Clinical trials: CAD-CAM
TMD, Disc Displacement
Conventional, Additive and Subtractive Occlusal Splints for TMDs
This study is aiming to clinically compare between occlusal splints produced by conventional, subtractive and additive techniques in regard to patient satisfaction.
- Trial name
- TMD - TMJ - DD (NCT07371078)
- Testing
- Conventional Stabilizing Splint, Milled Stabilizing Splint, 3D Printed Stabilizing Splint
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Edentulous Maxilla
4 vs 6 Implants in Totally Edentulous Patient in Maxilla With Ti. Cad-cam Framework
The primary objective of the present study is to evaluate the marginal bone level changes occurring in total edentulous patients treated with six or four implants.
- Trial name
- NCT02405169
- Testing
- 4 vs 6 implant treatment in the maxilla
- Where
- Italy
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Institute Franci
Orthodontic Appliances, Adverse Effects,Gingivitis, Dental Plaque, Periodontal Diseases
Digital Manufacturing and Periodontal Performance of CAD/CAM-Customized Orthodontic Molar Bands Compared With Standard Stainless-Steel Bands
his prospective randomized clinical trial aimed to compare periodontal outcomes associated with CAD/CAM-customized orthodontic molar bands and conventional preformed stainless-steel molar bands in adolescents undergoing fixed…
- Trial name
- NCT07526805
- Testing
- Stainless-Steel Orthodontic Molar Bands
- Where
- Romania
- Volunteers
- 180 people
- Sponsor
- Dimitrie Cantemir University
TMD
Clinical Performance of CAD/CAM Splint Materials
The goal of this clinical study is to compare the performance of computer aided designed and computer aided manufactured (CAD/CAM) occlusal splints with splints produced with conventional methods.
- Trial name
- NCT05955222
- Testing
- PEEK, PMMA, Traditional
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Istanbul University
Inlays
This Trial Will Evaluate the Clinical Performance of Onlay Restorations Fabricated Using Rubber Dam Scanning Techniques.
The purpose of this study will be to evaluate the clinical performance of CAD-CAM onlay restorations fabricated using rubber dam scanning techniques up to 12 months and laboratory investigation of their marginal fit.
- Trial name
- NCT05978440
- Testing
- onlay preparation
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Middle Ear Disease
Improved Otologic Implants on Demand Intraoperatively With 3D CAD/CAM Autografts
Prospectively analyze the use of 3D subtraction CAD/CAM in the operating room environment. Study participants, requiring middle ear surgery and ossicular reconstruction, will be implanted with one of two middle ear implants.
- Trial name
- NCT03297736
- Testing
- 3D CAD/CAM autograft prosthesis, Control device
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Nitinetics LLC
Periodontal Disease, Gingival Disease
Evaluation of Gingival Health Parameters in Hybrid CAD / CAM Crowns Produced After Different Retraction Processes
Clinically, the gingival retraction dentistry itself has found wide uses. It has achieved the use of subgingival and gingival crowns in fixed prostheses, cervical abrasion in restorative dentistry, management of root caries and…
- Trial name
- NCT03816930
- Testing
- mechanical cord usage
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Edentulous Jaw, Dental Prosthesis, Implant-Supported
Accuracy of Standard and Geometric Pattern-Assisted Digital Scanning for Full-Arch Implant Prosthesis Frameworks
This clinical trial aims to compare three different impression techniques used to fabricate full-arch implant-supported dental prostheses.
- Conditions
- Edentulous Jaw, Dental Prosthesis, Implant-Supported, Prosthodontics, Dental Implantation, Endosseous
- Trial name
- GPA Scan (NCT07065487)
- Testing
- Intraoral Scanner - Standard Protocol, Intraoral Scanner with Geometric Reference Pattern, Conventional Splinted Impression Technique
- Where
- Egypt
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Mirna ashraf anis heneen
Maxillary Diseases
Patient Satisfaction & Abutment Teeth Health in Maxillectomy Patients
randomized controlled trial in maxillectomy patients with two types of obturators with different manufacturing techniques
- Trial name
- NCT06934551
- Testing
- obturator
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Hyaluronic Acid (HA)
A Comparative Clinical Assessment of Adjunctive Hyaluronic Acid With 3D Printed Versus Milled CAD CAM Provisional Dental Restorations on Active Periodontal Status and Surface Roughness and Biocompatibility
A Comparative Clinical Assessment of Adjunctive Hyaluronic Acid with 3D Printed Versus Milled CAD CAM Provisional Dental Restorations on active Periodontal status and Surface Roughness and biocompatibility (A Randomized…
- Trial name
- NCT07625839
- Testing
- commonly used hyaluronic Acid with both procedures 3D Printed Versus Milled CAD CAM Provisional Dental Restorations
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Implant Site Reaction, Implant Complication
Retention, Chewing Efficiency and Masticatory Performance of Partial Dentures Opposing Implant Retained Prosthesis.
This study aims to evaluate retention ,chewing efficiency and masticatory performance of flexible versus CAD/CAM partial dentures opposing to fixed implant retained restorations.
- Trial name
- NCT05999760
- Testing
- evaluation of retention of Versacryle and CAD/CAM partial dentures by force gauge, chewing efficiency by electromyograph(E.M.G), masticatory performance(questionnaire)
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- National Research Centre, Egypt
Deep Caries Lesion of Pemanent Teeth
Adjustment Period for Partial Crowns
The aim of this study is to compare the occlusal accuracy of CAD/CAM milled and 3D printed crowns guided by an occlusal device, starting from the same digital CAD design.
- Trial name
- Adjustment per (NCT07051590)
- Testing
- cad cam, 3D printer
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ceren Sire
Macrogenia, Microgenia
Evaluation of The Accuracy of CAD-CAM Custom Made Titanium Miniplates In Positioning of the Genial Segment in Computer Guided Genioplasty
In patients with chin deformeties, will using a custom made titanium plate in the positioning of the genial segments give an accurate results in comparison to the preoperative planned osteotomy and move of the Genioplasty.
- Conditions
- Macrogenia, Microgenia, Miniplate
- Trial name
- NCT03647865
- Testing
- Osseous Genioplasty
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Clinical Performance
Clinical Performance of Fiber Reinforced FRC Base and Bonded CAD/CAM Resin Composite Endocrowns Versus Conventional Lithium Disilicate Endocrowns in Posterior Teeth (1y Randomized Clinical Trial).
In patients with endodontically treated molar teeth indicated for endocrown, will the fiber reinforced FRC base and bonded CAD/CAM resin composite endocrowns restorations have a similar clinical performance to the conventional…
- Trial name
- NCT05337358
- Testing
- endocrown
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Discoloration, Tooth Staining
Effectiveness of Dental Bleaching Using Different Designs of 3D-Printed and Conventional Customized Nightguards
This randomized, double-blind, split-mouth clinical trial evaluates the effectiveness of at-home dental bleaching using customized nightguards fabricated by digital (3D-printed CAD-CAM) and conventional methods, with and without…
- Trial name
- NCT07464197
- Testing
- Customized bleaching tray fabrication, Reservoir tray design, Carbamide peroxide 10%
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Partial Edentulism Class 3
Compare CAD/CAM Metallic RPD to Conventional Metallic RPD in Terms of Oral Health Related Quality of Life
Patients will be randomised to receive CAD/CAM metallic removable partial denture (RPD) followed by Conventional metallic RPD (Group A), or the opposite sequence (Group B), with a 3-month wear duration for each denture and…
- Trial name
- NCT06567262
- Testing
- CAD/CAM metallic removable partial denture, Conventional metallic removable partial denture
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Disorders Hard Tissues of Teeth, Tooth Discoloration
Effect of Preparation Design on the Functional and Esthetic Outcome of CAD/CAM Lithium Disilicate Laminate Veneers
Conservatism is considered the main concern in any treatment plan, the feather edge preparation design of laminate veneers have been introduced yet clinical studies are lacking to evaluate their clinical performance.The aim of…
- Trial name
- NCT04840524
- Testing
- Laminate veneers preparation
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Transverse Maxillary Deficiency
Digital vs. Analog Inputs in CAD/CAM Orthodontics: A Comparative Clinical Evaluation of Palatal Expander Fabrication Workflow
36 patients with unilateral or bilateral cross bite treated with hyrax expanders fabricated through three distinct workflows: fully conventional (physical impression + manual fabrication), hybrid (physical impression + CAD/CAM…
- Trial name
- NCT07338591
- Where
- 2 sites in Egypt
- Volunteers
- 36 people
- Sponsor
- Mansoura University
Dental Crowns, Dental Prosthesis
Zirconia and Metal-based Single Crown Posterior Restorations.
The objective of this study was to compare the 5-year survival and clinical behavior of single posterior ceramic crowns made with pressable ceramic on zirconia or on a metal framework.
- Conditions
- Dental Crowns, Dental Prosthesis, Prosthodontics
- Trial name
- NCT02758457
- Testing
- dental crowns
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- University of Bologna
Dental Disorders Hard Tissues of Teeth, Dental Diseases
Clinical Evaluation of Full Contour Zirconia Chairside CAD/CAM Crowns
This investigation will be a randomized, prospective, longitudinal clinical trial to study the clinical performance of a new monolithic, zirconia material with shade, translucency and material graduation for chairside CAD/CAM…
- Trial name
- NCT06173167
- Testing
- Crowns self-adhesively luted, Crowns conventionally cemented
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Ivoclar Vivadent AG