Clinical trials: Bypass Graft Occlusion
Coronary Artery Disease (CAD), Coronary Artery Bypass Graft (CABG)
Effects of a Recovery-Promoting Program in Patients Undergoing CABG Surgery
Patients undergoing coronary artery bypass graft (CABG) surgery often experience physical limitations, psychological stress, and challenges during recovery after hospital discharge.
- Conditions
- Coronary Artery Disease (CAD), Coronary Artery Bypass Graft (CABG), Postoperative Recovery
- Trial name
- NCT07392021
- Testing
- Recovery Promotion Program for CABG patients, Standard Postoperative CABG Care
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Coronary Artery Occlusive Disease
The Effect of 6% Hydroxyethyl Starch 130/0.4 on Blood Loss and Coagulation in Patients Medicated With Antiplatelet Agents Prior to Off-Pump Coronary Bypass Graft Surgery
HES 130/0.4 significantly solution will not affect on coagulation and blood loss in patients medicated with antiplatelet agents prior to off-pump coronary bypass surgery (OPCAB).
- Trial name
- NCT01051206
- Testing
- 6% hydroxyethyl Stach 130/0.4
- Where
- South Korea
- Volunteers
- 106 people
- Sponsor
- Yonsei University
Peripheral Arterial Disease
Endothelial Function in Lower Extremity Bypass Grafts
This study will determine whether or not saphenous vein [arterial] bypass grafts in the leg relax in response to increases in blood flow.
- Trial name
- NCT00759707
- Testing
- L-N^G monomethyl arginine (L-NMMA)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Brigham and Women's Hospital
Angina, Coronary Artery Disease
Exercise-training Before Coronary Artery Bypass Graft (CABG)
The aim is to evaluate the effect of exercise training upon endothelial function in the mammary artery of patients who are scheduled for CABG, as well as study the functional properties of single cells isolated from a small…
- Trial name
- NCT00218985
- Testing
- Exercise training
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Cardiovascular Disease, Coronary Artery Disease
Radial Artery Versus Saphenous Vein Grafts in Coronary Artery Bypass Surgery
VA patients with coronary artery disease and who have agreed to undergo coronary artery bypass graft surgery would be randomized to receive either radial artery or saphenous vein to the study vessel.
- Trial name
- NCT00054847
- Testing
- saphenous vein graft, radial artery graft
- Where
- 11 sites in United States
- Volunteers
- 733 people
- Sponsor
- US Department of Veterans Affairs
Coronary Artery Disease, Physical Activity
Preoperative Excercise Training for Patients Undergoing Coronary Artery Bypass Graft Surgery
Patients (pts) with stable coronary artery disease (CAD) requiring coronary artery bypass graft surgery (CABG) may be physically inactive during the waiting period to avoid further risks.
- Conditions
- Coronary Artery Disease, Physical Activity, Coronary Artery Bypass Graft Surgery
- Trial name
- NCT04111744
- Testing
- Preoperative Exercise Training, Optimal medical therapy
- Where
- Germany
- Volunteers
- 203 people
- Sponsor
- Kerckhoff Klinik
Aortic Valve Stenosis, Mitral Valve Disease
Quality of Life After Cardiac Surgery
During the last twenty years heart surgery has become safer and the number of patients having heart surgery has increased with more frail patients being offered increasingly complex surgery.
- Conditions
- Aortic Valve Stenosis, Mitral Valve Disease, Tricuspid Valve Disease, Aorta Disease
- Trial name
- QUACS (NCT04231461)
- Testing
- Cardiac Surgery
- Where
- United Kingdom
- Volunteers
- 2,925 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Coronary Bypass Graft Occlusion
Diagnostic and Prognostic Value of Cardiac Biomarkers for Early Coronary Bypass Occlusion in Patients Undergoing Coronary Revascularization
This study is to evaluate the correlation between hs-cTn level as cardiac biomarker for ischemia and early graft occlusion as assessed by CCT in patients undergoing coronary bypass surgery.
- Trial name
- NCT04595630
- Testing
- data collection from the hospital records
- Where
- 3 sites in Croatia, Poland and 1 more
- Volunteers
- 480 people
- Sponsor
- University Hospital, Basel, Switzerland
Coronary Artery Disease
Hybrid Coronary Revascularization Trial
The purpose of the study is to learn which treatment option is better for patients who have multi-vessel coronary artery disease (blockages in more than one vessel supplying blood to the heart muscle).
- Trial name
- NCT03089398
- Testing
- Hybrid Coronary Revascularization (isolated LIMA-LAD), Hybrid Coronary Revascularization (PCI), Percutaneous Coronary Intervention
- Where
- 46 sites in United States, Canada
- Volunteers
- 200 people
- Sponsor
- Emilia Bagiella
Coronary Artery Disease, Systemic Inflammation
MIECC vs Conventional Cardiopulmonary Bypass and Systemic Inflammation in CABG
This prospective observational study evaluates the effects of minimally invasive extracorporeal circulation (MIECC) and conventional cardiopulmonary bypass on systemic inflammatory response in patients undergoing coronary artery…
- Trial name
- MIECC-CABG (NCT07823400)
- Testing
- Minimally Invasive Extracorporeal Circulation, Conventional Cardiopulmonary Bypass
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Coronary Artery Disease, Postoperative Complications
Intraoperative Targeted Versus Liberal Blood Pressure Management in Patients Undergoing Off-pump Coronary Artery Bypass Grafting
The goal of this clinical trial is to learn whether two approaches to anesthesia and blood pressure management can improve care for adults having off-pump coronary artery bypass grafting (OPCAB).
- Trial name
- NCT07787364
- Testing
- Targeted Blood Pressure Management, Liberal Blood Pressure Management, Remimazolam
- Volunteers
- 416 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Coronary Artery Disease
Home-Based Versus Center-Based Cardiac Rehabilitation After CABG Surgery
This randomized controlled trial was designed to compare the efficacy of a 12-week home-based telerehabilitation (HBTCR) program against traditional center-based cardiac rehabilitation (CBCR) and usual care in patients who have…
- Trial name
- NCT07243444
- Testing
- Structured Exercise Program, Standard Health Education
- Where
- China
- Volunteers
- 110 people
- Sponsor
- The First Hospital of Hebei Medical University
Coronary Artery Disease, Myocardial Ischemia
The eSVS® Mesh Post-Marketing Trial
The purpose of this study is to evaluate patency rates of the eSVS Mesh Saphenous Vein Graph (SVG) and control SVG at six and twenty-four months via coronary angiography and analyses of Duplex Sonography Results and coronary…
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Coronary Disease, Heart Diseases
- Trial name
- NCT01520311
- Testing
- eSVS Mesh
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- Kips Bay Medical, Inc.
Coronary Artery Bypass Grafting or Heart Valve Surgery Via Median Sternotomy
Transversus Thoracis Muscle Plane Block Plus Rectus Sheath Block in the Perioperative Pain Management of Cardiac Surgery
An emerging regional block technique, transverse thoracic muscle block covers the T2-T6 intercostal nerves and can effectively relieve perioperative pain during median sternotomy.
- Trial name
- NCT04838132
- Testing
- Bilateral transversus thoracis muscle plane and rectus sheath block with ropivacaine, Bilateral transversus thoracis muscle plane and rectus sheath puncture with saline
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Guangzhou First People's Hospital
Carotid Stenosis
Platelet Inhibition and Transcranial Doppler (TCD)-Detected Microemboli During and After Carotid Artery Stenting (CAS) in Asymptomatic Patients Prior to Cardiac Surgery
As with coronary artery stenting, activation and embolisation of platelets occurs with carotid artery stenting (CAS). Based on promising data on the use of clopidogrel plus aspirin in coronary stenting this dual antiplatelet…
- Trial name
- IMPACT (NCT01146301)
- Testing
- Clopidogrel
- Where
- Netherlands
- Sponsor
- R&D Cardiologie
Coronary Stenosis, Coronary Artery Disease
Percutaneous Coronary Intervention (PCI) With Drug-Eluting Stents (DES) Versus Coronary Artery Bypass Graft (CABG) for Patients With Significant Left Main Stenosis
Recent technical advances in percutaneous coronary interventions have made it possible to approach patients with coronary lesions formerly considered to be classical candidates for bypass surgery, e.g.
- Trial name
- NCT00176397
- Testing
- Percutaneous coronary intervention (left main)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University of Leipzig
CABG, Physiological Parameter
The Effect of Virtual Reality and Eye Mask During Dressing After CABG Surgery
This study aims to evaluate the effects of virtual reality (VR) and eye mask (EM) applications on pain, anxiety, and physiological parameters during dressing after Coronary Artery Bypass Graft (CABG) surgery.
- Conditions
- CABG, Physiological Parameter, Postoperative Pain, Postoperative Anxiety
- Trial name
- CABG (NCT07039812)
- Testing
- Virtual Reality Headset, Eye Mask
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul University - Cerrahpasa
Coronary Artery Bypass Grafting, Remimazolam
Remimazolam for Postoperative Atrial Fibrillation
Atrial fibrillation (AF) is the most common cardiac severe arrhythmia globally and is associated with an increased risk of mortality and morbidity, with a loss of 6.0 million disability-adjusted life-years worldwide in 2017…
- Trial name
- RePAF (NCT05891145)
- Testing
- Remimazolam, midazolam
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Yangzhou University
Coronary Artery Disease, Multivessel Coronary Artery Disease
Robotically-assisted Minimally-invasive Direct Coronary Artery Bypass With Stenting, Randomized Against Coronary Artery Bypass Graft Surgery
The study objective is to compare standard CABG to a hybrid revascularization strategy (RA-MIDCAB + PCI) in patients who have multi-vessel CAD and an indication for surgery, but who have a slightly higher risk of post-operative…
- Trial name
- ROBOT RCT (NCT06378775)
- Testing
- Coronary Artery Bypass Graft, Robotically-assisted minimally-invasive direct coronary artery bypass, Percutaneous Coronary Intervention
- Volunteers
- 80 people
- Sponsor
- Cardiology Research UBC
Peripheral Artery Disease
Vorapaxar and Lower Extremity Bypass Grafts
There are no medical therapies indicated for reduction of limb ischemic events. Studies of dual-antiplatelet therapy with aspirin and clopidogrel versus aspirin alone (CASPAR) as well as studies of systemic anticoagulation (WAVE)…
- Trial name
- NCT02975583
- Testing
- Vorapaxar
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University