considered acceptable as well.
- Trial name
- NCT01670201
- Testing
- Mepilex Transfer Ag
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Molnlycke Health Care AB
Burn, Surgery
A Randomized, Controlled Trial of the Effectiveness of Perioperative Antibiotics for Reduction of Burn Wound Bacterial Concentration Following Grafting
The purpose of this study if to evaluate the effectiveness of prophylactic antibiotics given during surgery in reducing the concentration of bacteria in a burn wound after surgery.
- Conditions
- Burn, Surgery, Infection Wound
- Trial name
- NCT04516148
- Testing
- Cefazolin, Clindamycin
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Medstar Health Research Institute
Blood Loss, Surgical
Phenylephrine Tumescence for Hemostasis in Surgery for Burn Injury
The standard of care for treatment of burn injury is to inject a solution of epinephrine under the skin of the injured site in order to reduce blood loss during skin grafting.
- Trial name
- NCT01731444
- Testing
- Phenylephrine
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of Manitoba
Burn
Multicenter Benchmarking of Functional and Psychosocial Outcomes of Pediatric Burn Survivors
The purpose of this study is to establish an expected recovery trajectory (recovery model) in terms of physical and psychological function of the pediatric burn patient.
- Trial name
- NCT00239668
- Where
- 4 sites in United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Diabetic Foot Ulcer, Venous Leg Ulcer
PLASOMA Ultimate Safety & Efficacy Study
The purpose of the PULSE study are the followingL A.To perform post market clinical follow up (PMCF) on safety and efficacy: 1. Safety: To confirm transient short-terms side effects and verify long-term/outstanding risks. 2.
- Conditions
- Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer, Burn Wound
- Trial name
- PULSE (NCT04828304)
- Testing
- PLASOMA
- Where
- 6 sites in Netherlands
- Volunteers
- 101 people
- Sponsor
- Plasmacure
Burn Surgery
Comparison of AWBAT™-D and MEPILEX® AG for Treatment of Donor Sites in Burn Surgery
The purpose of this study is to examine AWBAT™-D compared to Mepilex® Ag for the treatment of donor sites in burn surgery.
- Trial name
- NCT00974597
- Testing
- AWBAT™-D and Mepilex® Ag dressings
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aubrey Inc.
Anesthesia, Burned
Development of pk/pd Model of Propofol in Patients With Severe Burns
Burn injuries are a prevalent problem. Actually, in Chile the Ministry of Health has recorded 6435 hospital burns and has reported 569 deaths from this cause.
- Conditions
- Anesthesia, Burned, Operative Wound
- Trial name
- HUAPQ (NCT03704285)
- Testing
- Propofol, BIS
- Where
- Chile
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Victor Contreras, MSN
Burn of Face, Head and/or Neck, Peeling
Histological Skin Changes of Different Peeling Agents in Surgically Subcutaneous Undermined Skin
The purpose of this study is to examine the histological skin changes induced by different peeling agents (Trichloroacetic acid 25% and 40% and phenol/croton oil) in subcutaneous undermined facial skin flaps.
- Trial name
- NCT02848209
- Testing
- TCA 20% Peeling, Phenol/croton oil Peeling, TCA 40% Peeling
- Where
- Spain
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Burns
Timing of Surgery And Outcome in Burn Patients ( EARLYBURN )
The prognostic of burn patients has improved over the last decades. Early excision of full thickness burns is thought to be one of the key factors which have led to prognostic improvement.
- Trial name
- EARLYBURN (NCT02940171)
- Testing
- Early Excision of full thickness burn, Late Excision of full thickness burn
- Where
- France
- Volunteers
- 470 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Burns, Contracture Scar
Autologous Point-of-Care Adipose Therapy: Delayed Injury/Scar
The goal of this study is to explore if an adipose-based therapeutic strategy can treat contracted scars secondary to soft-tissue burn wounds in injured individuals, especially those with severe burns or soft-tissue loss.
- Conditions
- Burns, Contracture Scar, Surgical Injury
- Trial name
- NCT06857435
- Testing
- Full Thickness Skin Graft (FTSG), Base of wound fat graft with Split Thickness Skin Graft (STSG) Reconstruction (Autologous Layered Composite Grafting).
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh
Critical Illness, Burns
Effect of Active Drain Line Clearance on Catheter-Associated Bacteriuria
Catheter-associated urinary tract infections (CAUTI) are the most common nosocomial infections in critically ill patients and are responsible for high morbidity rates, increased hospital stays and associated costs.
- Conditions
- Critical Illness, Burns, Surgery, Urinary Tract Infections
- Trial name
- CAB (NCT03816384)
- Testing
- Standard of Care, DLC Group, DLCS Group
- Sponsor
- Potrero Medical
Burn Out Syndrome
Level of Burn Out of Surgical Residents Working in All Hospitals of Lahore
The term burnout was coined by psychologist Herbert Freudenberger in 1974 in an article entitled "Staff Burnout" in which he discussed job dissatisfaction precipitated by work-related stress.
- Trial name
- NCT02206139
- Where
- 2 sites in Pakistan
- Volunteers
- 150 people
- Sponsor
- Services Hospital, Lahore
Fuchs Endothelial Corneal Dystrophy, Pseudophakic Bullous Keratopathy
The Postoperative Head Position as a Predictor of the Surgical Outcome After DMEK
This study aims to investigate the influence of postoperative head position on clinical outcomes after DMEK via a wearable sensor.
- Conditions
- Fuchs Endothelial Corneal Dystrophy, Pseudophakic Bullous Keratopathy, Chemical Burn of Cornea, Posterior Polymorphous Corneal Dystrophy
- Trial name
- NCT04387331
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Peter Wiedemann
Chimerism, Blood Transfusion
Transfusion-Associated Microchimerism in Previously Injured Individuals Who Received a Blood Transfusion
Blood transfusions are frequently necessary in situations in which there is a large amount of blood loss. In some individuals who receive a blood transfusion, white blood cells from the donor's blood may remain in the body for…
- Conditions
- Chimerism, Blood Transfusion, Wounds and Injuries
- Trial name
- NCT00441779
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Sepsis, Burn Injury
Surgical Critical Care Initiative (SC2i) Tissue and Data Acquisition Protocol (TDAP) in Burn Patients Improving the Robustness and Generalizability of Post-burn Sepsis Prediction With the Post-Burn Sepsis Digital Twin. Group 1
This study is following adult patients with serious burn injuries to better understand how their bodies respond to treatment and recovery.
- Conditions
- Sepsis, Burn Injury, Wound Healing, Critical Illness
- Trial name
- NCT07249762
- Testing
- Observational Cohort (No Intervention)
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Surgical Wound, Burns
A Prospective Study Using SupraSDRM® in Promoting Healing and Reducing the Time to Grafting of Full-thickness Wounds
This is a prospective, randomized, controlled, multi-center clinical study comparing SupraSDRM® to standard of care wound dressing, BTM, in the treatment of full-thickness wounds deemed not immediately suitable for definitive…
- Conditions
- Surgical Wound, Burns, Trauma Injury
- Trial name
- NCT06503406
- Testing
- SupraSDRM®, NovoSorb® BTM
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- The Metis Foundation
Smoke Inhalation
Electronic Cigarette and Surgery (ECigarSurg)
Since decades, literature has shown that smoking has negative effect on postoperative outcome. Recent systematic review and meta-analysis on clinical impact of smoking and smoking cessation showed that postoperative healing…
- Trial name
- ECigarSurg (NCT03594643)
- Where
- France
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes