Clinical trials: C-Section
Postpartum Hemorrhage
Oxytocin i.m./i.v. Versus Carbetocin i.v. in Elective Cesarean Sections
Objective is to proof non-inferiority of intramyometrial and intravenous oxytocin application compared to intravenous carbetocin for prevention of postpartum hemorrhage in planned, uncomplicated cesarean deliveries.
- Trial name
- NCT03651882
- Testing
- Oxytocin, Carbetocin
- Where
- Switzerland
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Postoperative Pain
Prediction of Post-Cesarean Section Pain
The purpose of this study is to determine if dynamic psychophysical testing along with genetic screening will allow to identify pre-operatively women who will suffer severe acute pain post-operatively and the subset who may…
- Trial name
- PPCSP (NCT00799162)
- Testing
- Psychophysical testing, questionnaires, and genetics
- Where
- 5 sites in United States, Belgium and 2 more
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Washington
Pregnancy, Neonatal Hearing Function
Comparison of Different Anesthetic Techniques on Hearing Outcomes in Neonates After Cesarean Delivery
This is a single-center, prospective, single-blind randomized controlled trial. The investigators plan to recruit 144 pregnant women scheduled for cesarean delivery.
- Trial name
- ATHNCD (NCT07852624)
- Testing
- Combined spinal-epidural anesthesia, General Anesthesia (GA)
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Skin Wound Healing After Cesarean Section, Cesarean Section Scar Healing
Tissue-Engineered Construct Based on Amniotic Membrane and Calcium Alginate for Cesarean Section Wound Healing
This clinical trial aims to evaluate the safety and efficacy of an experimental tissue-engineered construct (TEC) based on amniotic membrane and calcium alginate for promoting epithelialization and improving scar quality in…
- Trial name
- NCT07241013
- Testing
- Tissue-engineered construct based on amniotic membrane and calcium alginate (TEC)
- Where
- Kazakhstan
- Volunteers
- 100 people
- Sponsor
- Asfendiyarov Kazakh National Medical University
Cesarean Section Wound, Platelet-rich Plasma (PRP)
Efficacy of Platelet-rich Plasma in Improving Postoperative Scarring After Cesarean Delivery
Cesarean section often leads to postoperative scarring, which can impact both physical and psychological well-being. Platelet-rich plasma (PRP), rich in growth factors, is used in regenerative medicine to promote healing and…
- Conditions
- Cesarean Section Wound, Platelet-rich Plasma (PRP), Regenerative Medicine
- Trial name
- PRP06081992 (NCT06978010)
- Testing
- Platelet-Rich Plasma (PRP) intraoperatively
- Where
- Romania
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saint Andrew Hospital Constanta
Cesarean Section
Intraperitoneal Saline Irrigation in Cesarean Section
The study evaluates the effect of intraperitoneal saline irrigation before abdominal closure during cesarean section on postoperative infectious morbidity and the incidence of paralytic ileus.
- Trial name
- NCT07730060
- Testing
- Intraperitoneal Saline Irrigation
- Volunteers
- 150 people
- Sponsor
- Assiut University
Surgical Site Infection (SSI), Cesarean Section Wound
Subcutaneous Drain Versus Wound Irrigation by Normal Saline for Prevention of Surgical Site Infection Following Caesarean Section in Obese Patients.
This is a prospective randomized controlled trial conducted at Ain Shams University Maternity Hospital to compare subcutaneous drain versus wound irrigation with normal saline for the prevention of surgical site infection…
- Trial name
- NCT07517718
- Testing
- Subcutaneous Drain, Normal Saline
- Where
- Egypt
- Volunteers
- 189 people
- Sponsor
- Ain Shams University
Cesarean Section Complications
Laparoscopic Repair of Cesarean Scar Niche
Evaluation of laparoscopy repair of cesarean scar niche in resolution of symptoms related to niche as compared to expectant management.
- Trial name
- NCT04307524
- Testing
- laparoscopic repair, medical treatment in the form of combined hormonal contraception
- Volunteers
- 30 people
- Sponsor
- Zagazig University
C-Section, Pain Management
Evaluate the Safety and Efficacy of EXPAREL When Administered Via Infiltration Into the TAP vs. Bupivacaine Alone in Subjects Undergoing Elective C-Sections
Primary objective: The primary objective of this study is to compare total opioid consumption through 72 hours following EXPAREL+bupivacaine HCl infiltration into the transversus abdominis plane (TAP) after spinal anesthesia to…
- Trial name
- C-Section (NCT03176459)
- Testing
- Exparel + Bupivacaine, Bupivacaine
- Where
- 12 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Pacira Pharmaceuticals, Inc
Caesarean Section
The Effect of Su Jok Application on Pain, Anxiety and Comfort Levels After Cesarean Section
Objective: To determine the effect of Su Jok application on pain, anxiety and comfort level after cesarean section. The research will be conducted as a randomized controlled experimental study with pretest-posttest control group
- Trial name
- NCT07091760
- Testing
- Su Jok Application
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Blood Antibiotic Levels
Preventive Antibiotic Serum Levels During Caesarean Section
Background Preventive antibiotic treatment before performing invasive procedures is a basic element in preventing infections. The essence of preventive antibiotic treatment is strengthening the defense mechanisms of the immune…
- Trial name
- NCT02838940
- Testing
- Blood samples., Cefazolin
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cesarean Section Wound
Bilevel Erector Spinae Plane Block Versus Transversus Abdominis Plane Block for Analgesia After Cesarean Delivery.
Optimizing analgesia after cesarian delivery is an essential element of enhancing maternal recovery.A multimodal analgesic approach incorporating truncal blocks can provide effective pain relief with minimal side effects for both…
- Trial name
- NCT07137208
- Testing
- ESP block, TAP Block, Bupivacaine injection
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Postpartum Contraception
New Method of IUD Insertion During Cesarian Section
In women undergoing elective CS, half of them will have Intra-caesarian copper T 380 IUD insertion using the standard method and the remaining half will undergo copper T 380 IUD insertion during CS using a new technique in order…
- Trial name
- NCT05756998
- Testing
- Copper T380 IUD ( Paragard 380 A ,CooperSurgical, Inc. © 2022) (classic technique), Copper T380 IUD ( Paragard 380 A ,CooperSurgical, Inc. © 2022) ( New technique), cesarian section
- Where
- Egypt
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pregnancy
Postoperative Morphine Consumption After Caesarean Section- TAP Block vs Intracutaneous Infiltration
The purpose of this study is to investigate whether a regional-block (TAP block) in Caesarean section will give a measurable benefit in form of reducing Morphine consumption as compared to local infiltration of the wound with…
- Trial name
- NCT01674114
- Testing
- TAP block, control
- Where
- Norway
- Volunteers
- 57 people
- Sponsor
- St. Olavs Hospital
Complications After Cesarean Section
Enemas Before Elective Cesarean Section
Enemas are not anymore used routinely before vaginal deliveries.The intention of this study is to elucidate whether there is a benefit in routine use of enema before cesarean section.
- Trial name
- NCT00391599
- Testing
- enema
- Volunteers
- 130 people
- Sponsor
- Wolfson Medical Center
Cesarean Section, Postoperative Recovery
Enhanced Recovery Protocol Compliance and Quality of Recovery After Cesarean Delivery
This prospective observational study will evaluate whether adherence to enhanced recovery after cesarean delivery protocols is associated with postoperative recovery quality in women undergoing elective cesarean delivery under…
- Conditions
- Cesarean Section, Postoperative Recovery, Postoperative Pain
- Trial name
- ERAC-QoR (NCT07790471)
- Testing
- Assessment of Enhanced Recovery Protocol Compliance
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bursa City Hospital
Chronic Postoperative Pain, Cesarean Section Complications
Monocentric Observational Study: Postoperative Pain After Cesarean Section: Incidence and Risk Factors.
The purpose of this prospective study was to assess chronic pain 3, and 12 months after cesarean delivery in a cohort of women in University hospital La Paz.
- Trial name
- NCT04280432
- Testing
- CESAREAN
- Where
- Spain
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Preoperative Anxiety, Postpartum Pain
QR Code-Based Preoperative Education for Cesarean Birth: Anxiety, Pain, and Comfort
This study aims to evaluate the effect of QR code-based preoperative education on anxiety, postpartum pain, and comfort levels in women undergoing cesarean birth.
- Conditions
- Preoperative Anxiety, Postpartum Pain, Maternal Comfort, Cesarean Birth
- Trial name
- NCT07368387
- Testing
- QR Code-Based Preoperative Education
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Postdural Puncture Headache (PDPH)
Oral Gabapentin Versus Intravenous Neostigmine/Atropine Versus Combination of Both for Prevention of PDPH
Post-dural puncture headache (PDPH) is a major complication of neuraxial anaesthesia. Pain is intense, frontal, throbbing, and radiates to the occiput; it is more severe when standing and less severe when lying down.
- Trial name
- NCT07916116
- Testing
- treatment of Postdural puncture headache
- Where
- Egypt
- Volunteers
- 292 people
- Sponsor
- Assiut University
Infection; Cesarean Section
Betadine Irrigation in Cesarean Section
The purpose of this study was to evaluate, for the first time in Literature, the effects of betadine washing versus normal saline washing after uterine closure in women undergoing cesarean section (CS) at ≥36 gestational weeks in…
- Trial name
- NCT02865993
- Testing
- betadine group, no betadine group
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Campus Bio-Medico University
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