Clinical trials: C Section
Cesarean Section, Adhesions
Closure of Peritoneum at Cesarean Section and Postoperative Adhesion
Objective: To determine the effect of non-closure of the visceral and parietal peritoneum during Cesarean section on the formation of adhesions.
- Trial name
- cs adhesions (NCT01183000)
- Testing
- Closure of the peritoneum at cs
- Where
- 2 sites in Israel
- Volunteers
- 533 people, healthy volunteers welcome
- Sponsor
- Barzilai Medical Center
Hypotension, Hypertension
Norepinephrine ED90 Bolus After Spinal Anesthesia in Cesarean Section
The investigators are aiming to determine what is the effective intravenous dose required of an initial bolus of norepinephrine prior to a maintenance infusion to prevent a 20% decrease in maternal blood pressure from baseline…
- Conditions
- Hypotension, Hypertension, Nausea, Pain
- Trial name
- NCT06574555
- Testing
- Norepinephrine
- Where
- Chile
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Cesarean Delivery, Personality Beliefs
Personality and Anesthesia Preferences in Cesarean Delivery
Cesarean deliveries (CD) under general anesthesia are still common despite higher risks. Clinical guidelines recommend neuraxial anesthesia, but many patients refuse it due to fear and anxiety.
- Trial name
- NCT06795321
- Testing
- Spinal anesthesia, General anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Cesarean Section, Pain, Acute
Comparison of Intrathecal Morphine With the Quadratus Lumborum Type 2 Block for Post-operative Analgesia Following Elective Caesarean Section (QLBvITM Study)
The investigators are comparing post operative analgesia provided for caesarean section patients, with the quadratus lumborum type 2 block and intrathecal morphine.
- Trial name
- NCT03267628
- Testing
- Intrathecal morphine as well as local anaesthetic in Blocks, Intrathecal morphine as well as saline in Block, Saline intrathecal as well as saline in Blocks
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dr Willem Basson
Postoperative Pain
Abdominal Wall Local Anesthesia to Maximize Postoperative Pain Control After Cesarean Delivery
This study has been designed to determine if women undergoing cesarean delivery with spinal anesthesia and routine pain management who also have an additional ultrasound guided transversus abdominis plane (TAP)block using…
- Trial name
- NCT01261637
- Testing
- Ropivicaine
- Where
- Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Surgical Site Infection, Cesarean Section; Complications, Wound, Infection (Following Delivery)
The Use of Steri3X for Prevention of Post-operative Wound Infections in Cesarean Sections
Postpartum infection if a major cause of maternal morbidity and mortality and surgical site infections are some of the common complications following cesarean section.
- Conditions
- Surgical Site Infection, Cesarean Section; Complications, Wound, Infection (Following Delivery), Postpartum Complication
- Trial name
- NCT05392400
- Testing
- Steri3X, Control
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Postpartum Hemorrhage, Cesarean Section Complications
The Impact of Mechanical Methods on the Postpartum Haemorrhage Prophylaxis During Caesarean Section
The rate of heavy blood loss is higher in Cesarean delivery compared to vaginal deliveries. Since postpartum hemorrhage is a life threatening situation to decrease the maternal mortality and morbidity rates, precautions should be…
- Trial name
- NCT05948436
- Testing
- Clamping the uterine artery bilaterally during Cesarean section
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Obstetric Anesthesia Problems, Bupivacaine Adverse Reaction
Thoraco Lumbar Vertebral Length and Bupivacaine Dosage in C-Section
Our hypothesis is that the bupivacaine dose determined according to the thoracolumbar vertebral body length (VBL) is more effective in achieving a lower hypotension rate during spinal anesthesia for cesarean delivery than the…
- Trial name
- bupivacaine (NCT06869434)
- Testing
- Group VBL (Thoracolumbal vertebral body length) received 0.2 mg x VBL cm of %0.5 hyperbaric bupivacaine, Group FD (fixed dose) received a volume of 0.5% hyperbaric bupivacaine based on a dose calculated according to the patient's height 0.065 mg/cm, Group AD (adjusted dosage) got intrathecal heavy bupivacaine (0.5%) tailored to the patient's height and weight.
- Where
- Turkey (Türkiye)
- Volunteers
- 446 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Hypothermia, Newborn
Influence of Duration Since Birth Until Admission to Well-baby Nursery on Neonatal Temperature at Admission
The investigators will collect the time interval from birth to arrival to WBN or NICU, the time interval from arrival to nurse admission, the first measured temperature, and the week of birth.
- Trial name
- NCT05505903
- Testing
- Temerature measurement
- Where
- Israel
- Volunteers
- 2,412 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Postpartum Hemorrhage
Pharmacokinetics of Oxytocin at Cesarean Delivery
The primary objective is to obtain data to inform the design of a population pharmacokinetic study of oxytocin after administration at CD as per standard institutional practice.
- Trial name
- Peacocks (NCT03898882)
- Testing
- oxytocin, Shore durometer
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Aspiration; Gastric Contents, Anesthesia
An Evaluation of a Liberal Hydration Regimen Before Elective Caesarean Section Using Beside Gastric Ultrasound
The aim of this study is to compare the residual gastric volumes in non-labouring parturients prior to elective Caesarean delivery when fully fasted as per European Society of Anaesthesia pre-operative fasting guidelines against…
- Trial name
- NCT05783427
- Testing
- liberal hydration
- Where
- Ireland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Coombe Women and Infants University Hospital
Anemia
Milking the Umbilical Cord at Term Cesarean Birth
The purpose of this pilot study is to determine if umbilical cord milking at the time of scheduled cesarean section effects the hemoglobin and hematocrit levels of full-term infants as determined by hemoglobin and hematocrit…
- Trial name
- NCT01630993
- Testing
- Umbilical Cord Milking
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Pregnancy, Cesarean Delivery
Transthoracic Echocardiographic Monitoring of Cardiac Output Effects of Colloid Preload and Crystalloid Coload During Cesarean Delivery Under Spinal Anesthesia
Transthoracic echocardiography (TTE) has been introduced in anesthesia and intensive care practice to assess the volume status and predict fluid responsiveness, with a few studies performed on pregnant women (5).
- Conditions
- Pregnancy, Cesarean Delivery, Spinal Anesthesia Induced Hypotension, Cardiac Output Measurement
- Trial name
- NCT06654687
- Testing
- Transthoracic Echocardiography, Ringer lactate 1000 ml, Albumin
- Where
- Egypt
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Sameh Fathy
Intrauterine Device
Misoprostol for Cervical Ripening Before Copper Intrauterine Device Removal
Intrauterine devices are the most common used method of contraception in the world, mostly in developing countries, because they offer long-term, reversible and relatively safe contraception.
- Trial name
- NCT03600064
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Pain
A Comparative Study of Intrathecal Magnesium Sulphate & Midazolam With Epidural Ropivacaine for Caesarean Patients
This study compares whether addition of Magnesium or Midazolam intrathecally to epidurally administered isobaric Ropivacaine improves the quality of blockade, haemodynamics and duration of analgesia post-operatively.
- Trial name
- NCT02619799
- Testing
- intrathecal magnesium sulphate,, Intrathecal midazolam
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rangaraya Medical College
Cesarean Delivery
IC-CS Risk: Patient Outcomes
This study is looking at the impact of the implementation of a cesarean risk calculator on cesarean delivery and maternal morbidity rates.
- Trial name
- NCT06488092
- Testing
- Cesarean Risk Calculator
- Where
- 14 sites in United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Tocophobia, Pregnancy Complications
Tokophobia ; Our Clinical Experience
Fear of childbirth, or what has historically been called tokophobia, is often described as a severe fear of birth and pathological fear of childbirth.
- Trial name
- NCT05627336
- Testing
- pregnant women in the 3rd trimester
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Breast Feeding, Exclusive
Rotation and Movement System, Postpartum Cesarean Sections
In the first half hour of a cesarean advertisement, the service-oriented mother will not be mobile and will need support to get fit in bed and start getting started.
- Trial name
- Rotation (NCT05499208)
- Testing
- Giving side position with patient turning and movement system
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kars Harakani State Hospital
Hypotension, Spinal Anesthesia
Pupillary Light Reflex to Predict Post-Spinal Hypotension in Elective Cesarean Delivery
This prospective observational cohort study investigates whether pre-anesthetic pupillary light reflex (PLR) parameters can predict the risk of hypotension following spinal anesthesia in women undergoing elective cesarean…
- Conditions
- Hypotension, Spinal Anesthesia, Cesarean Delivery
- Trial name
- NCT07678723
- Testing
- Not applicable- observational study
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Pregnancy, Obesity
Investigation of Continuous Versus Interrupted Subcutaneous Fat Closure in Reducing Surgical Site Infection
This research aims to clarify the best way to perform subcutaneous tissue closure in overweight and obese patients undergoing caesarean section to reduce the occurrence of surgical site infections.
- Trial name
- NCT05856968
- Testing
- continuous subcutaneous tissue closure, Interrupted subcutaneous tissue closure
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
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