Clinical trials: CAD-CAM
Dental Cements, Caries,Dental
Clinical Performance of Chairside CAD/CAM Restorations
This investigation will be a longitudinal clinical trial to study the long-term clinical performance of a resin cement for chairside CAD/CAM restorations.
- Trial name
- NCT04279574
- Testing
- Lithium disilicate onlays (IPS emaxCAD/Ivoclar), Chairside zirconia crowns (3M)
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Solventum US LLC
Deep Caries Lesion of Pemanent Teeth
Adjustment Period for Partial Crowns
The aim of this study is to compare the occlusal accuracy of CAD/CAM milled and 3D printed crowns guided by an occlusal device, starting from the same digital CAD design.
- Trial name
- Adjustment per (NCT07051590)
- Testing
- cad cam, 3D printer
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ceren Sire
Molar Incisor Hypomineralization
Computer-aided Design/Computer-aided Manufacturing for Mild to Moderate Molar Incisor Hypomineralization Treatment
Molar Incisor Hypomineralization (MIH) is a disease causing a structural defect in the enamel of permanent teeth. The treatment of these teeth consists of the removal of the affected part of the tooth and its reconstitution.
- Trial name
- MIhCFAO (NCT04922177)
- Testing
- Indirect ceramic restoration, Direct restoration
- Where
- France
- Volunteers
- 68 people
- Sponsor
- University Hospital, Toulouse
Denture, Complete
Conventional Versus Neutral-Zone CAD/CAM Dentures Restoring Mandibular Resorbed Ridges
The study is a within-subject randomized clinical trial that will compare and evaluate patients' satisfaction and digitally analyze denture space Confines. Group I: CAD/CAM.
- Trial name
- CAD/CAM (NCT05895292)
- Testing
- CAD/CAM Milled Methacrylate Complete Removable Dentures based on bone-support concept., CAD/CAM Milled Methacrylate Complete Removable Dentures based on neutral zone concept.
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Edentulous, Jaw
Passive Fit of CAD/CAM Screw-retained Metal Frameworks Versus Screwmented Ones
CAD/CAM (computer aided design/ computer aided manufacturing) constructed screw retained implant supported frameworks give solutions for the problems arising from the lost wax technique by improving accuracy, adaptation and…
- Trial name
- NCT04372901
- Testing
- Digitally constructed frameworks before implant placement, Digitally constructed frameworks after implant placement
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
Evaluation of Prefabricated CAD/CAM PEEK Crowns Used in Primary Molars
Fifty healthy cooperative children will be randomly allocated to two groups. Group I (test group) will receive CAD/CAM PEEK crowns, while group II (control group) will receive SSC.
- Trial name
- NCT06583759
- Testing
- Full coverage Crowns
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Prosthesis (Internal) Complications
Comparison of Prosthetic Complications and Framework Misfit Among Different Cobalt-Chromium Framework Fabrication Techniques
This randomized clinical study aimed to compare prosthetic complications and framework misfit associated with three different fabrication techniques of cobalt-chromium frameworks-conventional casting, CAD/CAM milling, and…
- Trial name
- NCT07489027
- Testing
- Implant supported prosthesis
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Endodontically Treated Molar
Comparison of the Clinical Performance of High Strength Hybrid Ceramic Indirect Restorations Cemented on Endodontically Treated Teeth Using Bioactive Versus Conventional Self Adhesive Resin Cements.
Cementation of indirect restoration is a determinant of the success or failure of the fabricated restoration and consequentially the entire tooth.
- Trial name
- NCT06787469
- Testing
- Resin Cement
- Volunteers
- 50 people
- Sponsor
- Cairo University
Denture, Complete, Jaw, Edentulous
Milled Versus Printed CAD/CAM Complete Dentures
A crossover clinical trial investigates two novel CAD/CAM techniques for complete removable dental prostheses for edentulous patients, milling and rapid prototyping (3D-printing) in a clinical setting of an undergraduate student…
- Trial name
- MILLPRINT (NCT04873219)
- Testing
- manufacturing a complete dental prosthesis
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Tooth Loss, Dental Implant
A 36-month Analysis of the Clinical Performance of Individualized CAD/CAM-produced Dental Implants: a Cohort Study
The goal of this prospective cohort study is to evaluate the clinical performance of a new generation of customized CAD/CAM pre-fabricated root-analog dental implants over a 36-month period.
- Trial name
- NCT06576284
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Transverse Maxillary Deficiency
Digital vs. Analog Inputs in CAD/CAM Orthodontics: A Comparative Clinical Evaluation of Palatal Expander Fabrication Workflow
36 patients with unilateral or bilateral cross bite treated with hyrax expanders fabricated through three distinct workflows: fully conventional (physical impression + manual fabrication), hybrid (physical impression + CAD/CAM…
- Trial name
- NCT07338591
- Where
- 2 sites in Egypt
- Volunteers
- 36 people
- Sponsor
- Mansoura University
Dental Crown
A Comparative Clinical Study to Evaluate Crowns Designed by Artificial Intelligence Versus Crowns Designed Traditional Design Software
This clinical research aims to Evaluate Crowns Designed by Artificial Intelligence Versus Crowns Designed by Traditional Design Software The research will be conducted on a sample of patients with an indication for crowning of…
- Trial name
- AI (NCT07099261)
- Testing
- Crowns
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Latakia University
Provisional Dental Restorations
Color Stability and Tooth Sensitivity of CAD/CAM and Conventional Provisional Restorations
This prospective randomized clinical study compared the color stability and postoperative tooth sensitivity of provisional restorations fabricated using two CAD/CAM-milled materials (VITA CAD-Temp and Telio CAD) and a…
- Trial name
- NCT07781241
- Testing
- Microfilled Reinforced Polyacrylic Resin Provisional Restoration, PMMA Provisional Restoration, Bis-Acryl Composite Resin Provisional Restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- University of Gaziantep
Speech, Denture, Partial, Removable
Intelligibility and Acoustic Speech Performance of CAD/CAM Milled Titanium Partial Dentures
Partial dentures play a crucial role in restoring oral function and aesthetics for patients with missing teeth. Traditionally, these prostheses have been fabricated using materials such as acrylic resin or cobalt-chromium alloys.
- Conditions
- Speech, Denture, Partial, Removable, CAD-CAM
- Trial name
- NCT06589570
- Testing
- Removable Partial Denture
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Badr University
Missing Teeth, Dentures
Comparison Between Conventional and CAD/CAM Complete Dentures Designed Based on Neutral Zone Concept
A within-subject cross-over study is done on eight completely edentulous patients to compare two different complete removable dentures.
- Trial name
- NCT05990088
- Testing
- Heat Cured Conventional Polymethylmethacrylate Complete Removable Dentures based on neutral zone concept, CAD/CAM Milled Methacrylate Complete Removable Dentures based on neutral zone concept.
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Restoration of Primary Molars With CAD/CAM Crowns
Primary Molars Restoration Using Different Pediatric Crowns.
study aims to compare hybrid ceramic CAD/CAM and prefabricated zirconia ans stainless steel crowns restoring primary molars through In-vivo evaluation of the clinical outcomes in terms of; crown retention, stain resistance and…
- Trial name
- NCT04144062
- Testing
- CAD/CAM crowns
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nehal Salman
Partial Edentulism Class 3
Compare CAD/CAM Metallic RPD to Conventional Metallic RPD in Terms of Oral Health Related Quality of Life
Patients will be randomised to receive CAD/CAM metallic removable partial denture (RPD) followed by Conventional metallic RPD (Group A), or the opposite sequence (Group B), with a 3-month wear duration for each denture and…
- Trial name
- NCT06567262
- Testing
- CAD/CAM metallic removable partial denture, Conventional metallic removable partial denture
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Cairo University
Fractured Tooth, Decayed Tooth
TetricCAD Crown Clinical Study
This investigation will be a clinical trial to study the performance of a new resin-based ceramic material for crowns. The material has been approved by the FDA for patient treatment.
- Conditions
- Fractured Tooth, Decayed Tooth, Unsatisfactory Restoration of Tooth
- Trial name
- NCT03716817
- Testing
- Tetric CAD
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Class II Malocclusion, Mandibular Deficiency
Dentoskeletal Effects of 3D-Printed Fixed Twin Block Versus MARA Appliances in Management of Skeletal Class II
Objective: to evaluate the dentoskeletal effects of CAD/CAM 3D-Printed fixed twin block versus MARA appliances in the management of skeletal class II due to Mandibular Deficiency in Preadolescence Class II malocclusion is…
- Trial name
- NCT07340242
- Testing
- MARA appliance, fixed twin block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
CAD/CAM, Patient Specific Implant
Tooth and Bone-borne Cutting/Repositioning Guide and Patient-specific Implant(PSI)
Dentofacial deformity refers to a group of disorders characterized by malocclusion and facial asymmetry resulting from developmental abnormalities of the maxilla and mandible, which cause morphological and positional anomalies of…
- Conditions
- CAD/CAM, Patient Specific Implant, Orthognathic Surgery, Surgery-first
- Trial name
- PSI (NCT07634276)
- Testing
- bimaxillary surgery(Lefort I and SSRO)
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College