Clinical trials: Burning
Pain
Assessment of Peripheral GABA Receptors for Local Pain Relief
The effect of peripheral GABAA receptor activation on pain and sensitivity in healthy human subjects has never been investigated.
- Trial name
- NCT02928328
- Testing
- GABA oral solution, Intramuscular GABA, Pain modulation
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Burning Mouth Syndrome
Treatment of Burning Mouth Syndrome With Integration of Traditional Chinese Medicine and Western Medicine
This study is an open-label randomized controlled trial of the efficacy of the integration of Traditional Chinese medicine (TCM) and western medicine based on TCM syndrome differentiation.
- Trial name
- NCT04189367
- Testing
- Traditional Chinese Medicine, Western medicine
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Mucositis, Dry Mouth
Effect of Fluoride Varnish and CPP-ACP on Oral and Salivary Symptoms During Chemotherapy
The purpose of this study was to investigate the effect of Fluoride varnish and Casein Phospho-Peptide Amorphous Calcium Phosphate (CPP-ACP) containing paste on oral symptoms and salivary characteristics in patients under…
- Conditions
- Mucositis, Dry Mouth, Infection
- Trial name
- NCT01737307
- Testing
- Fluoride varnish, Oral Hygiene, CPP-ACP
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Azad University of Medical Sciences
Burning Mouth Syndrome
Study Evaluating the Laser Diode Effect Burning Mouth Syndrome
The aim of this study was to report the effect of laser diode on the treatment of burning mouth syndrome (BMS) Patients were randomly allocated to two different groups: the first one (group A) underwent Laser diode whereas the…
- Trial name
- laser (NCT02757612)
- Testing
- laser diode
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Burning Mouth Syndrome, Stomatodynia
Topical Amitriptyline 1% Gel for the Treatment of Burning Mouth Syndrome
Burning mouth syndrome (BMS) is a chronic oral pain condition that causes a persistent burning or stinging sensation in the mouth, often without visible changes in the tissues.
- Trial name
- TOP-AMI → TOPi (NCT07214181)
- Testing
- Topical amitriptyline 1% gel
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad de Murcia
Neuropathic Pain, Pain
Effects of Venlafaxine on Chronic Neuropathic Pain Following Spinal Cord Injury
The purpose of this study is to evaluate the pain-relieving effects of venlafaxine hydrochloride (Effexor) in chronic neuropathic (burning, shock-like, electric) pain after spinal cord injury (SCI).
- Conditions
- Neuropathic Pain, Pain, Spinal Cord Injuries
- Trial name
- NCT00167856
- Testing
- Venalafaxine hydrochloride
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- US Department of Veterans Affairs
Burning
Dexmedetomidine for Morphine Consumption Reduction (DEXDOR)
The new progresses relative to sedation-analgesia for resuscitation unit lead to perform a light and cooperative sedation as soon as possible in order to decrease the period of mechanical ventilation.
- Trial name
- DEXDOR (NCT02904460)
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Burning Mouth Syndrome
The Role of Xerostomia in Burning Mouth Syndrome: Case - Control Study
Objectives: to evaluate xerostomia and salivary flow in patients with burning mouth syndrome (BMS) treated with amitriptyline before and after the use of antixerostomic topical medication.
- Trial name
- BMS (NCT01754740)
- Testing
- Uréia
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- University of Sao Paulo General Hospital
Burning Mouth Syndrome, Taste Disorder
Burning Mouth Disorder (BMD) - A Neuropathic Pain Disorder
Oral burning can have a multitude of reasons. Recent neurophysiologic study results suggest that a primary burning mouth disorder (BMD) may be a peripheral and/or a central neuropathic disorder.
- Conditions
- Burning Mouth Syndrome, Taste Disorder, Orofacial Pain
- Trial name
- NCT00504387
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- Markus R. Fussnegger
Atrophic Glossitis, Burning Mouth Syndrome
HLA-DRB1 and HLA-DQB1 Genotyping for Autoantibody-positive and -Negative Patients With Atrophic Glossitis or Burning Mouth Syndrome
Patients with atrophic glossitis (AG) or burning mouth syndrome (BMS) are frequently encountered in the oral mucosal disease clinic.
- Trial name
- NCT01931293
- Testing
- Supplementation of vitamin B complex, C, B12, folic acid, Iron and Zinic
- Where
- Taiwan
- Volunteers
- 750 people
- Sponsor
- National Taiwan University Hospital
Painful Diabetic Neuropathies
Safety and Efficacy Study for the Treatment of Painful Diabetic Neuropathy
The purpose of this study is to determine if Engensis (VM202) is safe and effective in treating painful diabetic neuropathy.
- Trial name
- NCT01475786
- Testing
- Low Dose: 16 mg Engensis (VM202), High Dose: 32 mg Engensis (VM202)
- Where
- 17 sites in United States, South Korea
- Volunteers
- 104 people
- Sponsor
- Helixmith Co., Ltd.
Pain, Urinary Tract Infections
Evaluate the Safety and Efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg vs. Placebo
This study will evaluate the safety and efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg as a short term analgesic treatment for the primary symptoms of pain or burning when passing urine associated with…
- Trial name
- NCT01064024
- Testing
- Phenazopyridine Hydrochloride
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- Amneal Pharmaceuticals, LLC
Painful Diabetic Neuropathy, Diabetic Neuropathy, Painful
Phase 3 Gene Therapy for Painful Diabetic Neuropathy
The purpose of this study is to determine the safety and efficacy of bilateral intramuscular injections of VM202 versus placebo in the treatment of painful diabetic peripheral neuropathy.
- Trial name
- NCT02427464
- Testing
- Engensis (VM202)
- Where
- 25 sites in United States
- Volunteers
- 507 people
- Sponsor
- Helixmith Co., Ltd.
Burning Mouth Syndrome
Botulinum Toxin in Burning Mouth Syndrome
The effect of botulinum neurotoxin type A intradermal injection in will be evaluated in 4 patients with clinical diagnosis of burning mouth syndrome involving the anterior two-thirds of the tongue and the lower lip for at least 6…
- Trial name
- NCT02964728
- Testing
- Botulinum Neurotoxin Type A, Normal saline
- Volunteers
- 6 people
- Sponsor
- Presidio Ospedaliero Garibaldi-Centro
Burning Pain, Impaired Balance
Feasibility Study of New Method of Diagnostic and Prediction of Painful CIPN
This clinical trial studies how well Diode laser fiber type Selective Stimulator (DLss) works in predicting pain development in patients with ovarian cancer who are receiving chemotherapy.
- Conditions
- Burning Pain, Impaired Balance, Malignant Ovarian Neoplasm, Numbness
- Trial name
- NCT03206216
- Testing
- Diode Laser fiber type Selective Stimulator (DLss)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Stanford University
Genitourinary Syndrome of Menopause (GSM), Vaginal Dryness
To Assess Signs and Symptoms in Women Affected by GSM After One Cycle of Pixel CO2-Alma Fractionated Laser
Genitourinary syndrome of menopause (GSM) occurs in approximately 50% of menopausal women but is both underrecognized and undertreated despite numerous treatment options.
- Conditions
- Genitourinary Syndrome of Menopause (GSM), Vaginal Dryness, Burning, Pain
- Trial name
- NCT05156502
- Testing
- Fractionated Laser (Pixel CO2-Alma), Fractionated Laser (Pixel CO.2-Alma)
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dr. Filippo Murina
Burning Mouth Syndrome
Comparison of Vortioxetine Versus Other Antidepressants With Pregabalin Augmentation in Burning Mouth Syndrome
Background: The treatment of Burning Mouth Syndrome (BMS) presents a challenge in tailoring appropriate medication for individual patients.
- Trial name
- NCT06025474
- Testing
- Vortioxetine 20Mg Tab, Paroxetine 20 Mg Oral Tablet, Sertraline 50 MG
- Where
- Italy
- Volunteers
- 203 people
- Sponsor
- Federico II University
Burning Mouth Syndrome
A Study of the Association of Sleep Dysfunction and Burning Mouth Syndrome
This is a case control study of the association between burning mouth syndrome and sleep dysfunction. Cases will comprise of patients diagnosed with burning mouth syndrome at the UCSF oral medicine clinic.
- Trial name
- NCT00862576
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of California, San Francisco
Burning Mouth Syndrome
Inflammatory Markers in Saliva of Patients With Burning Mouth Syndrome
Burning Mouth Syndrome (BMS) is a chronic pain disorder that presents with inflammation and burning sensation in the oral cavity without visible lesions.
- Trial name
- burningmouth (NCT06217731)
- Testing
- Laser+clonazepam, Laser, Clonazepam
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad de Murcia
Oral Lichen Planus, Recurrent Aphthous Stomatitis
Improving Prescribing Quality for Oral Mucosal Disorders Using a Pharmacist-Led Model
This study aims to improve how oral mucosal disorders-such as oral lichen planus, recurrent aphthous stomatitis, burning mouth syndrome, herpes viral infection and oral candidiasis-are treated in dental settings.
- Conditions
- Oral Lichen Planus, Recurrent Aphthous Stomatitis, Burning Mouth Syndrome, Oral Candidiasis
- Trial name
- NCT07721090
- Testing
- Pharmacist-Led Prescribing Optimization and Patient Counselling
- Volunteers
- 336 people
- Sponsor
- University of Fujairah