Clinical trials: CABG, open to volunteers
Coronary Artery Bypass Grafting (CABG) Surgery, Coronary Artery Disease
Prospective Study Protocol for Multiparametric PCCT Assessment of Early Ventricular Outcomes After CABG
The goal of this observational study is to learn whether information about heart muscle tissue from preoperative photon-counting CT, a newer type of CT scan, can help predict heart recovery 3 months after coronary artery bypass…
- Trial name
- PCCT-CABG (NCT07883499)
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xin Lou
Coronary Artery Disease, Coronary Artery Bypass Graft (CABG)
Photobiomodulation in Coronary Artery Bypass Grafting With No-Touch vs Conventional Saphenous Vein Harvesting.
This randomized, double-blind clinical trial aims to evaluate the impact of photobiomodulation therapy on postoperative outcomes in patients undergoing coronary artery bypass grafting (CABG).
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Graft (CABG), Surgical Wound Healing
- Trial name
- PHOTON (NCT07699679)
- Testing
- Photobiomodulation Therapy, Conventional Saphenous Vein Harvesting, No-Touch Saphenous Vein Harvesting
- Where
- Brazil
- Volunteers
- 292 people
- Sponsor
- Federal University of São Paulo
Heart Failure, CAD - Coronary Artery Disease
Risk Stratification of MACE in Heart Failure Patients Who Undergoing CABG
PROFILE-HF is a multicenter, observational, prospective study of the clinical course and outcomes of chronic heart failure (HF) and coronary artery disease (CAD) in patients undergoing coronary artery bypass grafting (CABG).
- Conditions
- Heart Failure, CAD - Coronary Artery Disease, CABG
- Trial name
- PROFILE-HF (NCT07480915)
- Where
- Russia
- Volunteers
- 160 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Chronic Postoperative Pain, Chronic Post-Sternotomy Pain
Parasternal Intercostal Nerve Block and Chronic Pain After Cardiac Surgery
Chronic post-sternotomy pain is a common but under-recognised complication of cardiac surgery, reported in roughly 11 to 56 percent of patients and capable of persisting for years after the operation.
- Conditions
- Chronic Postoperative Pain, Chronic Post-Sternotomy Pain, CABG, Sternotomy
- Trial name
- PINB-CPSP (NCT07818512)
- Testing
- Ultrasound-Guided Parasternal Intercostal Nerve Block, Bupivacaine 0.25%
- Volunteers
- 132 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Cardiac Rehabilitation, Heart Failure
Cardiac REhabilitation COhort at the Medicine Campus DaVos to invEstigate Recovery
The RECOVER study, titled Cardiac Rehabilitation Cohort at the Medicine Campus Davos for Exploration of Recovery, is a prospective, non-interventional, monocentric cohort study conducted at the Hochgebirgsklinik Davos.
- Conditions
- Cardiac Rehabilitation, Heart Failure, Cardiac Arrest (CA), ACS (Acute Coronary Syndrome)
- Trial name
- RECOVER (NCT07096973)
- Where
- Switzerland
- Volunteers
- 10,000 people
- Sponsor
- Hochgebirgsklinik Davos
Coronary Artery Disease, Coronary Artery Bypass Graft (CABG)
Hyperpolarized 13C Pyruvate-MRI and FDG-PET in a Single Exam for the Prognosis of Ischemic Cardiomyopathy
This prospective, non-blinded, single-center, translational research study aims to validate a multimodal advanced imaging exam for cardiac viability.
- Trial name
- FDG PET-HP MRI (NCT06814587)
- Testing
- Hyperpolarized 13C Pyruvate Magnetic Resonance Imaging (HP-13C MRI), [¹⁸F]Fluorodeoxyglucose Positron Emission Tomography (FDG-PET), SPECT MPI (Single Photon Emission Computed Tomography Myocardial Perfusion Imaging)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
CABG, Graft Failure
Pilot Trial of Colchicine for Graft Failure in CABG
This is a single-center, prospective, randomized, open-label, assessor-blinded, blank-controlled exploratory (pilot) trial evaluating the feasibility of oral colchicine after coronary artery bypass grafting (CABG).
- Conditions
- CABG, Graft Failure, Colchicine
- Trial name
- CoCAB-Pilot (NCT06802926)
- Testing
- Colchicine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Ruijin Hospital
CAD - Coronary Artery Disease, CABG
A Randomized Controlled Trial: Fuzheng Yangxin Formula for ERAS After CABG
This study aims to evaluate the efficacy and safety of Fuzheng Yangxin Formula (FZYXF) in the treatment of qi-yin deficiency syndrome after coronary artery bypass grafting (CABG), formulate an integrated Chinese and Western…
- Conditions
- CAD - Coronary Artery Disease, CABG, ERAS, Medicine, Chinese Traditional
- Trial name
- FZYXF-RCT-CABG (NCT07781436)
- Testing
- FZYX
- Where
- China
- Volunteers
- 230 people
- Sponsor
- Peking University Third Hospital
Delirium - Postoperative, Inflammation Biomarkers
The Impact of Left Stellate Ganglion Block on Systemic Inflammation and Neuromodulation in CABG Surgery.
((82)) patients scheduled to undergo elective CABG by the same surgical team will be allocated randomly by computer-generated random numbers into two equal groups (n= 41).
- Conditions
- Delirium - Postoperative, Inflammation Biomarkers, Stellate Ganglion Block, CABG
- Trial name
- NCT07776496
- Testing
- Stellate Ganglion Block
- Volunteers
- 81 people
- Sponsor
- OMAR ABDELAZIZ ABOELFADL
CABG, Respiratory Insufficiency
Early Postoperative Physiotherapy to Prevent Respiratory Insufficiency After Elective Heart Surgery
This study aims to determine whether starting respiratory physiotherapy one hour after removal of the breathing tube following elective coronary artery bypass graft (CABG) surgery leads to better recovery than the current…
- Conditions
- CABG, Respiratory Insufficiency, Postoperative Pulmonary Complications (PPCs)
- Trial name
- EPP-CABG (NCT07730034)
- Testing
- Early postoperative physiotherapy, Standard postoperative care
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- Dijana Filipović
Valve Disease, Heart, CABG
Nonintubated Anesthesia for Adult Cardiac Surgery With Cardiopulmonary Bypass
The goal of this prospective, multicenter, randomized clinical trial is to learn whether a nonintubated supraglottic airway anesthesia strategy with early restoration of spontaneous breathing can reduce postoperative pulmonary…
- Trial name
- NIA-Heart (NCT07744009)
- Testing
- Nonintubated Anesthesia Group, Conventional Anesthesia Group
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Coronary Arterial Disease, Coronary Artery Bypass Grafting (CABG) Surgery
ESPB vs SPSIP for Postoperative Analgesia After CABG
This prospective, randomized, active-controlled, double-blind, parallel-group study compares the postoperative analgesic efficacy and safety of ultrasound-guided bilateral Erector Spinae Plane Block (ESPB) versus bilateral…
- Conditions
- Coronary Arterial Disease, Coronary Artery Bypass Grafting (CABG) Surgery, Postoperative Pain Management
- Trial name
- ESP-SPSIP-CABG (NCT07388745)
- Testing
- Ultrasound-guided Erector Spinae Plane Block (ESPB), Ultrasound-guided Serratus Posterior Superior Intercostal Plane Block (SPSIPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Kutahya Health Sciences University
Frailty, Coronary Artery Disease
Funcional Recovery After Minithoracotomy or Sternotomy for CABG in Frail Patients
Frailty is a major predictor of adverse outcomes following coronary artery bypass grafting (CABG), being associated with increased postoperative complications, prolonged hospitalization, delayed functional recovery, and reduced…
- Conditions
- Frailty, Coronary Artery Disease, Coronary Artery Bypass Graft (CABG)
- Trial name
- MINIFRAGILE (NCT07742475)
- Testing
- Minimally Invasive Coronary Artery Bypass Grafting (MICS-CABG), Conventional Coronary Artery Bypass Grafting (Median Sternotomy)
- Volunteers
- 194 people
- Sponsor
- University of Sao Paulo General Hospital
Acute Myocardial Infarction (AMI), Percutaneous Coronary Intervention (PCI)
BRIDGE Trial: Embedding Consumer-grade mHealth Technologies Into Cardiac Rehabilitation
The purpose of the BRIDGE study is to learn whether supplementing traditional center-based cardiac rehabilitation (CBCR) with a mobile health technology intervention can help patients monitor their health, stay engaged in healthy…
- Conditions
- Acute Myocardial Infarction (AMI), Percutaneous Coronary Intervention (PCI), Coronary Artery Bypass Graft Surgery (CABG), Chronic Heart Failure With Reduced Ejection Fraction (HFrEF)
- Trial name
- BRIDGE (NCT07741396)
- Testing
- CBCR, BRIDGE mHealth intervention
- Volunteers
- 30 people
- Sponsor
- University of Illinois at Chicago
Coronary Artery Bypass Grafting (CABG) Surgery, Saphenectomy
Adductor Canal Block: Efficacy in Postoperative Pain Management for Cardiac Surgery
Adductor Canal Block: Efficacy in Postoperative Pain Management for Cardiac Surgery
- Trial name
- AddEase (NCT07732465)
- Testing
- Aductor canal bloc, Control adductor canal block
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Montreal Heart Institute
Coronary Artery Disease (CAD), Coronary Artery Bypass Graft Surgery(CABG)
A Clinical Trial To Investigate The Effect Of EA-230 On Hospital Length Of Stay In Patients With Coronary Artery Disease (CAD) Undergoing Coronary Artery Bypass Grafting (CABG) Surgery.
EA-230 is a new therapy that may help people recover faster and have fewer problems after bypass surgery. In an earlier clinical trial, participants who received EA-230 during Coronary Artery Bypass surgery stayed in the…
- Trial name
- EasyBoost (NCT07357675)
- Testing
- EA-230 90mg/kg/hour
- Where
- 6 sites in United States, Belgium and 2 more
- Volunteers
- 300 people
- Sponsor
- EBI Anti Sepsis BV
Coronary Artery Bypass Grafting (CABG) Surgery, Heart Valve Surgery
From Prehabilitation to Rehabilitation (Prehab2Rehab): Digitally Supported Short-Term Prehabilitation Prior to Cardiac Surgery
Prehab2Rehab is a prospective single-arm feasibility study evaluating the implementation of a multimodal, digitally supported prehabilitation program for adults awaiting elective cardiac surgery.
- Conditions
- Coronary Artery Bypass Grafting (CABG) Surgery, Heart Valve Surgery, Surgical Closure of an Atrial Septal Defect (ASD)
- Trial name
- Prehab2Rehab (NCT07716761)
- Testing
- Digitally supported prehabilitation program
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Ludwig Boltzmann Institute for Digital Health and Prevention
CABG
Structured Inpatient Physiotherapy in High-Risk Coronary Artery Bypass Grafting Patients
Coronary artery bypass grafting (CABG) may be associated with prolonged recovery, particularly in high-risk patients. Although preoperative rehabilitation has shown promising results, evidence remains limited because of…
- Trial name
- NCT07725887
- Testing
- Preoperative and Postoperative Structured Inpatient Physiotherapy, Postoperative Structured Inpatient Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bezmialem Vakif University
ERAS, Cardiac Surgery
Impact of a Technology Platform Based on Enhanced Recovery After(ERAS) Surgery on Length of Stay After Coronary Artery Bypass Grafting: Timely Project
Cardiovascular diseases continue to be the leading cause of death worldwide. Among them, coronary artery disease has the greatest impact, being characterized as one of the main causes of death in Brazil over the last decade.
- Conditions
- ERAS, Cardiac Surgery, Cardiac Surgery-CABG, Digital Health
- Trial name
- REPLICCARIII (NCT06786819)
- Testing
- ERACS with Digital Platform
- Where
- 2 sites in Brazil
- Volunteers
- 480 people
- Sponsor
- University of Sao Paulo General Hospital
Post-Operative Atrial Fibrillation After Coronary Artery Bypass Grafting (CABG)
Colchicine for the Prevention of Post-Operative Atrial Fibrillation After Coronary Artery Bypass Grafting: A Single-Center, Strategy-Stratified, Randomized, Double-Blind, Placebo-Controlled Trial
Post-operative atrial fibrillation after coronary artery bypass grafting (CABG)
- Trial name
- NCT07611019
- Testing
- Colchicine 0.5 MG oral tablet twice daily
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- National Taiwan University Hospital