Clinical trials: Burning
Burning Mouth Syndrome
The Efficacy of N-acetyl-cysteine in the Treatment of Burning Mouth Syndrome
The purpose of this study was to examine the efficacy of N-acetyl cysteine in the treatment of burning mouth syndrome. A control group of patients with burning mouth syndrome will receive a placebo.
- Trial name
- NCT05309070
- Testing
- N-acetyl cysteine
- Where
- Croatia
- Volunteers
- 80 people
- Sponsor
- University of Zagreb
Burning Mouth Syndrome
Comparison Between Two Treatments for Burning Mouth
Introduction: The management of patients with chronic burning mouth is a challenge in clinical dentistry. Objective: To compare the effect of Low Level Laser Therapy (LLLT) and Transcutaneous Electrical Nerve Stimulation (TENS)…
- Trial name
- NCT05816200
- Testing
- Low-Level Light Therapy, Transcutaneous Electric Nerve Stimulation
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Genitourinary Syndrome of Menopause (GSM), Vaginal Dryness
To Assess Signs and Symptoms in Women Affected by GSM After One Cycle of Pixel CO2-Alma Fractionated Laser
Genitourinary syndrome of menopause (GSM) occurs in approximately 50% of menopausal women but is both underrecognized and undertreated despite numerous treatment options.
- Conditions
- Genitourinary Syndrome of Menopause (GSM), Vaginal Dryness, Burning, Pain
- Trial name
- NCT05156502
- Testing
- Fractionated Laser (Pixel CO2-Alma), Fractionated Laser (Pixel CO.2-Alma)
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dr. Filippo Murina
Chronic Pain
Clinical Trials With a Local Anesthetic Lozenge for the Treatment of Chronic Oral Pain
The aim of the project is to do a fase two trial, where the effect of a local anesthetic lozenge will be tested in regard to oral pain, dryness of the mouth, irregularity of taste as well as investigate a potential…
- Trial name
- NCT01584947
- Testing
- Bupivacaine
- Where
- Denmark
- Volunteers
- 31 people
- Sponsor
- Hvidovre University Hospital
Burning Mouth Syndrome
A Study of the Association of Sleep Dysfunction and Burning Mouth Syndrome
This is a case control study of the association between burning mouth syndrome and sleep dysfunction. Cases will comprise of patients diagnosed with burning mouth syndrome at the UCSF oral medicine clinic.
- Trial name
- NCT00862576
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of California, San Francisco
Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain
Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN)
Peripheral neuropathy is a disorder caused by damage to the peripheral nerves. Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of certain chemotherapy drugs, such as platinum-based compounds, taxanes…
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain, CIPN - Chemotherapy-Induced Peripheral Neuropathy, Peripheral Neuropathic Pain
- Trial name
- NCT07072468
- Testing
- VMD-3866 Gel
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- VM Therapeutics LLC
Pain, Burning
Ketamine Continuous Infusion on Opioid Consumption and Pain Management in Severe Burned Patients
The purpose of this study is to evaluate the efficacy of ketamine in continuous infusion in the control of pain intensity, the impact on the consumption of opioids and observe the side effect profile in patients suffering from…
- Trial name
- ccimb (NCT02860117)
- Testing
- Ketamine continuous infusion
- Where
- Brazil
- Sponsor
- University of Sao Paulo General Hospital
Exercise
A Study to See if an Energy Drink With Caffeine and Green Tea Increases Fat Burning When Exercising
The goal of this study is to evaluate the influence of consuming a drink containing a combination of caffeine and green tea extracts on fat oxidation responses at rest, during and after a period of endurance type exercise.
- Trial name
- NCT07434752
- Testing
- Active (Green tea and caffeine)
- Where
- Australia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Burning Mouth Syndrome
Burning Mouth Syndrome: Symptoms and Management
This research study aims to evaluate how an oral cooling spray, currently a commercial dietary supplement, impacts symptoms associated with burning mouth syndrome (BMS).
- Trial name
- NCT07016555
- Testing
- Oral cooling spray
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Massachusetts, Amherst
Dry Eyes, Allergic Conjunctivitis
Evaluating Patients With Eye Allergies and Determining if There Are Also Dry Eyes
Evaluating the percentage of patients that suffer from eye allergies and determining whether they also have dry eyes.
- Trial name
- NCT01679015
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Schwartz Laser Eye Center
Lung Function, Heart Rate Variability
Effects of Exposure to Biomass-burning Air Pollution on Lung Function, Heart Rate Variability and Inflammatory Markers in Sugarcane Workers
Introduction: Non-mechanized sugar cane harvesting preceded by burning, an important and prevalent professional activity of agribusiness segment of the Brazilian economy, exposes workers and people of neighboring towns to high…
- Conditions
- Lung Function, Heart Rate Variability, Oxidative Stress, Systemic Inflammatory Response
- Trial name
- NCT01371188
- Where
- Brazil
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- InCor Heart Institute
Uncomplicated Urinary Tract Infections
Safety and Efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg as an Analgesic for Short-Term Treatment in Female Subjects Suffering From Moderate-to-Severe Pain and Burning Upon Urination Associated With Uncomplicated Urinary Tract Infections (uUTI)
The primary objective is to evaluate the safety and efficacy of Phenazopyridine HCl Tablets, USP 200 mg as a short term analgesic treatment of pain upon urination associated with Uncomplicated Urinary Tract Infections (uUTI).
- Trial name
- NCT01650051
- Testing
- Phenazopyridine Hydrochloride Tables, USP 200 mg
- Where
- United States
- Volunteers
- 424 people
- Sponsor
- Amneal Pharmaceuticals, LLC
Pain
The Effect of Ablation of Epidermal Nerve Fibers Using Capsaicin Cream
This is a study of epidermal (the outer most layer) nerve fibers (ENFs) in the skin of the body; counts of which are used to determine a disease of nerves called "small nerve fiber neuropathy." Capsaicin is approved by the Food…
- Trial name
- NCT01883102
- Testing
- Capsaicin 0.1%
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Burning Mouth Syndrome, Taste Disorder
Burning Mouth Disorder (BMD) - A Neuropathic Pain Disorder
Oral burning can have a multitude of reasons. Recent neurophysiologic study results suggest that a primary burning mouth disorder (BMD) may be a peripheral and/or a central neuropathic disorder.
- Conditions
- Burning Mouth Syndrome, Taste Disorder, Orofacial Pain
- Trial name
- NCT00504387
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- Markus R. Fussnegger
Pain
Topical Local Anaesthesia and Cooling During Capsaicin 8% Patch Application
Aim of the study is to demonstrate superiority of a continuous cooling of the skin over topical EMLA or placebo in reducing the burning pain during the application of capsaicin 8% patch ("Qutenza").
- Trial name
- LACCA (NCT01523951)
- Where
- Austria
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Contact Dermatitis
Effect of Tetrix on Alleviation of Burning,Itching Associated With Lesions of Contact Dermatitis
To determine if Tetrix Cream, when applied to the skin lesions on patients with contact dermatitis, improves the symptoms of burning and itching.
- Trial name
- NCT00646867
- Testing
- Tetrix
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Coria Laboratories, Ltd.
Primary Burning Mouth Syndrome (BMS)
Theravex® for Burning Mouth Syndrome
In this randomized, double-blind, placebo-controlled trial, 116 adults with primary BMS were assigned (1:1) to receive THERAVEX® Total Oral Care Plus or placebo for 8 weeks.
- Trial name
- NCT07564843
- Testing
- THERAVEX® Total Oral Care Plus
- Where
- Egypt
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Biointelligent Technology Systems SL
Pain, Diabetic Neuropathies
A Research Study of V3381 for the Treatment of Diabetic Peripheral Neuropathic Pain
The objective of this study is to investigate the safety and efficacy of an investigational drug, V3381, for the treatment of diabetic peripheral neuropathic (DPN) pain (pain in one's feet and legs, or even in one's hands and…
- Trial name
- NCT00375960
- Testing
- V3381
- Where
- 6 sites in United States, Canada
- Volunteers
- 50 people
- Sponsor
- Vernalis (R&D) Ltd
Candle Burning, Cooking
Acute Health Effects Due to Ultrafine Particles From Candles and Cooking
People spend up to 90% of their life indoor, and the way we live and behave in our homes has substantial effects on our health and well-being.
- Conditions
- Candle Burning, Cooking, Lung Function Decreased, DNA Damage
- Trial name
- Ultrafine (NCT04315740)
- Testing
- Particles from candles, Particles from cooking, Clean Air
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Oral Submucous Fibrosis
Alternating Triamcinolone and Platelet-Rich Plasma Therapy for Oral Submucous Fibrosis
Oral Submucous Fibrosis (OSF) is a chronic, progressive, potentially malignant disorder characterized by mucosal stiffness, trismus, and burning sensation.
- Trial name
- RegenOSF (NCT07277998)
- Testing
- Platelet-Rich Plasma (PRP) Injections, Triamcinolone Acetonide
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Karachi Medical and Dental College