Clinical trials: C Reactive Protein
Asthma, Inflammation
Vascular Implications of a Naturally Occurring Asthma Exacerbation
Although asthma is a disease of the airways, research is now showing that asthmatics are more likely to develop cardiovascular disease (CVD) compared to non-asthmatics.
- Conditions
- Asthma, Inflammation, Cardiovascular Risk Factor
- Trial name
- NCT03679299
- Testing
- Observational - No intervention
- Where
- 2 sites in Canada
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Periodontitis
Impact of C-reactive Protein on Non Surgical Periodontal Treatment
In light of the controversy that are already approved but that however still exists regarding the efficacy and influence the management of Periodontitis, the aim of this study was to evaluates, at 12-months follow-up, the…
- Trial name
- NCT05836298
- Testing
- Non-surgical periodontal treatment
- Where
- Italy
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Catania
Stroke, National Institutes of Health Stroke Scale
Multivariate Analysis of Serum High Sensitivity C-Reactive Protein in Patients With Acute Phase Stroke
Stroke is one of main causes of death and impairment worldwide. Objective of this study is to analyze serum High Sensitivity C-Reactive Protein in acute phase stroke in patients attended at Petróleos Mexicanos Hospital Central…
- Conditions
- Stroke, National Institutes of Health Stroke Scale, Serum High Sensitivity C-Reactive Protein
- Trial name
- MAASP (NCT02171858)
- Where
- Mexico
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hospital Central Sur de Alta Especialidad
Asthma
C-Reactive Protein as a Predictor for Airway Hyper-Responsiveness
Background: Increased serum high sensitivity C-reactive protein (hs-CRP) has been associated with airway inflammation in asthma and may serve as a surrogate marker for the presence of airway hyper-responsiveness (AHR) in this…
- Trial name
- NCT01002144
- Testing
- blood sampling
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Chronic Periodontitis
Role of Leukotriene Receptor Antagonists in Treatment of Chronic Periodontitis
The adjunctive use of Leukotriene Receptor Antagonist (Montelukast) along with scaling and root planing in patients with chronic periodontitis leads to host inflammatory response modulation and decrease in serum C reactive…
- Trial name
- NCT02014532
- Testing
- Montelukast
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
COPD Patients, Healthy Subjects
Pulmonary Arterial Pressure Response During Exercise
Background: The extent of increase in systolic pulmonary arterial pressure (PAPs) during exercise in patients with COPD is unpredictable from lung function data.
- Conditions
- COPD Patients, Healthy Subjects, Semi-supine Echo (SSE), Flow-mediated Vasodilatation (FMD)
- Trial name
- PAPCOPDHS (NCT00949195)
- Testing
- Measure pulmonary artery pressure change during exercise, Pulmonary pressure response during exercise
- Where
- Hungary
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Szeged University
Body Mass Index Quantitative Trait Locus 8 Disorder, Tangier Disease
High Protein Weight Loss Diet, High Sensitivity C-Reactive Protein and Cardiovascular Risks Among Obese Women
The investigators aimed to determine the effects of HP diet on CVD risk factors and hs-CRP among overweight and obese women.
- Trial name
- NCT01763528
- Testing
- nutrition intervention
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Metabolic Disease
Husk Fiber Intervention on Metabolic Health of Centrally Obese School Teachers
A group of 120 school teachers (male=60, female=60) was divided into four subgroups for sixteen weeks of an interventional study. One group was kept in control while the other three groups were assigned intervention.
- Trial name
- NCT06188728
- Testing
- effect of 10 gm psyllium husk fiber twice a day, 30 minutes before breakfast and dinner, Effect of life style modification (Diet, Behavior and physical activity), Combined effect of 10 gm Psyllium husk fiber and lifestyle modification
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Peshawar
Healthy
Study to Evaluate the Effect of Botanical Dietary Supplements on Inflammation in Healthy People
The purpose of the study is to evaluate the effect of botanical dietary supplements on inflammation in healthy people with different genetic responses to inflammation.
- Trial name
- NCT00303238
- Testing
- Rose hips extract + blueberry/blackberry extract + resveravine, Rose hips extract + blueberry/blackberry extract + Aframomum melegueta extract, Rose hips extract + resveravine + Aframomum melegueta extract
- Where
- 8 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Access Business Group
Gingivitis
Efficacy of a Naturally-derived Mouthrinse for Gingival Inflammation
Gingivitis, defined as inflammation of the gingival tissues, has long been associated with bacterial accumulation [plaque] on the tooth surface adjacent to the gingiva, causing an inflammatory reaction.
- Trial name
- NCT00885599
- Testing
- Herbal API, Cepacol, Listerine Antiseptic Mouth Rinse
- Where
- Israel
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Cognition, Affect (Mental Function)
BiomeBakery Project
This study aims to investigate the chronic effects of prebiotic fibre-fortified functional bakery product on cognitive, affective, inflammatory, metabolic, and anthropometric outcomes in healthy adults aged 60-75 years with mild…
- Conditions
- Cognition, Affect (Mental Function), C Reactive Protein
- Trial name
- NCT06796712
- Testing
- Prebiotic fibre fortified bread roll, Regular bread roll
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Reading
Healthy
A Study to Evaluate the Effect of Astaxanthin in Healthy Participants
Astaxanthin is recognized as a bioactive compound with potential benefits for human health. This study aims to evaluate a specific nutritional supplement impact on markers of oxidative stress, inflammation, lipid levels, blood…
- Trial name
- NCT05376501
- Testing
- Astaxanthin
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- LycoRed Ltd.
Rheumatoid Arthritis
Can Cytokines be Used as an Activation Marker
RA is a chronic, autoimmune, inflammatory disease that involves small joints in the form of symmetrical polyarthritis and progresses with exacerbations and remissions.
- Trial name
- NCT04486027
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Inguinal Hernia, Indirect, Children, Only
Inflammatory Stress Response in Pediatric Inguinal Hernia Repair
Today there are various surgical techniques for inguinal hernia. In this study, investigators want to compare the ''PIRS'' operating technique laparoscopy and modified "Marcy" operating technique with open inguinal access.
- Conditions
- Inguinal Hernia, Indirect, Children, Only, Inflammatory Response, Surgery
- Trial name
- NCT03203343
- Testing
- Operation - PIRS, Operation - MARCY
- Where
- Croatia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital of Split
Lipedema, Inflamation
Investigation of Systemic Inflammation Markers in Lipedema
The aim of this study is to evaluate systemic inflammation in individuals with lipedema using hematological and biochemical inflammation indices and to examine the relationship between these indices and clinical findings.
- Conditions
- Lipedema, Inflamation, Inflammation Biomarkers, Obesity & Overweight
- Trial name
- NCT07787234
- Testing
- Clinical parameters, Laboratory parameters
- Where
- Turkey (Türkiye)
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Coronary Heart Disease, Periodontitis
Effect of Non-surgical Periodontal Treatment on Cardiovascular Risk Markers
The research question was to investigate whether non-surgical periodontal therapy could reduce cardiovascular risk markers in Coronary heart disease (CHD) patients.
- Trial name
- NCT04305171
- Testing
- non-surgical periodontal treatment
- Where
- 3 sites in Thailand
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Healthy and Acutely Ill Children & Adults
Technical Accuracy and Userfriendliness of Two Point-of-care C Reactive Protein Devices in Comparison With Laboratory CRP Testing.
Study to test technical accuracy and userfriendliness of two Point-of-care C Reactive Protein devices (POC CRP devices) in comparison with laboratory CRP testing on children and adults. Research questions: 1.
- Trial name
- NCT01667172
- Testing
- Point-of-Care C Reactive Protein measurement on capillary blood
- Where
- 3 sites in Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Diet, Healthy
Red Palm Olein on Inflammation and Gut Health
A parallel intervention was conducted to test the effect of consuming diets enriched with red palm olein (RPOO), extra virgin coconut oil (EVCO) and extra virgin olive oil (EVOO; positive control) in centrally obese individuals…
- Trial name
- RPO (NCT05791370)
- Testing
- A 12-week parallel dietary intervention
- Where
- Malaysia
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
Obesity, Diabetes
Calorie Restriction and Changes in Body Composition, Disease, Function, and Quality of Life in Older Adults
The investigators want to determine if the benefits of weight loss outweigh the potential risk in a group of older adults. The investigators will test the hypothesis that changes in diet composition alone or in conjunction with…
- Conditions
- Obesity, Diabetes, Hypertension, Hyperlipidemia
- Trial name
- CROSSROADS (NCT00955903)
- Testing
- Exercise, Reduced Calorie Diet, Weight Maintenance Diet
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obesity
Glycomacropeptide and Women's Health
This is a study about how a dietary supplement containing a whey protein affects hormones controlling hunger and satiety (leptin and ghrelin) in postmenopausal women with a body mass index between 28 and 35 kg/m2.
- Trial name
- GMP (NCT05551091)
- Testing
- glycomacropeptide (GMP)
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison