Clinical trials: C-REACTIVE PROTEIN
Atrial Fibrillation, Stroke
Colchicine in Atrial Fibrillation to Prevent Stroke
The purpose of this study is to determine the feasibility of performing a randomized controlled trial to investigate the efficacy of an anti-inflammatory drug, colchicine, at reducing well validated markers of thrombosis…
- Trial name
- CIAFS-1 (NCT02282098)
- Testing
- Colchicine
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Population Health Research Institute
Children
Children With Fever and Respiratory Symptoms at Out-of-hours Services in Norway
Viral self-limiting infections in respiratory organs among children are common in primary care. Serious infections have low prevalence and are challenging to distinguish from self-limiting infections.
- Trial name
- NCT02496559
- Testing
- Pre-consultation CRP
- Volunteers
- 401 people
- Sponsor
- NORCE Norwegian Research Centre AS
Acute Appendicitis
Acute Appendicitis: The Influence of C-reactive Protein and Leucocytes on Clinical Decision-making
Aim: To investigate if the results of CRP and leucocytes had any positive or negative influence on the surgeon's decision-making when handling patients with suspected AA.
- Trial name
- NCT02304653
- Testing
- Clinical descision making
- Where
- Denmark
- Volunteers
- 226 people
- Sponsor
- Odense University Hospital
Metabolic Disease
Effect of Aerobic Exercise Associated With Abdominal Laser Therapy
The purpose of the present study was to evaluate the effects of one session of aerobic exercise associated with low level laser therapy in lipolytic activity, lipid profile and inflammatory markers (C-reactive protein - CRP).
- Trial name
- NCT03462537
- Testing
- Low level laser therapy, Aerobic Exercise, Low level laser therapy without power
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
Pancreatic Fistula After Pancreaticoduodenectomy, C-Reactive Protein
Postoperative Pancreatic Fistula in Patients Undergoing Pancreaticoduodenectomy
Pancreaticoduodenectomy (PD) is a complex procedure performed in patients with malignant or benign tumors of the pancreatic head and periampullary region, associated with high morbidity and mortality.
- Conditions
- Pancreatic Fistula After Pancreaticoduodenectomy, C-Reactive Protein, Albumin
- Trial name
- popf (NCT06300801)
- Testing
- Is the preoperative c-reactive protein/albumin ratio successful in predicting postoperative pancreatic fistula in patients undergoing pancreatoduodenectomy?
- Where
- 2 sites in Turkey (Türkiye)
- Sponsor
- Erol Olcok Corum Training and Research Hospital
Coronary Heart Disease, Unstable Angina
Fecal Microbiota and Monocyte Trained Immunity in CHD Patients With Different hsCRP
This single-center study enrolled patients aged 35-75 years who were diagnosed with unstable angina (UA), and had at least one of the three major coronary arteries with a ≥ 50% reduction in lumen diameter by angiographic visual…
- Trial name
- NCT06562309
- Testing
- take feces and blood samples from patients
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Treatment Resistant Depression (TRD), Inflammation
TACS on High-inflammatory and Refractory Depression
This study is a randomized controlled trial with a duration of 12 weeks (4 weeks of intervention + 8 weeks of follow-up). The participants are patients with treatment-resistant depression (TRD) and high inflammatory activity…
- Trial name
- NCT06812923
- Testing
- transcranial Alternating Current Stimulation (tACS)
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Tianjin Anding Hospital
Acute Febrile Illness, Use of Antimicrobial Agents
Comparison of Rates of Antimicrobial Use in Febrile Patients With or Without the Use of C-reactive Protein Blood Test
In Health Posts of rural areas operated by the Government of Nepal, there are limitations of tests to differentiate between bacterial and viral infections.
- Conditions
- Acute Febrile Illness, Use of Antimicrobial Agents, C-reactive Protein Level
- Trial name
- CREATIB (NCT05292508)
- Testing
- C-reactive Protein Rapid Diagnostic Test
- Where
- Nepal
- Volunteers
- 924 people
- Sponsor
- Patan Academy of Health Sciences
Sepsis, SIRS
Performance Evaluation of the Nanomix eLab® CRP, PCT, and LAC Assays With the Nanomix eLab System
The performance of the eLab C-Reactive Protein, Procalcitonin, and Lactate Assays will be demonstrated during a method comparison study in which venous whole blood and plasma samples are used.
- Trial name
- NCT03876535
- Testing
- Nanomix eLab® System molecular diagnostic test (non-interventional)
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- Nanomix
Metabolic Syndrome
In Vitro Fertilization Outcomes in Metabolic Syndrome
The purpose of this study is to examine the effect of metabolic syndrome in over-weight women on IVF treatment outcomes.
- Trial name
- NCT01958424
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
End Stage Kidney Disease (ESKD)
A Phase 1b Study to Evaluate the PK of CSL300 (Clazakizumab) in Chinese Subjects With End Stage Kidney Disease (ESKD)
This is a phase 1b, partial-blind (Sponsor unblinded), randomized, multicenter, placebo-controlled study. The primary objective of this study is to evaluate the pharmacokinetics (PK) of CSL300 after single and multiple doses in…
- Trial name
- NCT07619820
- Testing
- CSL300
- Where
- China
- Volunteers
- 24 people
- Sponsor
- CSL Behring
Given Indication for Open Resection of Colorectal Cancer
Diagnostic Value of C-reactive Protein and White Blood Cell Counts for Early Detection of Inflammatory Complications After Open Resection of Colorectal Cancer
Although widely used, there is a lack of evidence concerning diagnostic value of C-reactive protein (CRP) and white blood cell counts (WBC) in the postoperative course.
- Trial name
- NCT01221324
- Volunteers
- 1,200 people
- Sponsor
- Cantonal Hospital of St. Gallen
Acute Coronary Syndrome
High Sensitive C-reactive Protein to Albumin Ratio in Acute Coronary Syndrome
assess the use of hs- C-reactive protein to albumin ratio (hs-CAR) in prediction of in-hospital short-term major adverse cardiac events (MACEs) in acute coronary syndrome (ACS) patients
- Trial name
- NCT06673381
- Where
- Egypt
- Volunteers
- 240 people
- Sponsor
- Sohag University
Arthritis, Rheumatoid, Periodontitis
Periodontal Therapy in Patients With Rheumatoid Arthritis
Aim: A prospective randomized, controlled clinical trial comparing two groups of a cohort of Rheumatoid Arthritis (RA) patients with periodontal disease will be carried out to identify if the effect of non-surgical periodontal…
- Trial name
- NCT05502601
- Testing
- Non-surgical periodontal treatment
- Where
- Peru
- Volunteers
- 42 people
- Sponsor
- Federal University of Rio Grande do Sul
Nasopharyngeal Carcinoma, Head and Neck Cancer
The Association of hsCRP and Radiotherapy-Induced Toxicity in Patients With Nasopharyngeal Carcinoma
The primary purpose of this study is to explore the association of high sensitivity C-reactive protein (hsCRP) and radiotherapy(RT)-induced toxicity in patients with nasopharyngeal carcinoma.
- Conditions
- Nasopharyngeal Carcinoma, Head and Neck Cancer, Toxicity Due to Radiotherapy
- Trial name
- NCT04303975
- Testing
- clinical measurements
- Volunteers
- 300 people
- Sponsor
- Jiarong Chen, MD
Obesity
Effect of Endurance and Endurance-Strength Training on Inflammatory Markers in Women With Abdominal Obesity
The aim of this study was to compare the effects of three months' endurance training and three months' endurance-strength training on inflammatory markers in women with abdominal obesity.
- Trial name
- ENDOFIT (NCT03444207)
- Testing
- Endurance training, Endurance-strength training
- Where
- Poland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Acute Kidney Injuries
C-reactive Protein & Albumin Ratio IN AKI
Acute pancreatitis (AP), defined as acute inflammation of the pancreas, it's one of the most common diseases of the gastrointestinal tract leading to hospital admission.(1) The global incidence of AP is reported between 20 and 40…
- Trial name
- NCT07335757
- Testing
- C-reactive protein to albumin ratio
- Volunteers
- 150 people
- Sponsor
- Assiut University
Cognition, Affect (Mental Function)
BiomeBakery Project
This study aims to investigate the chronic effects of prebiotic fibre-fortified functional bakery product on cognitive, affective, inflammatory, metabolic, and anthropometric outcomes in healthy adults aged 60-75 years with mild…
- Conditions
- Cognition, Affect (Mental Function), C Reactive Protein
- Trial name
- NCT06796712
- Testing
- Prebiotic fibre fortified bread roll, Regular bread roll
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Reading
Periodontitis
Impact of C-reactive Protein on Non Surgical Periodontal Treatment
In light of the controversy that are already approved but that however still exists regarding the efficacy and influence the management of Periodontitis, the aim of this study was to evaluates, at 12-months follow-up, the…
- Trial name
- NCT05836298
- Testing
- Non-surgical periodontal treatment
- Where
- Italy
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Catania
Systemic Infection
Efficacy and Safety of a Protocol Using C-reactive Protein to Guide Antibiotic Therapy
The growing resistance of microorganisms to antimicrobials is a major threat to public health nowadays. Reducing the consumption of antibiotics is one of the main strategies to control this issue.
- Trial name
- NCT05841875
- Testing
- C reactive protein algorithm
- Where
- Brazil
- Volunteers
- 110 people
- Sponsor
- Federal University of Minas Gerais